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    METHODS AND APAPRATUS FOR MANUALLY SUSPENDING INTRATHORACIC IMPEDANCE FLUID STATUS MEASUREMENTS
    1.
    发明申请
    METHODS AND APAPRATUS FOR MANUALLY SUSPENDING INTRATHORACIC IMPEDANCE FLUID STATUS MEASUREMENTS 审中-公开
    用于手动停止静脉内阻滞流体状态测量的方法和APAPRATUS

    公开(公告)号：US20120303085A1

    公开(公告)日：2012-11-29

    申请号：US13570858

    申请日：2012-08-09

    申请人： Holly S. Vitense ,  Li Wang ,  Denise Dirnberger ,  Melissa M. Rhodes ,  Douglas A. Hettrick ,  Shantanu Sarkar

    发明人： Holly S. Vitense ,  Li Wang ,  Denise Dirnberger ,  Melissa M. Rhodes ,  Douglas A. Hettrick ,  Shantanu Sarkar

    IPC分类号： A61N1/365

    CPC分类号： A61N1/37258 ,  A61B5/0031 ,  A61B5/0215 ,  A61B5/053 ,  A61N1/37247 ,  G16H40/63

    摘要： The capability to suspend a patient alert relating to a monitored physiologic parameters addresses a need to selectively shut off a patient-alert signal or signals during the time a patient is being treated for an excursion in the parameter. Of course, in general a signal call attention to a patient's a potentially deleterious status or condition for which they should seek medical attention. Once a chronically-implanted monitoring device has detected or provided information about the parameter relative to a desired value, trend, or range and a clinician has been notified and intervened the alert signal is temporarily disabled for a predetermined period. That is, once the notification occurs and alert has served its purpose, the alert mechanism is selectively deactivated while the patient ostensibly begins to gradually correct the monitored physiologic parameter under a caregiver's direction and control. After which time, the alert will reactivate.

    摘要翻译： 暂停与所监测的生理参数相关的患者警报的能力解决了在患者被治疗参数期间偏移的时间期间选择性地切断病人警报信号或信号的需要。 当然，一般来说，一个信号会引起对患者的一个潜在的有害的状态或状况的关注，他们应该寻求医疗护理。 一旦长期植入的监测装置已经相对于期望值，趋势或范围已经检测或提供了关于参数的信息，并且已通知临床医生并且中介了警报信号暂时禁用预定时间段。 也就是说，一旦通知发生并且警报已经达到其目的，则警告机制被选择性地去激活，同时患者表面上开始逐渐校正受照顾者的方向和控制下的监测的生理参数。 之后，警报将重新启动。

    Methods and Apparatus for Manually Suspending Intrathoracic Impedance Fluid Status Measurements
    2.
    发明申请
    Methods and Apparatus for Manually Suspending Intrathoracic Impedance Fluid Status Measurements 有权
    手动悬挂胸膜内阻抗液体状态测量的方法和装置

    公开(公告)号：US20080103530A1

    公开(公告)日：2008-05-01

    申请号：US11554825

    申请日：2006-10-31

    申请人： Holly S. Vitense ,  Li Wang ,  Denise Dirnberger ,  Melissa M. Rhodes ,  Douglas A. Hettrick ,  Shantanu Sarkar

    发明人： Holly S. Vitense ,  Li Wang ,  Denise Dirnberger ,  Melissa M. Rhodes ,  Douglas A. Hettrick ,  Shantanu Sarkar

    IPC分类号： A61N1/00

    CPC分类号： A61N1/37258 ,  A61B5/0031 ,  A61B5/0215 ,  A61B5/053 ,  A61N1/37247 ,  G16H40/63

    摘要： The capability to suspend a patient alert relating to a monitored physiologic parameters addresses a need to selectively shut off a patient-alert signal or signals during the time a patient is being treated for an excursion in the parameter. Of course, in general a signal call attention to a patient's a potentially deleterious status or condition for which they should seek medical attention. Once a chronically-implanted monitoring device has detected or provided information about the parameter relative to a desired value, trend, or range and a clinician has been notified and intervened the alert signal is temporarily disabled for a predetermined period. That is, once the notification occurs and alert has served its purpose, the alert mechanism is selectively deactivated while the patient ostensibly begins to gradually correct the monitored physiologic parameter under a caregiver's direction and control. After which time, the alert will reactivate.

    摘要翻译： 暂停与所监测的生理参数相关的患者警报的能力解决了在患者被治疗参数期间偏移的时间期间选择性地切断病人警报信号或信号的需要。 当然，一般来说，一个信号会引起对患者的一个潜在的有害的状态或状况的关注，他们应该寻求医疗护理。 一旦长期植入的监测装置已经相对于期望值，趋势或范围已经检测或提供了关于参数的信息，并且已通知临床医生并且中介了警报信号暂时禁用预定时间段。 也就是说，一旦通知发生并且警报已经达到其目的，则警告机制被选择性地去激活，同时患者表面上开始逐渐校正受照顾者的方向和控制下的监测的生理参数。 之后，警报将重新启动。

    Methods and apparatus for manually suspending intrathoracic impedance fluid status measurements
    3.
    发明授权
    Methods and apparatus for manually suspending intrathoracic impedance fluid status measurements 有权
    手动暂停胸腔内阻抗流体状态测量的方法和装置

    公开(公告)号：US08948868B2

    公开(公告)日：2015-02-03

    申请号：US11554825

    申请日：2006-10-31

    申请人： Holly S. Vitense ,  Li Wang ,  Denise Dirnberger ,  Melissa M. Rhodes ,  Douglas A. Hettrick ,  Shantanu Sarkar

    发明人： Holly S. Vitense ,  Li Wang ,  Denise Dirnberger ,  Melissa M. Rhodes ,  Douglas A. Hettrick ,  Shantanu Sarkar

    IPC分类号： A61N1/00 ,  A61N1/372 ,  A61B5/00 ,  A61B5/0215 ,  A61B5/053

    CPC分类号： A61N1/37258 ,  A61B5/0031 ,  A61B5/0215 ,  A61B5/053 ,  A61N1/37247 ,  G16H40/63

    摘要： The capability to suspend a patient alert relating to a monitored physiologic parameters addresses a need to selectively shut off a patient-alert signal or signals during the time a patient is being treated for an excursion in the parameter. Of course, in general a signal call attention to a patient's a potentially deleterious status or condition for which they should seek medical attention. Once a chronically-implanted monitoring device has detected or provided information about the parameter relative to a desired value, trend, or range and a clinician has been notified and intervened the alert signal is temporarily disabled for a predetermined period. That is, once the notification occurs and alert has served its purpose, the alert mechanism is selectively deactivated while the patient ostensibly begins to gradually correct the monitored physiologic parameter under a caregiver's direction and control. After which time, the alert will reactivate.

    摘要翻译： 暂停与所监测的生理参数相关的患者警报的能力解决了在患者被治疗参数期间偏移的时间期间选择性地切断病人警报信号或信号的需要。 当然，一般来说，一个信号会引起对患者的一个潜在的有害的状态或状况的关注，他们应该寻求医疗护理。 一旦长期植入的监测装置已经相对于期望值，趋势或范围已经检测或提供了关于参数的信息，并且已通知临床医生并且中介了警报信号暂时禁用预定时间段。 也就是说，一旦通知发生并且警报已经达到其目的，则警告机制被选择性地去激活，同时患者表面上开始逐渐校正受照顾者的方向和控制下的监测的生理参数。 之后，警报将重新启动。

    Quantifying autonomic tone with thoracic impedance
    5.
    发明授权
    Quantifying autonomic tone with thoracic impedance 有权
    量化自主神经与胸阻抗

    公开(公告)号：US08435186B2

    公开(公告)日：2013-05-07

    申请号：US12696753

    申请日：2010-01-29

    申请人： Douglas A. Hettrick ,  Donald J. Hefner ,  Shantanu Sarkar ,  Todd M. Zielinski

    发明人： Douglas A. Hettrick ,  Donald J. Hefner ,  Shantanu Sarkar ,  Todd M. Zielinski

    IPC分类号： A61B5/00

    CPC分类号： A61N1/36521 ,  A61B5/0031 ,  A61B5/0215 ,  A61B5/02405 ,  A61B5/053 ,  A61B5/08 ,  A61B5/11 ,  A61B5/1116 ,  A61B5/4035 ,  A61N1/36535 ,  A61N1/37247 ,  A61N1/37258

    摘要： The disclosure describes techniques for quantifying the autonomic nervous system (ANS) health of a patient with thoracic impedance measurements. Thoracic impedance may be measured utilizing cardiac electrodes and an implantable medical device housing or other electrodes located on or within the patient. Since greater variability in thoracic impedance may indicate better health of the ANS, monitoring impedance changes in a patient may be used to quantify autonomic tone of the ANS, and ultimately, overall patient health. In some examples, thoracic impedance may be measured in response to a change in patient posture for acute monitoring or at predetermined times over several days, weeks, or months for more chronic monitoring of the patient. An implantable medical device may independently analyze the impedance measurements and transmit an alert to the patient or clinician when impedance changes indicate a change in patient health.

    摘要翻译： 本公开描述了用于量化具有胸部阻抗测量的患者的自主神经系统（ANS）健康的技术。 可以使用心电极和位于患者内部或内部的可植入医疗装置外壳或其它电极来测量胸腔阻抗。 由于胸部阻抗变化较大可能表明ANS的健康状况良好，所以监测患者的阻抗变化可用于量化ANS的自主音调，并最终对整体患者的健康状况进行量化。 在一些示例中，可以响应于用于急性监测的患者姿势的变化或在几天，几周或几个月的预定时间来测量胸部阻抗以进行更长期的患者监测。 当阻抗变化表示患者健康状况发生变化时，植入式医疗设备可以独立地分析阻抗测量结果并向患者或临床医生发送警报。

    HEART FAILURE MONITORING
    6.
    发明申请
    HEART FAILURE MONITORING 审中-公开
    心力衰竭监测

    公开(公告)号：US20120253207A1

    公开(公告)日：2012-10-04

    申请号：US13436408

    申请日：2012-03-30

    申请人： Shantanu Sarkar ,  Jodi L. Redemske ,  Eduardo N. Warman ,  Douglas A. Hettrick ,  Kevin T. Ousdigian

    发明人： Shantanu Sarkar ,  Jodi L. Redemske ,  Eduardo N. Warman ,  Douglas A. Hettrick ,  Kevin T. Ousdigian

    IPC分类号： A61B5/0205

    CPC分类号： A61B5/0006 ,  A61B5/0004 ,  A61B5/7275 ,  G06F19/3418 ,  G16H40/40 ,  G16H50/30

    摘要： Techniques for transmitting diagnostic information stored in an implantable medical device (IMD) based on patient hospitalization are described. For example, the IMD may transmit higher resolution diagnostic information to a clinician and/or an external device during a hospitalization period to aid the clinician in evaluating heart failure treatment and when discharge is proper. This higher resolution diagnostic information may include one or more patient metrics automatically generated and transmitted by the IMD at least once every two hours. During a post-hospitalization period, the IMD may transmit lower resolution diagnostic information to a clinician that indicates a risk level of re-hospitalization. The lower resolution diagnostic information may include the risk level and/or patient metrics once a day, for example. In this manner, the IMD transmitted diagnostic information may be tailored to the specific heart failure monitoring needed by the patient.

    摘要翻译： 描述了基于患者住院时间传送存储在可植入医疗装置（IMD）中的诊断信息的技术。 例如，IMD可以在住院期间向临床医师和/或外部设备传送更高分辨率的诊断信息，以帮助临床医师评价心力衰竭治疗以及放电是否合适。 该更高分辨率的诊断信息可以包括由IMD自动生成和发送的至少每两小时一次的一个或多个患者度量。 在住院后期间，IMD可以向临床医生传递较低分辨率的诊断信息，指示重新住院的风险水平。 例如，较低分辨率诊断信息可以包括一天一次的风险水平和/或患者度量。 以这种方式，IMD传输的诊断信息可以针对患者所需的特定心力衰竭监测。

    ESTIMATING CARDIOVASCULAR PRESSURE AND VOLUME USING IMPEDANCE MEASUREMENTS
    8.
    发明申请
    ESTIMATING CARDIOVASCULAR PRESSURE AND VOLUME USING IMPEDANCE MEASUREMENTS 有权
    使用阻力测量估算心血管压力和体积

    公开(公告)号：US20100030087A1

    公开(公告)日：2010-02-04

    申请号：US12263065

    申请日：2008-10-31

    申请人： Douglas A. Hettrick ,  Yong K. Cho ,  Mattias Rouw ,  Shantanu Sarkar ,  Todd M. Zielinski

    发明人： Douglas A. Hettrick ,  Yong K. Cho ,  Mattias Rouw ,  Shantanu Sarkar ,  Todd M. Zielinski

    IPC分类号： A61B5/0215 ,  A61B5/053

    CPC分类号： A61N1/36521 ,  A61B5/021 ,  A61B5/0215 ,  A61B5/02158 ,  A61B5/053 ,  A61B5/0535 ,  A61B5/0538 ,  A61B5/7239 ,  A61N1/36564

    摘要： Techniques for estimating a cardiac chamber or vascular pressure based upon impedance are described. A device or system may measure an impedance between at least two electrodes implanted within or proximate to a cardiovascular system. The device or system may estimate a pressure of an element of the cardiovascular system based on a relationship between impedance and volume of the element, and based on a empirical relationship between the volume and the pressure. The device or system may also estimate the dimension of the element based on the impedance-volume relationship, or other characteristics based on the impedance. Because the impedance measurements may be obtained, in some examples, by using electrodes and leads implanted within the cardiovascular system and coupled to an implantable medical device, a practical estimation of a cardiovascular pressure can be obtained on a chronic basis without requiring the use other invasive sensors, such as micronanometer transducers.

    摘要翻译： 描述了基于阻抗估计心室或血管压力的技术。 装置或系统可以测量植入在心血管系统内或其附近的至少两个电极之间的阻抗。 装置或系统可以基于元件的阻抗和体积之间的关系，并且基于体积和压力之间的经验关系来估计心血管系统的元件的压力。 装置或系统还可以基于阻抗 - 体积关系或基于阻抗的其它特性来估计元件的尺寸。 由于可以获得阻抗测量值，在一些示例中，通过使用植入心血管系统内并连接到可植入医疗装置的电极和引线，可以长期获得心血管压力的实际估计，而不需要使用其它侵入性 传感器，如微量计传感器。