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公开(公告)号：US07960599B2
公开(公告)日：2011-06-14
申请号：US10542167
申请日：2004-01-13
IPC分类号： C07C5/22
CPC分类号： C07C67/333 , C07C6/04 , C07C11/02 , C07C11/167 , C07C51/353 , C07C2531/22 , C07C2531/24 , C11C3/14 , C12P5/026 , C12P7/62 , C12P7/6409 , C12P7/649 , Y02E50/13 , C07C57/03 , C07C69/533
摘要： A process for producing industrially important chemicals from renewable resources is disclosed. This “biobased” process employs readily available, renewable resources comprising fatty acids rather than exploiting fossil sources, such as coal and petroleum. In one embodiment of the process 1-octene, along with methyl-9-decenoate and butadiene, is produced from linoleic acid via an enzymemediated isomerization reaction, followed by a metathesis reaction with ethylene. Linoleic acid can be isolated from vegetable oils, such as soybean oil.
摘要翻译： 公开了从可再生资源生产工业上重要的化学品的过程。 这种“生物基”方法采用包含脂肪酸的易于获得的可再生资源，而不是利用化石源，如煤和石油。 在该方法的一个实施方案中，1-辛烯以及9-癸烯酸甲酯和丁二烯通过酶促异构化反应由亚油酸生产，随后与乙烯进行复分解反应。 亚油酸可以从植物油中分离出来，如大豆油。
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2.发明授权公开(公告)号：US08685118B2
公开(公告)日：2014-04-01
申请号：US11795052
申请日：2006-01-10
摘要： A wax comprises a metathesis product and/or a product that resembles, at least in part, a product which may be formed from a metathesis reaction. The wax may be used to form articles, for example, candles (container candles, votive candles, and/or a pillar candles), crayons, fire logs, or tarts. The wax commonly includes other components in addition to the metathesis product.
摘要翻译： 蜡包括复分解产物和/或类似于至少部分类似于可由复分解反应形成的产物的产物。 蜡可以用于形成制品，例如蜡烛（容器蜡烛，献色蜡烛和/或支柱蜡烛），蜡笔，火记录或挞。 除了复分解产物之外，蜡通常还包括其它组分。
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3.发明申请公开(公告)号：US20090217568A1
公开(公告)日：2009-09-03
申请号：US11795052
申请日：2006-01-10
IPC分类号： C11C5/00
摘要： A wax comprises a metathesis product and/or a product that resembles, at least in part, a product which may be formed from a metathesis reaction. The wax may be used to form articles, for example, candles (container candles, votive candles, and/or a pillar candles), crayons, fire logs, or tarts. The wax commonly includes other components in addition to the metathesis product.
摘要翻译： 蜡包括复分解产物和/或类似于至少部分类似于可由复分解反应形成的产物的产物。 蜡可以用于形成制品，例如蜡烛（容器蜡烛，献色蜡烛和/或支柱蜡烛），蜡笔，火记录或挞。 除了复分解产物之外，蜡通常还包括其它组分。
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4.发明授权Polypeptides and biosynthetic pathways for the production of monatin and its precursors 有权用于生产莫纳甜及其前体的多肽和生物合成途径公开(公告)号：US07572607B2
公开(公告)日：2009-08-11
申请号：US11114922
申请日：2005-04-26
申请人： Paula M. Hicks , Sara C. McFarlan , Timothy W. Abraham , Douglas C. Cameron , James R. Millis , John Rosazza , Lishan Zhao , David Paul Weiner
发明人： Paula M. Hicks , Sara C. McFarlan , Timothy W. Abraham , Douglas C. Cameron , James R. Millis , John Rosazza , Lishan Zhao , David Paul Weiner
摘要： Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions.
摘要翻译： 提供可用于从葡萄糖，色氨酸，吲哚-3-乳酸，吲哚-3-丙酮酸和2-羟基2-（吲哚-3-基甲基）-4-酮戊二酸制备莫纳甜的方法和组合物 。 还公开了制备吲哚-3-丙酮酸和2-羟基2-（吲哚-3-基甲基）-4-酮戊二酸中间体的方法。 提供的组合物包括核酸分子，多肽，化学结构和细胞。 方法包括体外和体内过程，体外方法包括化学反应。
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公开(公告)号：US08435765B2
公开(公告)日：2013-05-07
申请号：US12124014
申请日：2008-05-20
申请人： Timothy W. Abraham , Douglas C. Cameron , Paula M. Hicks , Sara C. McFarlan , James R. Millis , John Rosazza , David P. Weiner , Lishan Zhao
发明人： Timothy W. Abraham , Douglas C. Cameron , Paula M. Hicks , Sara C. McFarlan , James R. Millis , John Rosazza , David P. Weiner , Lishan Zhao
CPC分类号： C12P17/10 , C12N9/0006 , C12N9/0014 , C12N9/0016 , C12N9/1096 , C12N15/52
摘要： Methods and compositions that can be used to make monatin from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions.
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6.发明申请公开(公告)号：US20090130285A1
公开(公告)日：2009-05-21
申请号：US12271655
申请日：2008-11-14
申请人： Timothy W. Abraham , Douglas C. Cameron , Melanie J. Goulson , Paula M. Hicks , Michael G. Lindley , Sara C. McFarlan , James R. Millis , John Rosazza , Lishan Zhao , David P. Weiner
发明人： Timothy W. Abraham , Douglas C. Cameron , Melanie J. Goulson , Paula M. Hicks , Michael G. Lindley , Sara C. McFarlan , James R. Millis , John Rosazza , Lishan Zhao , David P. Weiner
IPC分类号： A23L1/236
摘要： The present invention relates to novel beverage compositions comprising monatin and methods for making such compositions. The present invention also relates to beverage compositions comprising specific monatin stereoisomers, specific blends of monatin stereoisomers, and/or monatin produced via a biosynthetic pathway in vivo (e.g., inside cells) or in vitro.
摘要翻译： 本发明涉及包含莫纳甜的新型饮料组合物和制备这种组合物的方法。 本发明还涉及包含特定莫纳甜立体异构体，莫纳甜立体异构体的特异性共混物和/或通过体内生物合成途径（例如细胞内）或体外产生的莫纳甜的饮料组合物。
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公开(公告)号：US08440783B2
公开(公告)日：2013-05-14
申请号：US12226696
申请日：2007-04-27
申请人： Timothy W. Abraham , Jeff Malsam , Xiuguang A. Guo , Milhail Ionescu , Ivan J. Javni , Zoran S. Petrovic
发明人： Timothy W. Abraham , Jeff Malsam , Xiuguang A. Guo , Milhail Ionescu , Ivan J. Javni , Zoran S. Petrovic
IPC分类号： C08G69/28
CPC分类号： C08G18/36 , C08G18/7621 , C08G2101/00
摘要： Enhanced oligomeric polyols are reported. The enhanced oligomeric polyols may be prepared by a method comprising the steps of: (a) providing an oligomeric polyol that comprises at least one glycerol fatty acid ester having at least one glycerol fatty acid ester bond; wherein at least 5% of the ethyldenyl groups (*C═C*) in the glycerol fatty acid ester are substituted with a bonding structure selected from the group consisting of: C-*C—C*-C; O-*C—C*-O; C=*C—C*-C, and mixtures thereof, where * is used to denote the original carbon atoms in the ethylidenyl group; and (b) cleaving at least a portion of the glycerol fatty acid ester bonds to form the enhanced oligomeric polyol. The enhanced oligomeric polyols are useful in making polymers such as polyurethanes.
摘要翻译： 报道了增强低聚多元醇。 增强的低聚多元醇可以通过包括以下步骤的方法制备：（a）提供包含至少一种具有至少一种甘油脂肪酸酯键的甘油脂肪酸酯的低聚多元醇; 其中所述甘油脂肪酸酯中的至少5％的乙烯基（* C = C *）被选自以下的键合结构取代：C- * C-C * -C; O- * C-C * -O; C = * C-C * -C及其混合物，其中*用于表示亚乙基中的原始碳原子; 和（b）切割甘油脂肪酸酯键的至少一部分以形成增强的低聚多元醇。 增强的低聚多元醇可用于制备聚合物如聚氨酯。
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8.发明申请OLIGOMERIC POLYOLS FROM PALM-BASED OILS AND POLYURETHANE COMPOSITIONS MADE THEREFROM 审中-公开来自棕榈油的低聚多元醇和其中的聚氨酯组合物公开(公告)号：US20100261805A1
公开(公告)日：2010-10-14
申请号：US12225650
申请日：2007-03-27
IPC分类号： C08G18/32 , C07C29/151
CPC分类号： C08G18/36 , C08G18/6696 , C08G2101/0008 , C08G2101/0083
摘要： The invention relates to oligomeric polyols that are made from palm-based oils and to polyurethane compositions comprising the oligomeric palm-based polyols. Oligomeric polyols of the invention comprise a ring-opened and oligomerized epoxidized palm-based oil composition comprising about 40% wt. or greater oligomers, a hydroxyl number of about 65 or less, a number average hydroxyl functionality (fn) of about 2.5 or less, and a viscosity at 25° C. of about 4 Pa-s or less.
摘要翻译： 本发明涉及由棕榈油和由低聚棕榈基多元醇组成的聚氨酯组合物制成的低聚多元醇。 本发明的低聚多元醇包含开环和低聚的环氧化棕榈油组合物，其包含约40重量％ 或更大的低聚物，约65或更小的羟值，约2.5或更小的数均羟基官能度（fn）和约25Pa的粘度约4Pa·s以下。
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公开(公告)号：US08338145B2
公开(公告)日：2012-12-25
申请号：US12507008
申请日：2009-07-21
CPC分类号： C07C67/30 , C07C51/347 , C07C51/377 , C07C67/03 , C07C67/08 , C07C67/31 , C07C67/327 , C12P7/42 , C12P7/52 , C07C57/04 , C07C69/675 , C07C69/708 , C07C69/54
摘要： Preparation of derivatives of β-hydroxycarboxylic acid, including β-hydroxycarboxylic acid esters, α,β-unsaturated carboxylic acid, esters of α,β-unsaturated carboxylic acid, and alkoxy derivatives.
摘要翻译： α-羟基羧酸衍生物的制备，包括α-羟基羧酸酯，α，β-不饱和羧酸，α，β-不饱和羧酸的酯和烷氧基衍生物。
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公开(公告)号：US08206955B2
公开(公告)日：2012-06-26
申请号：US10969245
申请日：2004-10-21
申请人： Sara C. McFarlan , Paula M. Hicks , Mary Jo Zidwick , Fernando A. Sanchez-Riera , Douglas C. Cameron , Mervyn L. deSouza , John Rosazza , Steven J. Gort , Timothy W. Abraham
发明人： Sara C. McFarlan , Paula M. Hicks , Mary Jo Zidwick , Fernando A. Sanchez-Riera , Douglas C. Cameron , Mervyn L. deSouza , John Rosazza , Steven J. Gort , Timothy W. Abraham
CPC分类号： C12N9/88 , C12P17/10 , Y02P20/582
摘要： Methods and compositions that can be used to make monatin or salt thereof from glucose, tryptophan, indole-3-lactic acid, indole-3-pyruvate, and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid, are provided. Methods are also disclosed for producing the indole-3-pyruvate and 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid intermediates. Compositions provided include nucleic acid molecules, polypeptides, chemical structures, and cells. Methods include in vitro and in vivo processes, and the in vitro methods include chemical reactions.
摘要翻译： 可用于从葡萄糖，色氨酸，吲哚-3-乳酸，吲哚-3-丙酮酸和2-羟基2-（吲哚-3-基甲基）-4-酮戊二酸制备莫纳甜或其盐的方法和组合物 ，提供。 还公开了制备吲哚-3-丙酮酸和2-羟基2-（吲哚-3-基甲基）-4-酮戊二酸中间体的方法。 提供的组合物包括核酸分子，多肽，化学结构和细胞。 方法包括体外和体内过程，体外方法包括化学反应。
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