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    Capillary flow plasmonic sensor
    1.
    发明授权
    Capillary flow plasmonic sensor 有权

    公开(公告)号：US09678014B2

    公开(公告)日：2017-06-13

    申请号：US14554429

    申请日：2014-11-26

    Applicant: IMEC VZW

    Inventor： Chengjun Huang ,  Liesbet Lagae

    IPC: G01N21/65 ,  G01N33/543 ,  G01N21/552 ,  B01L3/00

    CPC classification number: G01N21/658 ,  B01L3/50273 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/0406 ,  B01L2400/086 ,  G01N21/554 ,  G01N33/54306 ,  G01N33/54386

    Abstract: In a first aspect, a micro-fluidic device is presented, comprising: a micro-fluidic channel having an inner surface; a sensing region inside the micro-fluidic channel configured for adsorbing at least one analyte, the sensing region comprising a plurality of pillars positioned along the length of the inner surface of the micro-fluidic channel wherein the plurality of pillars are configured for creating an electromagnetic field localization thereby making the sensing region suitable for sensing plasmonic or surface enhanced Raman signals when irradiated; characterized in that: the plurality of pillars are further configured for creating a capillary action in the micro-fluidic channel when a fluid sample is present in the micro-fluidic channel. In a second aspect, a multiplexed plasmonic microchip for detecting at least one analyte in a fluid sample is presented, comprising: a plurality of micro-fluidic devices as presented in the first aspect; a supply system for providing the fluid sample to the plurality of micro-fluidic devices. Further, a method for detecting analytes is presented using a device according the first or second aspect.

    Capillary flow plasmonic sensor
    3.
    发明申请
    Capillary flow plasmonic sensor 有权
    毛细管流动等离子体传感器

    公开(公告)号：US20150153283A1

    公开(公告)日：2015-06-04

    申请号：US14554429

    申请日：2014-11-26

    Applicant: IMEC VZW

    Inventor： Chengjun Huang ,  Liesbet Lagae

    IPC: G01N21/65 ,  G01N33/543

    CPC classification number: G01N21/658 ,  B01L3/50273 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/0406 ,  B01L2400/086 ,  G01N21/554 ,  G01N33/54306 ,  G01N33/54386

    Abstract: In a first aspect, a micro-fluidic device is presented, comprising: a micro-fluidic channel having an inner surface; a sensing region inside the micro-fluidic channel configured for adsorbing at least one analyte, the sensing region comprising a plurality of pillars positioned along the length of the inner surface of the micro-fluidic channel wherein the plurality of pillars are configured for creating an electromagnetic field localization thereby making the sensing region suitable for sensing plasmonic or surface enhanced Raman signals when irradiated; characterized in that: the plurality of pillars are further configured for creating a capillary action in the micro-fluidic channel when a fluid sample is present in the micro-fluidic channel. In a second aspect, a multiplexed plasmonic microchip for detecting at least one analyte in a fluid sample is presented, comprising: a plurality of micro-fluidic devices as presented in the first aspect; a supply system for providing the fluid sample to the plurality of micro-fluidic devices. Further, a method for detecting analytes is presented using a device according the first or second aspect.

    Abstract translation: 在第一方面，提出一种微流体装置，包括：具有内表面的微流体通道; 所述微流体通道内部的感测区域被配置用于吸附至少一种分析物，所述感测区域包括沿着所述微流体通道的内表面的长度定位的多个柱，其中所述多个柱被配置用于产生电磁 场定位，从而使得感测区域适合于在照射时感测等离子体激元或表面增强拉曼信号; 其特征在于：所述多个支柱进一步构造成当所述微流体通道中存在流体样品时在所述微流体通道中产生毛细管作用。 在第二方面，提供了一种用于检测流体样品中的至少一种分析物的复合等离子体微芯片，包括：如第一方面所述的多个微流体装置; 用于将流体样品提供给多个微流体装置的供应系统。 此外，使用根据第一或第二方面的装置来呈现用于检测分析物的方法。

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