公开(公告)号：US20180055643A1

公开(公告)日：2018-03-01

申请号：US15671048

申请日：2017-08-07

Applicant: Nanochon, LLC

Inventor： Nathan Jonathan Castro ,  Benjamin Blair Holmes

IPC: A61F2/30 ,  A61L27/18 ,  A61L27/56 ,  C08J9/26 ,  C08J9/00 ,  A61L27/12 ,  B29C64/30 ,  B33Y10/00 ,  B33Y80/00

CPC classification number: A61F2/30942 ,  A61F2/28 ,  A61F2/30756 ,  A61F2/30771 ,  A61F2002/2835 ,  A61F2002/30766 ,  A61F2002/30784 ,  A61F2002/30838 ,  A61F2002/3084 ,  A61F2002/3092 ,  A61F2002/3093 ,  A61F2002/30948 ,  A61F2002/30962 ,  A61F2002/30968 ,  A61F2002/3097 ,  A61F2002/30971 ,  A61F2002/30985 ,  A61L27/12 ,  A61L27/18 ,  A61L27/48 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  A61L2400/08 ,  A61L2400/12 ,  A61L2430/02 ,  A61L2430/06 ,  B29C64/118 ,  B29C64/30 ,  B29K2071/02 ,  B29K2075/00 ,  B29K2995/0056 ,  B29L2031/7532 ,  B33Y10/00 ,  B33Y80/00 ,  C08J9/0061 ,  C08J9/0071 ,  C08J9/26 ,  C08J2201/0464 ,  C08J2205/04 ,  C08J2205/042 ,  C08J2205/044 ,  C08J2205/06 ,  C08J2207/10 ,  C08J2325/06 ,  C08J2367/04 ,  C08J2375/04 ,  C08J2405/04 ,  C08J2429/04 ,  C08J2471/02 ,  C08J2489/00 ,  C08L75/04 ,  C08L67/04

Abstract: The present disclosure relates to a three-dimensionally (3D) printed tissue engineering scaffold for tissue regeneration and a method for manufacturing the 3D printed tissue engineering scaffold. The 3D printed tissue engineering scaffold may be fabricated at least in part from a composite material having an insoluble component and soluble component. The three-dimensional tissue scaffolds of the disclosure may be fabricated via a rapid prototyping machine. In some instances, the three-dimensional shape of the fabricated tissue engineering scaffold may correspond to a three-dimensional shape of a tissue defect of a patient.

公开(公告)号：US09676914B2

公开(公告)日：2017-06-13

申请号：US14651764

申请日：2013-12-23

Applicant: Fondazione Istituto Italiano de Tecnologia

Inventor： Despina Fragouli ,  Elisa Mele ,  Athanasia Athanasiou

IPC: C08J9/26 ,  C08J9/36 ,  C08J9/00 ,  A61L27/48 ,  A61L27/56

CPC classification number: C08J9/26 ,  A61L27/48 ,  A61L27/56 ,  A61L2400/08 ,  C08J9/0061 ,  C08J9/36 ,  C08J2201/046 ,  C08J2201/0464 ,  C08J2205/022 ,  C08J2205/05 ,  C08J2333/06 ,  C08J2375/04 ,  C08J2383/04 ,  C08J2389/00 ,  C08J2400/14 ,  C08J2401/02 ,  C08J2405/04 ,  C08J2405/08 ,  C08J2431/04 ,  C08J2433/26 ,  C08J2477/06

Abstract: Process for the production of a polymer foam with use of hydrogel pearls as porosity generating template, comprising the steps of:—providing a matrix of polymer or prepolymer in viscous state including, as a dispersed phase, hydrogel pearls, where said pearls are dispersed in said matrix so as to generate intercommunicating cells,—causing the solidification of the matrix of polymer or prepolymer to obtain said polymer foam including said hydrogel pearls, characterised in that it comprises the operation of subjecting the thus obtained foam to conditions which cause the dehydration of said hydrogel pearls so as to obtain a reduction of volume of said pearls and—removing the dehydrated pearls by immersion in water of the polymer foam or by exposure of the foam to a flow of pressurized gas or water.

公开(公告)号：US08946352B2

公开(公告)日：2015-02-03

申请号：US13128207

申请日：2010-12-16

Applicant: Carlos A. Cruz

Inventor： Carlos A. Cruz

IPC: C08L29/04 ,  C08J9/26 ,  B01D67/00 ,  B01D71/26 ,  B01D71/34 ,  B01D71/38 ,  B01D71/40 ,  B01D71/48 ,  C08J9/00 ,  C08L77/00

CPC classification number: B01D67/0093 ,  B01D67/0006 ,  B01D67/002 ,  B01D67/003 ,  B01D67/0088 ,  B01D71/26 ,  B01D71/34 ,  B01D71/38 ,  B01D71/40 ,  B01D71/48 ,  B01D2323/30 ,  B01D2323/34 ,  B01D2323/42 ,  B01D2323/50 ,  B29C47/0004 ,  B29C47/0057 ,  B29D7/01 ,  B29K2029/04 ,  B29K2033/04 ,  B29K2033/12 ,  B29K2101/12 ,  B29K2105/0038 ,  B29K2105/0088 ,  B29K2105/24 ,  B29L2031/755 ,  C08J9/0061 ,  C08J9/26 ,  C08J2201/03 ,  C08J2201/0464 ,  C08J2333/10 ,  C08J2351/00 ,  C08J2429/04 ,  C08L21/00 ,  C08L23/06 ,  C08L23/12 ,  C08L27/16 ,  C08L29/04 ,  C08L33/14 ,  C08L67/00 ,  C08L77/00 ,  G05B15/02

Abstract: Technologies and implementations for providing melt processable poly(vinyl alcohol) blends and poly(vinyl alcohol) based membranes are generally disclosed.

Abstract translation: 通常公开了用于提供可熔融加工的聚（乙烯醇）共混物和基于聚（乙烯醇））的膜的技术和实施方案。

公开(公告)号：US20130248442A1

公开(公告)日：2013-09-26

申请号：US13991695

申请日：2011-12-05

Applicant: Noriaki Harada ,  Yoshihide Kawaguchi ,  Atsushi Hiro ,  Atsuko Mizuike ,  Osamu Hayashi ,  Katsumi Ishii ,  Chiaki Harada

Inventor： Noriaki Harada ,  Yoshihide Kawaguchi ,  Atsushi Hiro ,  Atsuko Mizuike ,  Osamu Hayashi ,  Katsumi Ishii ,  Chiaki Harada

IPC: B01D67/00

CPC classification number: B01D67/003 ,  B01D71/46 ,  B01D2323/18 ,  C08J9/286 ,  C08J2201/026 ,  C08J2201/0464 ,  C08J2363/02 ,  C08L63/00

Abstract: Provided is a porous epoxy resin sheet produced by cutting a cured epoxy resin body to a predetermined thickness, the porous epoxy resin sheet having a large surface area and a uniform in-plane pore size distribution. A method for producing a porous epoxy resin sheet, comprising forming a cylindrical or columnar cured resin body from a resin mixture containing an epoxy resin, a curing agent, and a porogen, cutting the surface of the cured resin body at a predetermined thickness to make an epoxy resin sheet, and then removing the porogen from the sheet to render the sheet porous, wherein when the cured resin body is formed from the resin mixture, curing is performed in a state where the viscosity of the mixture is at least 1,000 mPa·s.

Abstract translation: 本发明提供一种通过将固化的环氧树脂体切割成预定厚度而生产的多孔环氧树脂片，具有大的表面积和均匀的面内孔径分布的多孔环氧树脂片。 一种多孔环氧树脂片的制造方法，其特征在于，包括由含有环氧树脂，固化剂，致孔剂的树脂混合物形成圆筒状或柱状的固化树脂体，将树脂固化体的表面切割成规定的厚度， 环氧树脂片，然后从片材中除去致孔剂以使片材多孔，其中当由树脂混合物形成固化树脂体时，在混合物的粘度至少为1000mPa·s的状态下进行固化 s。

公开(公告)号：US20120153544A1

公开(公告)日：2012-06-21

申请号：US13128207

申请日：2010-12-16

Applicant: Carlos A. Cruz

Inventor： Carlos A. Cruz

IPC: B29C35/08 ,  C08J9/26 ,  C08L67/00 ,  C08L37/00 ,  C08L77/00

CPC classification number: B01D67/0093 ,  B01D67/0006 ,  B01D67/002 ,  B01D67/003 ,  B01D67/0088 ,  B01D71/26 ,  B01D71/34 ,  B01D71/38 ,  B01D71/40 ,  B01D71/48 ,  B01D2323/30 ,  B01D2323/34 ,  B01D2323/42 ,  B01D2323/50 ,  B29C47/0004 ,  B29C47/0057 ,  B29D7/01 ,  B29K2029/04 ,  B29K2033/04 ,  B29K2033/12 ,  B29K2101/12 ,  B29K2105/0038 ,  B29K2105/0088 ,  B29K2105/24 ,  B29L2031/755 ,  C08J9/0061 ,  C08J9/26 ,  C08J2201/03 ,  C08J2201/0464 ,  C08J2333/10 ,  C08J2351/00 ,  C08J2429/04 ,  C08L21/00 ,  C08L23/06 ,  C08L23/12 ,  C08L27/16 ,  C08L29/04 ,  C08L33/14 ,  C08L67/00 ,  C08L77/00 ,  G05B15/02

Abstract: Technologies and implementations for providing melt processable poly(vinyl alcohol) blends and poly(vinyl alcohol) based membranes are generally disclosed.

Abstract translation: 通常公开了用于提供可熔融加工的聚（乙烯醇）共混物和基于聚（乙烯醇））的膜的技术和实施方案。

公开(公告)号：US20120046622A1

公开(公告)日：2012-02-23

申请号：US13187414

申请日：2011-07-20

Applicant: Jianhong ZHAO ,  Xu Li ,  Ge Chen ,  Jia En Low ,  Kui Liu

Inventor： Jianhong ZHAO ,  Xu Li ,  Ge Chen ,  Jia En Low ,  Kui Liu

IPC: A61L31/16 ,  B29C45/00 ,  A61M25/00 ,  C08J9/26

CPC classification number: B29C67/202 ,  A61K9/0024 ,  A61L27/26 ,  A61L27/54 ,  A61L27/56 ,  A61L27/58 ,  B29C45/0001 ,  B29C45/0053 ,  B29K2995/006 ,  C08J9/26 ,  C08J2201/0464 ,  C08J2300/16 ,  C08J2367/04

Abstract: A method of producing a porous biodegradable medical implant device, the method comprising providing a mixed blend comprising a mixture of at least two biocompatible materials having different degradation or solubility characteristics; molding the mixed blend to produce a molded part; and processing the molded part to remove one of the at least two biocompatible materials by a predetermined amount from the molded part to produce the porous biodegradable medical implant device.

Abstract translation: 一种生产多孔生物可降解医疗植入装置的方法，所述方法包括提供包含具有不同降解或溶解度特性的至少两种生物相容性材料的混合物的混合共混物; 模制混合混合物以制备模制件; 以及处理所述模制部件以从所述模制部件中移除预定量的所述至少两种生物相容性材料中的一种以产生所述多孔可生物降解的医疗植入装置。

公开(公告)号：US09608281B2

公开(公告)日：2017-03-28

申请号：US14355312

申请日：2012-11-20

Applicant: FUTAMURA KAGAKU KABUSHIKI KAISHA

Inventor： Takuzo Imaizumi ,  Hiroaki Nagata ,  Naoki Shiba

IPC: H01M8/0243 ,  H01M8/02 ,  C08J9/26 ,  H01B1/24 ,  C08J9/00 ,  H01M8/10

CPC classification number: H01M8/0243 ,  C08J9/0066 ,  C08J9/008 ,  C08J9/26 ,  C08J2201/03 ,  C08J2201/046 ,  C08J2201/0464 ,  C08J2205/044 ,  C08J2205/048 ,  C08J2205/05 ,  C08J2323/08 ,  C08J2323/12 ,  H01B1/24 ,  H01M8/0234 ,  H01M8/0239 ,  H01M2008/1095 ,  Y02E60/50 ,  Y02P70/56

Abstract: A new conductive interconnected porous film, useful as a material for a gas diffusion layer which is used in a solid polymer type fuel cell, which satisfies the requirements of a good conductivity, good gas permeability, surface smoothness, corrosion resistance, and low impurities and which is strong in bending and excellent in handling to an extent not obtainable by existing sheet materials of carbon fiber, that is, a conductive interconnected porous film wherein a resin base material part of a thermoplastic resin has a porous interconnected cell structure which is formed by removal of removable particulate matter and has cells of sizes of 10 μm to 50 μm and wherein the resin base material part is comprised of different particle size particles of first carbon particles of large size carbon particles of a diameter of 5 μm or more and second carbon particles of micro size carbon particles of a diameter of 10 nm or more mixed together, and a method of production of the same.

公开(公告)号：US20150329675A1

公开(公告)日：2015-11-19

申请号：US14652627

申请日：2013-12-09

Applicant: NITTO DENKO CORPORATION

Inventor： Yumi Takekawa ,  Shinpei Yakuwa ,  Tomoyuki Kasagi ,  Hiroko Ikenaga

IPC: C08G73/10 ,  C09D179/08

CPC classification number: C08G73/10 ,  C08J9/26 ,  C08J2201/026 ,  C08J2201/0464 ,  C08J2205/044 ,  C08J2207/06 ,  C08J2379/08 ,  C09D179/08 ,  H01B3/306 ,  H01B3/427

Abstract: Provided are: a polyetherimide porous body which has a low relative permittivity and is not easily cracked (or is excellent in cracking resistance) when folded, and a method for producing the porous body. This polyetherimide porous body comprises a polyetherimide crosslinked body and has a gel fraction of 10% or more, an average cell diameter of 8 μm or less, a volume porosity of 30% or more and an insulation breakdown voltage of 30 kV/mm or more.

Abstract translation: 提供：折叠时相对介电常数低且不容易龟裂（或抗裂性优异）的聚醚酰亚胺多孔体及其制造方法。 该聚醚酰亚胺多孔体包含聚醚酰亚胺交联体，凝胶分数为10％以上，平均气泡直径为8μm以下，体积孔隙率为30％以上，绝缘击穿电压为30kV / mm以上 。

公开(公告)号：US20150057381A1

公开(公告)日：2015-02-26

申请号：US14504329

申请日：2014-10-01

Applicant: Allergan, Inc.

Inventor： Futian Liu ,  Nicholas J. Manesis ,  Xiaojie Yu ,  Athene Wan Chie Chan

IPC: C08J9/26 ,  B05D1/38 ,  B05D3/00 ,  B05D5/00

CPC classification number: C08J9/26 ,  A61L27/56 ,  A61L31/06 ,  A61L31/146 ,  A61L2400/08 ,  B01D39/1692 ,  B01D2239/1208 ,  B01D2239/1216 ,  B05D1/38 ,  B05D3/007 ,  B05D5/00 ,  C08J2201/04 ,  C08J2201/042 ,  C08J2201/0422 ,  C08J2201/0462 ,  C08J2201/0464 ,  C08J2201/05 ,  C08J2205/05 ,  C08J2207/10 ,  C08J2207/12 ,  C08J2325/10 ,  C08J2353/02 ,  C08J2375/04 ,  C08J2383/04 ,  C09D167/04 ,  C09D171/02

Abstract: Provided are porogen compositions and methods of using such porogen compositions in the manufacture of porous materials, for example, porous silicone elastomers. The porogens generally include comprising a core material and shell material different from the core material. The porogens can be used to form a scaffold for making a resulting porous elastomer when the scaffold is removed.

Abstract translation: 提供的是致孔剂组合物和在制造多孔材料例如多孔硅橡胶中使用这种致孔剂组合物的方法。 致孔剂通常包括芯材和与芯材不同的壳材料。 当去除支架时，致孔剂可用于形成用于制备所得多孔弹性体的支架。

公开(公告)号：US20130049246A1

公开(公告)日：2013-02-28

申请号：US13261454

申请日：2011-04-05

Applicant: Masakazu Minagawa ,  Masashi Teramachi

Inventor： Masakazu Minagawa ,  Masashi Teramachi

IPC: C08J9/26

CPC classification number: B01D67/0011 ,  B01D67/003 ,  B01D69/06 ,  B01D69/08 ,  B01D69/10 ,  B01D71/12 ,  B01D71/34 ,  B01D71/40 ,  B01D71/42 ,  B01D71/48 ,  B01D71/56 ,  B01D71/68 ,  B01D2323/06 ,  B01D2323/22 ,  B01D2325/20 ,  B01D2325/36 ,  C08J9/26 ,  C08J2201/0464 ,  C08J2327/16

Abstract: Disclosed is a process for production of a porous membrane that includes the steps of layering a film-forming dope that contains a polymer (A) that forms a membrane base, a polyvinylpyrrolidone (B) and a solvent (C) into a single layer or two or more layers; immersing the film-forming dope in a solidifying fluid that is a non-solvent with respect to the polymer (A) and is a good solvent with respect to the polyvinylpyrrolidone (B); and removing the polyvinylpyrrolidone (B), wherein the polyvinylpyrrolidone (B) has a K value of 50 to 80, a mass ratio r of the polyvinylpyrrolidone (B) to the polymer (A) is 0.5 or more and less than 1, and the viscosity of the film-forming dope at a membrane production temperature is 100 to 500 Pa·s. Accordingly, by using an appropriate amount of a low-molecular-weight hydrophilic polymer capable of being easily removed, it is possible to produce a porous membrane of a three-dimensional network structure in which macrovoids are suppressed, having high water permeability and superior filtration performance.

Abstract translation: 公开了一种生产多孔膜的方法，其包括以下步骤：将含有形成膜基的聚合物（A），聚乙烯吡咯烷酮（B）和溶剂（C））的成膜原液分层成单层或 两层或多层; 将成膜原液浸渍在相对于聚合物（A）为非溶剂的凝固液中，相对于聚乙烯吡咯烷酮（B）为良好的溶剂; 除去聚乙烯吡咯烷酮（B），其中聚乙烯吡咯烷酮（B）的K值为50〜80，聚乙烯吡咯烷酮（B）与聚合物（A）的质量比r为0.5以上且小于1， 膜生成温度下的成膜原液的粘度为100〜500Pa·s。 因此，通过使用能够容易地除去的适量的低分子量亲水性聚合物，可以制造出抑制大孔，具有高透水性和优异过滤性的三维网状结构的多孔膜 性能。