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公开(公告)号：US09198608B2
公开(公告)日：2015-12-01
申请号：US13304274
申请日：2011-11-23
申请人： Hooman Hafezi , David O'Reilly , Patricia Johnson , Zahedeh Hatamkhany , Timothy Robertson , Mark Zdeblick
发明人： Hooman Hafezi , David O'Reilly , Patricia Johnson , Zahedeh Hatamkhany , Timothy Robertson , Mark Zdeblick
IPC分类号： G08B13/14 , A61B5/145 , A61B5/07 , A61J3/00 , H01Q1/27 , A61B5/01 , A61B5/03 , A61B5/1473 , A61B5/00 , H04B1/3888 , H04B1/38
CPC分类号： G08B21/18 , A61B5/01 , A61B5/036 , A61B5/073 , A61B5/14539 , A61B5/1473 , A61B5/4839 , A61B2562/0214 , A61J3/007 , B65D41/02 , H01Q1/273 , H04B1/3888 , H04B2001/3894
摘要： The system of the present invention includes a container and an electronic component with a partial power source in the form of dissimilar materials. The container includes a liquid. Upon contact with the liquid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature.
摘要翻译： 本发明的系统包括容器和具有不同材料形式的部分动力源的电子部件。 容器包括液体。 当与液体接触时，产生电压电位并且电源完成，这激活了系统。 电子部件控制不同材料之间的电导，以产生独特的当前签名。
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公开(公告)号：US08836513B2
公开(公告)日：2014-09-16
申请号：US13180507
申请日：2011-07-11
CPC分类号： A61B5/073 , A61B5/14539 , A61B5/1473 , A61B5/4839 , A61B5/6801 , A61B5/6861 , A61J3/007 , H01Q1/273
摘要： The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can also be associated with food and communicate data about ingestion of food material to a receiver.
摘要翻译： 本发明的系统包括不同材料形式的导电元件，电子元件和部分电源。 当与导电流体接触时，产生电压电位并且电源完成，这激活了系统。 电子部件控制不同材料之间的电导，以产生独特的当前签名。 该系统还可以与食物相关联，并将关于摄取食物材料的数据传达给接收器。
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公开(公告)号：US20120299723A1
公开(公告)日：2012-11-29
申请号：US13304274
申请日：2011-11-23
申请人： Hooman Hafezi , David O'Reilly , Patricia Johnson , Zahedeh Hatamkhany , Timothy Robertson , Mark Zdeblick
发明人： Hooman Hafezi , David O'Reilly , Patricia Johnson , Zahedeh Hatamkhany , Timothy Robertson , Mark Zdeblick
IPC分类号： G08B1/08
CPC分类号： G08B21/18 , A61B5/01 , A61B5/036 , A61B5/073 , A61B5/14539 , A61B5/1473 , A61B5/4839 , A61B2562/0214 , A61J3/007 , B65D41/02 , H01Q1/273 , H04B1/3888 , H04B2001/3894
摘要： The system of the present invention includes a container and an electronic component with a partial power source in the form of dissimilar materials. The container includes a liquid. Upon contact with the liquid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature.
摘要翻译： 本发明的系统包括容器和具有不同材料形式的部分动力源的电子部件。 容器包括液体。 当与液体接触时，产生电压电位并且电源完成，这激活了系统。 电子部件控制不同材料之间的电导，以产生独特的当前签名。
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公开(公告)号：US20120062379A1
公开(公告)日：2012-03-15
申请号：US13180507
申请日：2011-07-11
IPC分类号： G08B1/08
CPC分类号： A61B5/073 , A61B5/14539 , A61B5/1473 , A61B5/4839 , A61B5/6801 , A61B5/6861 , A61J3/007 , H01Q1/273
摘要： The system of the present invention includes a conductive element, an electronic component, and a partial power source in the form of dissimilar materials. Upon contact with a conducting fluid, a voltage potential is created and the power source is completed, which activates the system. The electronic component controls the conductance between the dissimilar materials to produce a unique current signature. The system can also be associated with food and communicate data about ingestion of food material to a receiver.
摘要翻译： 本发明的系统包括不同材料形式的导电元件，电子元件和部分电源。 当与导电流体接触时，产生电压电位并且电源完成，这激活了系统。 电子部件控制不同材料之间的电导，以产生独特的当前签名。 该系统还可以与食物相关联，并将关于摄取食物材料的数据传达给接收器。
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公开(公告)号：US06346270B1
公开(公告)日：2002-02-12
申请号：US09587686
申请日：2000-06-05
IPC分类号： A61K924
CPC分类号： A61K9/0004 , A61K31/4166
摘要： A therapeutic composition, a dosage form and a method are disclosed for administering phenytoin indicated for the management of epilepsy.
摘要翻译： 公开了治疗组合物，剂型和方法，用于施用用于治疗癫痫的苯妥英。
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公开(公告)号：US09029416B2
公开(公告)日：2015-05-12
申请号：US10638977
申请日：2003-08-12
申请人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Zahedeh Hatamkhany , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Richard G. Weyers
发明人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Zahedeh Hatamkhany , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Richard G. Weyers
IPC分类号： A61K9/20 , A61K9/00 , A61K9/24 , A61K9/50 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458
CPC分类号： A61K9/2086 , A61K9/0002 , A61K9/0004 , A61K9/2072 , A61K9/209 , A61K9/5084 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458
摘要： Methods and devices for maintaining a desired therapeutic drug effect over a prolonged therapy period are provided. In particular, oral dosage forms that release drug within the gastrointestinal tract at an ascending release rate over an extended time period are provided. The dosage forms may additionally comprise an immediate-release dose of drug.
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公开(公告)号：US06930129B2
公开(公告)日：2005-08-16
申请号：US09802709
申请日：2001-03-08
申请人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Zahedeh Hatamkhany , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Richard G. Weyers
发明人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Zahedeh Hatamkhany , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Richard G. Weyers
IPC分类号： A61K9/00 , A61K9/20 , A61K9/24 , A61K9/50 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458 , A61K31/235
CPC分类号： A61K9/2086 , A61K9/0002 , A61K9/0004 , A61K9/2072 , A61K9/209 , A61K9/5084 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458
摘要： Methods and devices for maintaining a desired therapeutic drug effect over a prolonged therapy period are provided. In particular, oral dosage forms that release drug within the gastrointestinal tract at an ascending release rate over an extended time period are provided. The dosage forms may additionally comprise an immediate-release dose of drug.
摘要翻译： 提供了用于在延长的治疗期间维持期望的治疗药物作用的方法和装置。 特别地，提供了在延长的时间段内以升高释放速率在胃肠道内释放药物的口服剂型。 剂型还可包含立即释放剂量的药物。
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公开(公告)号：US20050238709A1
公开(公告)日：2005-10-27
申请号：US10639914
申请日：2003-08-12
申请人： Andrew Lam , Padmaja Shivanand , Atul Ayer , Zahedeh Hatamkhany , Suneel Gupta , Diane Guinta , Carol Christopher , Samuel Saks , Lawrence Hamel , Jeri Wright , Richard Weyers
发明人： Andrew Lam , Padmaja Shivanand , Atul Ayer , Zahedeh Hatamkhany , Suneel Gupta , Diane Guinta , Carol Christopher , Samuel Saks , Lawrence Hamel , Jeri Wright , Richard Weyers
IPC分类号： A61K9/00 , A61K9/20 , A61K9/24 , A61K9/50 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458 , A61K31/445
CPC分类号： A61K9/2086 , A61K9/0002 , A61K9/0004 , A61K9/2072 , A61K9/209 , A61K9/5084 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458
摘要： Methods and devices for maintaining a desired therapeutic drug effect over a prolonged therapy period are provided. In particular, oral dosage forms that release drug within the gastrointestinal tract at an ascending release rate over an extended time period are provided. The dosage forms may additionally comprise an immediate-release dose of drug.
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公开(公告)号：US06919373B1
公开(公告)日：2005-07-19
申请号：US09253317
申请日：1999-02-19
申请人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Richard G. Weyers , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Zahedeh Hatamkhany
发明人： Andrew C. Lam , Padmaja Shivanand , Atul D. Ayer , Richard G. Weyers , Suneel K. Gupta , Diane R. Guinta , Carol A. Christopher , Samuel R. Saks , Lawrence G. Hamel , Jeri D. Wright , Zahedeh Hatamkhany
IPC分类号： A61K9/00 , A61K9/20 , A61K9/24 , A61K9/50 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458 , A61K31/235
CPC分类号： A61K9/2086 , A61K9/0002 , A61K9/0004 , A61K9/2072 , A61K9/209 , A61K9/5084 , A61K9/70 , A61K31/00 , A61K31/137 , A61K31/421 , A61K31/4422 , A61K31/4458
摘要： Methods and devices for maintaining a desired therapeutic drug effect over a prolonged therapy period are provided. In particular, oral dosage forms that release drug within the gastrointestinal tract at an ascending release rate over an extended time period are provided. The dosage forms may additionally comprise an immediate-release dose of drug.
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公开(公告)号：US20050112190A1
公开(公告)日：2005-05-26
申请号：US10950301
申请日：2004-09-23
申请人： Lauren Wiser , Betty Yu , Kimberly Capell , Andrew Lam , Zahedeh Hatamkhany
发明人： Lauren Wiser , Betty Yu , Kimberly Capell , Andrew Lam , Zahedeh Hatamkhany
IPC分类号： A61K9/00 , A61K31/167 , A61L15/16 , A61K9/22 , A61K9/48
CPC分类号： A61K31/167 , A61K9/0004
摘要： The present invention is directed to a dosage form configured to provide the controlled release of an active agent formulation. A dosage form according to the present invention includes a reservoir containing an active agent formulation and an engine positioned at least partially within the reservoir. In order to reduce the possibility that the engine included in a dosage form of the present invention will separate from the reservoir either during or after fabrication of the dosage form of the present invention, the engine included in a dosage form according to the present invention is bonded to an inside surface of the reservoir. The present invention also includes methods for preparing a controlled release dosage form.
摘要翻译： 本发明涉及配制成提供活性剂制剂的受控释放的剂型。 根据本发明的剂型包括含有活性剂制剂的储存器和至少部分地位于储存器内的发动机。 为了减少包含在本发明的剂型中的发动机在本发明的剂型的制造期间或之后与储存器分离的可能性，包括在根据本发明的剂型中的发动机是 结合到储存器的内表面。 本发明还包括制备控释剂型的方法。
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