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公开(公告)号：US20080084553A1
公开(公告)日：2008-04-10
申请号：US11632471
申请日：2005-07-14
CPC分类号： G01J3/44 , G01J3/28 , G01J3/2823 , G01N21/6486 , G01N21/65 , G01N2201/1293
摘要： In one embodiment, the disclosure relates to a method for detecting and classifying an unknown substance in a sample. The method including the steps of (a) providing a spectrum for each of a predetermined number of reference substances; (b) detecting an area of interest on said unknown substance; (c) targeting said area of interest; (d) determining a spectrum from said area of interest; (e) comparing the determined spectrum with the spectrum of one of the reference substances; and (f) classifying said unknown substance based on the comparison of spectra.
摘要翻译： 在一个实施方案中，本公开涉及用于检测和分类样品中未知物质的方法。 该方法包括以下步骤：（a）为预定数量的参考物质中的每一个提供光谱; （b）检测所述未知物质的感兴趣区域; （c）针对该地区的目标; （d）从所述感兴趣区域确定频谱; （e）将所确定的光谱与参考物质之一的光谱进行比较; 和（f）基于光谱的比较对所述未知物质进行分类。
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2.发明申请System and method for spectral unmixing in a fiber array spectral translator based polymorph screening system 有权基于光纤阵列光谱变换器的多态性筛选系统中光谱解混合的系统和方法公开(公告)号：US20070201022A1
公开(公告)日：2007-08-30
申请号：US11679112
申请日：2007-02-26
IPC分类号： G01J3/00
CPC分类号： G01J3/2803 , G01J3/02 , G01J3/0218 , G01J3/0221 , G01J3/024 , G01J3/0291 , G01J3/0294 , G01J3/04 , G01J3/2823 , G01J3/44 , G01N21/65 , G01N2201/0833 , G01N2201/1293
摘要： The disclosure relates generally to methods and apparatus for using a fiber array spectral translator-based (“FAST”) spectroscopic system for performing spectral unmixing of a mixture containing multiple polymorphs. In an embodiment, a first spectrum of a mixture containing polymorphs of a compound is obtained using a photon detector and a fiber array spectral translator having plural fibers. A set of second spectra is provided where each spectrum of the set of second spectra may be representative of a different polymorph of the compound. The first spectrum and the set of second spectra may be compared, and based on the comparison, the presence of one or more polymorphs in the mixture may be determined.
摘要翻译： 本公开总体上涉及使用用于执行含有多个多晶型物的混合物的光谱解混合的光纤阵列光谱转换器（“FAST”）光谱系统的方法和装置。 在一个实施方案中，使用具有多个纤维的光子检测器和光纤阵列光谱转换器获得含有化合物多晶型物的混合物的第一光谱。 提供了一组第二光谱，其中该组第二光谱的每个光谱可以代表该化合物的不同多晶型物。 可以比较第一光谱和第二光谱集，并且基于比较，可以确定混合物中一个或多个多晶型物的存在。
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3.发明授权System and method for spectral unmixing in a fiber array spectral translator based polymorph screening system 有权基于光纤阵列光谱变换器的多态性筛选系统中光谱解混合的系统和方法公开(公告)号：US07471386B2
公开(公告)日：2008-12-30
申请号：US11679112
申请日：2007-02-26
IPC分类号： G01J3/00
CPC分类号： G01J3/2803 , G01J3/02 , G01J3/0218 , G01J3/0221 , G01J3/024 , G01J3/0291 , G01J3/0294 , G01J3/04 , G01J3/2823 , G01J3/44 , G01N21/65 , G01N2201/0833 , G01N2201/1293
摘要： The disclosure relates generally to methods and apparatus for using a fiber array spectral translator-based (“FAST”) spectroscopic system for performing spectral unmixing of a mixture containing multiple polymorphs. In an embodiment, a first spectrum of a mixture containing polymorphs of a compound is obtained using a photon detector and a fiber array spectral translator having plural fibers. A set of second spectra is provided where each spectrum of the set of second spectra may be representative of a different polymorph of the compound. The first spectrum and the set of second spectra may be compared, and based on the comparison, the presence of one or more polymorphs in the mixture may be determined.
摘要翻译： 本公开总体上涉及使用用于执行含有多个多晶型物的混合物的光谱解混合的光纤阵列光谱转换器（“FAST”）光谱系统的方法和装置。 在一个实施方案中，使用具有多个纤维的光子检测器和光纤阵列光谱转换器获得含有化合物多晶型物的混合物的第一光谱。 提供了一组第二光谱，其中该组第二光谱的每个光谱可以代表该化合物的不同多晶型物。 可以比较第一光谱和第二光谱集，并且基于比较，可以确定混合物中一个或多个多晶型物的存在。
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4.发明授权System and method for image reconstruction in a fiber array spectral translator system 有权光纤阵列光谱转换系统中图像重建的系统和方法公开(公告)号：US07474395B2
公开(公告)日：2009-01-06
申请号：US11674552
申请日：2007-02-13
IPC分类号： G01J3/00
CPC分类号： G01J3/02 , G01J3/0218 , G01J3/0221 , G01J3/28 , G01J3/2803 , G01J3/2823 , G01N21/255 , G01N21/274 , G01N2201/0833
摘要： The disclosure relates generally to methods and apparatus for spectral calibration of a spectroscopic system which includes a fiber array spectral translator. One embodiment relates to a method for obtaining a first image of a known substance using a photon detector and a fiber array spectral translator having plural fibers, wherein the first image comprises at least one pixel; providing a second image of the substance wherein the second image comprises at least one pixel; comparing the first image with the second image; and adjusting at least one pixel of the first image based on the comparison of images to thereby obtain an adjusted image.
摘要翻译： 本公开一般涉及包括光纤阵列光谱转换器的光谱系统的光谱校准的方法和装置。 一个实施例涉及一种使用光子检测器和具有多个光纤的光纤阵列光谱转换器获得已知物质的第一图像的方法，其中第一图像包括至少一个像素; 提供所述物质的第二图像，其中所述第二图像包括至少一个像素; 将第一图像与第二图像进行比较; 以及基于图像的比较来调整第一图像的至少一个像素，从而获得调整后的图像。
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5.发明授权Method and apparatus for compact spectrometer for multipoint sampling of an object 有权用于多物体采样的紧凑型光谱仪的方法和装置公开(公告)号：US07548310B2
公开(公告)日：2009-06-16
申请号：US11366660
申请日：2006-03-03
申请人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
发明人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
IPC分类号： G01J3/44
CPC分类号： G01N21/65 , G01N21/6456 , G01N2021/6421 , G01N2201/0221
摘要： The disclosure relates to methods and apparatus for assessing occurrence of one or more hazardous agents in a sample by performing multipoint spectral analysis of the sample using a portable or hand-held device. Methods of employing Raman spectroscopy and other spectrophotometric methods are disclosed. Devices and systems suitable for performing such multipoint methods are also disclosed.
摘要翻译： 本公开涉及通过使用便携式或手持式装置对样品进行多点光谱分析来评估样品中一种或多种危险剂的发生的方法和装置。 公开了采用拉曼光谱法和其他分光光度法的方法。 还公开了适于执行这种多点方法的设备和系统。
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6.发明授权Method and apparatus for compact spectrometer for fiber array spectral translator 有权用于光纤阵列光谱转换器的紧凑型光谱仪的方法和装置公开(公告)号：US07440096B2
公开(公告)日：2008-10-21
申请号：US11366531
申请日：2006-03-03
申请人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
发明人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
CPC分类号： G01J3/44 , G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0224 , G01J3/0237 , G01J3/0256 , G01J3/0264 , G01J3/0272 , G01J3/0283 , G01J3/0291 , G01J3/10 , G01J3/26 , G01J3/32 , G01J3/36 , G01J3/447 , G01N21/65 , G01N2201/0846
摘要： The disclosure relates to a portable system having a fiber array spectral translator (“FAST”) for obtaining a spatially accurate wavelength-resolved image of a sample having a first and a second spatial dimension that can be used for the detection of hazardous agents by irradiating a sample with light, forming an image of all or part of the sample using Raman shifted light from the sample, and analyzing the Raman shifted light for patterns characteristic of one or more hazardous agents.
摘要翻译： 本公开涉及一种具有光纤阵列光谱转换器（“FAST”）的便携式系统，用于获得具有第一和第二空间尺寸的样品的空间准确的波长分辨图像，所述第一和第二空间尺寸可用于通过照射来检测危险物质 具有光的样品，使用来自样品的拉曼移动光形成全部或部分样品的图像，并且分析拉曼偏移光以获得一种或多种危险剂的特征。
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7.发明授权System and method for super resolution of a sample in a fiber array spectral translator system 有权用于光纤阵列光谱转换器系统中样品超分辨率的系统和方法公开(公告)号：US07764371B2
公开(公告)日：2010-07-27
申请号：US11675155
申请日：2007-02-15
IPC分类号： G01J3/00
CPC分类号： G01T1/20
摘要： The disclosure relates generally to methods and apparatus for obtaining a super resolution image of a sample using a fiber array spectral translator system. In one embodiment includes collecting photons from a sample at a first end of a fiber array spectral translator; delivering the photons from a second end of the fiber array spectral translator into a multiple detector rows of a photon detector; interpolating between the multiple detector rows to thereby form interpolated rows; and arranging an output of the multiple detector rows and the interpolated rows so as to obtain a super resolution image of the sample.
摘要翻译： 本公开一般涉及使用光纤阵列频谱转换器系统获得样本的超分辨率图像的方法和装置。 在一个实施例中，包括在光纤阵列光谱转换器的第一端收集来自样品的光子; 将光子从光纤阵列频谱转换器的第二端传送到光子检测器的多个检测器行中; 在多个检测器行之间内插，从而形成内插行; 并且布置多个检测器行和内插行的输出，以便获得样本的超分辨率图像。
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8.发明授权Method and apparatus for compact spectrometer for detecting hazardous agents 有权用于检测危险物质的紧凑型光谱仪的方法和装置公开(公告)号：US07738095B2
公开(公告)日：2010-06-15
申请号：US11366532
申请日：2006-03-03
申请人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
发明人： Charles W. Gardner, Jr. , John S. Maier , Matthew P. Nelson , Robert C. Schweitzer , Patrick J. Treado , G. Steven Vanni , Julianne Wolfe , Joseph E. Demuth , Jason H. Neiss , Chenhui Wang
CPC分类号： G01J3/44 , G01J3/02 , G01J3/0205 , G01J3/0218 , G01J3/0256 , G01J3/0264 , G01J3/0272 , G01J3/0283 , G01J3/0291 , G01J3/10 , G01J3/26 , G01J3/28 , G01J3/2823 , G01N21/6456 , G01N21/65 , G01N2021/6423 , G01N2201/0221
摘要： The disclosure relates to a portable system for obtaining a spatially accurate wavelength-resolved image of a sample having a first and a second spatial dimension that can be used for the detection of hazardous agents by irradiating a sample with light, forming an image of all or part of the sample using Raman shifted light from the sample, and analyzing the Raman shifted light for patterns characteristic of one or more hazardous agents.
摘要翻译： 本公开涉及一种便携式系统，用于获得具有第一和第二空间尺寸的样本的空间上准确的波长分辨图像，该图像可以用于通过用光照射样品来检测危险剂，形成全部或全部图像 使用拉曼的样品的一部分移动来自样品的光，并且分析拉曼偏移光以获得一种或多种危险剂的特征。
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9.发明申请SYSTEM AND METHOD FOR IMAGE RECONSTRUCTION IN A FIBER ARRAY SPECTRAL TRANSLATOR SYSTEM 有权一种光纤阵列传输系统中图像重构的系统与方法公开(公告)号：US20070188747A1
公开(公告)日：2007-08-16
申请号：US11674552
申请日：2007-02-13
CPC分类号： G01J3/02 , G01J3/0218 , G01J3/0221 , G01J3/28 , G01J3/2803 , G01J3/2823 , G01N21/255 , G01N21/274 , G01N2201/0833
摘要： The disclosure relates generally to methods and apparatus for spectral calibration of a spectroscopic system which includes a fiber array spectral translator. One embodiment relates to a method for obtaining a first image of a known substance using a photon detector and a fiber array spectral translator having plural fibers, wherein the first image comprises at least one pixel; providing a second image of the substance wherein the second image comprises at least one pixel; comparing the first image with the second image; and adjusting at least one pixel of the first image based on the comparison of images to thereby obtain an adjusted image.
摘要翻译： 本公开一般涉及包括光纤阵列光谱转换器的光谱系统的光谱校准的方法和装置。 一个实施例涉及一种使用光子检测器和具有多个光纤的光纤阵列光谱转换器获得已知物质的第一图像的方法，其中第一图像包括至少一个像素; 提供所述物质的第二图像，其中所述第二图像包括至少一个像素; 将第一图像与第二图像进行比较; 以及基于图像的比较来调整第一图像的至少一个像素，从而获得调整后的图像。
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10.发明申请Motion invariant generalized hyperspectral targeting and identification methodology and apparatus therefor 审中-公开运动不变式广义高光谱目标识别方法及其设备公开(公告)号：US20100322471A1
公开(公告)日：2010-12-23
申请号：US11544727
申请日：2006-10-10
申请人： Patrick J. Treado , Jason H. Neiss
发明人： Patrick J. Treado , Jason H. Neiss
IPC分类号： G06T7/00
CPC分类号： G01N21/6456 , G01J3/2823 , G01N21/359 , G01N21/65 , G01N33/0004 , G01N2021/1793 , G01N2021/3531 , G01N2021/6423
摘要： The present disclosure relates to a method and system for enhancing the ability of nuclear, chemical, and biological (“NBC”) sensors, specifically mobile sensors, to detect, analyze, and identify NBC agents on a surface, in an aerosol, in a vapor cloud, or other similar environment. Embodiments include the use of a two-stage approach including targeting and identification of a contaminant. Spectral imaging sensors may be used for both wide-field detection (e.g., for scene classification) and narrow-field identification.
摘要翻译： 本公开内容涉及一种用于增强核，化学和生物（“NBC”）传感器，特别是移动传感器在表面上，气溶胶中检测，分析和鉴定NBC试剂的能力的方法和系统， 蒸汽云或其他类似环境。 实施方案包括使用包括靶向和鉴定污染物的两阶段方法。 光谱成像传感器可用于宽场检测（例如，用于场景分类）和窄场识别。
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