利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

27 条记录 (耗时 0.019 秒)

    Diagnostic agent for angiopathic diseases
    1.
    发明授权
    Diagnostic agent for angiopathic diseases 失效
    血管疾病诊断剂

    公开(公告)号：US06270744B1

    公开(公告)日：2001-08-07

    申请号：US09125430

    申请日：1999-01-04

    申请人： Tsutomu Iwasaki ,  Ryozo Nagai ,  Hirohisa Katoh

    发明人： Tsutomu Iwasaki ,  Ryozo Nagai ,  Hirohisa Katoh

    IPC分类号： A61K5100

    CPC分类号： A61K51/1018 ,  A61K51/10

    摘要： A diagnostic agent for angiopathic diseases containing a monoclonal antibody against human smooth muscle myosin or active fragments of the antibody labeled with a radioactive isotope; a kit thereof; and a method of diagnostic imaging for angiopathic diseases by using the same. The invention permits the diagnostic imaging of angiopathic diseases such as dissecting aortic aneurysm and angiitis and the specification of the region affected by these diseases.

    摘要翻译： 含有针对人平滑肌肌球蛋白的单克隆抗体或用放射性同位素标记的抗体的活性片段的血管病变的诊断剂; 其套件; 以及通过使用该方法对血管病变进行诊断成像的方法。 本发明允许血管病变的诊断成像，例如解剖主动脉瘤和血管炎以及受这些疾病影响的区域的规格。

    ADIPONECTIN RECEPTOR AND GENE ENCODING THE SAME
    7.
    发明申请
    ADIPONECTIN RECEPTOR AND GENE ENCODING THE SAME 有权
    ADIPONECTIN受体和编码其的基因

    公开(公告)号：US20120027760A1

    公开(公告)日：2012-02-02

    申请号：US13153017

    申请日：2011-06-03

    申请人： Takashi KADOWAKI ,  Toshimasa Yamauchi ,  Ryozo Nagai ,  Junji Kamon

    发明人： Takashi KADOWAKI ,  Toshimasa Yamauchi ,  Ryozo Nagai ,  Junji Kamon

    IPC分类号： C07K16/18 ,  A61K39/395 ,  C12N5/12

    CPC分类号： C07K14/72 ,  Y10S435/81

    摘要： The object is to isolate and identify human and mouse adiponectin receptors, to provide a novel protein having adiponectin binding ability, and to provide a screening method and screening kit for a ligand, agonist and antagonist to an adiponectin receptor using such protein. To achieve this object, a protein is used, as novel protein having adiponectin binding ability, that is (a) a protein comprising an amino acid sequence according to Seq. No. 2, 4, 6 or 8, or (b) a protein comprising an amino acid sequence according to Seq. No. 2, 4, 6 or 8 with one or more amino acids deleted, replaced or added, and having adiponectin binding ability.

    摘要翻译： 目的是分离和鉴定人和小鼠脂联素受体，以提供具有脂联素结合能力的新型蛋白质，并提供使用这种蛋白质的脂联素受体的配体，激动剂和拮抗剂的筛选方法和筛选试剂盒。 为了实现这个目的，使用蛋白质作为具有脂联素结合能力的新型蛋白质，即（a）包含根据Seq的氨基酸序列的蛋白质。 No.2,4,6或8，或（b）包含根据Seq的氨基酸序列的蛋白质。 具有一个或多个缺失，替换或添加的氨基酸并具有脂联素结合能力的2,4,6或8号。

    Adiponectin receptor and gene encoding the same
    9.
    发明授权
    Adiponectin receptor and gene encoding the same 有权
    脂联素受体和基因编码相同

    公开(公告)号：US08252584B2

    公开(公告)日：2012-08-28

    申请号：US13153017

    申请日：2011-06-03

    申请人： Takashi Kadowaki ,  Toshimasa Yamauchi ,  Ryozo Nagai ,  Junji Kamon

    发明人： Takashi Kadowaki ,  Toshimasa Yamauchi ,  Ryozo Nagai ,  Junji Kamon

    IPC分类号： C12N5/07 ,  C12N5/16 ,  C07K16/00 ,  C12P21/08

    CPC分类号： C07K14/72 ,  Y10S435/81

    摘要： The object is to isolate and identify human and mouse adiponectin receptors, to provide a novel protein having adiponectin binding ability, and to provide a screening method and screening kit for a ligand, agonist and antagonist to an adiponectin receptor using such protein. To achieve this object, a protein is used, as novel protein having adiponectin binding ability, that is (a) a protein comprising an amino acid sequence according to Seq. No. 2, 4, 6 or 8, or (b) a protein comprising an amino acid sequence according to Seq. No. 2, 4, 6 or 8 with one or more amino acids deleted, replaced or added, and having adiponectin binding ability.

    摘要翻译： 目的是分离和鉴定人和小鼠脂联素受体，以提供具有脂联素结合能力的新型蛋白质，并提供使用这种蛋白质的脂联素受体的配体，激动剂和拮抗剂的筛选方法和筛选试剂盒。 为了实现这个目的，使用蛋白质作为具有脂联素结合能力的新型蛋白质，即（a）包含根据Seq的氨基酸序列的蛋白质。 No.2,4,6或8，或（b）包含根据Seq的氨基酸序列的蛋白质。 具有一个或多个缺失，替换或添加的氨基酸并具有脂联素结合能力的2,4,6或8号。

    Adiponectin receptor and gene encoding the same
    10.
    发明授权
    Adiponectin receptor and gene encoding the same 有权
    脂联素受体和基因编码相同

    公开(公告)号：US07977459B2

    公开(公告)日：2011-07-12

    申请号：US12322111

    申请日：2009-01-29

    申请人： Takashi Kadowaki ,  Toshimasa Yamauchi ,  Ryozo Nagai ,  Junji Kamon

    发明人： Takashi Kadowaki ,  Toshimasa Yamauchi ,  Ryozo Nagai ,  Junji Kamon

    IPC分类号： C07K1/00 ,  G01N33/53 ,  G01N33/566

    CPC分类号： C07K14/72 ,  Y10S435/81

    摘要： The object is to isolate and identify human and mouse adiponectin receptors, to provide a novel protein having adiponectin binding ability, and to provide a screening method and screening kit for a ligand, agonist and antagonist to an adiponectin receptor using such protein. To achieve this object, a protein is used, as novel protein having adiponectin binding ability, that is (a) a protein comprising an amino acid sequence according to Seq. No. 2, 4, 6 or 8, or (b) a protein comprising an amino acid sequence according to Seq. No. 2, 4, 6 or 8 with one or more amino acids deleted, replaced or added, and having adiponectin binding ability.

    摘要翻译： 目的是分离和鉴定人和小鼠脂联素受体，以提供具有脂联素结合能力的新型蛋白质，并提供使用这种蛋白质的脂联素受体的配体，激动剂和拮抗剂的筛选方法和筛选试剂盒。 为了实现这个目的，使用蛋白质作为具有脂联素结合能力的新型蛋白质，即（a）包含根据Seq的氨基酸序列的蛋白质。 No.2,4,6或8，或（b）包含根据Seq的氨基酸序列的蛋白质。 具有一个或多个缺失，替换或添加的氨基酸并具有脂联素结合能力的2,4,6或8号。