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    CYCLIC MALTOSYLMALTOSE, CYCLIC MALTOSYMALTOSE-FORMING ENZYME, THEIR PREPARATION AND USES
    2.
    发明申请
    CYCLIC MALTOSYLMALTOSE, CYCLIC MALTOSYMALTOSE-FORMING ENZYME, THEIR PREPARATION AND USES 有权
    环状麦芽糖醇，环状麦芽糖醇形成酶，其制备和用途

    公开(公告)号：US20100015671A1

    公开(公告)日：2010-01-21

    申请号：US11941862

    申请日：2007-11-16

    申请人： Kazuhisa Mukai ,  Hikaru Watanabe ,  Tomoyuki Nishimoto ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Kazuhisa Mukai ,  Hikaru Watanabe ,  Tomoyuki Nishimoto ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： C12P19/18 ,  C12N9/10

    CPC分类号： A61K9/2018 ,  A21D2/181 ,  A23L2/52 ,  A23L2/60 ,  A23L13/428 ,  A23L27/33 ,  A23L33/10 ,  A61K8/60 ,  A61Q11/00 ,  C07H3/06 ,  C12N9/1048 ,  C12P19/18

    摘要： An object of the present invention is to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme forming the non-reducing saccharide, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the non-reducing saccharide, and uses thereof. The present invention solves the above object by providing a novel cyclic saccharide having a structure of cyclo{>6)-α-D-glucopyranosyl-(1>4)-α-D-glucopyranosyl-(1>6)-α-D-glucopyranosyl-(1>4)-α-D-glucopyranosyl-(1>}, cyclic maltosylmaltose, novel cyclic maltosylmaltose-forming enzyme, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the cyclic maltosylmaltose or a saccharide composition comprising the same, and uses thereof.

    摘要翻译： 本发明的目的是通过提供一种由葡萄糖组成的新型非还原性糖组成并提供形成非还原性糖的新型酶，提供一种非还原性糖的方法及其制备方法 ，编码该酶的DNA，重组DNA和包含该DNA的转化体，包含非还原性糖的组合物及其用途。 本发明通过提供具有环{> 6）-α-D-吡喃葡萄糖基 - （1,4）-alpha-D-吡喃葡萄糖基 - （1,6）-alpha-D结构的新型环状糖来解决上述目的 - 吡喃葡萄糖基 - （1,4）-alpha-D-吡喃葡萄糖基 - （1>），环状麦芽糖基麦芽糖，新的环状麦芽糖基麦芽糖酶形成酶，其制备方法和方法，编码该酶的DNA，重组DNA和转化体 包含该DNA，包含环状麦芽糖麦芽糖的组合物或包含其的糖组合物及其用途。

    Isocyclomaltooligosaccharide (S) , isocyclomaltooligosaccharide-forming enzyme, their preparation and uses
    3.
    发明授权
    Isocyclomaltooligosaccharide (S) , isocyclomaltooligosaccharide-forming enzyme, their preparation and uses 有权
    异环寡糖（S），异环寡糖寡糖形成酶，其制备和用途

    公开(公告)号：US07732426B2

    公开(公告)日：2010-06-08

    申请号：US11663919

    申请日：2005-09-26

    申请人： Hikaru Watanabe ,  Tomoyuki Nishimoto ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Hikaru Watanabe ,  Tomoyuki Nishimoto ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： A61K31/715 ,  A61K31/702 ,  C07H1/00

    CPC分类号： C07H3/06 ,  A23L29/35 ,  A23L33/25 ,  C12N9/2402 ,  C12N9/2405 ,  C12P19/04

    摘要： The present invention have objects to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme forming the non-reducing saccharide, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the non-reducing saccharide, and uses thereof. The present invention solves the above objects by providing an isocyclomaltooligosaccharide(s) having a structure represented by General Formula 1, a novel isocyclomaltooligosaccharide-forming enzyme, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the isocyclomaltooligosaccharide(s) or a saccharide composition comprising the same, and uses thereof. Cyclo{→6)-[α-D-Glcp-(1→4)]n-α-D-Glcp-(1→}  General Formula 1 (In General Formula 1, “n” means a number of 4 or 5).

    摘要翻译： 本发明的目的是提供一种由葡萄糖组成的新型非还原性糖组成的非还原性糖类，提供形成非还原性糖类的新型酶，其制造方法及其制造方法， 编码酶的DNA，重组DNA和包含DNA的转化体，包含非还原性糖的组合物及其用途。 本发明通过提供具有由通式1表示的结构的异环型低聚半乳糖，新型的异环型低聚葡萄糖形成酶，其制备方法和方法，编码该酶的DNA，重组DNA和转化体来解决上述目的 包含DNA，包含异环寡脱醇糖的组合物或包含该组合物的糖组合物及其用途。 环状{→6） - [α-D-Glcp-（1→4）] n-α-D-Glcp-（1→}通式1（在通式1中，“n”表示4或5 ）。

    Cyclic maltosylmatose
    4.
    发明授权
    Cyclic maltosylmatose 有权
    循环麦芽糖

    公开(公告)号：US07309697B2

    公开(公告)日：2007-12-18

    申请号：US10569959

    申请日：2004-08-26

    申请人： Kazuhisa Mukai ,  Hikaru Watanabe ,  Tomoyuki Nishimoto ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Kazuhisa Mukai ,  Hikaru Watanabe ,  Tomoyuki Nishimoto ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： A61K31/715 ,  C07H1/00

    CPC分类号： A61K9/2018 ,  A21D2/181 ,  A23L2/52 ,  A23L2/60 ,  A23L13/428 ,  A23L27/33 ,  A23L33/10 ,  A61K8/60 ,  A61Q11/00 ,  C07H3/06 ,  C12N9/1048 ,  C12P19/18

    摘要： An object of the present invention is to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme forming the non-reducing saccharide, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the non-reducing saccharide, and uses thereof. The present invention solves the above object by providing a novel cyclic saccharide having a structure of cyclo{→6)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→6)-α-D-glucopyranosyl-(1→4)-α-D-glucopyranosyl-(1→6}, cyclic maltosylmaltose, novel cyclic maltosylmaltose-forming enzyme, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the cyclic maltosylmaltose or a saccharide composition comprising the same, and uses thereof.

    摘要翻译： 本发明的目的是通过提供一种由葡萄糖组成的新型非还原性糖组成并提供形成非还原性糖的新型酶，提供一种非还原性糖的方法及其制备方法 ，编码该酶的DNA，重组DNA和包含该DNA的转化体，包含非还原性糖的组合物及其用途。 本发明通过提供具有环{ - > 6）-α-D-吡喃葡萄糖基 - （1-> 4）-α-D-吡喃葡萄糖基 - （1-> 6） - 结构的新型环状糖来解决上述目的。 α-D-吡喃葡萄糖基 - （1-> 4）-α-D-吡喃葡萄糖基 - （1-> 6），环状麦芽糖基麦芽糖，新型环状麦芽糖基麦芽糖酶形成酶，其制备方法和方法，编码酶 ，重组DNA和包含该DNA的转化体，包含环状麦芽糖基麦芽糖的组合物或包含其的糖组合物及其用途。

    Process for producing isomaltose and uses thereof
    5.
    发明授权
    Process for producing isomaltose and uses thereof 有权
    异麦芽糖的制备方法及其用途

    公开(公告)号：US07709230B2

    公开(公告)日：2010-05-04

    申请号：US11777044

    申请日：2007-07-12

    申请人： Michio Kubota ,  Tomoyuki Nishimoto ,  Takanobu Higashiyama ,  Hikaru Watanabe ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Michio Kubota ,  Tomoyuki Nishimoto ,  Takanobu Higashiyama ,  Hikaru Watanabe ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： C12P19/44 ,  C12P19/18 ,  C12P19/04 ,  C12N9/00 ,  C12N9/10 ,  C12P21/06 ,  C07H1/00

    CPC分类号： C12P19/12

    摘要： A novel process for producing isomaltose and uses thereof and comprising the steps of contacting saccharides, which have a glucose polymerization degree of at least two and α-1,4 glucosidic linkage as a linkage at the non-reducing end, with an α-isomaltosylglucosaccharide-forming enzyme, in the presence or the absence of α-isomaltosyl-transferring enzyme to form a-isomaltosylglucosaccharides, which have a glucose polymerization degree of at least three, α-1,6 glucosidic linkage as a linkage at the non-reducing end, and α-1,4 glucosidic linkage as a linkage other than the non-reducing end, and/or to form cyclo{→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→}; contacting the saccharides so formed with isomaltose-releasing enzyme to release isomaltose; and collecting the released isomaltose; and uses thereof.

    摘要翻译： 一种生产异麦芽糖的新方法及其应用，包括以下步骤：将非还原末端具有至少两个葡萄糖聚合度和至少两个α-1,4糖苷键作为键的糖与α-异麦芽糖基葡萄糖 在α-异麦芽糖基转移酶的存在或不存在下形成α-异麦芽糖基葡糖，其在非还原末端具有至少三个α-1,6糖苷键作为键的葡萄糖聚合度 和α-1,4糖苷键作为非还原端以外的键，和/或形成环{→6）-α-D-吡喃葡萄糖基 - （1→3）-α-D-吡喃葡萄糖基 - （ 1→6）-α-D-吡喃葡萄糖基 - （1→3）-α-D-吡喃葡萄糖基 - （1→};使与异麦芽糖释放酶形成的糖接触释放异麦芽糖;收集释放的异麦芽糖; 其中。

    Cyclic maltosylmaltose, cyclic maltosymaltose-forming enzyme, their preparation and uses
    7.
    发明授权
    Cyclic maltosylmaltose, cyclic maltosymaltose-forming enzyme, their preparation and uses 有权
    循环麦芽糖苷，环状麦芽糖基酶形成酶，其制备和用途

    公开(公告)号：US07951530B2

    公开(公告)日：2011-05-31

    申请号：US11941862

    申请日：2007-11-16

    申请人： Kazuhisa Mukai ,  Hikaru Watanabe ,  Tomoyuki Nishimoto ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Kazuhisa Mukai ,  Hikaru Watanabe ,  Tomoyuki Nishimoto ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： G01N33/573 ,  C12Q1/48 ,  C12P1/00 ,  C13K7/00 ,  C07H1/00

    CPC分类号： A61K9/2018 ,  A21D2/181 ,  A23L2/52 ,  A23L2/60 ,  A23L13/428 ,  A23L27/33 ,  A23L33/10 ,  A61K8/60 ,  A61Q11/00 ,  C07H3/06 ,  C12N9/1048 ,  C12P19/18

    摘要： An object of the present invention is to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme forming the non-reducing saccharide, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the non-reducing saccharide, and uses thereof. The present invention solves the above object by providing a novel cyclic saccharide having a structure of cyclo{>6)-α-D-glucopyranosyl-(1>4)-α-D-glucopyranosyl-(1>6)-α-D-glucopyranosyl-(1>4)-α-D-glucopyranosyl-(1>}, cyclic maltosylmaltose, novel cyclic maltosylmaltose-forming enzyme, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the cyclic maltosylmaltose or a saccharide composition comprising the same, and uses thereof.

    摘要翻译： 本发明的目的是通过提供一种由葡萄糖组成的新型非还原性糖组成并提供形成非还原性糖的新型酶，提供一种非还原性糖的方法及其制备方法 ，编码该酶的DNA，重组DNA和包含该DNA的转化体，包含非还原性糖的组合物及其用途。 本发明通过提供具有环{（6）-α-D-吡喃葡萄糖基 - （1,4）-α-D-吡喃葡萄糖基 - （1,6）-α-D结构的新型环状糖来解决上述目的 - 吡喃葡萄糖基 - （1> 4）-α-D-吡喃葡萄糖基 - （1>），环状麦芽糖基麦芽糖，新型环状麦芽糖基麦芽糖酶形成酶，其制备方法和方法，编码该酶的DNA，重组DNA和转化体 包含该DNA，包含环状麦芽糖麦芽糖的组合物或包含其的糖组合物及其用途。

    PROCESS FOR PRODUCING ISOMALTOSE AND USES THEREOF
    8.
    发明申请
    PROCESS FOR PRODUCING ISOMALTOSE AND USES THEREOF 有权
    生产异构体的方法及其用途

    公开(公告)号：US20080241904A1

    公开(公告)日：2008-10-02

    申请号：US11777044

    申请日：2007-07-12

    申请人： Michio Kubota ,  Tomoyuki Nishimoto ,  Takanobu Higashiyama ,  Hikaru Watanabe ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Michio Kubota ,  Tomoyuki Nishimoto ,  Takanobu Higashiyama ,  Hikaru Watanabe ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： C12N9/10

    CPC分类号： C12P19/12

    摘要： A novel process for producing isomaltose and uses thereof and comprising the steps of contacting saccharides, which have a glucose polymerization degree of at least two and α-1,4 glucosidic linkage as a linkage at the non-reducing end, with an α-isomaltosylglucosaccharide-forming enzyme, in the presence or the absence of α-isomaltosyl-transferring enzyme to form a-isomaltosylglucosaccharides, which have a glucose polymerization degree of at least three, α-1,6 glucosidic linkage as a linkage at the non-reducing end, and α-1,4 glucosidic linkage as a linkage other than the non-reducing end, and/or to form cyclo{→6)-α-D-glucopyranosyl-(1→3)-α-D-glucopyranosyl-(1→6)-α-D-glucopyranosyl-(1″3)-α-D-glucopyranosyl-(1→}; contacting the saccharides so formed with isomaltose-releasing enzyme to release isomaltose; and collecting the released isomaltose; and uses thereof.

    摘要翻译： 一种制备异麦芽糖的新方法及其用途，包括以下步骤：将具有至少两个葡萄糖聚合度的至少两个和非1,4-还原末端的α-1,4糖苷键的糖与α-异麦芽糖基葡萄糖 在α-异麦芽糖基转移酶的存在或不存在下形成α-异麦芽糖基糖，其具有在非还原末端具有至少三个α-1,6糖苷键作为键的葡萄糖聚合度 和α-1,4糖苷键作为非还原末端之外的键，和/或形成环{ - > 6）-al-D-glucopyranosyl-（1-> 3）-al-D-glucopyranosyl - （1-> 6）-al-D-glucopyranosyl-（1''3）-alpha-D-吡喃葡萄糖基 - （1->};使所形成的糖与异麦芽糖释放酶接触以释放异麦芽糖; 释放的异麦芽糖;及其用途。

    Isocyclomaltooligosaccharide (S) , Isocyclomaltooligosaccharide-Forming Enzyme, Their Preparation and Uses
    9.
    发明申请
    Isocyclomaltooligosaccharide (S) , Isocyclomaltooligosaccharide-Forming Enzyme, Their Preparation and Uses 有权
    异环寡糖（S），异环寡糖 - 形成酶，其制备及用途

    公开(公告)号：US20080131468A1

    公开(公告)日：2008-06-05

    申请号：US11663919

    申请日：2005-09-26

    申请人： Hikaru Watanabe ,  Tomoyuki Nishimoto ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    发明人： Hikaru Watanabe ,  Tomoyuki Nishimoto ,  Michio Kubota ,  Shigeharu Fukuda ,  Toshio Miyake

    IPC分类号： A61K8/02 ,  C13K5/00 ,  C12N9/00 ,  C12N1/20 ,  A61K31/715 ,  A23L2/38 ,  A23G3/00 ,  C07H21/04 ,  C12N1/00 ,  C12P19/12

    CPC分类号： C07H3/06 ,  A23L29/35 ,  A23L33/25 ,  C12N9/2402 ,  C12N9/2405 ,  C12P19/04

    摘要： The present invention have objects to provide an option of non-reducing saccharide by providing a novel non-reducing saccharide composed of glucose as constituents and to provide a novel enzyme forming the non-reducing saccharide, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the non-reducing saccharide, and uses thereof. The present invention solves the above objects by providing an isocyclomaltooligosaccharide(s) having a structure represented by General Formula 1, a novel isocyclomaltooligosaccharide-forming enzyme, a method and process for producing the same, a DNA encoding the enzyme, a recombinant DNA and transformant comprising the DNA, a composition comprising the isocyclomaltooligosaccharide (s) or a saccharide composition comprising the same, and uses thereof. Cyclo{→6)-[α-D-Glcp-(1→4)]n-α-D-Glcp-(1→}General Formula 1 (In General Formula 1, “n” means a number of 4 or 5)

    摘要翻译： 本发明的目的是提供一种由葡萄糖组成的新型非还原性糖组成的非还原性糖类，提供形成非还原性糖类的新型酶，其制造方法及其制造方法， 编码酶的DNA，重组DNA和包含DNA的转化体，包含非还原性糖的组合物及其用途。 本发明通过提供具有由通式1表示的结构的异环型低聚半乳糖，新型的异环型低聚葡萄糖形成酶，其制备方法和方法，编码该酶的DNA，重组DNA和转化体来解决上述目的 包含DNA，包含异环寡脱醇糖的组合物或包含该组合物的糖组合物及其用途。 <？in-line-formula description =“In-line Formulas”end =“lead”？> Cyclo { - > 6） - [alpha-D-Glcp-（1→4）] }通式1 <？in-line-formula description =“In-line Formulas”end =“tail”？>（在通用公式1中，“n” 4或5）