公开(公告)号：US20030116877A1

公开(公告)日：2003-06-26

申请号：US10241440

申请日：2002-09-12

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Chun-Jen Liao ,  Yu-Ju Lin ,  Chin-Fu Chen ,  Ken-Yuan Chang

IPC: B29C067/20

CPC classification number: C08J9/26 ,  B29C67/202 ,  C08J2201/042 ,  C08J2201/044 ,  C08J2201/0464

Abstract: A process for producing porous polymer material. The method combines a polymer and water-soluble granules to form a mixture. The mixture is placed into a mold; the surface of the polymer is dissolved to cause cohesion and form a polymer structure having water-soluble granules dispersed within, and water is introduced into the inner part of the polymer structure so that the polymer is solidified and water-soluble granules are washed out to obtain a porous polymer material. According to the invention, single or multiple layers of porous polymer material with different apertures, porosities, or made with different materials, are obtained by combining different polymer materials and water-soluble granules having different particle sizes in different weight ratios.

Abstract translation: 一种多孔聚合物材料的制造方法。 该方法结合聚合物和水溶性颗粒以形成混合物。 将混合物放入模具中; 溶解聚合物的表面以引起内聚，并形成分散在其中的水溶性颗粒的聚合物结构，并且将水引入聚合物结构的内部，使得聚合物固化并将水溶性颗粒冲洗至 获得多孔聚合物材料。 根据本发明，通过将不同聚合物材料和具有不同重量比的不同粒度的水溶性颗粒结合，获得具有不同孔径，孔隙率或不同材料制成的单层或多层多孔聚合物材料。

公开(公告)号：US20040121459A1

公开(公告)日：2004-06-24

申请号：US10620339

申请日：2003-07-17

Applicant: Industrial Technology Research Institute

Inventor： Chun-Jen Liao ,  Yu-Ju Lin ,  Chin-Fu Chen

IPC: C12N005/08

CPC classification number: A61L27/3847 ,  A61L27/56 ,  C12N5/0068 ,  C12N2533/40

Abstract: The present invention provides method and carrier for culturing multi-layered tissue in vitro, wherein few amounts of tissue blocks and cells are positioned within a porous multi-layer carrier consisting of a cavity structure. By taking advantage of the structure of the carrier, tissue blocks and cells are separated into different layers according to their sizes, and incubated in vitro to reconstruct a multi-layered tissue for tissue repair.

Abstract translation: 本发明提供体外培养多层组织的方法和载体，其中少量的组织块和细胞位于由空腔结构构成的多孔多层载体内。 通过利用载体的结构，将组织块和细胞根据其大小分成不同的层，并在体外温育以重建用于组织修复的多层组织。

公开(公告)号：US20020086977A1

公开(公告)日：2002-07-04

申请号：US10083242

申请日：2001-10-19

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Huey-Min Lai ,  Chun-Hui Chang ,  Chun-Jen Liao ,  Chin-Fu Chen ,  Kuei-Hung Wu ,  Yuan-Chia Chang ,  Yu-Yen Jan ,  Tsung-Yi Mou

IPC: A61K035/14 ,  C07K016/00 ,  C09H001/00 ,  A61K038/17 ,  C07K017/00 ,  C07K014/00 ,  C07K001/00 ,  A61K038/00 ,  A61K038/16

CPC classification number: C08L5/08 ,  C07K17/08 ,  C08B37/003 ,  C08H1/06 ,  C08J9/26 ,  C08J2201/0462 ,  C08L89/06 ,  C08L2666/02

Abstract: The present invention discloses a method for preparing a hydrophilic porous polymeric material comprising the step of mixing a hydrophilic polymeric material with a hydrophobic material; solvent sintering the surface of the hydrophilic polymeric material with water or an aqueous solution; and removing the hydrophobic material contained within the hydrophilic polymeric material with a massive organic solvent. Thus, the hydrophilic porous polymeric material with high porosity and stable structure is rapidly mass produced.

Abstract translation: 本发明公开了一种制备亲水性多孔聚合材料的方法，包括将亲水聚合物与疏水性材料混合的步骤; 溶剂用水或水溶液烧结亲水性聚合物材料的表面; 并用大量有机溶剂除去亲水性聚合物材料中所含的疏水材料。 因此，快速大量生产具有高孔隙率和稳定结构的亲水性多孔聚合材料。

公开(公告)号：US20020022673A1

公开(公告)日：2002-02-21

申请号：US09870370

申请日：2001-05-30

Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE

Inventor： Chun-Jen Liao ,  Chin-Fu Chen ,  Jui-Hsiang Chen ,  Ken-Yuan Chang ,  Yure-Ru Lin ,  Shu-Fang Chiang

IPC: C08J009/26

CPC classification number: C08J9/26 ,  C08J2201/0444 ,  C08J2201/046 ,  C08J2201/0542

Abstract: The present invention provides a process for producing porous polymer materials. In the present invention, a polymer material and a soluble material are mixed in their solid states. The surface of the polymer material is partially dissolved and fused by introducing a solvent. The present invention makes use of a pressure difference while introducing a non-solvent into the polymer material to solidify and resolve the solved polymer material. Then, a substantial amount of water is used to wash the inside soluble material out. Therefore, the porous polymer materials with high porosity and interconnecting pores inside the materials are produced massively and rapidly.