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公开(公告)号：US08986209B2
公开(公告)日：2015-03-24
申请号：US13549313
申请日：2012-07-13
IPC分类号： A61B5/05 , A61B5/145 , A61B5/00 , A61B5/1486 , A61B5/1495
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/0031 , A61B5/14546 , A61B5/14865 , A61B5/1495 , A61B5/4839 , A61B5/6833 , A61B5/6848 , A61B5/743 , A61B2560/0223 , A61B2560/0252 , A61B2560/04 , A61B2562/085
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
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公开(公告)号：US07774145B2
公开(公告)日：2010-08-10
申请号：US11334876
申请日：2006-01-18
IPC分类号： G01N33/50
CPC分类号： A61B5/14532 , A61B5/0002 , A61B5/0031 , A61B5/14546 , A61B5/14865 , A61B5/1495 , A61B5/4839 , A61B5/6833 , A61B5/6848 , A61B5/743 , A61B2560/0223 , A61B2560/0252 , A61B2560/04 , A61B2562/085
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host. In some embodiments, a device is provided for monitoring glucose concentration in a host, including a continuous glucose sensor and an integrated receiver including a single point glucose monitor. In some embodiments, a computer system is provided that determines a rate of change of continuous analyte sensor data.
摘要翻译： 本发明一般涉及用于测量宿主中分析物的系统和方法。 更具体地说，本发明涉及用于经皮测量宿主中的葡萄糖的系统和方法。 在一些实施例中，提供了一种用于监测主机中的葡萄糖浓度的装置，包括连续葡萄糖传感器和包括单点葡萄糖监测器的集成接收器。 在一些实施例中，提供了确定连续分析物传感器数据的变化速率的计算机系统。
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公开(公告)号：US08788007B2
公开(公告)日：2014-07-22
申请号：US13415721
申请日：2012-03-08
IPC分类号： A61B5/05
CPC分类号： A61B5/14865 , A61B5/0002 , A61B5/14532 , A61B5/14546 , A61B5/1495 , A61B5/6833 , A61B5/6848 , A61B5/6849 , A61B5/726 , A61B5/743 , A61B2560/0223
摘要： The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
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公开(公告)号：US20100198036A1
公开(公告)日：2010-08-05
申请号：US12760432
申请日：2010-04-14
申请人： Apurv Ullas Kamath , Peter C. Simpson , James H. Brauker , Paul V. Goode, JR. , Mark Brister , Paul V. Neale , Sean Saint
发明人： Apurv Ullas Kamath , Peter C. Simpson , James H. Brauker , Paul V. Goode, JR. , Mark Brister , Paul V. Neale , Sean Saint
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/7203 , A61B5/742 , A61B2560/0223 , B33Y70/00 , B33Y80/00
摘要： Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
摘要翻译： 本文公开了用于校准连续分析物传感器（例如连续葡萄糖传感器）的系统和方法。 一个这样的系统利用一个或多个电极来测量另外的分析物。 这样的测量可以提供用于校准传感器的基线或灵敏度测量。 此外，可以使用基线和/或灵敏度测量来触发诸如数字数字滤波或暂停显示数据的事件。
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公开(公告)号：US20100198035A1
公开(公告)日：2010-08-05
申请号：US12760358
申请日：2010-04-14
申请人： Apurv Ullas Kamath , Peter C. Simpson , James H. Brauker , Paul V. Goode, JR. , Mark Brister , Paul V. Neale , Sean Saint
发明人： Apurv Ullas Kamath , Peter C. Simpson , James H. Brauker , Paul V. Goode, JR. , Mark Brister , Paul V. Neale , Sean Saint
IPC分类号： A61B5/145
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/1495 , A61B5/7203 , A61B5/742 , A61B2560/0223 , B33Y70/00 , B33Y80/00
摘要： Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
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公开(公告)号：US09078608B2
公开(公告)日：2015-07-14
申请号：US13548627
申请日：2012-07-13
IPC分类号： A61B5/145 , A61B5/1473 , A61B5/00 , A61B5/1486 , A61B5/1495
CPC分类号： A61B5/1495 , A61B5/0031 , A61B5/14503 , A61B5/1451 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/14735 , A61B5/1486 , A61B5/14865 , A61B2560/0223
摘要： Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
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公开(公告)号：US08676287B2
公开(公告)日：2014-03-18
申请号：US12636584
申请日：2009-12-11
IPC分类号： A61B5/05
CPC分类号： A61B5/1495 , A61B5/14532 , A61B2560/0223 , G06F19/00
摘要： Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
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8.发明申请SYSTEM AND METHODS FOR PROCESSING ANALYTE SENSOR DATA FOR SENSOR CALIBRATION 有权用于处理用于传感器校准的分析仪传感器数据的系统和方法公开(公告)号：US20130060112A1
公开(公告)日：2013-03-07
申请号：US13607162
申请日：2012-09-07
IPC分类号： A61B5/1495
CPC分类号： A61B5/1495 , A61B5/0031 , A61B5/14503 , A61B5/1451 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/14735 , A61B5/1486 , A61B5/14865 , A61B2560/0223
摘要： Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
摘要翻译： 公开了用于处理传感器分析物数据的系统和方法，包括启动校准，更新校准，评估参考和传感器分析物数据的临床可接受性，以及评估传感器校准的质量。 可以使用一个或多个匹配的传感器和参考分析物数据对的校准集来校准传感器。 在分析物传感器插入之前进行台式测试产生的参考数据可用于提供传感器数据的初始校准。 植入用户的短期连续分析物传感器的参考数据可用于初始校准或更新来自长期连续分析物传感器的传感器数据。
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公开(公告)号：US20100168546A1
公开(公告)日：2010-07-01
申请号：US12683755
申请日：2010-01-07
IPC分类号： A61B5/1495 , A61B5/145
CPC分类号： A61B5/1495 , A61B5/0031 , A61B5/14503 , A61B5/1451 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/1473 , A61B5/14735 , A61B5/1486 , A61B5/14865 , A61B2560/0223
摘要： Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
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公开(公告)号：US08657745B2
公开(公告)日：2014-02-25
申请号：US12252967
申请日：2008-10-16
申请人： James H. Brauker , Victoria E. Carr-Brendel , Paul V. Goode , Apurv Ullas Kamath , James Patrick Thrower , Ben Xavier
发明人： James H. Brauker , Victoria E. Carr-Brendel , Paul V. Goode , Apurv Ullas Kamath , James Patrick Thrower , Ben Xavier
CPC分类号： A61B5/14532 , A61B5/145 , A61B5/14503 , A61B5/1451 , A61B5/1468 , A61B5/1473 , A61B5/1486 , A61B5/14865 , A61B5/1495 , A61B5/7257 , A61B5/726 , A61B5/7264 , A61B5/7275 , A61B5/742 , A61B5/7455 , A61B5/746 , A61B5/7475 , A61M5/1723 , G06F19/00 , Y02A90/22 , Y02A90/26
摘要： Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.
摘要翻译： 用于动态和智能地估计来自连续分析物传感器的分析物数据的系统和方法，包括接收数据流，选择多种算法中的一种，以及采用所选择的算法来估计分析物值。 附加数据处理包括评估所选择的估计算法，基于统计学，临床或生理参数分析估计分析物值的变化，将估计的分析物值与相应的测量分析物值进行比较，以及向用户提供输出。 估计可用于补偿时间滞后，匹配传感器数据与相应的参考数据，警告即将到来的临床风险，替换错误的传感器数据信号，并提供更及时的分析物信息，鼓励主动行为和抢占临床风险。
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