摘要:
Intraocular lenses and methods producing the same are provided. The intraocular lens includes an optic and a haptic that are integrally formed together. The haptic has a polyimide coating. The polyimide coating promotes fibrosis in the surrounding eye tissue to enhance the anchoring of the IOL after it is implanted in an eye.
摘要:
Novel O-alkylsilyl derivatives of macrolide antibiotics are disclosed. These compounds have markedly superior taste properties when compared to the corresponding parent compounds.
摘要:
Hydrogenation of a mixture prepared from a 6-deoxy-6-demethyl-6-methylenetetracycline compound, and a catalytic amount of a dicarboxylato(triphenylphosphine)rhodium(II) or dicarboxylato(substituted triphenylphosphine)rhodium(II) compound, in a reaction-inert solvent, produces the corresponding 6-deoxytetracycline compound. The hydrogenation takes place with a stereoselectivity which favors the 6.alpha.-isomer over the 6.beta.-isomer. The products are known antibacterial agents.
摘要:
Catalyst produced by the process of reacting 1 mol of rhodium trichloride and 2 mols of sodium acetate in methanol at a temperature from about 50.degree.C. to the reflux temperature of said reaction mixture, then reacting resulting reaction mixture with 2 mols of triphenylphosphine at a temperature of from about 50.degree.C. to the reflux temperature of said reaction mixture and recovering resulting insoluble material and use thereof in hydrogenating 6-deoxy-6-demethy-6-methylene-5-oxytetracycline to obtain .alpha.-6-deoxy-5-oxytetracycline.
摘要:
A new process for the production of citric acid, and intermediates therefor of the formula: ##SPC1##Wherein R' is cyano or CO-R.sup.2, wherein R.sup.2 is lower alkoxy, amino or hydroxy.
摘要:
Compounds of the formula ##STR1## or a non-toxic acid addition salt thereof wherein R.sub.1 is alkyl of from 1 to 20 carbon atoms;R.sub.2 is alkyl of from 12 to 20 carbon atoms;R.sub.3 is selected from the group consisting of hydrogen and hydroxyalkyl of from 2 to 8 carbon atoms; andR.sub.4 is selected from the group consisting of hydrogen, alkyl of from 1 to 8 carbon atoms and hydroxyalkyl of from 2 to 8 carbon atoms, said compounds are useful for combating viral infections in vertebrate animals.
摘要:
Contact lenses, intraocular lenses and transparent plastic with enhanced UV blocking to meet ANSI Class 1 specifications include enhanced effective amounts of two different UV absorbing compounds. One UV absorber is a benzotriazole derivative, and the other UV absorber is a benzophenone derivative. The lenses are made from a polymer that incorporates both of these UV absorbers.
摘要翻译:隐形眼镜,眼内透镜和透明塑料,具有增强的紫外线阻隔,符合ANSI Class 1规格,包括增加有效量的两种不同的紫外线吸收化合物。 一种UV吸收剂是苯并三唑衍生物,另一种UV吸收剂是二苯甲酮衍生物。 透镜由包含这两种UV吸收剂的聚合物制成。
摘要:
A process for inducing the production of endogenous interferon in a vertebrate animal which comprises parenterally, intranasally or topically adminstering to the animal an interferon-inducing effective amount of composition containing as the essential active ingredient a compound of the formula ##STR1## or a non-toxic acid addition salt thereof wherein R.sub.7 and R.sub.8 are each alkyl of from 12 to 30 carbon atoms and Z is selected from the group consisting of N-(lower alkyl)-piperazino and N-(W-hydroxy-lower alkyl)-piperazino, said lower alkyl groups having from 1 to 4 carbon atoms.