公开(公告)号：US20240110234A1

公开(公告)日：2024-04-04

申请号：US18475939

申请日：2023-09-27

Applicant: Illumina, Inc.

Inventor： Justin Robbins ,  Marie Hu

IPC: C12Q1/6844 ,  C12Q1/6874

CPC classification number: C12Q1/6844 ,  C12Q1/6874

Abstract: This disclosure relates to novel amplification compositions and methods, in particular for use in sequencing.

公开(公告)号：US20240124914A1

公开(公告)日：2024-04-18

申请号：US18476015

申请日：2023-09-27

Applicant: Illumina, Inc.

Inventor： Justin Robbins

IPC: C12Q1/48 ,  C12Q1/6844 ,  C12Q1/6869

CPC classification number: C12Q1/485 ,  C12Q1/6844 ,  C12Q1/6869

Abstract: This disclosure relates to novel thermophilic amplification compositions and methods, in particular for use in nucleic acid amplification and sequencing.

公开(公告)号：US20240102067A1

公开(公告)日：2024-03-28

申请号：US18473971

申请日：2023-09-25

Applicant: Illumina, Inc.

Inventor： Kay Klausing ,  Jonathan Boutell ,  Trina Osothprarop ,  Oliver Miller ,  Justin Robbins

IPC: C12P19/34 ,  C12Q1/6874

CPC classification number: C12P19/34 ,  C12Q1/6874

Abstract: This disclosure relates to novel mjresynthesis kits and methods, in particular for use in pairwise sequencing.

公开(公告)号：US20240132956A1

公开(公告)日：2024-04-25

申请号：US18476151

申请日：2023-09-27

Applicant: ILLUMINA, INC.

Inventor： Justin Robbins ,  Mathieu Lessard-Viger

IPC: C12Q1/6874 ,  B01L3/00

CPC classification number: C12Q1/6874 ,  B01L3/502761 ,  B01L2200/0647 ,  B01L2200/12 ,  B01L2300/0896 ,  B01L2300/12

Abstract: An example of a nucleic acid sequencing component includes a support. A glycolipid bi-layer is attached to at least a portion of the support. First and second primers are respectively attached to the glycolipid bi-layer. In one example, the support is a substrate of a flow cell. In another example, the support is a core nanostructure that can be introduced into a flow cell.

公开(公告)号：US20240124929A1

公开(公告)日：2024-04-18

申请号：US18476031

申请日：2023-09-27

Applicant: Illumina, Inc.

Inventor： Justin Robbins

IPC: C12Q1/6869 ,  C12Q1/6844

CPC classification number: C12Q1/6869 ,  C12Q1/6844 ,  C12Q1/6806

Abstract: This disclosure relates to novel amplification compositions and methods, in particular for use in nucleic acid amplification and sequencing, preferably that do not involve reagents that are thermophilic.

公开(公告)号：US20240110221A1

公开(公告)日：2024-04-04

申请号：US18476052

申请日：2023-09-27

Applicant: Illumina, Inc.

Inventor： Justin Robbins

IPC: C12Q1/34 ,  C12Q1/6844 ,  C12Q1/6869

CPC classification number: C12Q1/34 ,  C12Q1/6844 ,  C12Q1/6869

Abstract: This disclosure relates to novel amplification compositions and methods, in particular for use in sequencing.

公开(公告)号：US20230212667A1

公开(公告)日：2023-07-06

申请号：US18089867

申请日：2022-12-28

Applicant: ILLUMINA CAMBRIDGE LIMITED ,  ILLUMINA, INC.

Inventor： Jonathan Mark Boutell ,  Eli M. Carrami ,  Pietro Gatti Lafranconi ,  Philip Balding ,  Oliver Jon Miller ,  Kay Klausing ,  Justin Robbins ,  Xiaolin Wu

IPC: C12Q1/6874

CPC classification number: C12Q1/6874 ,  C12Q1/6806

Abstract: Polynucleotide sequencing methods for sequencing one or more polynucleotide templates use primers bound to a surface as sequencing primers. The surface primers may include at least a portion of a surface oligonucleotide used during cluster formation. The sequencing methods may be used for single stranded sequencing or double stranded sequencing. Double stranded sequencing methods may employ an enzyme that has nick-translation activity. A kit includes all the reagents needed for sequencing does not include sequencing primers. The kit may be used to accomplish the sequencing methods of the present disclosure.