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公开(公告)号：US20100315588A1
公开(公告)日：2010-12-16
申请号：US12456422
申请日：2009-06-16
申请人： Ivan M. Nunez , Jeffrey G. Linhardt , Joseph A. McGee , Jennifer Hunt , Michele Alton , Devon A. Shipp , Jay F. Kunzler , Daniel M. Ammon, JR.
发明人： Ivan M. Nunez , Jeffrey G. Linhardt , Joseph A. McGee , Jennifer Hunt , Michele Alton , Devon A. Shipp , Jay F. Kunzler , Daniel M. Ammon, JR.
摘要： Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a hydrophilic polymer comprising one or more hydrophilic units and one or more thio carbonyl thio fragments of a reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed.
摘要翻译： 生物医学装置，例如由混合物的聚合产物形成的隐形眼镜，所述混合物包含（a）包含一个或多个亲水单元的亲水性聚合物和一个或多个可逆加成断裂链转移（“RAFT”）试剂的一个或多个硫羰基硫代片段; 和（b）公开了一种或多种生物医学装置形成单体。
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公开(公告)号：US20100317809A1
公开(公告)日：2010-12-16
申请号：US12456419
申请日：2009-06-16
申请人： Jeffrey G. Linhardt , Ivan M. Nunez , Joseph A. McGee , Jennifer Hunt , Michele Alton , Drazen Pavlovic , Devon A. Shipp
发明人： Jeffrey G. Linhardt , Ivan M. Nunez , Joseph A. McGee , Jennifer Hunt , Michele Alton , Drazen Pavlovic , Devon A. Shipp
IPC分类号： C08L83/06
CPC分类号： G02B1/043 , A61L27/18 , A61L27/52 , A61L2430/16 , C08L83/10
摘要： Biomedical devices such as silicone hydrogels formed from a polymerization product of a mixture comprising (a) a siloxane-containing homopolymer comprising one or more thio carbonyl thio fragments of a reversible addition fragmentation chain transfer (RAFT) agent; and (b) one or more biomedical device-forming monomers are disclosed.
摘要翻译： 生物医学装置例如由混合物的聚合产物形成的硅氧烷水凝胶，所述混合物包含（a）包含可逆加成断裂链转移（RAFT）试剂的一个或多个硫羰基硫代片段的含硅氧烷的均聚物; 和（b）公开了一种或多种生物医学装置形成单体。
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公开(公告)号：US08337551B2
公开(公告)日：2012-12-25
申请号：US13226691
申请日：2011-09-07
申请人： Jeffrey G. Linhardt , Ivan M. Nunez , Joseph A. McGee , Jennifer Hunt , Michele Alton , Drazen Pavlovic , Devon A. Shipp
发明人： Jeffrey G. Linhardt , Ivan M. Nunez , Joseph A. McGee , Jennifer Hunt , Michele Alton , Drazen Pavlovic , Devon A. Shipp
CPC分类号： G02B1/043 , A61L27/18 , A61L27/52 , A61L2430/16 , C08L83/10
摘要： Biomedical devices such as silicone hydrogels formed from a polymerization product of a mixture comprising (a) a siloxane-containing homopolymer which has only one thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (RAFT) agent; and (b) one or more biomedical device-forming comonomers are disclosed.
摘要翻译： 生物医学装置，例如由混合物的聚合产物形成的硅氧烷水凝胶，所述混合物包含（a）仅含有一个可逆加成断裂链转移（RAFT）试剂的硫代羰基硫代片段的含硅氧烷的均聚物; 和（b）公开了一种或多种生物医学装置形成共聚单体。
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公开(公告)号：US20120022180A1
公开(公告)日：2012-01-26
申请号：US13226691
申请日：2011-09-07
申请人： Jeffrey G. Linhardt , Ivan M. Nunez , Joseph A. McGee , Jennifer Hunt , Michele Alton , Drazen Pavlovic , Devon A. Shipp
发明人： Jeffrey G. Linhardt , Ivan M. Nunez , Joseph A. McGee , Jennifer Hunt , Michele Alton , Drazen Pavlovic , Devon A. Shipp
IPC分类号： G02C7/04 , C08F283/12 , A61F2/16 , C08L83/08
CPC分类号： G02B1/043 , A61L27/18 , A61L27/52 , A61L2430/16 , C08L83/10
摘要： Biomedical devices such as silicone hydrogels formed from a polymerization product of a mixture comprising (a) a siloxane-containing homopolymer which has only one thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (RAFT) agent; and (b) one or more biomedical device-forming comonomers are disclosed.
摘要翻译： 生物医学装置，例如由混合物的聚合产物形成的硅氧烷水凝胶，所述混合物包含（a）仅含有一个可逆加成断裂链转移（RAFT）试剂的硫代羰基硫代片段的含硅氧烷的均聚物; 和（b）公开了一种或多种生物医学装置形成共聚单体。
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公开(公告)号：US08043369B2
公开(公告)日：2011-10-25
申请号：US12456419
申请日：2009-06-16
申请人： Jeffrey G. Linhardt , Ivan M. Nunez , Joseph A. McGee , Jennifer Hunt , Michele Alton , Drazen Pavlovic , Devon A. Shipp
发明人： Jeffrey G. Linhardt , Ivan M. Nunez , Joseph A. McGee , Jennifer Hunt , Michele Alton , Drazen Pavlovic , Devon A. Shipp
CPC分类号： G02B1/043 , A61L27/18 , A61L27/52 , A61L2430/16 , C08L83/10
摘要： Biomedical devices such as silicone hydrogels formed from a polymerization product of a mixture comprising (a) a siloxane-containing homopolymer comprising one or more thio carbonyl thio fragments of a reversible addition fragmentation chain transfer (RAFT) agent; and (b) one or more biomedical device-forming monomers are disclosed.
摘要翻译： 生物医学装置例如由混合物的聚合产物形成的硅氧烷水凝胶，所述混合物包含（a）包含可逆加成断裂链转移（RAFT）试剂的一个或多个硫羰基硫代片段的含硅氧烷的均聚物; 和（b）公开了一种或多种生物医学装置形成单体。
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公开(公告)号：US09285508B2
公开(公告)日：2016-03-15
申请号：US12456423
申请日：2009-06-16
摘要： Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a multi-armed macromonomer comprising multiple side chains attached to a nucleus, wherein each side chain comprises a thio carbonyl thio fragment of the same or different reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed.
摘要翻译： 生物医学装置，例如由混合物的聚合产物形成的隐形眼镜，所述混合物包含（a）包含连接到核的多个侧链的多臂大分子单体，其中每个侧链包含相同或不同的可逆加成断裂的硫代羰基硫代片段 链转移（“RAFT”）代理; 和（b）公开了一种或多种生物医学装置形成单体。
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公开(公告)号：US20100318185A1
公开(公告)日：2010-12-16
申请号：US12456423
申请日：2009-06-16
摘要： Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a multi-armed macromonomer comprising multiple side chains attached to a nucleus, wherein each side chain comprises a thio carbonyl thio fragment of the same or different reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed.
摘要翻译： 生物医学装置，例如由混合物的聚合产物形成的隐形眼镜，所述混合物包含（a）包含连接到核的多个侧链的多臂大分子单体，其中每个侧链包含相同或不同的可逆加成断裂的硫代羰基硫代片段 链转移（“RAFT”）代理; 和（b）公开了一种或多种生物医学装置形成单体。
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公开(公告)号：US20120329905A1
公开(公告)日：2012-12-27
申请号：US13483397
申请日：2012-05-30
申请人： Ivan M. Nunez , Jay F. Kunzler , Jennifer Hunt , Joseph A. McGee
发明人： Ivan M. Nunez , Jay F. Kunzler , Jennifer Hunt , Joseph A. McGee
IPC分类号： C08G63/688 , C07C333/20 , C07C333/04 , C08L81/00
CPC分类号： C07C333/04
摘要： An optical copolymer comprising: a constituent derived from a sulfated lens monomer of general formula I [PG-R1—NHC(Y)S—R2]n—R3 I PG is a polymerizable group selected from the group consisting of vinyl, acryloyl, acryoyloxy, methacryoyl and methacryoyloxy; acrylamido and methacrylamido; Y is oxygen or sulfur; and n is 2, 3 or 4. Also, R1 is an organic group of one to eight carbon atoms and optionally with one or more oxygen atoms or an aromatic ring. R2 is a bond or an organic group of one to six carbon atoms. R3 is a bond, an organic group of one to ten carbons atoms, carbon, oxygen, sulfur or a disulfide; and a lens monomer. The sulfated lens monomer is derived from a first component of formula, PG-R1—NC(Y), and a polythiol of formula, R3—[R2—SH]n.
摘要翻译： 一种光学共聚物，其包含：衍生自通式I的硫酸化透镜单体的组分[PG-R 1 -NHC（Y）S-R 2] n -R 3 I PG是选自乙烯基，丙烯酰基，丙烯酰氧基 ，甲基丙烯酰基和甲基丙烯酰氧基; 丙烯酰胺和甲基丙烯酰胺; Y是氧或硫; n为2,3或4.另外，R 1为碳原子数为1〜8的有机基团，且可以具有一个以上的氧原子或芳香环。 R2是1-6个碳原子的键或有机基团。 R3是一个键，一至十个碳原子的有机基团，碳，氧，硫或二硫键; 和透镜单体。 硫酸化透镜单体衍生自式的第一组分PG-R1-NC（Y）和式R3- [R2-SH] n的多硫醇。
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公开(公告)号：US20100317817A1
公开(公告)日：2010-12-16
申请号：US12456421
申请日：2009-06-16
摘要： Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a random copolymer comprising hydrophilic units and hydrophobic units, wherein the random copolymer has at least one thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (“RAFT”) agent are disclosed.
摘要翻译： 生物医学装置如由混合物的聚合产物形成的隐形眼镜，所述混合物包含（a）包含亲水单元的无规共聚物和疏水单元，其中所述无规共聚物具有至少一个可逆加成断裂链转移的硫代羰基硫代片段（“RAFT “）代理。
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公开(公告)号：US08133960B2
公开(公告)日：2012-03-13
申请号：US12456421
申请日：2009-06-16
IPC分类号： C08F226/06 , C08F30/08 , C08F12/30 , C08G75/00
摘要： Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a random copolymer comprising hydrophilic units and hydrophobic units, wherein the random copolymer has at least one thio carbonyl thio fragment of a reversible addition fragmentation chain transfer (“RAFT”) agent are disclosed.
摘要翻译： 生物医学装置如由混合物的聚合产物形成的隐形眼镜，所述混合物包含（a）包含亲水单元的无规共聚物和疏水单元，其中所述无规共聚物具有至少一个可逆加成断裂链转移的硫代羰基硫代片段（“RAFT “）代理。
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