OBTAINING DATA FOR AUTOMATIC GLAUCOMA SCREENING, AND SCREENING AND DIAGNOSTIC TECHNIQUES AND SYSTEMS USING THE DATA
    1.
    发明申请
    OBTAINING DATA FOR AUTOMATIC GLAUCOMA SCREENING, AND SCREENING AND DIAGNOSTIC TECHNIQUES AND SYSTEMS USING THE DATA 有权
    获取用于自动GLAUCOMA筛选的数据,以及使用数据的筛选和诊断技术和系统

    公开(公告)号:US20120230564A1

    公开(公告)日:2012-09-13

    申请号:US13510290

    申请日:2010-11-16

    IPC分类号: G06K9/46

    摘要: A non-stereo fundus image is used to obtain a plurality of glaucoma indicators. Additionally, genome data for the subject is used to obtain genetic marker data relating to one or more genes and/or SNPs associated with glaucoma. The glaucoma indicators indicators and genetic marker data are input into an adaptive model operative to generate an output indicative of a risk of glaucoma in the subject. In combination, the genetic indicators and genome data are more informative about the risk of glaucoma than either of the two in isolation. The adaptive model may be a two-stage model, having a first stage in which individual genetic indicators are combined with respective portions of the genome data by first adaptive model modules to form respective first outputs, and a second stage in which the first outputs are combined by a second adaptive mode. Texture analysis is performed on the fundus images to classify them based on their quality, and only images which are determined to meet a quality criterion are subjected to an analysis to determine if they exhibit glaucoma indicators. Also, the images are put into a standard format. The system may include estimating the position of the optic cup by combining results from multiple optic cup segmentation techniques. The system may include estimating the position of the optic disc by applying edge detection to the funds image, excluding edge points that are unlikely to be optic disc boundary points, and estimating the position of an optic disc by fitting an ellipse to the remaining edge points.

    摘要翻译: 使用非立体眼底图像来获得多个青光眼指示符。 此外,用于受试者的基因组数据用于获得与与青光眼相关的一个或多个基因和/或SNP相关的遗传标记数据。 青光眼指标指标和遗传标记数据被输入到适应模型中,该模型用于产生指示受试者青光眼风险的输出。 综合来看,遗传指标和基因组数据对于青光眼的风险比孤立的两者之一更有信息。 自适应模型可以是两阶段模型,其具有第一阶段,其中通过第一自适应模型模块将个体遗传指标与基因组数据的相应部分组合以形成相应的第一输出,第二阶段中,第一输出是 通过第二自适应模式组合。 对眼底图像进行纹理分析,根据其质量对其进行分类,仅对满足质量标准的图像进行分析,以确定其是否呈现青光眼指标。 此外,图像被放入标准格式。 该系统可以包括通过组合来自多个光学杯分割技术的结果来估计光学杯的位置。 该系统可以包括通过对资金图像应用边缘检测来估计视盘的位置,不包括不太可能是视盘边界点的边缘点,以及通过将椭圆拟合到剩余边缘点来估计视盘的位置 。

    Obtaining data for automatic glaucoma screening, and screening and diagnostic techniques and systems using the data
    2.
    发明授权
    Obtaining data for automatic glaucoma screening, and screening and diagnostic techniques and systems using the data 有权
    获取自动青光眼筛查数据,以及使用数据的筛选和诊断技术和系统

    公开(公告)号:US09107617B2

    公开(公告)日:2015-08-18

    申请号:US13510290

    申请日:2010-11-16

    IPC分类号: A61B3/12 A61B5/02 A61B5/00

    摘要: A non-stereo fundus image is used to obtain a plurality of glaucoma indicators. Additionally, genome data for the subject is used to obtain genetic marker data relating to one or more genes and/or SNPs associated with glaucoma. The glaucoma indicators and genetic marker data are input into an adaptive model operative to generate an output indicative of a risk of glaucoma in the subject. In combination, the genetic indicators and genome data are more informative about the risk of glaucoma than either of the two in isolation. The adaptive model may be a two-stage model, having a first stage in which individual genetic indicators are combined with respective portions of the genome data by first adaptive model modules to form respective first outputs, and a second stage in which the first outputs are combined by a second adaptive mode. Texture analysis is performed on the fundus images to classify them based on their quality, and only images which are determined to meet a quality criterion are subjected to an analysis to determine if they exhibit glaucoma indicators. Also, the images are put into a standard format. The system may include estimating the position of the optic cup by combining results from multiple optic cup segmentation techniques. The system may include estimating the position of the optic disc by applying edge detection to the funds image, excluding edge points that are unlikely to be optic disc boundary points, and estimating the position of an optic disc by fitting an ellipse to the remaining edge points.

    摘要翻译: 使用非立体眼底图像来获得多个青光眼指示符。 此外,用于受试者的基因组数据用于获得与与青光眼相关的一个或多个基因和/或SNP相关的遗传标记数据。 青光眼指标和遗传标记数据被输入到适应模型中,该模型用于产生指示受试者青光眼风险的输出。 综合来看,遗传指标和基因组数据对于青光眼的风险比孤立的两者之一更有信息。 自适应模型可以是两阶段模型,其具有第一阶段,其中通过第一自适应模型模块将个体遗传指标与基因组数据的相应部分组合以形成相应的第一输出,第二阶段中,第一输出是 通过第二自适应模式组合。 对眼底图像进行纹理分析,根据其质量对其进行分类,仅对满足质量标准的图像进行分析,以确定其是否呈现青光眼指标。 此外,图像被放入标准格式。 该系统可以包括通过组合来自多个光学杯分割技术的结果来估计光学杯的位置。 该系统可以包括通过对资金图像应用边缘检测来估计视盘的位置,排除不太可能是视盘边界点的边缘点,以及通过将椭圆拟合到剩余边缘点来估计视盘的位置 。

    Handwritten type electronic paper display and manufacturing method thereof

    公开(公告)号:US09830006B2

    公开(公告)日:2017-11-28

    申请号:US13700085

    申请日:2012-08-02

    申请人: Danna Song Zhuo Zhang

    发明人: Danna Song Zhuo Zhang

    摘要: Embodiments of the invention provide a handwritten type electronic paper display and a manufacture method thereof. The handwritten type electronic paper display comprises: a first electrode substrate (1) and a second electrode substrate (2) having a same pixel electrode matrix structure, an electronic paper thin film (3), a flexible printed circuit (4), a stylus (5) and an electrical source. The electronic paper thin film (3) is bonded onto an upper surface of the first electrode substrate (1), a common electrode of the electronic paper thin film is electrically connected to a negative electrode of the electrical source; the second electrode substrate (2) is fixed on the electronic paper thin film (3) in a thin film manner; the flexible printed circuit (4) is adapted for electrically connecting pixels of the first electrode substrate (1) to corresponding pixels of the second electrode substrate (2); and the stylus (5) is electrically connect to a positive electrode of the electrical source.

    Electronic handwriting screen
    6.
    发明授权

    公开(公告)号:US09759977B2

    公开(公告)日:2017-09-12

    申请号:US13701651

    申请日:2012-08-01

    申请人: Zhuo Zhang

    发明人: Zhuo Zhang

    摘要: The embodiments of present invention disclose an electronic handwriting screen and relate to the field of electrophoretic display techniques. In the embodiment of present invention, because insulation spacing elements are provided between the electrophonic display functional film and the bottom electrode, when an appropriate voltage is applied between the top electrode and the bottom electrode, the top electrode is pressed so as to make the electrophonic display functional film contact with the bottom electrode, which shortens the distance between the top electrode and the bottom electrode and further increases the electric field force acting on the charged colorant particles; as a result, electrophoresis effect occurs in the electrophoresis liquid so that patterns are displayed or erased at the pressing location, and handwriting function is thereby realized without a touch screen, reducing the manufacturing costs for an electronic handwriting screen.

    Polymer dispersed liquid crystal film and method for manufacturing the same
    7.
    发明授权
    Polymer dispersed liquid crystal film and method for manufacturing the same 有权
    聚合物分散液晶膜及其制造方法

    公开(公告)号:US09454030B2

    公开(公告)日:2016-09-27

    申请号:US13338461

    申请日:2011-12-28

    摘要: The disclosed technology involves a polymer dispersed liquid crystal film including: a first base substrate, a second base substrate, and a polymer dispersed liquid crystal film between the first base substrate and the second base substrate, wherein a first transparent conductive layer is formed on the first base substrate, the first transparent conductive layer is contacted with the first light permeable pressure-sensitive adhesive layer, and the polymer dispersed liquid crystal is adhered to the first base substrate through the first light permeable pressure-sensitive adhesive layer; and a second transparent conductive layer is formed on the second base substrate, the second transparent conductive layer is contacted with the second light permeable pressure-sensitive adhesive layer, and the polymer dispersed liquid crystal is adhered to the second base substrate through the second light permeable pressure-sensitive adhesive layer.

    摘要翻译: 所公开的技术涉及聚合物分散液晶膜,其包括:第一基底基板,第二基底基板和在第一基底基板和第二基底基板之间的聚合物分散液晶膜,其中在第一基底基板 第一基底基板,第一透明导电层与第一透光性粘合剂层接触,并且聚合物分散液晶通过第一透光性压敏粘合剂层粘附到第一基底基板; 在第二基底基板上形成第二透明导电层,第二透明导电层与第二透光性粘合剂层接触,通过第二透光性粘合剂层使聚合物分散液晶粘附于第二基材 压敏粘合剂层。

    Array substrate and manufacturing method thereof, active display
    8.
    发明授权
    Array substrate and manufacturing method thereof, active display 有权
    阵列基板及其制造方法,主动显示

    公开(公告)号:US08633069B2

    公开(公告)日:2014-01-21

    申请号:US13292320

    申请日:2011-11-09

    摘要: A manufacturing method for an array substrate comprising: sequentially forming a gate metal film, a gate insulating layer and an active layer film; applying photoresist, and patterning the photoresist; etching the stacked layers corresponding to a photoresist-completely-removed region; ashing to remove the photoresist in a photoresist-partially-remained region and remain a part of photoresist in a photoresist-completely-remained region, etching the gate insulating layer and the active layer film in the photoresist-partially-remained region; forming an insulating layer film; lifting off the photoresist and the insulating layer film thereon; forming a conductive film, and patterning the conductive film to from a source electrode, a drain electrode, a data line, a pixel electrode and an active layer channel.

    摘要翻译: 一种阵列基板的制造方法,包括:依次形成栅极金属膜,栅极绝缘层和有源层膜; 施加光致抗蚀剂,并图案化光致抗蚀剂; 蚀刻对应于光致抗蚀剂完全去除区域的堆叠层; 灰化以除去光致抗蚀剂部分保留区域中的光致抗蚀剂,并保留在光致抗蚀剂完全残留区域中的光致抗蚀剂的一部分,蚀刻光致抗蚀剂部分保留区域中的栅极绝缘层和有源层膜; 形成绝缘层膜; 在其上剥离光致抗蚀剂和绝缘层膜; 形成导电膜,并且从源电极,漏电极,数据线,像素电极和有源层通道构图导电膜。

    APPARATUS AND METHOD FOR DETECTING HIGH-ENERGY RADIATION
    9.
    发明申请
    APPARATUS AND METHOD FOR DETECTING HIGH-ENERGY RADIATION 审中-公开
    用于检测高能辐射的装置和方法

    公开(公告)号:US20110210262A1

    公开(公告)日:2011-09-01

    申请号:US12692448

    申请日:2010-01-22

    IPC分类号: G01T1/16

    摘要: An apparatus for spatially correcting an image frame is disclosed. In some embodiments, the apparatus stores a frame of pixel values and scans a multi-pixel correction window across the frame. Spatial correction is performed on pixels within the window at correction positions during the scan. The spatial correction comprises estimating pixel values at value estimation positions based on one or more pixel values within the window for pixels satisfying a logical condition. The value estimation positions correspond to pixel values which do not fall within the window again during the scan. Further disclosed is an apparatus for detecting high-energy radiation, in which integration circuitry is used for integrating charge responsive to radiation photon interaction events. The circuits are controllable in accordance with an exposure control signal to vary an exposure window duration according to an operating parameter of the apparatus.

    摘要翻译: 公开了一种用于空间校正图像帧的装置。 在一些实施例中,该装置存储一帧像素值,并跨越该帧扫描多像素校正窗口。 在扫描期间的校正位置处对窗口内的像素执行空间校正。 空间校正包括基于满足逻辑条件的像素在窗口内的一个或多个像素值来估计值估计位置处的像素值。 值估计位置对应于在扫描期间不再落入窗口内的像素值。 进一步公开的是一种用于检测高能辐射的装置,其中集成电路用于响应于辐射光子相互作用事件积分电荷。 电路根据曝光控制信号是可控的,以根据装置的操作参数改变曝光窗持续时间。

    Measuring test effects using adjusted outlier data
    10.
    发明授权
    Measuring test effects using adjusted outlier data 有权
    使用调整的异常值数据测量测试效果

    公开(公告)号:US08732528B1

    公开(公告)日:2014-05-20

    申请号:US13345378

    申请日:2012-01-06

    IPC分类号: G06F11/00

    摘要: This disclosure is directed to measuring test effects using adjusted outlier data. Test data and control data may include some outlier data (i.e., right-side tails of distribution curves), which may bias the resultant data. The outlier data may be adjusted to reduce bias. A cutoff point is selected along the distribution of data. Data below the cutoff is maintained and used to determine an effect of the data below the cutoff point. The effect of the data above the cutoff may be processed as follows. Predictor data is identified from the data below, but near, the cutoff point. The predictor data may then be used determine the effect of the outlier data that is above the cutoff point. In some embodiments, the predictor data may be weighted and combined with a weighted portion of the outlier data to determine an effect of the data above the cutoff point.

    摘要翻译: 本公开涉及使用调整的异常值数据测量测试效果。 测试数据和控制数据可以包括一些异常值数据(即,分布曲线的右侧尾部),其可能偏移所得到的数据。 可以调整异常值数据以减少偏差。 沿着数据分布选择一个截止点。 保留低于截止值的数据并用于确定数据低于截止点的影响。 可以如下处理截止值以上的数据的效果。 预测数据从下面的数据识别,但是在临界点附近。 然后可以使用预测器数据来确定高于截止点的离群值数据的影响。 在一些实施例中,预测器数据可以被加权并与异常值数据的加权部分组合以确定在截止点之上的数据的影响。