公开(公告)号：US11685975B2

公开(公告)日：2023-06-27

申请号：US17138492

申请日：2020-12-30

Applicant: Japan Medical Device Technology Co., LTD.

Inventor： Hironori Ueda ,  Masashi Inoue ,  Makoto Sasaki

IPC: C22C23/04 ,  A61L31/02 ,  C22C1/02 ,  C22F1/06 ,  A61L27/04 ,  A61L31/14 ,  A61L27/50

CPC classification number: C22C23/04 ,  A61L27/047 ,  A61L27/50 ,  A61L31/022 ,  A61L31/14 ,  C22C1/02 ,  C22C2202/00 ,  C22F1/06

Abstract: A magnesium alloy containing, in % by mass, 0.95 to 2.00% of Zn, 0.05% or more and less than 0.30% of Zr, 0.05 to 0.20% of Mn, and the balance consisting of Mg and unavoidable impurities, wherein the magnesium alloy has a particle size distribution with an average crystal particle size from 1.0 to 3.0 μm and a standard deviation of 0.7 or smaller.

公开(公告)号：US12109333B2

公开(公告)日：2024-10-08

申请号：US17024262

申请日：2020-09-17

Applicant: Japan Medical Device Technology Co., LTD. ,  FUJI LIGHT METAL CO., LTD.

Inventor： Makoto Sasaki ,  Yuki Koga ,  Yuki Okazawa ,  Hironori Ueda ,  Masashi Inoue ,  Shuzo Yamashita

IPC: A61L31/02 ,  A61F2/82 ,  A61L31/08 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  C08L65/04

CPC classification number: A61L31/022 ,  A61F2/82 ,  A61L31/088 ,  A61L31/10 ,  A61L31/148 ,  A61L31/16 ,  C08L65/04 ,  A61F2210/0004 ,  A61F2210/0076 ,  A61F2250/0068 ,  A61L2300/416 ,  A61L2420/02 ,  A61L2420/08 ,  C08L2201/06 ,  C08L2203/02

Abstract: Provided is a biodegradable stent comprising a magnesium alloy free of a rare earth element and aluminum. The stent comprises: a core structure comprising a magnesium alloy containing 90 wt % or more of magnesium as a main component, and zinc, zirconium, and manganese as accessary components, the magnesium alloy being free of a rare earth element and aluminum; a first corrosion resistant layer formed on the core structure and containing magnesium fluoride as a main component; and a second corrosion resistant layer formed on the first corrosion resistant layer and comprising a parylene. A method for producing such a bioabsorbable stent is also provided.

公开(公告)号：US11248282B2

公开(公告)日：2022-02-15

申请号：US16506298

申请日：2019-07-09

Applicant: FUJI LIGHT METAL CO., LTD. ,  Japan Medical Device Technology Co., LTD.

Inventor： Hironori Ueda ,  Masashi Inoue ,  Makoto Sasaki

IPC: C22C23/04 ,  A61L31/02

Abstract: Magnesium alloy containing, in % by mass, 1.0 to 2.0% of Zn, 0.05 to 0.80% by mass of Zr, 0.05 to 0.40% by mass of Mn, and the balance consisting of Mg and unavoidable impurities. The magnesium alloy may further contain, in % by mass, 0.005% or more and less than 0.20% of Ca.

公开(公告)号：US11160674B2

公开(公告)日：2021-11-02

申请号：US16523645

申请日：2019-07-26

Applicant: Japan Medical Device Technology Co., LTD. ,  FUJI LIGHT METAL CO., LTD.

Inventor： Makoto Sasaki ,  Yuki Koga ,  Yuki Okazawa ,  Hironori Ueda ,  Masashi Inoue

IPC: A61L31/02 ,  A61L31/14 ,  A61L31/06 ,  A61L31/10 ,  A61L31/16 ,  A61F2/90 ,  A61F2/958

Abstract: To provide a stent excellent in deformability, capable of maintaining a radial force for a longer period of time, and having bioabsorbability and a method of producing the same. The bioabsorbable stent has a core structure including a magnesium alloy and a corrosion resistant layer on the core structure, wherein the core structure is formed from a magnesium alloy containing 90 mass % or more of Mg as a main component, Zn, Zr, and Mn as accessory components, and 30 ppm or less of unavoidable impurities selected from the group consisting of Fe, Ni, Co, and Cu, and the alloy excluding aluminum and at least one sort of rare earths selected from the group consisting of Sc, Y, Dy, Sm, Ce, Gd, and La; and the corrosion resistant layer containing magnesium fluoride as a main component with a hydrophilic smooth surface is formed on the core structure with a smooth surface.