公开(公告)号：US12031913B2

公开(公告)日：2024-07-09

申请号：US15036181

申请日：2013-12-25

申请人： Hitachi, Ltd.

发明人： Takashi Anazawa ,  Takahide Yokoi ,  Yuichi Uchiho

IPC分类号： G01N21/64 ,  B01L3/00 ,  G01N21/03 ,  G01N21/05 ,  G01N27/447

CPC分类号： G01N21/6454 ,  B01L3/5027 ,  G01N21/6402 ,  G01N21/6452 ,  G01N27/447 ,  G01N27/44721 ,  G01N27/44726 ,  G01N27/44791 ,  B01L2300/0858 ,  B01L2300/0864 ,  G01N2021/0346 ,  G01N21/05 ,  G01N2201/06113

摘要： Efficient simultaneous laser-irradiation-fluorescence detection is performed for a plurality of channels of a microchip and simple and highly sensitive parallel analysis of a plurality of samples is enabled. In a microchip 1 made of an optically transparent solid material m1 with a refractive index n1, a plurality of channels 2 filled with a material m2 with a refractive index n2 and a plurality of channels 3 filled with a material m3 with a refractive index n3 are alternately arranged in parallel on the same plane. Here, m1, m2 and m3 are selected such that a relation of n2

公开(公告)号：US11162903B2

公开(公告)日：2021-11-02

申请号：US16740048

申请日：2020-01-10

申请人： HITACHI, LTD.

发明人： Shunsuke Kawabe ,  Yuichi Uchiho ,  Hideyuki Noda

IPC分类号： G01N21/76 ,  G01N35/02 ,  G01N21/11 ,  G01N35/10 ,  G01N21/64 ,  G01N33/58

摘要： An apparatus, system, and method for performing an efficient luminescence measurement are disclosed. The apparatus comprises a nozzle for dispensing a luminescent reagent into a well W in a microplate M, a luminescence measurement unit for measuring luminescence occurring in the well W caused by mixing of the luminescent reagent and a specimen, and a stage (moving unit) for moving the nozzle and the luminescence measurement unit together vertically and horizontally, wherein the nozzle is secured to the stage and the luminescence measurement unit is mounted to be movable vertically with respect to the stage through a holder and springs interposed between the luminescence measurement unit and the holder.