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公开(公告)号：US20100076554A1
公开(公告)日：2010-03-25
申请号：US12628344
申请日：2009-12-01
CPC分类号： A61F2/1624 , A61F2/1618 , A61F2/1627 , A61F2/1635 , A61L27/18 , A61L2430/16 , G02B1/043 , G02C7/06 , G02C2202/14 , C08L83/04
摘要： The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.
摘要翻译： 本发明涉及新型眼内透镜。 透镜能够对其光学性能进行术后调整，包括从单焦点透镜转换为多焦点透镜。
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公开(公告)号：US07988285B2
公开(公告)日：2011-08-02
申请号：US12628344
申请日：2009-12-01
CPC分类号： A61F2/1624 , A61F2/1618 , A61F2/1627 , A61F2/1635 , A61L27/18 , A61L2430/16 , G02B1/043 , G02C7/06 , G02C2202/14 , C08L83/04
摘要： The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.
摘要翻译： 本发明涉及新型眼内透镜。 透镜能够对其光学性能进行术后调整，包括从单焦点透镜转换为多焦点透镜。
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公开(公告)号：US07281795B2
公开(公告)日：2007-10-16
申请号：US11083794
申请日：2005-03-18
CPC分类号： A61F2/1624 , A61F2/1618 , A61F2/1627 , A61F2/1635 , A61L27/18 , A61L2430/16 , G02B1/043 , G02C7/06 , G02C2202/14 , C08L83/04
摘要： The invention relates to novel intraocular lenses. The lenses are capable of post-operative adjustment of their optical properties, including conversion from single focal lenses to multifocal lenses.
摘要翻译： 本发明涉及新型眼内透镜。 透镜能够对其光学性能进行术后调整，包括从单焦点透镜转换为多焦点透镜。
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公开(公告)号：US07241009B2
公开(公告)日：2007-07-10
申请号：US10871686
申请日：2004-06-17
IPC分类号： G02C7/02
CPC分类号： A61F2/1613 , A61F2/16 , A61F2/1627 , A61F2/1635 , A61F2002/1699 , B29D11/00442 , B29D11/023 , G02B1/043 , G02C2202/14 , C08L83/04
摘要： Methods and materials are disclosed for the production of optical elements, in particular intraocular lenses (IOL) that incorporate any amount (0 to 99%) of refraction and/or shape modulating compound into a substantially crosslinked first polymeric matrix. The materials produced according to the inventive methods exhibit certain rheological parameters useful in defining medical lenses. These medical lenses have the ability to change their refractive power via changing the refractive index and/or by altering the shape by stimulus induced polymerization.
摘要翻译： 公开了用于生产光学元件的方法和材料，特别是将任何量（0至99％）的折射和/或形状调节化合物掺入基本交联的第一聚合物基质中的眼内透镜（IOL）。 根据本发明方法生产的材料表现出用于定义医用透镜的某些流变参数。 这些医用透镜具有通过改变折射率和/或通过刺激诱导聚合来改变形状而改变它们的屈光力的能力。
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5.发明授权Initiator and ultraviolet absorber blends for changing lens power by ultraviolet light 有权用于通过紫外线改变透镜功率的引发剂和紫外线吸收剂混合物公开(公告)号：US07560499B2
公开(公告)日：2009-07-14
申请号：US11149837
申请日：2005-06-10
CPC分类号： C08G77/388 , A61L27/14 , A61L27/50 , A61L2430/16 , C08F2/50 , C08G77/38 , C08K5/3475 , C08K5/5419 , C08L83/06 , C08L83/08 , C08L83/14 , G02C2202/14 , C08L83/00 , C08L2666/14
摘要： Novel blends of photo-initiators and photo-absorbers are disclosed. By the proper selection of the type and amount of absorber and initiator used in a composition, it is possible to regulate the conditions under which photo-induced reactions occur. In a specific embodiment, blends of UV initiators and photoabsorbers are used to control the conditions under which UV initiated polymerization occurs.
摘要翻译： 公开了光引发剂和光吸收剂的新型共混物。 通过适当选择组合物中使用的吸收剂和引发剂的类型和量，可以调节光诱导反应发生的条件。 在一个具体实施方案中，UV引发剂和光吸收剂的共混物用于控制发生UV引发聚合的条件。
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公开(公告)号：US06851804B2
公开(公告)日：2005-02-08
申请号：US10324540
申请日：2002-12-19
IPC分类号： G02C7/02 , A61F2/16 , A61L27/48 , A61L27/50 , B29D11/00 , C08F2/48 , C08F2/50 , C08F290/06 , C08K5/3475 , G02B1/04 , G02C7/04 , C08K5/34 , A61F2/14 , G02C7/00
CPC分类号： C08F2/50 , A61L27/48 , A61L27/50 , C08F290/068 , G02B1/043 , G02C2202/14
摘要： The invention relates to optical elements whose optical properties can be repeatedly adjusted over time. Through the use of modifying compositions capable of stimulus induced polymerization coupled with a blend of stimulus absorbers and initiators, it is possible to repeatedly adjust the optical properties of the element by exposing the lens to a stimulus which exceeds the absorption capacity of the stimulus absorber.
摘要翻译： 本发明涉及光学特性随时间反复调整的光学元件。 通过使用能够与刺激吸收剂和引发剂共混物进行刺激诱导聚合的改性组合物，可以通过将镜片暴露于超过刺激吸收剂的吸收能力的刺激物来重复地调节元件的光学性质。
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公开(公告)号：US09713527B2
公开(公告)日：2017-07-25
申请号：US11489847
申请日：2006-07-20
申请人： Okihiro Nishi , Kayo Nishi , Shiao H. Chang , Jerry Kaeni
发明人： Okihiro Nishi , Kayo Nishi , Shiao H. Chang , Jerry Kaeni
CPC分类号： A61F2/1648 , A61F2/1613 , A61F2/1627 , A61F2/1635 , A61F9/0017 , A61F9/007 , A61F2002/1699 , A61F2002/30581 , A61F2002/30583 , A61F2210/0085 , A61L27/18 , A61L27/50 , A61L2430/16 , C08L83/04
摘要： The invention relates to a multi-lens intraocular lens system having an accommodation material between the lenses. The system comprises an posterior lens attached to the posterior surface of the capsular bag and an anterior lens attached to the anterior surface of the capsular bag. The anterior and posterior lenses have different optical properties providing different degrees and types of correction. An accommodation material is place between the anterior and posterior lenses. The accommodation material may comprise of one or more macromers, which, when polymerized, adjust the properties of the accommodation material.
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公开(公告)号：US5674284A
公开(公告)日：1997-10-07
申请号：US605454
申请日：1996-02-26
CPC分类号： B29D11/023 , B29C43/02 , A61F2002/1683 , B29C2793/009 , B29C43/00 , B29K2033/12 , B29K2105/255 , B29K2995/0053 , B29K2995/0064 , B29L2011/0016 , Y10S425/808
摘要： The polymethyl methacrylate (PMMA) or copolymer thereof used to produce one-piece intraocular lenses is modified by a compression molding process to produce a much tougher material with improved mechanical properties. The process takes material in rod form and compresses into lens blanks. The molded lens blanks receive little or no compression strain in the center 4 mm optic zone. The compression is limited to the periphery region outside the center 4 mm zone. The intraocular lens fabricated from the molded lens blank exhibits greatly increased haptic mechanical properties and resistance to breakage.
摘要翻译： 用于制造单件眼内透镜的聚甲基丙烯酸甲酯（PMMA）或其共聚物通过压缩模塑方法进行改性，以产生具有改善的机械性能的更坚韧的材料。 该过程采用棒状材料并压缩成镜片坯料。 模制的透镜毛坯在中心4 mm光学区域几乎没有受到压缩应变。 压缩限制在中心4 mm区域外的周边区域。 由模制的透镜毛坯制造的眼内透镜显示出大大增加的触觉机械性能和抗断裂性。
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9.发明授权Method for making novel compositions capable of post fabrication modification 有权制备能够进行后制造改性的新型组合物的方法公开(公告)号：US08361353B2
公开(公告)日：2013-01-29
申请号：US11486615
申请日：2006-07-14
申请人： Axel Brait , Shiao H. Chang , Patrick Case
发明人： Axel Brait , Shiao H. Chang , Patrick Case
CPC分类号： B05D5/06 , A61F2/1627 , G02B1/041 , C08L83/04 , C08L79/00 , C08L33/08 , C08L33/10 , C08L85/02
摘要： The invention relates to a novel method for preparing materials whose properties can be manipulated after fabrication. In this process, a base material is created in a manner that provides spaces or voids which can then be filled with a modifying composition. The method is particularly useful in the manufacture of light adjustable optical elements such as intraocular lenses.
摘要翻译： 本发明涉及一种制备材料的新方法，其制造后可以操作其性能。 在该方法中，以提供空间或空隙的方式产生基材，然后可以用改性组合物填充基材。 该方法在制造可调光学元件如眼内透镜中特别有用。
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10.发明申请Method for improved retinal safety using the light adjustable lens (LAL) 审中-公开使用光调透镜（LAL）改善视网膜安全的方法公开(公告)号：US20080027537A1
公开(公告)日：2008-01-31
申请号：US11493358
申请日：2006-07-26
IPC分类号： A61F2/16
CPC分类号： A61F2/1635 , A61F2/1618 , A61L27/50 , A61L2430/16 , G02C2202/14
摘要： Embodiments of the invention involve intraocular lenses that are light adjustable to change a focal length of the lens after it has been implanted into a person or animal. The lens includes a layer of UV absorbent material located on a rear side, which is the side facing a retina. The lens may comprise a UV reducing rim that surrounds a peripheral portion of the lens, and reduces or blocks UV light from striking the retina.
摘要翻译： 本发明的实施例涉及可调节眼睛的眼内透镜，以便在将晶状体植入人或动物之后改变透镜的焦距。 透镜包括位于后侧的UV吸收材料层，其是面向视网膜的一侧。 透镜可以包括围绕透镜的周边部分的紫外线减少边缘，并且减少或阻挡来自打击视网膜的紫外光。
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