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1.FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS 有权
标题翻译: 通过使用可清除的荧光核反应终止子合成的四色DNA序列公开(公告)号:US20120021408A1
公开(公告)日:2012-01-26
申请号:US13023283
申请日:2011-02-08
申请人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
发明人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6869 , C12Q1/6823 , C12Q2565/631 , C12Q2523/107 , C12Q2523/319
摘要: This invention provides a process for sequencing single-stranded DNA by employing a nanopore and modified nucleotides.
摘要翻译: 本发明提供了通过使用纳米孔和修饰的核苷酸对单链DNA进行测序的方法。
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2.
公开(公告)号:US20190136308A1
公开(公告)日:2019-05-09
申请号:US15988321
申请日:2018-05-24
申请人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
发明人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
IPC分类号: C12Q1/6869 , C12Q1/6823
摘要: This invention provides a process for sequencing single-stranded DNA employing modified nucleotides.
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3.FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS 有权
标题翻译: 通过使用可清除的荧光核反应终止子合成的四色DNA序列公开(公告)号:US20140315191A1
公开(公告)日:2014-10-23
申请号:US14242487
申请日:2014-04-01
申请人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
发明人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6869 , C12Q1/6823 , C12Q2565/631 , C12Q2523/107 , C12Q2523/319
摘要: This invention provides a process for sequencing single-stranded DNA employing modified nucleotides.
摘要翻译: 本发明提供了使用修饰的核苷酸测序单链DNA的方法。
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4.Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators 有权
标题翻译: 通过使用可切割荧光核苷酸可逆终止子的合成进行四色DNA测序公开(公告)号:US08298792B2
公开(公告)日:2012-10-30
申请号:US13023283
申请日:2011-02-08
申请人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
发明人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
CPC分类号: C12Q1/6869 , C12Q1/6823 , C12Q2565/631 , C12Q2523/107 , C12Q2523/319
摘要: This invention provides a process for sequencing single-stranded DNA employing modified nucleotides.
摘要翻译: 本发明提供了使用修饰的核苷酸测序单链DNA的方法。
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5.FOUR-COLOR DNA SEQUENCING BY SYNTHESIS USING CLEAVABLE FLUORESCENT NUCLEOTIDE REVERSIBLE TERMINATORS 有权
标题翻译: 通过使用可清除的荧光核反应终止子合成的四色DNA序列公开(公告)号:US20100092952A1
公开(公告)日:2010-04-15
申请号:US12312903
申请日:2007-11-30
申请人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
发明人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6869 , C12Q1/6823 , C12Q2565/631 , C12Q2523/107 , C12Q2523/319
摘要: This invention provides a process for sequencing single-stranded DNA by employing a nanopore and modified nucleotides.
摘要翻译: 本发明提供了通过使用纳米孔和修饰的核苷酸对单链DNA进行测序的方法。
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6.
公开(公告)号:US20170114403A1
公开(公告)日:2017-04-27
申请号:US15354531
申请日:2016-11-17
申请人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
发明人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6869 , C12Q1/6823 , C12Q2565/631 , C12Q2523/107 , C12Q2523/319
摘要: This invention provides a process for sequencing single-stranded DNA employing modified nucleotides.
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7.Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators 有权
标题翻译: 通过使用可切割荧光核苷酸可逆终止子的合成进行四色DNA测序公开(公告)号:US07883869B2
公开(公告)日:2011-02-08
申请号:US12312903
申请日:2007-11-30
申请人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
发明人: Jingyue Ju , Dae Hyun Kim , Lanrong Bi , Qinglin Meng , Xiaoxu Li
CPC分类号: C12Q1/6869 , C12Q1/6823 , C12Q2565/631 , C12Q2523/107 , C12Q2523/319
摘要: This invention provides a process for sequencing single-stranded DNA by employing a nanopore and modified nucleotides.
摘要翻译: 本发明提供了使用修饰的核苷酸测序单链DNA的方法。
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公开(公告)号:US09738922B2
公开(公告)日:2017-08-22
申请号:US14578125
申请日:2014-12-19
申请人: Timothy H. Bestor , John R. Edwards , Jingyue Ju , Xiaoxu Li
发明人: Timothy H. Bestor , John R. Edwards , Jingyue Ju , Xiaoxu Li
CPC分类号: C12Q1/6806 , C07H19/23 , C12Q1/6827 , C12Q1/6874 , C12Q2521/125 , C12Q2527/125 , C12Q2537/164
摘要: This invention provides methods of derivatizing a double-stranded DNA comprising contacting double-stranded DNA with a CpG methyltransferase and an s-adenosylmethionine analog. This invention also provides methods of sequencing DNA to determine methylation patterns.
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9.
公开(公告)号:US20220177959A1
公开(公告)日:2022-06-09
申请号:US17436513
申请日:2020-03-05
申请人: Jingyue Ju , Carl W. Fuller , Shiv Kumar , Sergey Kalachikov , Xiaoxu Li , Irina Morozova , James Russo , Steffen Jockusch
发明人: Jingyue Ju , Carl W. Fuller , Shiv Kumar , Sergey Kalachikov , Xiaoxu Li , Irina Morozova , James Russo , Steffen Jockusch
IPC分类号: C12Q1/6869
摘要: Disclosed herein are highly accurate approaches for single molecule electronic nanopore-based SBS.
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公开(公告)号:US11085076B2
公开(公告)日:2021-08-10
申请号:US15763364
申请日:2016-09-28
申请人: Jingyue Ju , Xiaoxu Li , Xin Chen , Zengmin Li , Shiv Kumar , Shundi Shi , Cheng Guo , Jianyi Ren , Min-Kang Hsieh , Minchen Chien , Chuanjuan Tao , Ece Erturk , Sergey Kalachikov , James J. Russo
发明人: Jingyue Ju , Xiaoxu Li , Xin Chen , Zengmin Li , Shiv Kumar , Shundi Shi , Cheng Guo , Jianyi Ren , Min-Kang Hsieh , Minchen Chien , Chuanjuan Tao , Ece Erturk , Sergey Kalachikov , James J. Russo
IPC分类号: C12Q1/68 , C07H19/10 , C07H19/14 , C07H19/20 , C12Q1/6869
摘要: Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof in the sequencing of a nucleic acid.
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