公开(公告)号：US4918222A

公开(公告)日：1990-04-17

申请号：US83397

申请日：1987-08-10

Applicant: Jiang-Jen Lin ,  John F. Knifton ,  Ernest L. Yeakey

Inventor： Jiang-Jen Lin ,  John F. Knifton ,  Ernest L. Yeakey

IPC: C07C231/00 ,  C07C233/46

CPC classification number: C07C231/00 ,  C07C233/46

Abstract: An N-acetylglycine is manufactured by reacting paraformaldehyde with an acetamide and carbon monoxide in the present of a cobalt-containing catalyst promoted by a sulfoxide or dinitride compounds. The presence of sulfoxide or dinitrile ligands are essential for the high yield synthesis of N-acetylglycine and good cobalt recovery.

Abstract translation: 通过使多聚甲醛与乙酰胺和一氧化碳反应，在由亚砜或二氮化硼化合物促进的含钴催化剂存在下制备N-乙酰甘氨酸。 亚砜或二腈配体的存在对于N-乙酰甘氨酸的高产率合成和良好的钴回收是必需的。

公开(公告)号：US4554364A

公开(公告)日：1985-11-19

申请号：US683547

申请日：1984-12-19

Applicant: John R. Sanderson ,  Ernest L. Yeakey ,  Jiang-Jen Lin

Inventor： John R. Sanderson ,  Ernest L. Yeakey ,  Jiang-Jen Lin

IPC: C07D317/20 ,  C07D317/00

CPC classification number: C07D317/20

Abstract: It has been surprisingly discovered in accordance with the present invention that when 1,3-dioxolane is reacted with formaldehyde in the presence of tert-butyl hydroperoxide and a cobalt initiator, the reaction preferentially involves an addition of the formaldehyde to the 2-methylene group of the 1,3-dioxolane with only minor reaction with the 4-methylene and 5-methylene groups of the 1,3-dioxolane whereby the reaction product that is formed contains significant quantities of 2-hydroxyalkyl-1,3-dioxolanes and only minimal amounts of the undesired methyl formate by-product. 2-Hydroxymethyl-1,3-dioxolane is hydrolyzed with comparative ease to ethylene glycol and the corresponding glycol aldehyde (CHO--CH.sub.2 --OH). The glycol aldehyde in turn can be catalytically hydrogenated to form additional quantities of ethylene glycol.

Abstract translation: 根据本发明令人惊奇地发现，当1,3-二氧戊环与甲醛在叔丁基过氧化氢和钴引发剂的存在下反应时，反应优先包括向2-亚甲基基团加入甲醛 的1,3-二氧戊环，与1,3-二氧戊环的4-亚甲基和5-亚甲基仅有很小的反应，由此形成的反应产物含有大量的2-羟基烷基-1,3-二氧戊环，仅含有 最少量的不需要的甲酸甲酯副产物。 相对于乙二醇和相应的二醇醛（CHO-CH2-OH），2-羟基甲基-1,3-二氧戊环水解。 二醇醛依次可以被催化氢化以形成额外量的乙二醇。

公开(公告)号：US4433176A

公开(公告)日：1984-02-21

申请号：US344429

申请日：1982-02-01

Applicant: Jiang-Jen Lin ,  John F. Knifton

Inventor： Jiang-Jen Lin ,  John F. Knifton

IPC: C07C29/32 ,  C07C45/49 ,  C07C47/06

CPC classification number: C07C29/32 ,  C07C45/49 ,  C12C11/02

Abstract: Acetaldehyde is prepared in good yield from methanol and synthesis gas under mild reaction conditions by contacting a mixture of methanol, carbon monoxide and hydrogen with an iodide or iodine free catalyst composition comprising (1) ruthenium powder, (2) a cobalt-containing compound (3) a rhodium-containing compound, and (4) an onium salt or base, and heating the resulting mixture under mild temperature and pressure for sufficient time to produce the desired acetaldehyde, and then recovering the same from the reaction mixture.

Abstract translation: 通过使甲醇，一氧化碳和氢气的混合物与碘化物或碘的催化剂组合物接触，在温和的反应条件下，从甲醇和合成气中以良好的产率制备乙醛，其包含（1）钌粉末，（2）含钴化合物 3）含铑化合物和（4）鎓盐或碱，并在温和的温度和压力下加热所得混合物足够的时间以产生所需的乙醛，然后从反应混合物中回收。

公开(公告)号：US4794199A

公开(公告)日：1988-12-27

申请号：US105462

申请日：1987-10-01

Applicant: Jiang-Jen Lin ,  John F. Knifton

Inventor： Jiang-Jen Lin ,  John F. Knifton

IPC: C07C85/08 ,  C07C85/18

CPC classification number: C07C209/60

Abstract: This invention concerns the synthesis of primary amines from olefins, synthesis gas and ammonia via an amination process in the presence of a cobalt catalyst, an ether solvent and a tertiary group VB donor ligand.

Abstract translation: 本发明涉及在钴催化剂，醚溶剂和叔组VB供体配体的存在下，通过胺化方法从烯烃，合成气和氨合成伯胺。

公开(公告)号：US4647691A

公开(公告)日：1987-03-03

申请号：US339233

申请日：1982-01-13

Applicant: Jiang-Jen Lin ,  John F. Knifton

Inventor： Jiang-Jen Lin ,  John F. Knifton

IPC: C07C27/06 ,  C07C67/36 ,  C07C69/12 ,  B01J31/00 ,  B01J31/02 ,  B01J31/16 ,  B01J31/20 ,  B01J31/24 ,  C07B61/00 ,  C07C27/00 ,  C07C29/15 ,  C07C29/151 ,  C07C29/157 ,  C07C31/02 ,  C07C31/04 ,  C07C31/08 ,  C07C31/10 ,  C07C31/12 ,  C07C51/00 ,  C07C51/10 ,  C07C53/08 ,  C07C53/122 ,  C07C67/00 ,  C07C69/003 ,  C07C69/22

CPC classification number: B01J31/2404 ,  B01J31/0268 ,  B01J31/20 ,  C07C29/1512 ,  C07C29/1514 ,  C07C29/157 ,  C07C31/04 ,  C07C31/08 ,  C07C31/10 ,  C07C31/12 ,  C07C51/10 ,  C07C67/36 ,  B01J2531/0208 ,  B01J2531/72 ,  B01J2531/74 ,  Y02P20/52

Abstract: Ethyl and n-propyl esters of carboxylic acids are prepared in good yield from methanol, syngas and a carboxylic acid by contacting a mixture of the carboxylic acid, carbon monoxide, hydrogen and methanol with a catalyst composition comprising a ruthenium-containing compound, a cobalt-containing compound and a quaternary onium salt or base, and heating the resulting mixture at an elevated temperature and pressure for sufficient time to produce the desired ethyl and propyl esters, and then recovering the same from the reaction mixture.

Abstract translation: 通过将羧酸，一氧化碳，氢气和甲醇的混合物与包含含钌化合物，钴的钴催化剂组合物接触，由甲醇，合成气和羧酸以良好的产率制备羧酸的乙基和正丙基酯 并且在升高的温度和压力下加热得到的混合物足够的时间以产生所需的乙基和丙酯，然后从反应混合物中回收它们。

公开(公告)号：US4529808A

公开(公告)日：1985-07-16

申请号：US576513

申请日：1984-02-02

Applicant: Jiang-Jen Lin ,  John F. Knifton

Inventor： Jiang-Jen Lin ,  John F. Knifton

IPC: B01J31/00 ,  B01J31/20 ,  B01J31/24 ,  C07B61/00 ,  C07D307/20

CPC classification number: C07D307/20

Abstract: A process is disclosed for preparing products such as 2-hydroxytetrahydrofuran which comprises contacting unsaturated compounds such as allyl alcohol with carbon monoxide and hydrogen in the presence of a rhodium carbonyl catalyst and a bi-solvent system. The bi-solvent system includes an aromatic solvent and an amide solvent and may be materials such as p-xylene and acetamide. Such a system provides for easy catalyst recovery since the rhodium catalyst is selectively soluble in the p-xylene whereas the desired product is conversely selectively soluble in the acetamide phase.

Abstract translation: 公开了用于制备诸如2-羟基四氢呋喃的产物的方法，其包括在羰基铑催化剂和双溶剂体系的存在下使不饱和化合物如烯丙醇与一氧化碳和氢气接触。 双溶剂系统包括芳族溶剂和酰胺溶剂，并且可以是诸如对二甲苯和乙酰胺的材料。 这种系统提供易于催化剂回收，因为铑催化剂选择性地可溶于对二甲苯，而所需产物相反地选择性地溶于乙酰胺相。

公开(公告)号：US4533742A

公开(公告)日：1985-08-06

申请号：US576509

申请日：1984-02-02

Applicant: Jiang-Jen Lin ,  John F. Knifton

Inventor： Jiang-Jen Lin ,  John F. Knifton

IPC: B01J31/00 ,  B01J31/20 ,  B01J31/24 ,  C07B61/00 ,  C07D307/20

CPC classification number: C07D307/20

Abstract: A process is disclosed for preparing products such as 2-hydroxytetrahydrofuran which comprises contacting unsaturated compounds such as allyl alcohol with carbon monoxide and hydrogen in the presence of a rhodium carbonyl catalyst and a ketone solvent system. Allyl alcohol conversions of 100% and selectivities to 2-hydroxytetrahydrofuran of 96% are achievable under certain conditions. Preferred ketone solvents are acetophenone and 2-undecanone. 2-Hydroxytetrahydrofuran is an important precursor to manufacture of 1,4-butanediol.

Abstract translation: 公开了一种制备诸如2-羟基四氢呋喃的产物的方法，该方法包括在羰基铑催化剂和酮溶剂体系的存在下使不饱和化合物如烯丙醇与一氧化碳和氢气接触。 100％的烯丙醇转化率和96％的2-羟基四氢呋喃的选择性在某些条件下是可以实现的。 优选的酮溶剂是苯乙酮和2-十一烷酮。 2-羟基四氢呋喃是制备1,4-丁二醇的重要前体。

公开(公告)号：US4451679A

公开(公告)日：1984-05-29

申请号：US435812

申请日：1982-10-21

Applicant: John F. Knifton ,  Jiang-Jen Lin ,  Robert A. Grigsby, Jr. ,  Walter H. Brader, Jr.

Inventor： John F. Knifton ,  Jiang-Jen Lin ,  Robert A. Grigsby, Jr. ,  Walter H. Brader, Jr.

IPC: C07C27/20 ,  B01J31/00 ,  B01J31/28 ,  C07B61/00 ,  C07C27/00 ,  C07C27/22 ,  C07C29/157 ,  C07C29/16 ,  C07C31/125 ,  C07C45/00 ,  C07C45/50 ,  C07C67/00

CPC classification number: B01J31/0268 ,  B01J31/0239 ,  B01J31/0284 ,  B01J31/0288 ,  B01J31/04 ,  B01J31/20 ,  B01J31/2208 ,  B01J31/28 ,  B01J31/30 ,  C07C29/16 ,  C07C31/125 ,  C07C45/50 ,  B01J2231/321 ,  B01J2531/0211 ,  B01J2531/821 ,  B01J31/2234

Abstract: This invention concerns a process of preparing alcohols and aldehydes which comprises the steps of contacting a mixture of terminal and/or internal olefins and synthesis gas with a catalyst system comprising a ruthenium-containing compound dispersed in a low melting quaternary phosphonium or ammonium base or salt and heating said resultant reaction mixture under a pressure of 100 psi or greater at a temperature of at least 50.degree. C. for a sufficient time to produce said alcohols and aldehydes.

Abstract translation: 本发明涉及一种制备醇和醛的方法，其包括以下步骤：使末端和/或内部烯烃和合成气的混合物与包含分散在低熔点季铵或铵碱或盐中的含钌化合物的催化剂体系相接触 并在100psi或更大的压力下在至少50℃的温度下加热所得的反应混合物足够的时间以产生所述的醇和醛。

公开(公告)号：US4371724A

公开(公告)日：1983-02-01

申请号：US224199

申请日：1981-01-08

Applicant: Jiang-Jen Lin ,  John F. Knifton

Inventor： Jiang-Jen Lin ,  John F. Knifton

IPC: B01J23/46 ,  B01J27/08 ,  B01J31/02 ,  B01J31/18 ,  B01J31/20 ,  B01J31/22 ,  B01J31/30 ,  C07C29/32 ,  C07C27/00

CPC classification number: C07C29/32 ,  B01J23/46 ,  B01J27/08 ,  B01J31/0239 ,  B01J31/0268 ,  B01J31/30 ,  B01J2531/821 ,  B01J31/20 ,  B01J31/2234 ,  Y02P20/52

Abstract: Ethanol is prepared by contacting methanol, hydrogen and carbon monoxide with a catalyst system comprising a ruthenium compound, a quaternary phosphonium or ammonium base or salt and a cobalt compound such as cobalt iodide in the presence of a non-polar, substantially inert, oxygenated hydrocarbon solvent.

Abstract translation: 乙醇是通过使甲醇，氢气和一氧化碳与包含钌化合物，季鏻或铵碱或盐的钴催化剂体系和钴化合物如碘化钴在非极性基本惰性的含氧烃 溶剂。

公开(公告)号：US4366259A

公开(公告)日：1982-12-28

申请号：US316195

申请日：1981-10-29

Applicant: John F. Knifton ,  Jiang-Jen Lin

Inventor： John F. Knifton ,  Jiang-Jen Lin

IPC: C07C27/06 ,  C07C67/36 ,  C07C69/12 ,  B01J31/00 ,  B01J31/02 ,  B01J31/16 ,  B01J31/20 ,  B01J31/24 ,  C07B61/00 ,  C07C27/00 ,  C07C29/15 ,  C07C29/151 ,  C07C29/157 ,  C07C31/02 ,  C07C31/04 ,  C07C31/08 ,  C07C31/10 ,  C07C31/12 ,  C07C51/00 ,  C07C51/10 ,  C07C53/08 ,  C07C53/122 ,  C07C67/00 ,  C07C69/003 ,  C07C69/22

CPC classification number: B01J31/2404 ,  B01J31/0268 ,  B01J31/20 ,  C07C29/1512 ,  C07C29/1514 ,  C07C29/157 ,  C07C31/04 ,  C07C31/08 ,  C07C31/10 ,  C07C31/12 ,  C07C51/10 ,  C07C67/36 ,  B01J2531/0208 ,  B01J2531/72 ,  B01J2531/74 ,  Y02P20/52

Abstract: This invention concerns a process of making acetic acid and propionic acid and their esters which comprises contacting a mixture of CO and H.sub.2 with a catalyst system comprising a ruthenium-containing compound and a cobalt halide dispersed in a low melting quaternary phosphonium or ammonium base or salt at a temperature of at least about 150.degree. C. and at a pressure of about 500 psig or greater.

Abstract translation: 本发明涉及一种制备乙酸和丙酸及其酯的方法，其包括使CO和H 2的混合物与包含钌的化合物和分散在低熔点季铵或铵碱或盐中的卤化钴的催化剂体系接触 在至少约150℃的温度和约500psig或更大的压力下。