Preparation of .alpha.-6-deoxytetracyclines
    3.
    发明授权
    Preparation of .alpha.-6-deoxytetracyclines 失效
    6-脱氧木糖苷的制备

    公开(公告)号:US4001321A

    公开(公告)日:1977-01-04

    申请号:US624714

    申请日:1975-10-22

    申请人: Hermann Faubl

    发明人: Hermann Faubl

    IPC分类号: C07C103/19

    摘要: Hydrogenation of a mixture prepared from a 6-deoxy-6-demethyl-6-methylenetetracycline compound, and a catalytic amount of a dicarboxylato(triphenylphosphine)rhodium(II) or dicarboxylato(substituted triphenylphosphine)rhodium(II) compound, in a reaction-inert solvent, produces the corresponding 6-deoxytetracycline compound. The hydrogenation takes place with a stereoselectivity which favors the 6.alpha.-isomer over the 6.beta.-isomer. The products are known antibacterial agents.

    Biomedical devices with polyimide coating
    5.
    发明授权
    Biomedical devices with polyimide coating 失效
    具有聚酰亚胺涂层的生物医学装置

    公开(公告)号:US06942695B1

    公开(公告)日:2005-09-13

    申请号:US09286530

    申请日:1999-04-05

    摘要: Intraocular lenses and methods producing the same are provided. The intraocular lens includes an optic and a haptic that are integrally formed together. The haptic has a polyimide coating. The polyimide coating promotes fibrosis in the surrounding eye tissue to enhance the anchoring of the IOL after it is implanted in an eye.

    摘要翻译: 提供了人工晶状体及其制造方法。 眼内透镜包括一体地形成在一起的光学元件和触觉元件。 触觉具有聚酰亚胺涂层。 聚酰亚胺涂层促进周围眼组织中的纤维化,以增强IOL在植入眼睛后的锚定。

    UV blocking lenses and material containing benzotriazoles and benzophenones
    8.
    发明授权
    UV blocking lenses and material containing benzotriazoles and benzophenones 失效
    UV阻挡透镜和含有苯并三唑和二苯甲酮的材料

    公开(公告)号:US06244707B1

    公开(公告)日:2001-06-12

    申请号:US09121071

    申请日:1998-07-21

    申请人: Hermann Faubl

    发明人: Hermann Faubl

    IPC分类号: G02C704

    CPC分类号: G02B1/043

    摘要: Contact lenses, intraocular lenses and transparent plastic with enhanced UV blocking to meet ANSI Class 1 specifications include enhanced effective amounts of two different UV absorbing compounds. One UV absorber is a benzotriazole derivative, and the other UV absorber is a benzophenone derivative. The lenses are made from a polymer that incorporates both of these UV absorbers.

    摘要翻译: 隐形眼镜,眼内透镜和透明塑料,具有增强的紫外线阻隔,符合ANSI Class 1规格,包括增加有效量的两种不同的紫外线吸收化合物。 一种UV吸收剂是苯并三唑衍生物,另一种UV吸收剂是二苯甲酮衍生物。 透镜由包含这两种UV吸收剂的聚合物制成。

    Interferon induction in animals by amines
    9.
    发明授权
    Interferon induction in animals by amines 失效
    通过胺对动物进行干扰素诱导

    公开(公告)号:US4491583A

    公开(公告)日:1985-01-01

    申请号:US514670

    申请日:1983-07-18

    摘要: A process for inducing the production of endogenous interferon in a vertebrate animal which comprises parenterally, intranasally or topically adminstering to the animal an interferon-inducing effective amount of composition containing as the essential active ingredient a compound of the formula ##STR1## or a non-toxic acid addition salt thereof wherein R.sub.7 and R.sub.8 are each alkyl of from 12 to 30 carbon atoms and Z is selected from the group consisting of N-(lower alkyl)-piperazino and N-(W-hydroxy-lower alkyl)-piperazino, said lower alkyl groups having from 1 to 4 carbon atoms.

    摘要翻译: 一种在脊椎动物中诱导产生内源性干扰素的方法,其包括肠胃外,鼻内或局部施用给动物干扰素诱导的有效量的组合物,其含有作为必需活性成分的式IMA化合物或非 - 其中R 7和R 8各自为12至30个碳原子的烷基,Z选自N-(低级烷基) - 哌嗪基和N-(W-羟基 - 低级烷基) - 哌嗪基, 所述低级烷基具有1至4个碳原子。