公开(公告)号：US06212186B1

公开(公告)日：2001-04-03

申请号：US08979431

申请日：1997-11-26

申请人： Iwao Tada ,  Jyoei Kamoi ,  Tomoyuki Yamaguchi ,  Naoki Aihara

发明人： Iwao Tada ,  Jyoei Kamoi ,  Tomoyuki Yamaguchi ,  Naoki Aihara

IPC分类号： H04L1256

CPC分类号： H04L49/3081 ,  H04L2012/5636 ,  H04Q11/0478

摘要： The invention concerns an ATM exchange, and is directed in particular to the provision of a cell bandwidth control apparatus for performing bandwidth control for ATM cells sent from the ATM exchange onto the line side. The cell bandwidth control apparatus includes forced empty cell inserting means for forcibly inserting empty cells in a highway connected to an ATM switch. The forced empty cell inserting means inserts forced empty cells in an outgoing highway leading from the ATM switch to a line adapter and thereby limits the line bandwidth of the outgoing highway to within the bandwidth of the line accommodated in the line adapter.

摘要翻译： 本发明涉及ATM交换机，特别涉及提供一种用于对从ATM交换机发送到线路侧的ATM信元进行带宽控制的小区带宽控制装置。 小区带宽控制装置包括用于在连接到ATM交换机的高速公路中强制插入空单元的强制空单元插入装置。 强制空单元插入装置将从ATM交换机引出的输出高速公路中的强制空单元插入线路适配器，从而将输出高速公路的线路带宽限制在线路适配器中线路的带宽内。

公开(公告)号：US06446146B1

公开(公告)日：2002-09-03

申请号：US09296841

申请日：1999-04-22

申请人： Tomoyuki Yamaguchi ,  Jyoei Kamoi ,  Iwao Tada

发明人： Tomoyuki Yamaguchi ,  Jyoei Kamoi ,  Iwao Tada

IPC分类号： G06F1300

CPC分类号： H04L49/606 ,  G06F13/4086 ,  H04J3/0685 ,  H04J2203/0089 ,  H04L12/5601 ,  H04L49/3081 ,  H04L2012/5674

摘要： To reduce a scale of the circuit, a number of the external terminals, processing steps in developing a firmware, and a scale of the firmware, a line terminator provided in a device for terminating SONET/SDH lines, each having a different line speed, terminates plural lines, each having a different line speed, and includes a clock generator generating a clock corresponding to each line speed, a line switching circuit for specifying one of the plural lines, a selector for outputting data of one of the plural lines, which is specified by the line switching circuit, and a common processing circuit for processing data of the one line output from the selector, according to a clock corresponding to the line speed generated in the clock generator.

摘要翻译： 为了减少电路的规模，多个外部终端，开发固件的处理步骤和固件的规模，设置在用于终止SONET / SDH线路的设备中的线路终端器，每个线路终端器具有不同的线路速度， 终止多行，每行具有不同的线速度，并且包括产生与每行线速度相对应的时钟的时钟发生器，用于指定多条线之一的线切换电路，用于输出多条线之一的数据的选择器， 由线路切换电路指定，以及公共处理电路，用于根据对应于在时钟发生器中产生的线路速度的时钟处理从选择器输出的一行的数据。

公开(公告)号：US06856594B1

公开(公告)日：2005-02-15

申请号：US09634387

申请日：2000-08-09

申请人： Naoki Aihara ,  Hichiro Hayami ,  Iwao Tada ,  Tomoyuki Yamaguchi

发明人： Naoki Aihara ,  Hichiro Hayami ,  Iwao Tada ,  Tomoyuki Yamaguchi

IPC分类号： H04L1/22 ,  H04L12/70 ,  H04L12/56

CPC分类号： H04L12/5601 ,  H04L1/22 ,  H04L2012/5625 ,  H04L2012/5627

摘要： A method and system including ATM switching equipment provided for switching between a working channel and a protection channel in an ATM network. The method and system include the following processes: In each cell for transmission providing an indication of whether the cell belongs connection currently in a working state via a working channel; cells are duplicated on each connection basis; the duplicated cells are transmitted simultaneously on both a working channel and a protection channel; and valid cells are selected from received cells according to the indication in each cell indicating whether the relevant connection is currently in a working state.

摘要翻译： 一种包括提供用于在ATM网络中的工作信道和保护信道之间切换的ATM交换设备的方法和系统。 该方法和系统包括以下过程：在每个传输小区中，通过工作信道提供该小区是否属于当前处于工作状态的连接的指示; 在每个连接的基础上复制单元; 复制的小区在工作信道和保护信道上同时传输; 并且根据每个小区中的指示来指示相关连接是否处于工作状态，从接收到的小区中选择有效小区。

公开(公告)号：US06026098A

公开(公告)日：2000-02-15

申请号：US931638

申请日：1997-09-16

申请人： Jyoei Kamoi ,  Tomoyuki Yamaguchi ,  Mikio Nakayama ,  Yuzo Okuyama

发明人： Jyoei Kamoi ,  Tomoyuki Yamaguchi ,  Mikio Nakayama ,  Yuzo Okuyama

IPC分类号： H04J3/04 ,  H04J3/24 ,  H04Q11/04 ,  H04L12/56

CPC分类号： H04L49/3081 ,  H04J3/247 ,  H04Q11/0478 ,  H04L2012/5672

摘要： A plurality of input lines are respectively connected to separate multiplexing units that are connected in cascade by cascading lines. Select signals are transferred in parallel with fixed length packets over the cascading lines. Each separate multiplexing unit is responsive to a select signal received from the cascading line to select one of fixed length packets received over the corresponding input line and the upstream cascading line and output it over the downstream cascading line. The most downstream separate multiplexing unit provides a multiplexed output of the input lines.

摘要翻译： 多个输入线分别连接到通过级联线级联连接的分离复用单元。 选择信号通过级联线路与固定长度的数据包并行传输。 每个单独的复用单元响应于从级联线路接收的选择信号，以选择在相应输入线路和上游级联线路上接收的固定长度分组中的一个，并在下游级联线路上输出。 最下游单独复用单元提供输入线的多路复用输出。

公开(公告)号：US06275472B1

公开(公告)日：2001-08-14

申请号：US09016457

申请日：1998-01-30

申请人： Tomoyuki Yamaguchi ,  Naoki Aihara

发明人： Tomoyuki Yamaguchi ,  Naoki Aihara

IPC分类号： H04L1226

CPC分类号： H04L43/0847 ,  H04L43/16 ,  H04L49/205 ,  H04L49/3009 ,  H04L49/552 ,  H04L69/40 ,  H04L2012/5647 ,  H04L2012/5673 ,  H04L2012/5674

摘要： An apparatus for pass control of transmission cells for preventing cells having headers including a specific pattern of multi-bit error from being erroneously transmitted. The pass control apparatus is operated by a method comprising (i) a step of monitoring a communication quality of each received frame; (ii) a step of temporarily buffering one monitored frame's worth of cells for each frame; (iii) a step of determining whether or not the communication quality of the monitored frame exceeds a predetermined threshold level; and (iv) a step of erasing all of the cells including one-bit error and multi-bit error in their headers from one frame's worth of buffered cells when the communication quality deteriorates exceeding the predetermined threshold level, while passing the buffered cells as they are when it does not exceed the threshold level.

摘要翻译： 一种传输单元的通过控制装置，用于防止具有包含特定多比特错误模式的头部的小区被错误地发送。 通过控制装置通过以下方法操作：（i）监视每个接收帧的通信质量的步骤; （ii）为每个帧临时缓冲一个被监视帧的小区的步骤; （iii）确定被监视帧的通信质量是否超过预定阈值水平的步骤; 以及（iv）当通信质量恶化超过预定阈值水平时，同时通过缓冲的小区，从一帧的缓冲单元的头部中删除包括一位错误和多位错误的所有单元的步骤， 当它不超过阈值水平时。

公开(公告)号：US06046996A

公开(公告)日：2000-04-04

申请号：US713239

申请日：1996-09-12

申请人： Tadashi Hoshino ,  Naoki Aihara ,  Takashi Tabu ,  Tomoyuki Yamaguchi

发明人： Tadashi Hoshino ,  Naoki Aihara ,  Takashi Tabu ,  Tomoyuki Yamaguchi

IPC分类号： H04Q3/00 ,  H04L12/947 ,  H04L12/951 ,  H04Q11/04 ,  H04L12/56

CPC分类号： H04L49/309 ,  H04L49/3009 ,  H04Q11/0478

摘要： An identifier translation apparatus is provided that does not require a prohibitively large memory capacity and that is simple in construction and capable of increasing the speed of processing. Using an address consisting of a VPI and the high-order 6 bits of a VCI, a first-stage table is read to retrieve a block number, and using an address consisting of the retrieved block number and the low-order 6 bits of the VCI, a second-stage table is read to retrieve a routing tag. The routing tag is then appended to a cell.

摘要翻译： 提供了一种标识符转换装置，其不需要超大的存储容量，并且结构简单并且能够提高处理速度。 使用由VPI和VCI的高6位组成的地址，读取第一级表以检索块号，并使用由检索到的块号和低位6位组成的地址 VCI读取第二级表以检索路由标签。 然后将路由标签附加到单元。

公开(公告)号：US20130028890A1

公开(公告)日：2013-01-31

申请号：US13617027

申请日：2012-09-14

申请人： Shimon Sakaguchi ,  Keiji Hirota ,  Tomoyuki Yamaguchi

发明人： Shimon Sakaguchi ,  Keiji Hirota ,  Tomoyuki Yamaguchi

IPC分类号： A61K39/395 ,  A61P37/04 ,  A61P35/00

CPC分类号： C07K16/28 ,  A61K2039/505 ,  G01N33/56972

摘要： An object of the present invention is to provide a technique to distinguish between Treg cells and activated T cells in a live state. Another object of the present invention is to provide a pharmaceutical composition for immunostimulation that can reduce the number of Treg cells in vivo and effectively express the immune response of activated T cells.In the method of the present invention, Treg cells are detected from test cells containing (i) regulatory T cells and (ii) at least one type of cell selected from the group consisting of naive T cells and activated T cells, wherein expressions of folate receptor 4 on the surfaces of cells are measured and Treg cells are detected using the expressions as an indicator. The present invention uses anti-folate receptor 4 antibody or folate receptor 4-binding fragment as an active ingredient contained in a pharmaceutical composition for immunostimulation.

摘要翻译： 本发明的目的是提供一种在活体状态下区分Treg细胞和活化的T细胞的技术。 本发明的另一个目的是提供用于免疫刺激的药物组合物，其可以减少体内Treg细胞的数量并有效表达活化的T细胞的免疫应答。 在本发明的方法中，从含有（i）调节性T细胞的试验细胞和（ii）至少一种选自初始T细胞和活化的T细胞的细胞中检测Treg细胞，其中叶酸的表达 测定细胞表面的受体4，使用表达作为指标检测Treg细胞。 本发明使用抗叶酸受体4抗体或叶酸受体4结合片段作为用于免疫刺激的药物组合物中含有的活性成分。

公开(公告)号：US20100122360A1

公开(公告)日：2010-05-13

申请号：US12583559

申请日：2009-08-21

申请人： Hiromitsu Nakauchi ,  Toshihiro Kobayashi ,  Younsu Lee ,  Joichi Usui ,  Tomoyuki Yamaguchi ,  Sanae Hamanaka

发明人： Hiromitsu Nakauchi ,  Toshihiro Kobayashi ,  Younsu Lee ,  Joichi Usui ,  Tomoyuki Yamaguchi ,  Sanae Hamanaka

IPC分类号： A01K67/00 ,  C12N5/07 ,  A01N1/02

CPC分类号： A01K67/0271 ,  A01K2207/20 ,  A61L27/3834

摘要： An object of the present invention is to produce a mammalian organ having a complicated cellular composition composed of multiple kinds of cells, such as kidney, pancreas, thymus and hair, in the living body of a non-human animal. The inventors of the present invention applied the chimeric animal assay described above, to a novel solid organ production method. More specifically, the inventors has shown that a model mouse which is deficient of kidney, pancreas, thymus or hair due to the dysfunction of the metanephric mesenchyme that is differentiated into most of an adult kidney, is rescued by blastocyst complementation by the chimeric animal assay, and whereby a kidney, a pancreas, thymus or hair can be newly produced.

摘要翻译： 本发明的目的是在非人动物的活体中制备由多种细胞如肾，胰腺，胸腺和毛发组成的细胞组成复杂的哺乳动物器官。 本发明的发明人将上述嵌合动物实验应用于新型的固体器官生产方法。 更具体地，本发明人已经表明，由分化成大部分成年肾脏的间质间质的功能障碍引起的肾，胰腺，胸腺或毛发缺陷的模型小鼠通过嵌合动物试验通过囊胚互补来拯救 ，由此可以新生产肾，胰腺，胸腺或毛发。

公开(公告)号：US20070062919A1

公开(公告)日：2007-03-22

申请号：US11598708

申请日：2006-11-14

申请人： Shiro Hamada ,  Jiro Yamamoto ,  Tomoyuki Yamaguchi

发明人： Shiro Hamada ,  Jiro Yamamoto ,  Tomoyuki Yamaguchi

IPC分类号： B23K26/38 ,  B23K26/06

CPC分类号： B23K26/0652 ,  B23K26/0622 ,  B23K26/0626 ,  B23K26/0648 ,  B23K26/066 ,  B23K26/0732 ,  B23K26/082 ,  B23K26/0853 ,  B23K26/364 ,  B23K26/382 ,  B23K26/40 ,  B23K26/60 ,  B23K2101/40 ,  B23K2103/42 ,  B23K2103/50

摘要： Laser beam is irradiated to a surface of a processing target after reforming a cross section of the laser beam with a mask having a pierced hole by concentrating the laser beam passing through the pierced hole by a lens to form an image of the pierced hole of the mask on the surface of the processing target. The laser beam passing through the lens is scanned to move an irradiating position of the laser beam on the surface of the processing target, and the image of the pierced hole of the mask is formed on the surface of the processing target during the scanning for processing the processing target. A high quality laser process can be carried out.

摘要翻译： 在通过使透镜穿过穿孔的激光束聚焦以形成透镜的穿孔的图像之后，通过具有穿孔的掩模对激光束的横截面进行重整后，将激光束照射到处理对象的表面 掩模在加工对象的表面上。 扫描通过透镜的激光束，将激光束的照射位置移动到处理对象物的表面，并且在扫描处理期间将掩模的穿孔的图像形成在处理对象的表面上 处理目标。 可以进行高质量的激光加工。

公开(公告)号：US20060077898A1

公开(公告)日：2006-04-13

申请号：US11284669

申请日：2005-11-22

申请人： Tomoyuki Yamaguchi ,  Shinji Wakasa ,  Yasuyuki Mitsumori

发明人： Tomoyuki Yamaguchi ,  Shinji Wakasa ,  Yasuyuki Mitsumori

IPC分类号： H04J1/16

CPC分类号： H04L47/39 ,  H04L45/22 ,  H04L47/10 ,  H04L47/18

摘要： A transmission base flow control device performs data transmission/reception based on a packet form between a transmission device and a reception device having a redundant structure by utilizing a credit value to carry out a flow control of a credit base on a flow basis. The transmission base flow control device includes: a first credit counter, which is shared by an active system and a preparatory system of the reception device, for managing the credit value of the active system; a second credit counter and a third credit counter for counting the credit values for each system of the active system and the preparatory system of the reception device; a differential counter for holding a difference between the credit value counted by the second credit counter and the credit value counted by the third credit counter; and a control unit for matching, according to the difference held by the differential counter, the credit values of the first credit counter and the second credit counter or the credit values of the first credit counter and the third credit counter with a credit value corresponding to the reception device of a new active system after switching the system of the reception device.

摘要翻译： 发送基站流量控制装置通过利用信用值在发送装置与具有冗余结构的接收装置之间基于分组形式进行数据发送/接收，以流量为基础进行信用卡的流量控制。 传输基本流量控制装置包括：由活动系统共享的第一信用计数器和接收装置的预备系统，用于管理活动系统的信用值; 第二信用计数器和用于对活动系统的每个系统和接收装置的预备系统的信用值进行计数的第三信用计数器; 用于保存由第二信用计数器计数的信用值与由第三信用计数器计数的信用值之间的差的差分计数器; 以及控制单元，用于根据差分计数器所保持的差异，匹配第一信用计数器和第二信用计数器的信用值或第一信用计数器和第三信用计数器的信用值，其信用值对应于 在切换接收设备的系统之后的新的主动系统的接收设备。