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    Flea control agent containing N-Substituted indole derivative
    4.
    发明申请
    Flea control agent containing N-Substituted indole derivative 审中-公开
    含有N-取代吲哚衍生物的跳蚤控制剂

    公开(公告)号：US20090270459A1

    公开(公告)日：2009-10-29

    申请号：US12456823

    申请日：2009-06-22

    申请人： Satoshi Tanabe ,  Hiroki Hotta ,  Tetsuya Toya ,  Katsuhiko Hosoda

    发明人： Satoshi Tanabe ,  Hiroki Hotta ,  Tetsuya Toya ,  Katsuhiko Hosoda

    IPC分类号： A01N43/38 ,  A01N43/40 ,  A01P7/04

    CPC分类号： A01N43/38 ,  A01N43/40

    摘要： Conventional control agents against fleas parasitic on animals do not have sufficient selective toxicity and are hence not safe for the animals to which the control agents are applied. The control agents are not always satisfactory also in control effect and quick-acting properties. Intensive studies were made on the insecticidal activity of N-substituted indole compounds against fleas and on the safety thereof for mammals including pets. As a result, it was found that an N-substituted indole derivative, e.g., 1-(3-chloro-5-trifluoromethylpyridin 2-yl)-3-(dichlorofluoromethylthio)indole, 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-(dichlorofluoromethylthio)-indole, or 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-(trifluoromethylthio)indole, has high insecticidal activity and quick-acting properties and is lowly toxic to mammals including pets.

    摘要翻译： 防止寄生在动物上的跳蚤的传统控制剂不具有足够的选择性毒性，因此对于施用控制剂的动物是不安全的。 在控制效果和速效特性方面，控制剂并不总是令人满意。 对N-取代吲哚化合物对跳蚤的杀虫活性及其对哺乳动物（包括宠物）的安全性进行了深入研究。 结果发现，N-取代的吲哚衍生物，例如1-（3-氯-5-三氟甲基吡啶-2-基）-3-（二氯氟甲硫基）吲哚，1-（2,6-二氯-4- 三氟甲基苯基）-3-（二氯氟甲硫基） - 吲哚或1-（2,6-二氯-4-三氟甲基苯基）-3-（三氟甲硫基）吲哚具有很高的杀虫活性和速效性，对包括宠物在内的哺乳动物具有低毒性 。

    Control agent containing N-Substituted indole derivative for acarian parasitic on animal
    5.
    发明申请
    Control agent containing N-Substituted indole derivative for acarian parasitic on animal 审中-公开
    含有N-取代吲哚衍生物的控制剂用于动物的寄生虫

    公开(公告)号：US20100056601A1

    公开(公告)日：2010-03-04

    申请号：US12590367

    申请日：2009-11-06

    申请人： Satoshi Tanabe ,  Hiroki Hotta ,  Tetsuya Toya ,  Katsuhiko Hosoda

    发明人： Satoshi Tanabe ,  Hiroki Hotta ,  Tetsuya Toya ,  Katsuhiko Hosoda

    IPC分类号： A61K31/404

    CPC分类号： A01N47/02 ,  A01N43/38 ,  A01N43/40

    摘要： Conventional control agents against acarians parasitic on animals do not have sufficient selective toxicity and are hence not safe for the animals to which the control agents are applied. The control agents are not always satisfactory also in control effect and quick-acting properties. Intensive studies were made on the insecticidal activity of N-substituted indole compounds against acarians and on the safety thereof for mammals including pets. As a result, it was found that an N-substituted indole derivative, e.g., 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-(trifluoromethylthio)indole, or 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-(dichlorofluoromethylthio)indole, has high insecticidal activity and quick-acting properties and is lowly toxic to mammals including pets.

    摘要翻译： 对动物寄生寄生虫的传统控制剂不具有足够的选择性毒性，因此对施用对照剂的动物来说是不安全的。 在控制效果和速效特性方面，控制剂并不总是令人满意。 对N-取代吲哚化合物对猕猴桃的杀虫活性及其对哺乳动物（包括宠物）的安全性进行了深入研究。 结果发现，N-取代的吲哚衍生物，例如1-（2,6-二氯-4-三氟甲基苯基）-3-（三氟甲硫基）吲哚或1-（2,6-二氯-4- 三氟甲基苯基）-3-（二氯氟甲硫基）吲哚，具有高杀虫活性和速效性，对包括宠物在内的哺乳动物具有低毒性。

    Control agent containing n-substituted indole derivative for acarian parasitic on animal
    6.
    发明申请
    Control agent containing n-substituted indole derivative for acarian parasitic on animal 审中-公开
    含有对取代吲哚衍生物的控制剂用于动物的寄生虫

    公开(公告)号：US20070197578A1

    公开(公告)日：2007-08-23

    申请号：US10593920

    申请日：2004-04-22

    申请人： Satoshi Tanabe ,  Hiroki Hotta ,  Tetsuya Toya ,  Katsuhiko Hosoda

    发明人： Satoshi Tanabe ,  Hiroki Hotta ,  Tetsuya Toya ,  Katsuhiko Hosoda

    IPC分类号： A61K31/44

    CPC分类号： A01N47/02 ,  A01N43/38 ,  A01N43/40

    摘要： Conventional control agents against acarians parasitic on animals do not have sufficient selective toxicity and are hence not safe for the animals to which the control agents are applied. The control agents are not always satisfactory also in control effect and quick-acting properties. Intensive studies were made on the insecticidal activity of N-substituted indole compounds against acarians and on the safety thereof for mammals including pets. As a result, it was found that an N-substituted indole derivative, e.g., 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-(trifuloromethylthio)indole, or 1-(2,6-dichloro-4-trifluoromethylphenyl)-3-(dichlo-rofluoromethylthio)indole, has high insecticidal activity and quick-acting properties and is lowly toxic to mammals including pets.

    摘要翻译： 对动物寄生寄生虫的传统控制剂不具有足够的选择性毒性，因此对施用对照剂的动物来说是不安全的。 在控制效果和速效特性方面，控制剂并不总是令人满意。 对N-取代吲哚化合物对猕猴桃的杀虫活性及其对哺乳动物（包括宠物）的安全性进行了深入研究。 结果发现，N-取代的吲哚衍生物，例如1-（2,6-二氯-4-三氟甲基苯基）-3-（三氟甲硫基）吲哚或1-（2,6-二氯-4- 三氟甲基苯基）-3-（二氯 - 氟甲硫基）吲哚，具有很高的杀虫活性和速效性，对包括宠物在内的哺乳动物具有低毒性。