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公开(公告)号：US4636218A
公开(公告)日：1987-01-13
申请号：US476757
申请日：1983-03-18
申请人： Isamu Fukuura , Shigeo Niwa
发明人： Isamu Fukuura , Shigeo Niwa
CPC分类号： A61L27/02 , A61F2/30767 , A61F2/32 , A61F2002/3085 , A61F2002/30929 , A61F2002/30968 , A61F2002/3233 , A61F2002/3493 , A61F2310/00203 , A61F2310/00239 , A61F2310/00317 , A61F2310/00335
摘要： An artificial articulation includes a socket which has a spherical inner surface, a bone head ball member which is pivotably, slidably received in the spherical inner surface of the socket, and a stem which is connected to the ball head bone member. The socket is made of polycrystal alumina porcelain, the bone head ball member is made of dense silicon nitride porcelain, and the stem is made of either silicon nitride porcelain or partially stabilized zirconia porcelain. An outer surface of the stem and outer surface of the socket are coated with first and second cover layer.
摘要翻译： 人造关节包括具有球形内表面的插座，可枢转地可滑动地容纳在插座的球形内表面中的骨头球部件，以及连接到球头骨部件的杆。 插座由多晶氧化铝陶瓷制成，骨头球部件由致密的氮化硅瓷制成，该杆由氮化硅瓷或部分稳定的氧化锆瓷制成。 杆的外表面和插座的外表面涂覆有第一和第二覆盖层。
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2.发明授权Biomedical material including tube-like biodegradeable nety works filled with hydroxylapatite 失效生物医学材料，包括管状可生物降解的工程，填充羟基磷灰石
公开(公告)号：US5665120A
公开(公告)日：1997-09-09
申请号：US596914
申请日：1996-03-15
申请人： Torao Ohtsuka , Makoto Fukaya , Hideo Tagai , Shigeo Niwa , Kazuhiko Sawai , Hajime Ohta
发明人： Torao Ohtsuka , Makoto Fukaya , Hideo Tagai , Shigeo Niwa , Kazuhiko Sawai , Hajime Ohta
CPC分类号： A61L27/34 , A61F2/28 , A61L27/12 , A61F2002/30062 , A61F2002/30235 , A61F2210/0004 , A61F2230/0069 , A61F2310/00293
摘要： A biomedical material in use for curing the bone defect or the like in human being or an animal. The biomedical material is comprised of a flexible fiber-meshed micro-tube which has an outer diameter ranging from 50 .mu.m to 10 mm and is formed of a net or a cloth woven from fibers. The fibers are biodegradable and capable of maintaining their shape within a time period ranging from 1 week to 30 weeks in the body. Additionally, hydroxylapatite beads and/or flakes are filled in the fiber-meshed micro-tube. The biomedical material is located in the bone defect or the like under an operation, in which blood can effectively circulate through the mesh of the micro-tube and through the spaces among the hydroxylapatite beads and/or flakes, thereby promoting the cure of the bone defect or the like.
摘要翻译： 用于治疗人或动物中的骨缺损等的生物医学材料。 生物医学材料由具有50μm至10mm的外径的柔性纤维网状微管组成，并由纤维编织的网或织物形成。 纤维是可生物降解的，并且能够在体内在1周至30周的时间段内保持其形状。 另外，羟基磷灰石珠和/或薄片填充在纤维网状微管中。 生物医学材料在手术中位于骨缺损等中，其中血液可以有效地循环通过微管的网格并通过羟磷灰石珠和/或薄片之间的空间，从而促进骨的固化 缺陷等。
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公开(公告)号：US4994085A
公开(公告)日：1991-02-19
申请号：US320436
申请日：1989-03-08
申请人： Kazuhiko Sawai , Shigeo Niwa , Tomokazu Hattori , Wataru Yagi , Ryohei Yabuno , Masami Ishii
发明人： Kazuhiko Sawai , Shigeo Niwa , Tomokazu Hattori , Wataru Yagi , Ryohei Yabuno , Masami Ishii
CPC分类号： A61B17/8802 , A61F2/30723 , A61F2/30724 , A61F2/3662 , A61F2/36 , A61F2/4684 , A61F2002/30354 , A61F2002/30726 , A61F2002/3694 , A61F2002/4631 , A61F2220/0033 , A61F2310/00017 , A61F2310/00023 , A61F2310/00029 , A61F2310/00203 , A61F2310/00239 , A61F2310/00293 , A61F2310/00353
摘要： An artificial stem unit for coxa with a setting guide comprises a stem made of metal to be inserted into the marrow cavity of a femur and a setting guide for fixing the stem in the marrow cavity comprising a cylindrical core rod and a plug attached to the end of the cylindrical core rod. In the operation, the setting guide is inserted into the marrow cavity of the femur in advance for the centering, and thereafter, the stem is inserted so that the through hole of the stem fit with the cylindrical core rod of the setting guide. Then the bone cement is injected to fix the stem at an accurate position set up by the above operation.
摘要翻译： 具有定位引导件的用于髋骨的人造茎单元包括由金属制成的杆以插入股骨的骨髓腔中，以及用于将杆固定在骨髓腔中的定位引导件，其包括圆柱形芯棒和附接到端部的插头 的圆柱形芯棒。 在操作中，将定位引导件预先插入到股骨的骨髓腔中以进行定心，然后插入杆，使得杆的通孔与安装引导件的圆柱形芯棒配合。 然后注入骨水泥以将柄固定在由上述操作设定的准确位置。
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公开(公告)号：US4429691A
公开(公告)日：1984-02-07
申请号：US342259
申请日：1982-01-25
申请人： Shigeo Niwa , Kazuhiko Sawai , Shinobu Takahashi , Hideo Tagai , Mikiya Ono , Yoshiaki Fukuda , Hiroyasu Takeuchi
发明人： Shigeo Niwa , Kazuhiko Sawai , Shinobu Takahashi , Hideo Tagai , Mikiya Ono , Yoshiaki Fukuda , Hiroyasu Takeuchi
IPC分类号： A61L27/00 , A61D1/00 , A61F2/00 , A61F2/28 , A61K6/033 , A61K33/42 , A61L27/12 , C01B25/32 , A61F1/00
CPC分类号： A61K33/42 , A61L27/12 , A61F2002/2835 , A61F2002/30084 , A61F2310/00293
摘要： A filler for filling in defects or hollow portions of bones to coalesce with the bone tissues is provided which comprises powders of a calcium phosphate compound having the apatite crystalline structure of each crystal grain size of from 50 .orgate. to 10 microns and represented by the following general formula of Ca.sub.m (PO.sub.4).sub.n OH (1.33.ltoreq.m/n.ltoreq.1.95); and said powders being adapted for filling in a fluidized or plasticized state. A method of treating a bone with the filler is also provided wherein at least a portion of said filler is filled in to reach the bone-marrow cavity of said bone.
摘要翻译： 提供了用于填充骨骼的缺陷或中空部分以与骨组织聚结的填充物，其包含磷酸钙化合物的粉末，其具有每个晶粒尺寸为50微米至约10微米的磷灰石晶体结构，并由以下通用 凸轮（PO4）nOH（1.33≤m/ n <1.95）的配方; 并且所述粉末适于填充流化或塑化状态。 还提供了用填料处理骨的方法，其中至少一部分所述填料被填充以到达所述骨的骨髓腔。
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公开(公告)号：US5013323A
公开(公告)日：1991-05-07
申请号：US86247
申请日：1987-08-13
申请人： Masahiro Kobayashi , Hideo Tagai , Yoshikatsu Kuroki , Shigeo Niwa , Mikiya Ono
发明人： Masahiro Kobayashi , Hideo Tagai , Yoshikatsu Kuroki , Shigeo Niwa , Mikiya Ono
摘要： An implant material for replacing hard tissue of a living body is provided. The implant material comprises 10 to 90 wt % of a fiber glass and 90 to 10 wt % of an organic high polymer material. The fiber glass is mainly composed of calcium phosphate. The organic high polymer material does not inhibit affinity with the living body. On the surface of the implant material, a portion of the fiber glass is exposed.
摘要翻译： 提供了用于替代生物体的硬组织的植入材料。 植入材料包含10至90重量％的玻璃纤维和90至10重量％的有机高分子材料。 玻璃纤维主要由磷酸钙组成。 有机高分子材料不抑制与生物的亲和力。 在植入材料的表面上，露出一部分玻璃纤维。
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公开(公告)号：US4820573A
公开(公告)日：1989-04-11
申请号：US91367
申请日：1987-08-28
申请人： Hideo Tagai , Masahiro Kobayashi , Shigeo Niwa , Hiroyasu Takeuchi , Mikiya Ono
发明人： Hideo Tagai , Masahiro Kobayashi , Shigeo Niwa , Hiroyasu Takeuchi , Mikiya Ono
CPC分类号： A61L27/12 , A61L27/32 , C03C13/00 , A61F2310/00293 , A61F2310/00796 , A61L2430/02 , Y10T442/3976
摘要： A fiber glass is provided for filling in a defect or hollow portion of bone. The fiber glass comprises calcium phosphate as a main ingredient and has a negative zeta potential. The calcium phosphate has a molar ratio of Ca/P of not less than 0.2 and less than 0.6 and the total content of CaO plus P.sub.2 O.sub.5 in the fiber glass is less than 80 wt %. The fiber glass is of long filament form or staple fiber form. The fiber glass of long filament form may be woven to form a woven filler.
摘要翻译： 提供玻璃纤维用于填充骨的缺损或中空部分。 玻璃纤维以磷酸钙为主要成分，具有负ζ电位。 磷酸钙的Ca / P摩尔比不小于0.2且小于0.6，并且玻璃纤维玻璃中的CaO + P2O5的总含量小于80重量％。 玻璃纤维是长纤维形式或短纤维形式。 长丝形状的玻璃纤维可以被编织以形成编织填料。
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公开(公告)号：US4735857A
公开(公告)日：1988-04-05
申请号：US883235
申请日：1986-07-08
申请人： Hideo Tagai , Masahiro Kobayashi , Shigeo Niwa , Hiroyasu Takeuchi , Mikiya Ono
发明人： Hideo Tagai , Masahiro Kobayashi , Shigeo Niwa , Hiroyasu Takeuchi , Mikiya Ono
CPC分类号： A61L27/12 , A61L27/32 , C03C13/00 , A61F2310/00293 , A61F2310/00796 , A61L2430/02
摘要： A fiber glass is provided for filling in a defect or hollow portion of bone. The fiber glass comprises calcium phosphate as a main ingredient and has a negative zeta potential. The calcium phosphate has a molar ratio of Ca/P of not less than 0.2 and less than 0.6 and the total content of CaO plus P.sub.2 O.sub.5 less than 80 wt %. The fiber glass is of long filament form or staple fiber form. The fiber glass of long filament form may be woven to form a woven filler.
摘要翻译： 提供玻璃纤维用于填充骨的缺损或中空部分。 玻璃纤维以磷酸钙为主要成分，具有负ζ电位。 磷酸钙的Ca / P摩尔比不小于0.2且小于0.6，CaO和P2O5的总含量小于80重量％。 玻璃纤维是长纤维形式或短纤维形式。 长丝形状的玻璃纤维可以被编织以形成编织填料。
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8.发明授权
公开(公告)号：US5266248A
公开(公告)日：1993-11-30
申请号：US960578
申请日：1992-10-13
申请人： Torao Ohtsuka , Makoto Fukaya , Hideo Tagai , Takayuri Kato , Shinpei Hashimoto , Kazuhiko Sawai , Tomokazu Hattori , Shigeo Niwa
发明人： Torao Ohtsuka , Makoto Fukaya , Hideo Tagai , Takayuri Kato , Shinpei Hashimoto , Kazuhiko Sawai , Tomokazu Hattori , Shigeo Niwa
CPC分类号： C04B38/009 , A61F2/28 , A61L27/12 , A61F2/3094 , A61F2002/30677 , A61F2250/0067 , A61F2310/00293 , C04B2111/00836
摘要： A method of producing a hydroxylapatite base porous beads filler for an organism, including mixing hydroxylapatite powder having particle sizes not larger than 125 .mu.m, in an amount ranging from 40 to 90% by weight, synthetic resin powder having particle sizes not larger than 74 .mu.m, in an amount ranging from 5 to 55% by weight, and resinous binder in an amount ranging from 0.5 to 5% by weight to obtain a mixture, granulating the mixture to form beads each having a diameter ranging from 0.03 to 25 mm, firing the beads at a temperature ranging from 900.degree. C. to 1180.degree. C. to form hydroxylapatite base porous beads, dipping the porous beads in a colloidal solution, removing air from the porous beads under vacuum, and filling the colloidal solution into the pores in the porous beads under pressure.
摘要翻译： 一种制备用于生物体的羟基磷灰石基多孔珠填料的方法，包括混合粒度不大于125μm的羟基磷灰石粉末，其量为40至90重量％，粒径不大于74的合成树脂粉末 以5至55重量％的量加入，树脂粘合剂的量为0.5-5重量％，以获得混合物，制成混合物，形成直径范围为0.03至25毫米的珠粒 在900〜1180℃的温度下烧成珠，形成羟基磷灰石基多孔珠，将多孔珠浸入胶体溶液中，真空除去多孔珠粒中的空气，并将胶体溶液填充到 压力下的多孔珠孔。
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公开(公告)号：US4979958A
公开(公告)日：1990-12-25
申请号：US412307
申请日：1989-09-26
申请人： Shigeo Niwa , Kazuhiko Sawai , Tomokazu Hattori , Yasumasa Matsuda , Wataru Yagi , Masami Ishii , Junichi Mita , Masuo Yamada
发明人： Shigeo Niwa , Kazuhiko Sawai , Tomokazu Hattori , Yasumasa Matsuda , Wataru Yagi , Masami Ishii , Junichi Mita , Masuo Yamada
CPC分类号： A61F2/30767 , A61F2/36 , A61F2/367 , A61F2/3672 , A61F2/3676 , A61F2002/30112 , A61F2002/30149 , A61F2230/0004 , A61F2230/0017
摘要： An artificial stem for femur of coxa in a human body comprises a stem element, a head and a neck connecting the both, each side surface of the stem element corresponding to the indise or outside of a human body being formed by a specific curved or straight line respectively, the cross section of the stem element having a specific shape, and scale-like step patterns being formed on both the front and back surfaces, thereby improving the fitness to the femur of a small body person like Japanese, the stability and the anti-twisting strength after insertion.
摘要翻译： 用于人体的髋关节股骨的人造茎包括杆元件，头部和连接两者的颈部，杆元件的每个侧表面对应于人体的不同或外部，由特定的弯曲或直线形成 线状元件的横截面具有特定的形状，并且在前表面和后表面上形成鳞片状台阶图案，从而提高了像日本人这样的小身体人的股骨的适应性，稳定性和 插入后抗扭强度。
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公开(公告)号：US4613577A
公开(公告)日：1986-09-23
申请号：US624658
申请日：1984-06-26
申请人： Hideo Tagai , Masahiro Kobayashi , Shigeo Niwa , Hiroyasu Takeuchi , Mikiya Ono
发明人： Hideo Tagai , Masahiro Kobayashi , Shigeo Niwa , Hiroyasu Takeuchi , Mikiya Ono
CPC分类号： A61L27/12 , A61L27/32 , C03C13/00 , A61F2310/00293 , A61F2310/00796 , A61L2430/02
摘要： A fiber glass is provided for filling in a defect or hollow portion of bone. The fiber glass comprises calcium phosphate as a main ingredient and has a negative zeta potential. The calcium phosphate has a molar ratio of Ca/P of not less than 0.2 and less than 0.6 and the total content of CaO plus P.sub.2 O.sub.5 in the fiber glass is less than 80 wt %. The fiber glass is of long filament form or staple fiber form. The fiber glass of long filament form may be woven to form a woven filler.
摘要翻译： 提供玻璃纤维用于填充骨的缺损或中空部分。 玻璃纤维以磷酸钙为主要成分，具有负ζ电位。 磷酸钙的Ca / P摩尔比不小于0.2且小于0.6，并且玻璃纤维玻璃中的CaO + P2O5的总含量小于80重量％。 玻璃纤维是长纤维形式或短纤维形式。 长丝形状的玻璃纤维可以被编织以形成编织填料。
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