公开(公告)号：US20060052372A1

公开(公告)日：2006-03-09

申请号：US11265030

申请日：2005-11-02

申请人： Jesse May ,  Thomas Dean ,  Najam Sharif ,  Hwang-Hsing Chen

发明人： Jesse May ,  Thomas Dean ,  Najam Sharif ,  Hwang-Hsing Chen

IPC分类号： A61K31/5415 ,  A61K31/18 ,  C07C279/02 ,  C07D417/02

CPC分类号： C07D295/088 ,  C07D209/08 ,  C07D217/04 ,  C07D235/26 ,  C07D295/13 ,  C07D401/12 ,  C07D513/04

摘要： Compounds with 5HT7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, depression, and other psychiatric disorders, such as, schizophrenia, anxiety, obsessive compulsive disorder, circadian rhythm disorders, and centrally and peripherally mediated hypertension. Compositions and methods for their use are also disclosed.

摘要翻译： 公开了可用于降低IOP，改善视神经头和视网膜的血流量，提供神经保护和治疗视网膜疾病的具有5HT 7受体亲和力（其中一些是新颖的）的化合物。 化合物还可用于治疗睡眠障碍，抑郁症和其他精神病学障碍，例如精神分裂症，焦虑症，强迫症，昼夜节律紊乱以及中枢和外周介导的高血压。 还公开了其使用的组合物和方法。

公开(公告)号：US20050187214A1

公开(公告)日：2005-08-25

申请号：US11100918

申请日：2005-04-07

申请人： Jesse May ,  Thomas Dean ,  Najam Sharif ,  Hwang-Hsing Chen

发明人： Jesse May ,  Thomas Dean ,  Najam Sharif ,  Hwang-Hsing Chen

IPC分类号： C07D209/08 ,  C07D295/088 ,  C07D295/13 ,  C07D513/04 ,  C07D279/16 ,  A61K31/5415

CPC分类号： C07D295/088 ,  C07D209/08 ,  C07D217/04 ,  C07D235/26 ,  C07D295/13 ,  C07D401/12 ,  C07D513/04

摘要： Compounds with 5HT7 receptor affinity (some of which are novel) useful for lowering IOP, improving blood flow to the optic nerve head and the retina, providing neuroprotection, and treating retinal diseases are disclosed. The Compounds are also useful for treating sleep disorders, depression, and other psychiatric disorders, such as, schizophrenia, anxiety, obsessive compulsive disorder, circadian rhythm disorders, and centrally and peripherally mediated hypertension. Compositions and methods for their use are also disclosed.

摘要翻译： 公开了可用于降低IOP，改善视神经头和视网膜的血流量，提供神经保护和治疗视网膜疾病的具有5HT 7受体亲和力（其中一些是新颖的）的化合物。 化合物还可用于治疗睡眠障碍，抑郁症和其他精神病学障碍，例如精神分裂症，焦虑症，强迫症，昼夜节律紊乱以及中枢和外周介导的高血压。 还公开了其使用的组合物和方法。

公开(公告)号：US20060102847A1

公开(公告)日：2006-05-18

申请号：US10991694

申请日：2004-11-18

申请人： Paul Shelley ,  Peter VanVoast ,  Thomas Dean ,  Bruce Davis

发明人： Paul Shelley ,  Peter VanVoast ,  Thomas Dean ,  Bruce Davis

IPC分类号： G01J1/42

CPC分类号： G01J3/443

摘要： A method and system are provided for real-time contaminant detection and plasma treatment verification during plasma treatment of bonding surfaces. Optical emission spectroscopy (OES) is utilized to determine contamination of a bonding surface prior to the bonding process. OES is further utilized to monitor bonding sites on the bonding surface to verify effectiveness of the plasma treatment.

摘要翻译： 提供了一种方法和系统，用于等离子体处理接合表面时的实时污染物检测和等离子体处理验证。 使用光发射光谱（OES）来确定接合过程之前粘合表面的污染。 OES进一步用于监测接合表面上的结合部位，以验证等离子体处理的有效性。

公开(公告)号：US06575864B1

公开(公告)日：2003-06-10

申请号：US09936281

申请日：2001-09-10

申请人： Thomas Dean

发明人： Thomas Dean

IPC分类号： F16H1904

CPC分类号： E05F15/603 ,  E05F15/638 ,  E05Y2201/214 ,  E05Y2201/218 ,  E05Y2201/22 ,  E05Y2201/244 ,  E05Y2201/246 ,  E05Y2201/462 ,  E05Y2900/531 ,  Y10T74/18088

摘要： A drive mechanism (14) for enabling driving and manual movement of a sliding side door (12). The assembly (14) has a track assembly (16) mounted to a vehicle body (10) at a predetermined height and a drive mechanism (18) mounted to the sliding side door (12) so as to be proximate to a door latching mechanism (19). The drive mechanism (18) has an input drive motor (22) driving an output gear assembly (24) engaging the track assembly (16) and a transmission gear assembly (23) with a sliding gear (50) which selectively couples the input drive motor (22) and an input gear assembly (23) to the output gear assembly (24) between an engaged position for driving movement or disengaged position for manual movement of the sliding side door (12). In this way, the slide side door (12) may be moved manually between open and closed positions without having to overcome the effort required of rotating the drive motor (22).

摘要翻译： 一种用于使滑动侧门（12）的驱动和手动移动的驱动机构（14）。 组件（14）具有以预定高度安装到车体（10）的轨道组件（16）和安装到滑动侧门（12）上的驱动机构（18），以便靠近门闩锁机构 （19）。 驱动机构（18）具有驱动与轨道组件（16）接合的输出齿轮组件（24）的输入驱动马达（22）和具有滑动齿轮（50）的传动齿轮组件（23），该滑动齿轮选择性地将输入驱动 电动机（22）和输入齿轮组件（23）之间，用于驱动运动的接合位置或用于滑动侧门（12）的手动运动的脱离位置。 以这种方式，滑动侧门（12）可以在打开和关闭位置之间手动移动，而不必克服旋转驱动马达（22）所需的努力。

公开(公告)号：US06375207B1

公开(公告)日：2002-04-23

申请号：US09510544

申请日：2000-02-22

申请人： Thomas Dean ,  Robert R. MCaughey ,  Brad Armstrong ,  Lassi M. Ojanen ,  Robert D. Worley ,  John Kleino ,  Paul Pirone

发明人： Thomas Dean ,  Robert R. MCaughey ,  Brad Armstrong ,  Lassi M. Ojanen ,  Robert D. Worley ,  John Kleino ,  Paul Pirone

IPC分类号： B62D2522

CPC分类号： B60R3/02

摘要： A retractable running board assembly has a step, at least two support arms, at least two mounting brackets, at least two pairs of parallel links and a drive. The step has an elongated stepping surface extending generally parallel to a longitudinal axis of a vehicle on which the running board assembly is mounted. The support arms are mounted to the step. The mounting brackets are connected to an underside of the vehicle. The parallel links are pivotally connected between each of the support arms and the mounting brackets. The drive effects movement of the step between an extended outboard position and a retracted inboard position.

摘要翻译： 可伸缩行进板组件具有台阶，至少两个支撑臂，至少两个安装支架，至少两对平行链节和驱动器。 台阶具有大致平行于其上安装有行驶板组件的车辆的纵向轴线延伸的细长的步进表面。 支撑臂安装在台阶上。 安装支架连接到车辆的下侧。 平行连杆枢转地连接在每个支撑臂和安装支架之间。 驱动效应在延伸的外侧位置和缩回的内侧位置之间的台阶移动。

公开(公告)号：US06321488B1

公开(公告)日：2001-11-27

申请号：US09513694

申请日：2000-02-25

申请人： Maciek Bigoszewski ,  Thomas Dean ,  Thomas P. Frommer ,  Tad Podwysocki ,  Venkateswar Sagi ,  Michael Schupp ,  Brian Wood

发明人： Maciek Bigoszewski ,  Thomas Dean ,  Thomas P. Frommer ,  Tad Podwysocki ,  Venkateswar Sagi ,  Michael Schupp ,  Brian Wood

IPC分类号： E05F1100

CPC分类号： E05F15/638 ,  E05Y2201/216 ,  E05Y2201/246 ,  E05Y2201/434 ,  E05Y2201/462 ,  E05Y2600/41 ,  E05Y2600/46 ,  E05Y2900/531

摘要： A power sliding door assembly for a motor vehicle comprising a door structure constructed and arranged to be mounted on a motor vehicle for movement between closed and opened positions and a drive assembly mounted on the door structure. The drive assembly includes a rotatable gear engageable with a gear track provided on the vehicle. The rotatable gear is drivable in a one direction to effect movement of the door towards the opened position and drivable in an opposite direction to effect movement of the door structure towards the closed position. A drive shaft is coupled with the drive assembly and is constructed and arranged to rotatably drive the rotatable gear. A reversible motor is mounted on said door structure and is energizable to drive the drive shaft in a first direction to enable the drive shaft to drive the rotatable gear in the one direction, and energizable to drive the drive shaft in a second direction opposite the first direction to enable the drive shaft to drive the rotatable gear in the opposite direction. A clutch assembly is provided that is constructed and arranged to selectively couple the reversible motor with the drive shaft, so that the reversible motor is coupled to the drive shaft when energized to rotate the drive shaft in either of the first and second directions, and so that the reversible motor is de-coupled from the drive shaft to prevent back-driving of the motor when the door structure is manually moved between the opened and closed positions.

摘要翻译： 一种用于机动车辆的动力滑动门组件，包括门结构，其构造和布置成安装在机动车辆上以在关闭位置和打开位置之间运动，以及安装在门结构上的驱动组件。 驱动组件包括可与设置在车辆上的齿轮啮合的可旋转齿轮。 可旋转齿轮可以沿一个方向驱动，以实现门向打开位置的移动，并可沿相反方向驱动，以实现门结构朝向关闭位置的移动。 驱动轴与驱动组件联接并且构造和布置成可旋转地驱动可旋转齿轮。 可逆电动机安装在所述门结构上并且可激励以沿第一方向驱动所述驱动轴，以使得所述驱动轴能够沿所述一个方向驱动所述可旋转齿轮，并且可激励以沿与第一方向相反的第二方向驱动所述驱动轴 方向使得驱动轴能够沿相反方向驱动可旋转齿轮。 提供了一种离合器组件，其被构造和布置成选择性地将可逆电动机与驱动轴联接，使得当通电时可逆电动机联接到驱动轴，以在第一和第二方向中的任一方向上旋转驱动轴，因此 当门结构在打开和关闭位置之间手动移动时，可逆电动机从驱动轴脱耦合以防止马达的反向驱动。

公开(公告)号：US07144068B2

公开(公告)日：2006-12-05

申请号：US10994046

申请日：2004-11-19

申请人： Peter Lance Oxley ,  Peter Lejbjuk ,  Thomas Dean

发明人： Peter Lance Oxley ,  Peter Lejbjuk ,  Thomas Dean

IPC分类号： B60J5/06

CPC分类号： B60J5/06 ,  E05F15/646 ,  E05Y2201/216 ,  E05Y2201/218 ,  E05Y2201/246 ,  E05Y2201/462 ,  E05Y2900/531

摘要： A drive mechanism assembly for enabling driving and manual movement of a sliding side door. The assembly has a track assembly mounted to a vehicle body at a predetermined height and a drive mechanism mounted to the sliding side door so as to be proximate to a door latching mechanism. The drive mechanism has an input drive motor driving an output gear assembly engaging the track assembly and a transmission gear assembly with a sliding gear which selectively couples the input drive motor and an input gear assembly to the output gear assembly between an engaged position for driving movement or disengaged position for manual movement of the sliding side door. In this way, the slide side door may be moved manually between open and closed positions without having to overcome the effort required of rotating the drive motor.

摘要翻译： 一种驱动机构组件，用于使滑动侧门的驱动和手动运动。 组件具有以预定高度安装到车体的轨道组件和安装到滑动侧门以便靠近门闩机构的驱动机构。 驱动机构具有输入驱动马达驱动与轨道组件接合的输出齿轮组件和具有滑动齿轮的传动齿轮组件，该滑动齿轮选择性地将输入驱动马达和输入齿轮组件耦合到输出齿轮组件，用于驱动运动的啮合位置 或滑动侧门的手动移动的脱离位置。 以这种方式，滑动侧门可以在打开和关闭位置之间手动地移动，而不必克服旋转驱动马达所需的努力。

公开(公告)号：US20050256129A1

公开(公告)日：2005-11-17

申请号：US11187474

申请日：2005-07-22

申请人： Robert Collier ,  Michael Kapin ,  Mark Hellberg ,  Thomas Dean

发明人： Robert Collier ,  Michael Kapin ,  Mark Hellberg ,  Thomas Dean

IPC分类号： A61K31/496 ,  A61K31/506 ,  A61K31/519

CPC分类号： A61K31/519 ,  A61K31/496 ,  A61K31/506 ,  Y10S514/912

摘要： Compositions and methods for treating disorders of the outer retina with compounds with 5-HT1A agonist activity are disclosed.

摘要翻译： 公开了用具有5-HT 1A激动剂活性的化合物治疗外部视网膜疾病的组合物和方法。

公开(公告)号：US20050110300A1

公开(公告)日：2005-05-26

申请号：US10994046

申请日：2004-11-19

申请人： Peter Lance Oxley ,  Peter Lejbjuk ,  Thomas Dean

发明人： Peter Lance Oxley ,  Peter Lejbjuk ,  Thomas Dean

IPC分类号： B60J5/06 ,  E05F15/14

CPC分类号： B60J5/06 ,  E05F15/646 ,  E05Y2201/216 ,  E05Y2201/218 ,  E05Y2201/246 ,  E05Y2201/462 ,  E05Y2900/531

摘要： A drive mechanism assembly for enabling driving and manual movement of a sliding side door. The assembly has a track assembly mounted to a vehicle body at a predetermined height and a drive mechanism mounted to the sliding side door so as to be proximate to a door latching mechanism. The drive mechanism has an input drive motor driving an output gear assembly engaging the track assembly and a transmission gear assembly with a sliding gear which selectively couples the input drive motor and an input gear assembly to the output gear assembly between an engaged position for driving movement or disengaged position for manual movement of the sliding side door. In this way, the slide side door may be moved manually between open and closed positions without having to overcome the effort required of rotating the drive motor.

摘要翻译： 一种驱动机构组件，用于使滑动侧门的驱动和手动运动。 组件具有以预定高度安装到车体的轨道组件和安装到滑动侧门以便靠近门闩机构的驱动机构。 驱动机构具有输入驱动马达驱动与轨道组件接合的输出齿轮组件和具有滑动齿轮的传动齿轮组件，该滑动齿轮选择性地将输入驱动马达和输入齿轮组件耦合到输出齿轮组件，用于驱动运动的啮合位置 或滑动侧门的手动移动的脱离位置。 以这种方式，滑动侧门可以在打开和关闭位置之间手动地移动，而不必克服旋转驱动马达所需的努力。

公开(公告)号：US4218015A

公开(公告)日：1980-08-19

申请号：US930893

申请日：1978-08-04

申请人： Thomas Dean

发明人： Thomas Dean

IPC分类号： A01B29/06 ,  A01M7/00 ,  B05B9/00

CPC分类号： A01B29/06 ,  A01M7/0085

摘要： A garden roller capable of storing and dispensing a large volume of liquid without immobilizing the roller, includes a hollow drum, preferably made of plastic and having a handle pivotally connected thereto for rolling the drum. A flexible conduit passes outwardly from the interior of the drum through a flow aperture in an end wall of the drum and a seal is provided to prevent escape of liquid through the aperture. Liquid can be dispensed through the conduit via a pump connected to the conduit outside the drum or by pressurizing the interior of the drum. The flexible conduit is weighted at its open end such that it remains adjacent the bottom of the drum enabling the entire contents therein to be dispensed.

摘要翻译： 能够在不固定辊的情况下储存和分配大量液体的花园滚子包括优选由塑料制成的中空滚筒，并且具有可枢转地连接到其上的用于滚动滚筒的手柄。 柔性导管从鼓的内部通过滚筒的端壁中的流动孔向外通过，并且设置密封件以防止液体通过孔径逸出。 液体可以通过连接到滚筒外部的导管的泵或通过对滚筒的内部加压而通过导管分配。 柔性导管在其开口端被加重，使得其保持邻近滚筒的底部，使得其中的全部内容物能够被分配。