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    PLATELET ANALYSIS
    3.
    发明申请
    PLATELET ANALYSIS 有权
    平板电脑分析

    公开(公告)号：US20110263452A1

    公开(公告)日：2011-10-27

    申请号：US13123411

    申请日：2009-10-12

    申请人： Lourdes Basabe-Desmonts ,  Sofia Ramstrom ,  Antonio Ricco ,  Kenny Dermot ,  Gerardene Meade ,  Sarah O'Neill ,  Asif Riaz ,  Luke Lee

    发明人： Lourdes Basabe-Desmonts ,  Sofia Ramstrom ,  Antonio Ricco ,  Kenny Dermot ,  Gerardene Meade ,  Sarah O'Neill ,  Asif Riaz ,  Luke Lee

    IPC分类号： C40B30/04 ,  C40B60/12

    CPC分类号： G01N33/5094 ,  G01N33/5091

    摘要： The present invention relates to a method, including a diagnostic method, for characterising platelets. More particularly, the invention relates to methods for characterising platelets by immobilising platelets on a substrate for detection and subsequent characterisation, and to devices on which such a method may be practiced. The method comprises the steps of:—a.contacting a substrate that includes a plurality of discrete platelet- binding zones having a surface area of 7850 μm2 orless with a fluid composition comprising platelets; and b.detecting platelets bound to the platelet-binding zones and thereby characterising platelets.

    摘要翻译： 本发明涉及一种包括用于表征血小板的诊断方法。 更具体地说，本发明涉及通过将血小板固定在基底上进行检测和随后的表征来表征血小板的方法以及可以在其上实施这种方法的装置。 该方法包括以下步骤： - 使包含表面积为7850μm2的多个离散血小板结合区的基片与包含血小板的流体组合物接触; 并且b检测与血小板结合区结合的血小板，从而表征血小板。

    Microfluidic device for assessing object/test material interactions
    6.
    发明授权
    Microfluidic device for assessing object/test material interactions 有权
    用于评估物体/测试材料相互作用的微流体装置

    公开(公告)号：US09378557B2

    公开(公告)日：2016-06-28

    申请号：US12866351

    申请日：2009-02-05

    申请人： Nigel Kent ,  Bryan Lincoln ,  Lourdes Basabe-Desmonts ,  Antonio Ricco ,  Dermot Kenny ,  Gerardene Meade ,  Brian Corcoran

    发明人： Nigel Kent ,  Bryan Lincoln ,  Lourdes Basabe-Desmonts ,  Antonio Ricco ,  Dermot Kenny ,  Gerardene Meade ,  Brian Corcoran

    IPC分类号： B01L3/00 ,  G06T7/20

    CPC分类号： G06T7/2033 ,  B01L3/502715 ,  B01L3/502776 ,  B01L2200/0636 ,  B01L2300/0636 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/0877 ,  B01L2300/163 ,  B01L2400/084 ,  G06T7/246 ,  G06T2207/10016 ,  G06T2207/10056 ,  G06T2207/30024 ,  G06T2207/30241

    摘要： An object/test material interaction microti iridic device comprising a sample inlet adapted to receive a fluid sample comprising a plurality of objects, an outlet adapted to output the fluid sample from the device, at least one internal surface defining a flow cavity within the device, wherein the flow cavity extends between and is connected to the sample inlet and the outlet for flow of the fluid sample through the flow cavity, the flow cavity comprises a test area to which at least one test material is attached and which is situated in the flow cavity for flow of the fluid sample over the test area, and the flow cavity has an aspect ratio which, when the flow cavity is substantially filled by the fluid sample, provides a substantially constant shear force between the test area and the fluid sample flowing over the test area. The invention further comprises a system incorporating the device, methods of use of the device and system, and methods of analyzing interactions.

    摘要翻译： 一种物体/测试材料相互作用微卫星设备，包括适于接收包含多个物体的流体样品的样品入口，适于从该装置输出流体样品的出口，至少一个限定器件内的流动腔的内表面， 其中所述流动空腔在所述样品入口和所述出口之间延伸并且连接到所述流体样品通过所述流动腔的流动，所述流动腔包括测试区域，至少一个测试材料附接到所述测试区域并且位于所述流动 用于流体样品在测试区域上流动的空腔，并且流动空腔具有纵横比，当流动腔基本上被流体样品填充时，其在测试区域和流动样品流动之间提供基本上恒定的剪切力 测试区域。 本发明还包括结合该装置的系统，该装置和系统的使用方法以及分析相互作用的方法。