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公开(公告)号：US20170159082A1
公开(公告)日：2017-06-08
申请号：US15368419
申请日：2016-12-02
CPC分类号： C12P7/26 , C12N9/0006 , C12N9/001 , C12N9/1029 , C12N9/13 , C12N9/88 , C12P11/00 , C12P13/00 , C12P19/32 , C12P21/00 , C12Y101/01035 , C12Y101/011 , C12Y103/01009 , C12Y103/01038 , C12Y203/01016 , C12Y203/01041 , C12Y203/01174 , C12Y203/01179 , C12Y203/0118 , C12Y208/03 , C12Y402/01017
摘要： This document describes biochemical pathways for producing 7-aminoheptanoic acid using a β-ketoacyl synthase or a β-ketothiolase to form either a 5-amino-3-oxopentanoyl-[ACP] or 5-amino-3-oxopentanoyl-CoA intermediate. 7-aminoheptanoic acid can be enzymatically converted to pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol or the corresponding salts thereof. This document also describes recombinant microorganisms producing 7-aminoheptanoic acid as well as pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine and 1,7-heptanediol or the corresponding salts thereof.
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公开(公告)号：US20170218406A1
公开(公告)日：2017-08-03
申请号：US15421164
申请日：2017-01-31
IPC分类号： C12P7/40 , C07C59/147 , C12N9/80 , C12N9/10 , C08G69/10 , C12N9/90 , C12N9/02 , C12P7/24 , C12P17/18 , C08G69/26 , C07C47/21 , C12N9/88
CPC分类号： C12P7/40 , C07C47/21 , C07C59/147 , C08G69/10 , C08G69/26 , C12N9/0008 , C12N9/001 , C12N9/1029 , C12N9/1096 , C12N9/80 , C12N9/88 , C12N9/90 , C12P7/04 , C12P7/24 , C12P7/42 , C12P7/46 , C12P7/50 , C12P7/6409 , C12P7/6427 , C12P13/001 , C12P17/182 , C12Y102/99006 , C12Y103/01031 , C12Y203/01032 , C12Y206/01018 , C12Y305/01 , C12Y402/99 , C12Y503/03008
摘要： This document describes biochemical pathways for producing pimeloyl-CoA using a polypeptide having the enzymatic activity of a hydroperoxide lyase to form non-3-enal and 9-oxononanoate from 9-hydroxyperoxyoctadec-10,12-dienoate. Non-3-enal and 9-oxononanoate can be enzymatically converted to pimeloyl-CoA or a salt thereof using one or more polypeptides having the activity of a dehydrogenase, a CoA ligase, an isomerase, a reductase, a thioesterase, a monooxygenase, a hydratase, and/or a thiolase. Pimeloyl-CoA can be enzymatically converted to pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine, or 1,7-heptanediol, or corresponding salts thereof. This document also describes recombinant microorganisms producing pimeloyl-CoA, as well as pimelic acid, 7-aminoheptanoic acid, 7-hydroxyheptanoic acid, heptamethylenediamine, and 1,7-heptanediol, or corresponding salts thereof.
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公开(公告)号：US20180066296A9
公开(公告)日：2018-03-08
申请号：US15368092
申请日：2016-12-02
CPC分类号： C12P19/32 , C08G69/02 , C12N9/0008 , C12N9/1029 , C12N9/1096 , C12N9/13 , C12P7/18 , C12P7/42 , C12P7/48 , C12P11/00 , C12P13/00 , C12P13/001 , C12P21/00 , C12Y102/99006 , C12Y203/01 , C12Y203/01016 , C12Y203/01041 , C12Y203/01174 , C12Y203/01179 , C12Y203/0118 , C12Y206/01018 , C12Y208/03
摘要： This document describes biochemical pathways for producing 7-aminoheptanoic acid using a β-ketoacyl synthase or a β-ketothiolase to form an N-acetyl-5-amino-3-oxopentanoyl-CoA intermediate. 7-aminoheptanoic acid can be enzymatically converted to pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol or corresponding salts thereof. This document also describes recombinant microorganisms producing 7-aminoheptanoic acid as well as pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine and 1,7-heptanediol or corresponding salts thereof.
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公开(公告)号：US20170159092A1
公开(公告)日：2017-06-08
申请号：US15368092
申请日：2016-12-02
CPC分类号： C12P19/32 , C08G69/02 , C12N9/0008 , C12N9/1029 , C12N9/1096 , C12N9/13 , C12P7/18 , C12P7/42 , C12P7/48 , C12P11/00 , C12P13/00 , C12P13/001 , C12P21/00 , C12Y102/99006 , C12Y203/01 , C12Y203/01016 , C12Y203/01041 , C12Y203/01174 , C12Y203/01179 , C12Y203/0118 , C12Y206/01018 , C12Y208/03
摘要： This document describes biochemical pathways for producing 7-aminoheptanoic acid using a β-ketoacyl synthase or a β-ketothiolase to form an N-acetyl-5-amino-3-oxopentanoyl-CoA intermediate. 7-aminoheptanoic acid can be enzymatically converted to pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine or 1,7-heptanediol or corresponding salts thereof. This document also describes recombinant microorganisms producing 7-aminoheptanoic acid as well as pimelic acid, 7-hydroxyheptanoic acid, heptamethylenediamine and 1,7-heptanediol or corresponding salts thereof.
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