-
公开(公告)号：US08562973B2
公开(公告)日：2013-10-22
申请号：US13081422
申请日：2011-04-06
申请人： James W. Edinger , Steven Alan Fischkoff , Aleksandar Francki , Vladimir Jankovic , Bitao Liang , Philippe Martin , Cynthia Ray , Xiaokui Zhang
发明人： James W. Edinger , Steven Alan Fischkoff , Aleksandar Francki , Vladimir Jankovic , Bitao Liang , Philippe Martin , Cynthia Ray , Xiaokui Zhang
IPC分类号： C12C7/04
摘要： Methods of treating individuals having sarcoidosis or a sarcoidosis-related disease or disorder using placental cells are described. Also describe are kits comprising placental stem cells or a composition thereof that can be used in methods of treating sarcoidosis or a sarcoidosis-related disease or disorder.
摘要翻译： 描述了使用胎盘细胞治疗患有结节病或结节病相关疾病或病症的个体的方法。 还描述了可用于治疗结节病或结节病相关疾病或病症的方法中的胎盘干细胞或其组合物的试剂盒。
-
2.发明申请TREATMENT OF SPINAL CORD INJURY AND TRAUMATIC BRAIN INJURY USING AMNION DERIVED ADHERENT CELLS 审中-公开使用粘膜衍生的附属细胞治疗脊髓损伤和TRAUMATIC脑损伤公开(公告)号：US20120201787A1
公开(公告)日：2012-08-09
申请号：US13327289
申请日：2011-12-15
申请人： Stewart Abbot , James W. Edinger , Aleksandar Francki , Vladimir Jankovic , Aleksandr Kaplunovsky , Kristen Labazzo , Eric Law , Bitao Liang
发明人： Stewart Abbot , James W. Edinger , Aleksandar Francki , Vladimir Jankovic , Aleksandr Kaplunovsky , Kristen Labazzo , Eric Law , Bitao Liang
IPC分类号： A61K35/50 , A61P25/28 , A61P27/02 , A61P25/08 , A61P1/08 , A61P27/00 , A61P25/00 , A61P25/24
CPC分类号： C12N5/0605 , A61K35/50 , C12N5/0618 , C12N5/0636 , C12N5/0637 , C12N5/0639 , C12N5/0646 , C12N2502/025 , C12N2506/025
摘要： Provided herein are methods of treating spinal cord and traumatic brain injuries using cells from amnion, and populations of such cells, referred to herein as “amnion derived adherent cells” (“AMDACs”).
摘要翻译： 本文提供了使用羊膜细胞治疗脊髓和创伤性脑损伤的方法，以及这些细胞群，这里称为“羊膜来源的粘附细胞”（“AMDAC”）。
-
3.发明申请TREATMENT OF IMMUNE-RELATED DISEASES AND DISORDERS USING AMNION DERIVED ADHERENT CELLS 审中-公开使用粘膜衍生的附属细胞治疗免疫相关疾病和疾病公开(公告)号：US20120164114A1
公开(公告)日：2012-06-28
申请号：US13327315
申请日：2011-12-15
IPC分类号： A61K35/50 , A61P11/06 , A61P37/06 , A61P37/00 , A61P1/00 , A61P25/00 , A61P29/00 , A61P17/06 , A61P19/04 , A61P3/10 , A61P17/14 , A61P9/00 , A61P17/00 , A61P5/16 , A61P19/02 , A61P21/04 , A61P1/16 , A61P1/04 , A61P37/08
CPC分类号： C12N5/0605 , A61K35/50 , A61K2035/122 , C12N5/0668 , C12N2509/00
摘要： Provided herein are methods of using amnion derived adherent cells, and populations of, and compositions comprising, such cells, in the modulation of an immune response. In various embodiments, the immune response is graft-versus-host disease, an allergy, asthma, or an immune-related disease or disorder, e.g., an autoimmune disease.
摘要翻译： 本文提供了在调节免疫应答中使用羊膜来源的贴壁细胞的方法，以及包含这些细胞的群体和组合物的方法。 在各种实施方案中，免疫应答是移植物抗宿主病，过敏，哮喘或免疫相关疾病或病症，例如自身免疫性疾病。
-
4.发明申请TREATMENT OF SPINAL CORD INJURY AND TRAUMATIC BRAIN INJURY USING PLACENTAL STEM CELLS 审中-公开使用普通干细胞治疗脊髓损伤和TRAUMATIC脑损伤公开(公告)号：US20120156230A1
公开(公告)日：2012-06-21
申请号：US13327245
申请日：2011-12-15
申请人： Stewart Abbot , James W. Edinger , Aleksandar Francki , Vladimir Jankovic , Aleksandr Kaplunovsky , Kristen Labazzo , Eric Law , Bitao Liang
发明人： Stewart Abbot , James W. Edinger , Aleksandar Francki , Vladimir Jankovic , Aleksandr Kaplunovsky , Kristen Labazzo , Eric Law , Bitao Liang
CPC分类号： A61K35/50
摘要： Provided herein are methods of treatment of individuals having an injury to the central nervous system, such as a spinal cord injury or a traumatic brain injury, using placental stem cells and placental multipotent stem cells described herein, and populations of such placental cells.
摘要翻译： 本文提供了使用本文所述的胎盘干细胞和胎盘多能干细胞以及这种胎盘细胞群体治疗对中枢神经系统损伤的个体（例如脊髓损伤或创伤性脑损伤）的方法。
-
公开(公告)号：US20100124569A1
公开(公告)日：2010-05-20
申请号：US12622352
申请日：2009-11-19
申请人： Stewart ABBOT , James W. Edinger , Aleksandar Francki , Aleksandr Kaplunovsky , Vladimir Jankovic , Kristen Labazzo , Eric Law , Neerav D. Padliya , Jennifer Paredes , Jia-Lun Wang
发明人： Stewart ABBOT , James W. Edinger , Aleksandar Francki , Aleksandr Kaplunovsky , Vladimir Jankovic , Kristen Labazzo , Eric Law , Neerav D. Padliya , Jennifer Paredes , Jia-Lun Wang
CPC分类号： A61K35/50 , A61K35/12 , C12N5/0605
摘要： Provided herein are novel angiogenic cells from amnion, referred to as amnion derived adherent cells, and populations of, and compositions comprising, such cells. Further provided herein are methods of obtaining such cells and methods of using the cells in the treatment of individuals.
摘要翻译： 本文提供了来自羊膜的新型血管生成细胞，称为羊膜衍生的贴壁细胞，以及包含这些细胞的群体和组合物。 本文还提供了获得这样的细胞的方法和使用细胞治疗个体的方法。
-
公开(公告)号：US08367409B2
公开(公告)日：2013-02-05
申请号：US12622352
申请日：2009-11-19
申请人： Stewart Abbot , James W. Edinger , Aleksandar Francki , Aleksandr Kaplunovsky , Vladimir Jankovic , Kristen Labazzo , Eric Law , Neerav D. Padliya , Jennifer Paredes , Jia-Lun Wang
发明人： Stewart Abbot , James W. Edinger , Aleksandar Francki , Aleksandr Kaplunovsky , Vladimir Jankovic , Kristen Labazzo , Eric Law , Neerav D. Padliya , Jennifer Paredes , Jia-Lun Wang
CPC分类号： A61K35/50 , A61K35/12 , C12N5/0605
摘要： Provided herein are novel angiogenic cells from amnion, referred to as amnion derived adherent cells, and populations of, and compositions comprising, such cells. Further provided herein are methods of obtaining such cells and methods of using the cells in the treatment of individuals.
-
公开(公告)号：US09254302B2
公开(公告)日：2016-02-09
申请号：US13081415
申请日：2011-04-06
申请人： Stewart Abbot , James W. Edinger , Aleksandar Francki , Robert J. Hariri , Vladimir Jankovic , Aleksandr Kaplunovsky , Kristen Labazzo , Eric Law , Neerav D. Padliya , Jennifer Paredes , Jia-Lun Wang
发明人： Stewart Abbot , James W. Edinger , Aleksandar Francki , Robert J. Hariri , Vladimir Jankovic , Aleksandr Kaplunovsky , Kristen Labazzo , Eric Law , Neerav D. Padliya , Jennifer Paredes , Jia-Lun Wang
CPC分类号： A61K35/50 , A61K9/0019 , A61K9/0085 , A61K35/28 , A61L27/3633 , A61L27/3683 , A61L27/3808 , A61L27/3834 , A61L27/3886 , A61L27/3895 , C12N5/0605 , A61K2300/00
摘要： Provided herein are methods of treating individuals having diseases or disorders of the circulatory system, using placental cells, e.g., the placental stem cells and placental multipotent cells (PDACs) described herein, and populations of such placental cells. The invention also provides methods of angiogenesis using such cells or populations of cells comprising such cells.
摘要翻译： 本文提供了使用胎盘细胞（例如本文所述的胎盘干细胞和胎盘多潜能细胞（PDAC））以及这些胎盘细胞群来治疗患有循环系统疾病或病症的个体的方法。 本发明还提供了使用这种细胞或包含这种细胞的细胞群的血管生成方法。
-
8.发明申请公开(公告)号：US20150023926A1
公开(公告)日：2015-01-22
申请号：US14232855
申请日：2012-07-13
IPC分类号： A61K35/50
CPC分类号： A61K35/50 , C12N5/0605
摘要： Provided herein are methods of treating individuals having suffered exposure to radiation, e.g., individuals having radiation injury, by administering to the individuals angiogenic cells from amnion, referred to as amnion derived adherent cells, or populations of and compositions comprising, such cells.
摘要翻译： 本文提供了通过对来自羊膜的血管生成细胞（称为羊膜来源的贴壁细胞）或包含这种细胞的组合物的个体进行治疗而暴露于辐射的个体（例如具有放射线损伤的个体）的方法。
-
9.发明申请公开(公告)号：US20140072538A1
公开(公告)日：2014-03-13
申请号：US13940920
申请日：2013-07-12
IPC分类号： A61K35/50
CPC分类号： A61K35/50
摘要： Provided herein are methods of treating individuals having suffered exposure to radiation, e.g., individuals having radiation injury, by administering to the individuals angiogenic cells from amnion, referred to as amnion derived adherent cells, or populations of, and compositions comprising, such cells.
摘要翻译： 本文提供了通过对来自羊膜的称为羊膜来源的贴壁细胞的血管生成细胞或包含这些细胞的组合物以及包含这些细胞的组合物的个体进行治疗而暴露于辐射的个体，例如具有放射线损伤的个体的方法。
-
10.发明申请公开(公告)号：US20100311166A1
公开(公告)日：2010-12-09
申请号：US12161677
申请日：2007-01-18
IPC分类号： C12N5/07
CPC分类号： C12N5/0676 , A61K2035/126 , C12N5/0677 , C12N2501/105 , C12N2501/135 , C12N2501/48 , C12N2501/70 , C12N2509/00 , C12N2533/32 , C12N2533/74
摘要： The invention relates to the discovery that the proliferation and survival of pancreatic progenitor cells can be enhanced by contacting the cells with, (1) a caspase inhibitor sufficient to reduce apoptosis in the pancreatic endocrine cells; and, (2) a growth factor in an amount sufficient to increase the level of activated Akt in the pancreatic endocrine cells.
摘要翻译： 本发明涉及通过使细胞与（1）足以减少胰腺内分泌细胞凋亡的半胱天冬酶抑制剂接触的细胞增强胰腺祖细胞的增殖和存活的发现; 和（2）足以增加胰腺内分泌细胞中活化的Akt水平的生长因子。
-
-
-
-
-
-
-
-
-
搜索结果
11 条记录 (耗时 0.048 秒)
