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公开(公告)号：US08100528B2
公开(公告)日：2012-01-24
申请号：US12334619
申请日：2008-12-15
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , A61M25/0045 , C08F130/08 , C08F230/00 , C08F293/005 , C08F2438/03 , C08J7/04 , C08J2343/04 , C08J2383/00 , Y10T428/31536 , Y10T428/31663
摘要： This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of interactive segmented block copolymers to the surface of the substrate by means of interactive functionalities of the segmented block copolymer reacting with complementary surface functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
摘要翻译： 本发明涉及一种装置的表面处理。 表面处理包括通过与沿着聚合物基底的单体单元的互补表面官能团反应的分段嵌段共聚物的相互作用官能团将相互作用的嵌段共聚物连接到基材的表面。 本发明还涉及一种表面改性医疗装置，其实例包括隐形眼镜，眼内透镜，血管支架，晶状体眼内透镜，无晶状体眼内透镜，角膜植入物，导管，植入物等，其包括由 这样一种方法。
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公开(公告)号：US20090171027A1
公开(公告)日：2009-07-02
申请号：US12334615
申请日：2008-12-15
IPC分类号： C08F299/00
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , A61M25/0045 , C08F130/08 , C08F230/00 , C08F293/005 , C08F2438/03 , C08J7/04 , C08J2343/04 , C08J2383/00 , Y10T428/31536 , Y10T428/31663
摘要： This invention is directed toward interactive segmented block copolymers useful to treat the surface of a substrate by means of interactive functionalities of the interactive segmented block copolymer material binding with complementary surface functionalities of the polymer substrate.
摘要翻译： 本发明涉及用于通过与聚合物基质的互补表面官能团结合的相互作用的分段嵌段共聚物材料的相互作用功能来处理基材表面的相互作用的嵌段共聚物。
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公开(公告)号：US07942929B2
公开(公告)日：2011-05-17
申请号：US12334618
申请日：2008-12-15
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , A61M25/0045 , C08F130/08 , C08F230/00 , C08F293/005 , C08F2438/03 , C08J7/04 , C08J2343/04 , C08J2383/00 , Y10T428/31536 , Y10T428/31663
摘要： This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of reactive segmented block copolymers to the surface of the substrate by means of reactive functionalities of the terminal functionalized surfactant material reacting with complementary surface reactive functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
摘要翻译： 本发明涉及一种装置的表面处理。 表面处理包括通过末端官能化表面活性剂材料与沿聚合物基质的单体单元的互补表面反应性官能团反应的反应性官能团将反应性嵌段共聚物附着到基材表面。 本发明还涉及一种表面改性医疗装置，其实例包括隐形眼镜，眼内透镜，血管支架，晶状体眼内透镜，无晶状体眼内透镜，角膜植入物，导管，植入物等，包括由 这样一种方法。
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4.发明申请公开(公告)号：US20090171459A1
公开(公告)日：2009-07-02
申请号：US12334618
申请日：2008-12-15
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , A61M25/0045 , C08F130/08 , C08F230/00 , C08F293/005 , C08F2438/03 , C08J7/04 , C08J2343/04 , C08J2383/00 , Y10T428/31536 , Y10T428/31663
摘要： This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of reactive segmented block copolymers to the surface of the substrate by means of reactive functionalities of the terminal functionalized surfactant material reacting with complementary surface reactive functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
摘要翻译： 本发明涉及一种装置的表面处理。 表面处理包括通过末端官能化表面活性剂材料与沿聚合物基质的单体单元的互补表面反应性官能团反应的反应性官能团将反应性嵌段共聚物附着到基材表面。 本发明还涉及一种表面改性医疗装置，其实例包括隐形眼镜，眼内透镜，血管支架，晶状体眼内透镜，无晶状体眼内透镜，角膜植入物，导管，植入物等，包括由 这样一种方法。
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公开(公告)号：US20090171049A1
公开(公告)日：2009-07-02
申请号：US12333345
申请日：2008-12-12
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , A61M25/0045 , C08F130/08 , C08F230/00 , C08F293/005 , C08F2438/03 , C08J7/04 , C08J2343/04 , C08J2383/00 , Y10T428/31536 , Y10T428/31663
摘要： This invention is directed toward reactive segmented block copolymers useful to treat the surface of a substrate by means of reactive functionalities of the reactive segmented block copolymer material reacting with complementary surface reactive functionalities of the polymer substrate.
摘要翻译： 本发明涉及用于通过与聚合物基质的互补表面反应性官能团反应的反应性嵌段共聚物材料的反应性官能团来处理基材表面的反应性分段嵌段共聚物。
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公开(公告)号：US08083348B2
公开(公告)日：2011-12-27
申请号：US12456420
申请日：2009-06-16
CPC分类号： G02B1/043 , C08F20/56 , C08F26/08 , C08F118/02 , C08F226/02 , C08L81/00 , C08L83/10
摘要： Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising an ethylenically unsaturated-containing non-amphiphilic macromonomer comprising hydrophilic units or hydrophobic units derived from a living radical polymerization of one or more ethylenically unsaturated hydrophilic monomers or one or more ethylenically unsaturated hydrophobic monomers are disclosed.
摘要翻译： 生物医学装置，例如由含有烯键式不饱和的非两亲性大分子单体的混合物的聚合产物形成的隐形眼镜，其包含亲水单元或衍生自一种或多种烯属不饱和亲水单体的活性自由基聚合的疏水单元或一种或多种烯属不饱和单体 公开疏水单体。
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公开(公告)号：US20090168012A1
公开(公告)日：2009-07-02
申请号：US12334619
申请日：2008-12-15
IPC分类号： G02C7/04 , C08F130/08 , A61F2/24 , A61F2/16 , A61F2/06 , A61F2/14 , A61F2/12 , A61F2/02 , A61M25/00
CPC分类号： G02B1/043 , A61L27/34 , A61L31/10 , A61M25/0045 , C08F130/08 , C08F230/00 , C08F293/005 , C08F2438/03 , C08J7/04 , C08J2343/04 , C08J2383/00 , Y10T428/31536 , Y10T428/31663
摘要： This invention is directed toward surface treatment of a device. The surface treatment comprises the attachment of interactive segmented block copolymers to the surface of the substrate by means of interactive functionalities of the segmented block copolymer reacting with complementary surface functionalities in monomeric units along the polymer substrate. The present invention is also directed to a surface modified medical device, examples of which include contact lenses, intraocular lenses, vascular stents, phakic intraocular lenses, aphakic intraocular lenses, corneal implants, catheters, implants, and the like, comprising a surface made by such a method.
摘要翻译： 本发明涉及一种装置的表面处理。 表面处理包括通过与沿着聚合物基底的单体单元的互补表面官能团反应的分段嵌段共聚物的相互作用官能团将相互作用的嵌段共聚物连接到基材的表面。 本发明还涉及一种表面改性医疗装置，其实例包括隐形眼镜，眼内透镜，血管支架，晶状体眼内透镜，无晶状体眼内透镜，角膜植入物，导管，植入物等，包括由 这样一种方法。
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公开(公告)号：US20100317816A1
公开(公告)日：2010-12-16
申请号：US12456420
申请日：2009-06-16
IPC分类号： C08F26/08 , C08F226/02 , C08F20/56 , C08F118/02 , C08F112/08 , G02C7/04
CPC分类号： G02B1/043 , C08F20/56 , C08F26/08 , C08F118/02 , C08F226/02 , C08L81/00 , C08L83/10
摘要： Biomedical devices such as contact lenses formed from a comprising a polymerization product of a mixture comprising an ethylenically unsaturated-containing non-amphiphilic macromonomer comprising hydrophilic units or hydrophobic units derived from a living radical polymerization of one or more ethylenically unsaturated hydrophilic monomers or one or more ethylenically unsaturated hydrophobic monomers are disclosed.
摘要翻译： 生物医学装置如隐形眼镜由包含含有烯属不饱和的非两亲性大分子单体的混合物的聚合产物形成，所述混合物包含亲水单元或衍生自一种或多种烯属不饱和亲水单体的活性自由基聚合的疏水单元或一种或多种 公开了烯属不饱和疏水单体。
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公开(公告)号：US20100315588A1
公开(公告)日：2010-12-16
申请号：US12456422
申请日：2009-06-16
申请人： Ivan M. Nunez , Jeffrey G. Linhardt , Joseph A. McGee , Jennifer Hunt , Michele Alton , Devon A. Shipp , Jay F. Kunzler , Daniel M. Ammon, JR.
发明人： Ivan M. Nunez , Jeffrey G. Linhardt , Joseph A. McGee , Jennifer Hunt , Michele Alton , Devon A. Shipp , Jay F. Kunzler , Daniel M. Ammon, JR.
摘要： Biomedical devices such as contact lenses formed from a polymerization product of a mixture comprising (a) a hydrophilic polymer comprising one or more hydrophilic units and one or more thio carbonyl thio fragments of a reversible addition fragmentation chain transfer (“RAFT”) agent; and (b) one or more biomedical device-forming monomers are disclosed.
摘要翻译： 生物医学装置，例如由混合物的聚合产物形成的隐形眼镜，所述混合物包含（a）包含一个或多个亲水单元的亲水性聚合物和一个或多个可逆加成断裂链转移（“RAFT”）试剂的一个或多个硫羰基硫代片段; 和（b）公开了一种或多种生物医学装置形成单体。
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公开(公告)号：US20100069522A1
公开(公告)日：2010-03-18
申请号：US12404672
申请日：2009-03-16
IPC分类号： B29D11/00 , C08F271/02 , C08J3/28
CPC分类号： G02B1/043 , C08G77/442 , C08L83/10
摘要： This invention describes the use of amphiphilic multiblock copolymers comprising a hydrophobic segment and a hydrophilic the amphiphilic multiblock copolymer has at least one thio carbonyl thio group capable of participating in a free radical reaction as comonomers in forming ophthalmic devices such as contact lenses, intraocular lenses, corneal implants, etc.
摘要翻译： 本发明描述了包含疏水链段和亲水性两亲性多嵌段共聚物的两亲性多嵌段共聚物的用途，其具有至少一个能够参与自由基反应的硫羰基硫基，作为共聚单体在形成眼科装置如隐形眼镜，人工晶状体， 角膜植入物等
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