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    METHOD AND APPARATUS TO USE MULTIPLE SPECTROSCOPIC ENVELOPES TO DETERMINE COMPONENTS WITH GREATER ACCURACY AND DYNAMIC RANGE
    2.
    发明申请
    METHOD AND APPARATUS TO USE MULTIPLE SPECTROSCOPIC ENVELOPES TO DETERMINE COMPONENTS WITH GREATER ACCURACY AND DYNAMIC RANGE 有权
    使用多个光谱包络来确定具有更大精度和动态范围的组件的方法和装置

    公开(公告)号：US20140042323A1

    公开(公告)日：2014-02-13

    申请号：US13984813

    申请日：2011-02-11

    申请人： Jing Shen ,  Christopher Michael Jones ,  Michael T. Pelletier

    发明人： Jing Shen ,  Christopher Michael Jones ,  Michael T. Pelletier

    IPC分类号： G01N21/25

    CPC分类号： G01N21/255 ,  E21B47/102 ,  E21B49/08 ,  G01N21/3577 ,  G01N21/359 ,  G01N33/2823 ,  G01N2201/129

    摘要： A method of using spectroscopic envelopes for determining components in a sample may include selecting spectroscopic envelopes and passing input light through a sample comprising at least one absorbing component is provided. The method includes measuring throughput light with a photo-detector and determining the concentration of the at least one absorbing component in the sample using the measured throughput, wherein at least one of the plurality of spectroscopic envelopes overlaps at least one absorption band of the at least one absorbing component in the sample. An apparatus for determining components in a sample including an input light source having a spectrum and a sample container having a fixed optical path-length is also provided. The apparatus may include a plurality of pre-selected spectroscopic envelopes to select spectral portions of the throughput light from the sample; and at least one photo-detector to measure the throughput light selected by the spectroscopic envelopes.

    摘要翻译： 使用用于确定样品中的组分的光谱包络的方法可以包括选择光谱包络并将输入光通过包含至少一个吸收组分的样品。 该方法包括使用光检测器测量通过量光，并使用测量的通量来确定样品中至少一种吸收组分的浓度，其中多个光谱包络中的至少一个与至少一个吸收组分的至少一个吸收带重叠 样品中的一种吸收组分。 还提供了一种用于确定样品中的组分的装置，其包括具有光谱的输入光源和具有固定的光程长度的样品容器。 该装置可以包括多个预先选择的光谱包络，以从样品中选择光通量光的部分; 以及至少一个光检测器来测量由光谱包络选择的通过量光。

    Spectroscopic nanosensor logging systems and methods
    6.
    发明授权
    Spectroscopic nanosensor logging systems and methods 有权
    光谱纳米传感器测井系统及方法

    公开(公告)号：US08921768B2

    公开(公告)日：2014-12-30

    申请号：US13636294

    申请日：2011-06-01

    申请人： Christopher M. Jones ,  Michael T. Pelletier ,  Jing Shen ,  Marian L. Morys

    发明人： Christopher M. Jones ,  Michael T. Pelletier ,  Jing Shen ,  Marian L. Morys

    IPC分类号： G01V5/00 ,  G01V5/04 ,  E21B47/10 ,  B82Y30/00 ,  G01N21/65 ,  E21B49/00

    CPC分类号： E21B47/102 ,  B82Y30/00 ,  E21B49/00 ,  G01N21/658 ,  G01V5/00

    摘要： Logging systems and methods that employ nanosensors to obtain spectral measurements downhole. The nanosensors can be dispersed in borehole fluids (including cement slurries) that circulate, diffuse, or get injected in a borehole. Because the nanosensors have diameters on the order of 10 nm to 1000 nm, they readily penetrate into cracks, pores, and other voids where their carrier fluids can reach. The nanosensors transport light sources and recording media to measure spectra in these otherwise inaccessible regions. The nanosensors are then recovered and analyzed to reconstruct the measured spectra and determine relevant material characteristics. Among other things, spectral measurements can reveal the presence of certain elements and molecules in the formation and fluids, from which information scientists determine composition and phases of formation fluids and the formation itself. Certain triggering criteria may also be employed to enable the nanosensor measurements to be associated with specific locations, paths, and/or events.

    摘要翻译： 使用纳米传感器在井下获取光谱测量的测井系统和方法。 纳米传感器可以分散在钻孔中的循环，扩散或注入的井眼流体​​（包括水泥浆）中。 因为纳米传感器的直径在10nm到1000nm之间，所以它们很容易渗透到其载体流体可以达到的裂纹，孔隙和其它空隙中。 纳米传感器传输光源和记录介质以测量这些其他不可接近区域的光谱。 然后回收和分析纳米传感器以重建测量的光谱并确定相关的材料特性。 除了别的以外，光谱测量可以揭示地层和流体中某些元素和分子的存在，信息科学家可以从这些元素和分子确定地层流体的组成和阶段以及地层本身。 还可以采用某些触发标准，以使纳米传感器测量与特定位置，路径和/或事件相关联。

    SPECTROSCOPIC NANOSENSOR LOGGING SYSTEMS AND METHODS
    7.
    发明申请
    SPECTROSCOPIC NANOSENSOR LOGGING SYSTEMS AND METHODS 有权
    光谱纳米传感器记录系统和方法

    公开(公告)号：US20130068940A1

    公开(公告)日：2013-03-21

    申请号：US13636294

    申请日：2011-06-01

    申请人： Christopher M. Jones ,  Michael T. Pelletier ,  Jing Shen ,  Marian L. Morys

    发明人： Christopher M. Jones ,  Michael T. Pelletier ,  Jing Shen ,  Marian L. Morys

    IPC分类号： E21B47/10

    CPC分类号： E21B47/102 ,  B82Y30/00 ,  E21B49/00 ,  G01N21/658 ,  G01V5/00

    摘要： Logging systems and methods that employ nanosensors to obtain spectral measurements downhole. The nanosensors can be dispersed in borehole fluids (including cement slurries) that circulate, diffuse, or get injected in a borehole. Because the nanosensors have diameters on the order of 10 nm to 1000 nm, they readily penetrate into cracks, pores, and other voids where their carrier fluids can reach. The nanosensors transport light sources and recording media to measure spectra in these otherwise inaccessible regions. The nanosensors are then recovered and analyzed to reconstruct the measured spectra and determine relevant material characteristics. Among other things, spectral measurements can reveal the presence of certain elements and molecules in the formation and fluids, from which information scientists determine composition and phases of formation fluids and the formation itself. Certain triggering criteria may also be employed to enable the nanosensor measurements to be associated with specific locations, paths, and/or events.

    摘要翻译： 使用纳米传感器在井下获取光谱测量的测井系统和方法。 纳米传感器可以分散在钻孔中的循环，扩散或注入的井眼流体​​（包括水泥浆）中。 因为纳米传感器的直径在10nm到1000nm之间，所以它们很容易渗透到其载体流体可以达到的裂纹，孔隙和其它空隙中。 纳米传感器传输光源和记录介质以测量这些其他不可接近区域的光谱。 然后回收和分析纳米传感器以重建测量的光谱并确定相关的材料特性。 除了别的以外，光谱测量可以揭示地层和流体中某些元素和分子的存在，信息科学家从这些元素和分子中可以确定地层流体的组成和阶段以及地层本身。 还可以采用某些触发标准，以使纳米传感器测量与特定位置，路径和/或事件相关联。

    EARLY DETECTION OF CANCER BY METHYLATED DNA IN BLOOD
    9.
    发明申请
    EARLY DETECTION OF CANCER BY METHYLATED DNA IN BLOOD 审中-公开
    通过甲基化DNA在血液中早期检测癌症

    公开(公告)号：US20100221723A1

    公开(公告)日：2010-09-02

    申请号：US12673416

    申请日：2008-08-13

    申请人： Regina Santella ,  Yu-Jing Zhang ,  Chien Jen Chen ,  Jing Shen

    发明人： Regina Santella ,  Yu-Jing Zhang ,  Chien Jen Chen ,  Jing Shen

    IPC分类号： C12Q1/68

    CPC分类号： C12Q1/6886 ,  C12Q2523/125 ,  C12Q2600/154

    摘要： This invention relates to early detection of cancer by detecting methylated DNA in blood. In one embodiment, there is provided a method of predicting the occurrence of hepatocellular carcinoma in a subject, comprising the steps of preparing DNA samples from blood samples of the subject; and determining methylation status of a group of genes comprising RASSF1A, p16 and p15, wherein hypermethylation of these genes as compared to normal control samples indicates the subject is likely to develop hepatocellular carcinoma in the future.

    摘要翻译： 本发明涉及通过检测血液中的甲基化DNA来早期检测癌症。 在一个实施方案中，提供了预测受试者中肝细胞癌发生的方法，包括从受试者血液样品中制备DNA样品的步骤; 并确定包含RASSF1A，p16和p15的一组基因的甲基化状态，其中与正常对照样品相比，这些基因的高甲基化表明受试者将来可能发展为肝细胞癌。

    Enhanced efficacy stable antiperspirant active solution and method of making same
    10.
    发明授权
    Enhanced efficacy stable antiperspirant active solution and method of making same 失效
    增强功效稳定的止汗活性溶液及其制备方法

    公开(公告)号：US5955064A

    公开(公告)日：1999-09-21

    申请号：US955056

    申请日：1997-10-21

    申请人： Rocco Giovanniello ,  Nelson Ayala ,  Jing Shen ,  Ketan Shah

    发明人： Rocco Giovanniello ,  Nelson Ayala ,  Jing Shen ,  Ketan Shah

    IPC分类号： C01F7/48 ,  A61K7/32 ,  A61K7/34 ,  A61K7/38

    CPC分类号： A61Q15/00 ,  A61K8/28 ,  A61K8/44 ,  A61K2800/58

    摘要： An enhanced antiperspirant active having improved stability and a process for preparing the enhanced antiperspirant active solution are disclosed, the process comprises blending an enhanced basic aluminum chlorohydrate antiperspirant active having a peak 4 content of at least 20% (Component A) with a zirconium hydroxychloride neutral amino acid complex (component B) and a conventional basic aluminum chloride (Component C) , the order of addition not being critical; wherein at least 10% by weight of the total aluminum being derived from Component A and about 90% to 10% of the aluminum being derived from Component C; thereby forming a stable antiperspirant active solution of enhanced efficacy, the overall concentration of reactants in solution being about 38% to 55% by weight.

    摘要翻译： 公开了具有改进的稳定性的增强的止汗剂活性物和制备增强的止汗剂活性溶液的方法，该方法包括将具有至少20％的峰4含量（组分A）的增强型碱式水合氯化铝止汗剂活性物与羟基氯化中间体 氨基酸复合物（组分B）和常规碱性氯化铝（组分C），加成顺序不是关键的; 其中至少10重量％的总铝衍生自组分A，约90％至10％的铝衍生自组分C; 从而形成稳定的止汗活性溶液，其效果增强，溶液中反应物的总浓度为约38-55重量％。