公开(公告)号：US07740613B2

公开(公告)日：2010-06-22

申请号：US12334270

申请日：2008-12-12

申请人： Hiroyuki Yokoi ,  Yukinori Ebara

发明人： Hiroyuki Yokoi ,  Yukinori Ebara

IPC分类号： A61M37/00 ,  A61M5/178

CPC分类号： A61M5/158 ,  A61M2005/1585 ,  A61M2005/1587

摘要： An inserter includes a housing, a plunger holding an indwelling member, a lifter contained in the housing in the state where the lifter is axially movable relative to the plunger, a needle holder contained in the housing and having a projection that can be latched by the plunger and the lifter, an insertion needle held by the needle holder and inserted in a cannula, and a spring provided between the plunger and the lifter and applying a biasing force in the direction of biasing the plunger and the lifter away from each other. The projection of the needle holder is latched by the plunger before the indwelling member reaches the body surface of the user, and latched by the lifter after the indwelling member reaches the body surface of the user.

摘要翻译： 插入器包括壳体，保持留置构件的柱塞，在升降器相对于柱塞可轴向移动的状态下容纳在壳体中的提升器;容纳在壳体中的针保持器，具有可由 柱塞和提升器，由针保持器保持并插入插管中的插入针和设置在柱塞和升降器之间的弹簧，并且在使柱塞和升降器彼此偏置的方向上施加偏压力。 针座的突起在留置构件到达使用者的身体表面之前被柱塞锁定，并且在留置构件到达使用者的身体表面之后由提升器锁定。

公开(公告)号：US10191038B2

公开(公告)日：2019-01-29

申请号：US14007412

申请日：2012-03-27

申请人： Keiichi Shoji ,  Hiroyuki Yokoi

发明人： Keiichi Shoji ,  Hiroyuki Yokoi

IPC分类号： G01N33/543 ,  G01N33/53

摘要： In a known method of measuring a target substance, comprising: providing a sample solution containing the target substance, a first reaction solution, and a second reaction solution; sequentially aspirating the sample solution and the first reaction solution, using a measuring apparatus equipped with a dispensing unit, into the dispensing unit; discharging them at a time from the dispensing unit, to bring them into contact with the second reaction solution, and to form a complex of the target substance and a first partner which is contained in at least one of the first reaction solution or the second reaction solution and reacts specifically with the target substance; and analyzing the resulting complex, an improved method capable of inhibiting a reaction which adversely affects measurement results is provided. In this improved method, the specific gravity of the sample solution is different from the specific gravity of the first reaction solution; and the sample solution and the first reaction solution are aspirated into the dispensing unit in an overlaid state.

公开(公告)号：US20140127661A1

公开(公告)日：2014-05-08

申请号：US13813332

申请日：2012-07-20

申请人： Hiroyuki Yokoi

发明人： Hiroyuki Yokoi

IPC分类号： G01F3/04 ,  G09B23/28

CPC分类号： G01F3/04 ,  G09B19/24 ,  G09B23/285

摘要： Provided is a syringe operation detection device 1 for detecting a drawing or injecting operation of a plunger 120 in a syringe 100. A female joint part 52 is joined to a barrel tip 116 of the syringe 100, a male joint part 60 is joined to a needle hub 132 of a syringe needle 130, and a coupling container 70 is placed between the female joint part 52 and the male joint part 60, for allowing them to be continuous with each other while being closed externally. A detector for detecting a pressure, flow velocity, or flow rate of a fluid moving therein is placed in any one of the coupling container 70, the female joint part 52, and the male joint part 60. As a result, there is provided the syringe operation detection device capable of being applied to a syringe actually used and evaluating a drawing or injecting state in objective terms.

摘要翻译： 提供了一种用于检测注射器100中的柱塞120的拉拔或注射操作的注射器操作检测装置1.阴连接部52连接到注射器100的筒状末端116，阳接头部60连接到 注射器针头130的针座132和联接容器70放置在阴接头部52和阳接头部60之间，以允许它们在外部被封闭的同时彼此连续。 用于检测其中移动的流体的压力，流速或流速的检测器被放置在联接容器70，阴接头部分52和阳接头部分60中的任一个中。结果， 注射器操作检测装置能够实际应用于实际使用的注射器，并且以客观方式评价绘图或注射状态。

公开(公告)号：US08383421B2

公开(公告)日：2013-02-26

申请号：US11332269

申请日：2006-01-17

申请人： Atsushi Yanagida ,  Takashi Kurihara ,  Hiroyuki Yokoi ,  Atsushi Koyata ,  Yoshikazu Okamura ,  Daishi Miyamoto

发明人： Atsushi Yanagida ,  Takashi Kurihara ,  Hiroyuki Yokoi ,  Atsushi Koyata ,  Yoshikazu Okamura ,  Daishi Miyamoto

IPC分类号： G01N1/10

CPC分类号： B01L3/50851 ,  B01L3/527 ,  B01L2300/021 ,  B01L2300/0809 ,  B01L2300/1883 ,  G01N35/026 ,  Y10T436/25 ,  Y10T436/2575

摘要： An object of the present invention is to provide a cartridge for automatic measurement used in an automatic measuring device, capable of automatically performing measurement including heat treatment of a sample, and a measuring device using the cartridge.The present invention relates to a cartridge for use in measuring a component to be measured contained in a sample, comprising: at least a heat-treatment well for performing heat treatment of the sample; and a reaction well for reacting the component to be measured in the sample with a material specifically reacting therewith.

摘要翻译： 本发明的目的是提供一种用于自动测量的自动测量盒，能够自动执行包括样品的热处理的测量以及使用该盒的测量装置。 本发明涉及一种用于测量样品中包含的待测组分的盒，包括：至少一个用于对样品进行热处理的热处理孔; 以及用于使样品中待测量的组分与其特异性反应的材料反应的反应。

公开(公告)号：US20130225939A1

公开(公告)日：2013-08-29

申请号：US13819856

申请日：2011-07-15

申请人： Hiroyuki Yokoi

发明人： Hiroyuki Yokoi

IPC分类号： A61B10/00

CPC分类号： A61B10/0041 ,  A61B34/76 ,  A61B42/00

摘要： Provided is a glove for sensitizing touch perception with which fingertips can be moved smoothly across a wide area without influencing subtle touch perception and an examination by means of palpation can be performed highly accurately and smoothly.A glove 1 according to the present invention is a glove for sensitizing touch perception that is for use in detecting minute irregularities of an object via a sensitizing layer 2 by means of a hand inserted between the sensitizing layer 2 and an external cover 3. The sensitizing layer 2 includes: a first film 10 to be in contact with the object; a second film 12 layered on the first film 10; and an air introduction opening 14 for introducing air between the first film 10 and the second film 12 to allow the second film 12 to slide relative to the first film 10. The external cover 3 or the sensitizing layer 2 includes a stopper 20 for positioning the tip of a hand inserted between the sensitizing layer 2 and the external cover 3 on the inner side of a peripheral edge of the sensitizing layer 2.

摘要翻译： 提供了一种用于敏感触觉感觉的手套，指尖可以在广泛的区域上平稳地移动，而不影响微妙的触觉感觉，并且可以高精度和平稳地执行触诊的检查。 根据本发明的手套1是用于通过插入在感光层2和外盖3之间的手通过感光层2检测物体的微小凹凸的敏感感觉手套。感光 层2包括：与物体接触的第一膜10; 层叠在第一膜10上的第二膜12; 以及用于在第一膜10和第二膜12之间引入空气以允许第二膜12相对于第一膜10滑动的空气引入开口14.外盖3或敏化层2包括用于将第二膜12定位的止挡件20 在感光层2的周缘的内侧插入感光层2和外罩3之间的手头。

公开(公告)号：US20120309025A1

公开(公告)日：2012-12-06

申请号：US13575604

申请日：2011-01-28

申请人： Yoshikazu Okamura ,  Hiroyuki Yokoi

发明人： Yoshikazu Okamura ,  Hiroyuki Yokoi

IPC分类号： G01N21/76

CPC分类号： G01N33/566 ,  G01N2333/70596 ,  G01N2800/26

摘要： An analysis method capable of accurately measuring human sCD14-ST when using a whole blood sample is provided. In the analysis method, human sCD14-ST in a whole blood sample is analyzed within 6 hours of the collection of the sample.

摘要翻译： 提供了一种能够在使用全血样品时精确测量人sCD14-ST的分析方法。 在分析方法中，在收集样品的6小时内分析全血样品中的人sCD14-ST。

公开(公告)号：US20090131807A1

公开(公告)日：2009-05-21

申请号：US11989021

申请日：2006-07-21

申请人： Hiroyuki Yokoi

发明人： Hiroyuki Yokoi

IPC分类号： A61B5/022

CPC分类号： A61B5/022 ,  A61B5/742

摘要： A blood pressure level display device or the like is provided which allows easy measurement and has an improved convenience during measurement.It has a blood pressure display panel 24 having a circumferentially-calibrated scale, and includes: a systolic blood pressure indicating unit for providing a systolic blood pressure indication based on a state of systolic blood pressure; and a diastolic blood pressure indicating unit for providing a diastolic blood pressure indication based on a state of diastolic blood pressure. It further includes: a high blood pressure side indicator needle 26 which rotates in conjunction with a state of pressure applied to a subject to be measured, and displays at rest a systolic blood pressure level based on the systolic blood pressure indication from the systolic blood pressure indicating unit; and a low blood pressure side indicator needle 28 which displays at rest a diastolic blood pressure level based on the diastolic blood pressure indication from the diastolic blood pressure indicating unit.

摘要翻译： 提供了一种血压显示装置等，其容易测量并且在测量期间具有改进的便利性。 它具有血压显示面板24，该血压显示面板24具有周向校准的刻度，并且包括：收缩压指示单元，用于基于收缩压的状态提供收缩压指示; 以及舒张压指示单元，用于基于舒张压的状态提供舒张压指示。 其还包括：高血压侧指示器针26，其与施加于待测对象的压力状态一起旋转，并且基于来自收缩压的收缩期血压指示静息显示收缩期血压水平 指示单位 和低血压侧指示针28，其基于来自舒张压指示单元的舒张压指示，静息显示舒张血压水平。

公开(公告)号：US07338809B2

公开(公告)日：2008-03-04

申请号：US10657118

申请日：2003-09-09

申请人： Hiroyuki Yokoi

发明人： Hiroyuki Yokoi

IPC分类号： G01N1/00

CPC分类号： G01N33/54393 ,  Y10T436/101666 ,  Y10T436/107497 ,  Y10T436/108331 ,  Y10T436/2525

摘要： In a method for measuring an analyte, which comprises a reaction step of forming a reaction system including a sample containing whole blood, a first substance carried by a solid carrier and specifically binding to an analyte contained in the sample and a second substance specifically binding to the analyte and allowing the analyte to react with the first and second substances and a measurement step of measuring the formed reaction product, (1) the reaction step is performed in a state that blood cells are not disrupted, and (2) at least the reaction step is performed in the presence of a sufficient amount of a detergent that does not cause hemolysis, does not inhibit reactions of the analyte with the first and second substances specifically binding to the analyte and can prevent influence on the reaction system of a component existing in the reaction system.

摘要翻译： 在测定分析物的方法中，其包括形成包含全血的样品的反应体系的反应步骤，固体载体携带的第一物质，特异性结合于样品中所含的分析物，以及特异性结合于 分析物并使分析物与第一和第二物质反应，以及测量形成的反应产物的测量步骤，（1）反应步骤以不破坏血细胞的状态进行，和（2）至少 反应步骤在足够量的洗涤剂的存在下进行，其不引起溶血，不会抑制分析物与特异性结合分析物的第一和第二物质的反应，并且可以防止对存在的成分的反应体系的影响 在反应体系中。

公开(公告)号：US5921232A

公开(公告)日：1999-07-13

申请号：US793095

申请日：1997-04-16

申请人： Hiroyuki Yokoi ,  Masae Shibasaki

发明人： Hiroyuki Yokoi ,  Masae Shibasaki

IPC分类号： A61M15/00 ,  A61M11/00

CPC分类号： A61M15/00 ,  A61M15/0085

摘要： The inhaler has a medicine atomizing means 10, a nozzle 12 for discharging medicine atomized by said medicine atomizing means 10, and a gripping casing 14. Said casing 14 has a small-diametered cylindrical section 14a, a large-diametered cylindrical section 14b, and a bottom 14c, and is formed so as to have a bottom with its upper end side open. Furthermore, the same has a roughly gourd-shaped cross-section which connects said small-diametered cylindrical section 14a and said large-diametered cylindrical section 14b at the side thereof. Said medicine atomizing means 10 is incorporated in the large-diametered cylindrical section 14b side of the casing 14, and has a piezoelectric vibrator 10a and a vibration liquid. Said nozzle 12 is composed of a transparent rubber-based member and is attached in such a manner that the base part side is fitted to the first annular protrusion 46e of the cover 46, whereby it is possible to optionally change the discharging direction of medicine by changing the fitting state of the base part.

摘要翻译： PCT No.PCT / JP95 / 01383第 371日期1997年04月16日 102（e）日期1997年04月16日PCT申报1995年7月12日吸入器具有药物雾化装置10，用于排出由药物雾化装置10雾化的药物的喷嘴12和夹持壳体14.所述壳体14具有 小直径圆筒部14a，大直径圆筒部14b和底部14c，并且形成为具有其上端侧开口的底部。 此外，它们具有将所述小直径圆柱形部分14a和其一侧的大直径圆柱形部分14b连接的大致葫芦形横截面。 所述药剂雾化装置10并入壳体14的大直径圆筒部14b侧，具有压电振动体10a和振动液。 所述喷嘴12由透明的橡胶基部件构成，并且以使得基部侧嵌合到盖46的第一环状突起46e的方式安装，由此可以可选地改变药物的排出方向 改变基部的装配状态。

公开(公告)号：US5866059A

公开(公告)日：1999-02-02

申请号：US682234

申请日：1996-07-17

申请人： Shuzo Fujiwara ,  Masatake Yoshida ,  Yozo Kakudate ,  Shu Usuba ,  Hiroyuki Yokoi ,  Katsutoshi Aoki ,  Masayuki Kawaguchi ,  Tadayuki Kawashima ,  Katsuharu Kasami ,  Tamikuni Komatsu

发明人： Shuzo Fujiwara ,  Masatake Yoshida ,  Yozo Kakudate ,  Shu Usuba ,  Hiroyuki Yokoi ,  Katsutoshi Aoki ,  Masayuki Kawaguchi ,  Tadayuki Kawashima ,  Katsuharu Kasami ,  Tamikuni Komatsu

IPC分类号： C01B31/30 ,  B01J3/08 ,  C01B21/082 ,  C01B35/14 ,  C04B35/5831 ,  C06B29/16 ,  B29C43/56 ,  C01B35/00

CPC分类号： C04B35/5831 ,  B01J3/08 ,  C06B29/16 ,  B01J2203/066

摘要： In order to produce a new substance having a diamond crystal structure, the following steps are taken in order. First, a graphite-like substance is prepared which contains boron (B), carbon (C) and nitrogen (N) as main elements. Then, the graphite-like substance is mixed with a metal powder to produce a mixture. Then, a pressure is applied to the mixture to produce a molded body, and then an explosion pressure is applied to the molded body.

摘要翻译： 为了制备具有金刚石晶体结构的新物质，按顺序进行以下步骤。 首先，制备含有硼（B），碳（C）和氮（N）作为主要元素的石墨状物质。 然后，将石墨状物质与金属粉末混合，制成混合物。 然后，向混合物施加压力以制造成型体，然后对成形体施加爆炸压力。