公开(公告)号：US20150182877A1

公开(公告)日：2015-07-02

申请号：US14416787

申请日：2013-07-25

Applicant: Hitachi High-Technologies Corporation

Inventor： Tadao Yabuhara ,  Izumi Waki

IPC: B01D15/38 ,  B01D15/20 ,  B01D15/42

CPC classification number: B01D15/3804 ,  B01D15/206 ,  B01D15/424 ,  B01L3/0275 ,  B01L2200/025 ,  B01L2200/0631 ,  B01L2200/0668 ,  B01L2300/0681 ,  G01N1/405 ,  G01N30/08 ,  G01N30/6091 ,  G01N35/025

Abstract: Provided is an analyzer performing solid-phase extraction of a measurement component (i.e., component to be measured) in a sample solution while decreasing an amount of waste generated and reducing a running cost. The analyzer includes: a solid-phase extraction container having a body part to receive a sample solution containing a measurement component of analytical target and a discharge passage to discharge the sample solution. Herein, the discharge passage is to be filled with a solid-phase extraction material for subjecting the measurement component to solid-phase extraction. The analyzer further includes a supplying mechanism for a solid-phase extraction material; a filter supplying mechanism; a determining mechanism for filling position; a discharging mechanism for discharging the filter and the solid-phase extraction material after the solid-phase extraction of the measurement component; and a container cleaning mechanism for cleaning the solid-phase extraction container from which the solid-phase extraction material is removed.

Abstract translation: 提供了一种在减少生成的废物量并降低运行成本的同时，在样品溶液中进行固相萃取测定成分（即待测部件）的分析装置。 分析装置包括：固相萃取容器，其具有容纳包含分析对象的测定成分的样品溶液的主体部分和排出样品溶液的排出通道。 这里，为了使测定成分进行固相萃取，用固相萃取材料填充排出通路。 分析装置还包括固相提取材料的供给机构; 过滤器供给机构; 填补职位的决定机制; 用于在固相萃取测量部件之后排出过滤器和固相萃取材料的排放机构; 以及用于清洗固相萃取物质从其中除去固相萃取物质的容器清洗机构。

公开(公告)号：US09597612B2

公开(公告)日：2017-03-21

申请号：US14416787

申请日：2013-07-25

Applicant: Hitachi High-Technologies Corporation

Inventor： Tadao Yabuhara ,  Izumi Waki

IPC: B01D15/38 ,  G01N1/40 ,  G01N35/02 ,  B01L3/02 ,  G01N30/08 ,  B01D15/20 ,  B01D15/42 ,  G01N30/60

CPC classification number: B01D15/3804 ,  B01D15/206 ,  B01D15/424 ,  B01L3/0275 ,  B01L2200/025 ,  B01L2200/0631 ,  B01L2200/0668 ,  B01L2300/0681 ,  G01N1/405 ,  G01N30/08 ,  G01N30/6091 ,  G01N35/025

Abstract: Provided is an analyzer performing solid-phase extraction of a measurement component (i.e., component to be measured) in a sample solution while decreasing an amount of waste generated and reducing a running cost. The analyzer includes: a solid-phase extraction container having a body part to receive a sample solution containing a measurement component of analytical target and a discharge passage to discharge the sample solution. Herein, the discharge passage is to be filled with a solid-phase extraction material for subjecting the measurement component to solid-phase extraction. The analyzer further includes a supplying mechanism for a solid-phase extraction material; a filter supplying mechanism; a determining mechanism for filling position; a discharging mechanism for discharging the filter and the solid-phase extraction material after the solid-phase extraction of the measurement component; and a container cleaning mechanism for cleaning the solid-phase extraction container from which the solid-phase extraction material is removed.

公开(公告)号：US10585089B2

公开(公告)日：2020-03-10

申请号：US15320406

申请日：2015-06-17

Applicant: HITACHI HIGH-TECHNOLOGIES CORPORATION

Inventor： Makoto Nogami ,  Shinya Ito ,  Tadao Yabuhara

IPC: G01N35/02 ,  G01N33/543 ,  G01N15/12 ,  G01N30/72 ,  G01N33/82 ,  G01N35/08 ,  G01N35/10 ,  G01N15/00

Abstract: When using an immunological analysis method wherein antigen-antibody reactions are used to form complexes of microparticles and a substance being measured, purifying, then measuring by spectroscopy, and a mass spectrometry method wherein antigen-antibody reactions are used to form complexes of microparticles and a substance being measured, purifying, then measuring with a mass spectrometer, the amount of the complex flowing in the flow path for immunological analysis and the amount of the complex flowing in the flow path for mass spectrometry are unknown, so the substance being measured cannot be accurately quantified even when merging information obtained from immunological analysis and information obtained from mass spectrometry. The invention provides a mechanism for quantifying the complexes after formation of the complexes, on the flow path for mass spectrometry and the flow path for immunological analysis.

公开(公告)号：US09885732B2

公开(公告)日：2018-02-06

申请号：US14911406

申请日：2014-06-24

Applicant: Hitachi High-Technologies Corporation

Inventor： Makoto Nogami ,  Shinya Ito ,  Tadao Yabuhara

IPC: G01N35/02 ,  G01N33/543 ,  G01N35/10 ,  G01N35/00 ,  G01N1/28 ,  G01N35/04

CPC classification number: G01N35/025 ,  G01N33/54366 ,  G01N35/00871 ,  G01N35/1065 ,  G01N2001/2826 ,  G01N2035/0458

Abstract: An analysis device is provided with a first disk on which a sample container and disposable container can be disposed, a second disk on which a solid-phase extraction cartridge and disposable container can be disposed, a first probe capable of transferring a sample of the sample container disposed on the first disk or a solution of the disposable container disposed on the first disk to the solid-phase extraction cartridge or disposable container disposed on the second disk, and a second probe capable of transferring a reagent of a reagent container to the sample container or disposable container disposed on the first disk and the solid-phase extraction cartridge or disposable container disposed on the second disk. Sample preprocessing before solid-phase extraction processing takes place on the first disk.

公开(公告)号：US11209197B2

公开(公告)日：2021-12-28

申请号：US16313521

申请日：2016-06-28

Applicant: Hitachi High-Technologies Corporation

Inventor： Tadao Yabuhara ,  Terumi Tamura ,  Hiroshi Watanabe

IPC: F25B21/02 ,  F25D11/02 ,  F25D23/12

Abstract: The present invention provides a refrigerating/heating device that efficiently refrigerates and heats while suppressing device costs. This refrigerating/heating device for efficiently heating and refrigerating is provided with: a refrigeration chamber; a Peltier-type cooler for supplying cold air to inside the refrigeration chamber; a heat radiation member for radiating Peltier heat; fans for air-cooling the heat radiation member; an exhaust duct through which waste heat from the fans and the heat radiation member passes; and an installation part to which a subject to be heated can be installed. The subject to be heated is installed in the waste heat flow path of the exhaust duct and heated.