公开(公告)号：US20220396832A1

公开(公告)日：2022-12-15

申请号：US17748498

申请日：2022-05-19

Applicant: Illumina Cambridge Limited ,  Illumina, Inc.

Inventor： Angelica Mariani ,  Antoine Francais ,  Frederick James Topping ,  Christopher Winnard ,  Philip Balding ,  Chol Steven Yun ,  Patrizia Iavicoli

IPC: C12Q1/6869

Abstract: The present application relates to compositions and methods for sequencing by synthesis, where one or more palladium scavengers were used to improve sequencing metrics such phasing and prephasing values.

公开(公告)号：US20240218443A1

公开(公告)日：2024-07-04

申请号：US18393291

申请日：2023-12-21

Applicant: Illumina, Inc.

Inventor： Angelica Mariani ,  Antoine Francais ,  Frederick James Topping ,  Christopher Winnard ,  Philip Balding ,  Chol Steven Yun ,  Patrizia Iavicoli ,  Kathryn Hattingh ,  Xiaolin Wu ,  Xiaohai Liu

IPC: C12Q1/6874 ,  B01J23/44 ,  C12Q1/48 ,  C12Q1/6806 ,  G01N21/64

CPC classification number: C12Q1/6874 ,  B01J23/44 ,  C12Q1/485 ,  C12Q1/6806 ,  G01N21/6486 ,  G01N2333/9126

Abstract: The present application relates to palladium compositions, methods for sequencing by synthesis using nucleotides with 3′ blocking groups, and sequencing kits, where one or more palladium scavengers were used to improve sequencing metrics such phasing and prephasing values.

公开(公告)号：US20250002974A1

公开(公告)日：2025-01-02

申请号：US18758066

申请日：2024-06-28

Applicant: Illumina, Inc.

Inventor： Sherman Lauw ,  Trina Osothprarop ,  Henry Day ,  Johan Basuki ,  Claire Bevis-Mott ,  Hester Beard ,  Chol Steven Yun ,  Faye Huber ,  Patrizia Iavicoli ,  Yin Nah Teo ,  Mei Xian Agnes Lee ,  Denise Ng

IPC: C12Q1/6806 ,  C12Q1/6874

Abstract: This application relates to methods and compositions for protecting fully functional nucleotides (ffNs) against degradation. In some examples, micelles or surfactants are used to protect ffNs. In some examples, bulky cation compounds are used to protect ffNs. In some examples, the compositions that protect ffNs are included in lyophilized material.