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公开(公告)号:US20050252990A1
公开(公告)日:2005-11-17
申请号:US11165496
申请日:2005-06-24
申请人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
发明人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
IPC分类号: A61M11/00 , A47K5/12 , A61M15/00 , B05B9/043 , B05B11/00 , B05B11/06 , B65D83/76 , F04B9/14 , F04B53/10 , F04B53/12 , F16K20060101
CPC分类号: A61M15/0065 , A61M15/00 , A61M15/0068 , A61M15/0071 , A61M15/0081 , A61M2205/7545 , B05B11/00412 , B05B11/3001 , B05B11/3067 , B05B11/308 , B05B11/309 , B05B11/3091 , F04B53/125 , Y10T137/7909 , Y10T137/7913 , Y10T137/7916
摘要: A miniaturized device for pressurizing fluid. The device includes a hollow piston that provides a fluid path and a valve member. The valve member is configured for axial movement so that the valve axis remains parallel to the piston axis. The valve member is arranged at one end of the hollow piston. The valve member may be partially or completely disposed within the hollow piston. The device is particularly adapted for use in a mechanically operated atomizer to produce an inhalable aerosol of a liquid medicament without the use of propellant gas.
摘要翻译: 用于加压流体的小型化装置。 该装置包括提供流体路径和阀构件的中空活塞。 阀构件被构造成用于轴向移动,使得阀轴保持平行于活塞轴线。 阀构件设置在中空活塞的一端。 阀构件可以部分地或完全地设置在中空活塞内。 该装置特别适用于机械操作的雾化器,以在不使用推进剂气体的情况下产生液体药物的可吸入气溶胶。
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公开(公告)号:US06497373B2
公开(公告)日:2002-12-24
申请号:US10143006
申请日:2002-05-13
申请人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
发明人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
IPC分类号: B05B9043
CPC分类号: A61M15/0065 , A61M15/00 , A61M15/0068 , A61M15/0071 , A61M15/0081 , A61M2205/7545 , B05B11/00412 , B05B11/3001 , B05B11/3067 , B05B11/308 , B05B11/309 , B05B11/3091 , F04B53/125 , Y10T137/7909 , Y10T137/7913 , Y10T137/7916
摘要: A miniaturized device for pressurizing fluid. The device includes a hollow piston that provides a fluid path and a valve member. The valve member is configured for axial movement so that the valve axis remains parallel to the piston axis. The valve member is arranged at one end of the hollow piston. The valve member may be partially or completely disposed within the hollow piston. The device is particularly adapted for use in a mechanically operated atomizer to produce an inhalable aerosol of a liquid medicament without the use of propellant gas.
摘要翻译: 用于加压流体的小型化装置。 该装置包括提供流体路径和阀构件的中空活塞。 阀构件被构造成用于轴向移动,使得阀轴保持平行于活塞轴线。 阀构件设置在中空活塞的一端。 阀构件可以部分地或完全地设置在中空活塞内。 该装置特别适用于机械操作的雾化器,以在不使用推进剂气体的情况下产生液体药物的可吸入气溶胶。
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公开(公告)号:US06402055B1
公开(公告)日:2002-06-11
申请号:US09354663
申请日:1999-07-16
申请人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
发明人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
IPC分类号: B05B9043
CPC分类号: A61M15/0065 , A61M15/00 , A61M15/0068 , A61M15/0071 , A61M15/0081 , A61M2205/7545 , B05B11/00412 , B05B11/3001 , B05B11/3067 , B05B11/308 , B05B11/309 , B05B11/3091 , F04B53/125 , Y10T137/7909 , Y10T137/7913 , Y10T137/7916
摘要: A miniaturized device for pressurizing fluid. The device includes a hollow piston that provides a fluid path and a valve member. The valve member is configured for axial movement so that the valve axis remains parallel to the piston axis. The valve member is arranged at one end of the hollow piston. The valve member may be partially or completely disposed within the hollow piston. The device is particularly adapted for use in a mechanically operated atomizer to produce an inhalable aerosol of a liquid medicament without the use of propellant gas.
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公开(公告)号:US06918547B2
公开(公告)日:2005-07-19
申请号:US10807447
申请日:2004-03-24
申请人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
发明人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
IPC分类号: A61M11/00 , A47K5/12 , A61M15/00 , B05B9/043 , B05B11/00 , B05B11/06 , B65D83/76 , F04B9/14 , F04B53/10 , F04B53/12 , F16K20060101
CPC分类号: A61M15/0065 , A61M15/00 , A61M15/0068 , A61M15/0071 , A61M15/0081 , A61M2205/7545 , B05B11/00412 , B05B11/3001 , B05B11/3067 , B05B11/308 , B05B11/309 , B05B11/3091 , F04B53/125 , Y10T137/7909 , Y10T137/7913 , Y10T137/7916
摘要: A miniaturized device for producing high pressure in a fluid imposes stringent requirements on the manufacturing process.The device according to the invention consists of a hollow piston displaceably mounted in a cylinder and a valve member which is guided by the hollow piston and mounted so as to be axially movable relative to the hollow piston. The valve member is arranged at one end of the hollow piston inside or immediately in front of the end of the hollow piston.The device is used in a mechanically operated high pressure atomizer. This consists of a two part housing which comprises a pump housing with nozzle, a blocking mechanism, a spring housing with spring, a non-pressurized storage container for the fluid and a medical counter integrated in the spring housing.The valve operates without any auxiliary force, closes very rapidly and is sealed tight against high pressure. The atomizer is safe and simple to operate and environmentally friendly. The fluid is metered extremely accurately.The atomizer is used, for example, to produce an inhalable aerosol of a liquid medicament without the use of propellant gas, at 320 bar, for example.
摘要翻译: 用于在流体中产生高压的小型化装置对制造过程施加了严格的要求。 根据本发明的装置包括可移动地安装在气缸中的中空活塞和由中空活塞引导并安装成可相对于中空活塞轴向移动的阀构件。 阀构件布置在中空活塞的一端处于中空活塞的端部的内部或紧邻中空活塞端部的前方。 该设备用于机械操作的高压雾化器。 这包括两部分壳体,其包括具有喷嘴的泵壳体,阻塞机构,具有弹簧的弹簧壳体,用于流体的非加压存储容器和集成在弹簧壳体中的医疗计数器。 阀门没有任何辅助作用力,非常快速地关闭,并在高压下密封。 雾化器操作安全,操作简单,环保。 流体测量非常准确。 例如,雾化器用于例如在320巴下产生液体药物的可吸入气溶胶,而不使用推进剂气体。
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公开(公告)号:US07104470B2
公开(公告)日:2006-09-12
申请号:US11165496
申请日:2005-06-24
申请人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
发明人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
IPC分类号: B05B9/043
CPC分类号: A61M15/0065 , A61M15/00 , A61M15/0068 , A61M15/0071 , A61M15/0081 , A61M2205/7545 , B05B11/00412 , B05B11/3001 , B05B11/3067 , B05B11/308 , B05B11/309 , B05B11/3091 , F04B53/125 , Y10T137/7909 , Y10T137/7913 , Y10T137/7916
摘要: A miniaturized device for pressurizing fluid. The device includes a hollow piston that provides a fluid path and a valve member. The valve member is configured for axial movement so that the valve axis remains parallel to the piston axis. The valve member is arranged at one end of the hollow piston. The valve member may be partially or completely disposed within the hollow piston. The device is particularly adapted for use in a mechanically operated atomizer to produce an inhalable aerosol of a liquid medicament without the use of propellant gas.
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公开(公告)号:US06726124B2
公开(公告)日:2004-04-27
申请号:US10292470
申请日:2002-11-13
申请人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
发明人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
IPC分类号: B05B9043
CPC分类号: A61M15/0065 , A61M15/00 , A61M15/0068 , A61M15/0071 , A61M15/0081 , A61M2205/7545 , B05B11/00412 , B05B11/3001 , B05B11/3067 , B05B11/308 , B05B11/309 , B05B11/3091 , F04B53/125 , Y10T137/7909 , Y10T137/7913 , Y10T137/7916
摘要: A miniaturized device for pressurizing fluid. The device includes a hollow piston that provides a fluid path and a valve member. The valve member is configured for axial movement so that the valve axis remains parallel to the piston axis. The valve member is arranged at one end of the hollow piston. The valve member may be partially or completely disposed within the hollow piston. The device is particularly adapted for use in a mechanically operated atomizer to produce an inhalable aerosol of a liquid medicament without the use of propellant gas.
摘要翻译: 用于加压流体的小型化装置。 该装置包括提供流体路径和阀构件的中空活塞。 阀构件被构造成用于轴向移动,使得阀轴保持平行于活塞轴线。 阀构件设置在中空活塞的一端。 阀构件可以部分地或完全地设置在中空活塞内。 该装置特别适用于机械操作的雾化器,以在不使用推进剂气体的情况下产生液体药物的可吸入气溶胶。
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公开(公告)号:US20060285987A1
公开(公告)日:2006-12-21
申请号:US11463455
申请日:2006-08-09
申请人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
发明人: Joachim Jaeger , Pasquale Cirillo , Joachim Eicher , Johannes Geser , Bernhard Freund , Bernd Zierenberg
IPC分类号: F04B39/00
CPC分类号: A61M15/0065 , A61M15/00 , A61M15/0068 , A61M15/0071 , A61M15/0081 , A61M2205/7545 , B05B11/00412 , B05B11/3001 , B05B11/3067 , B05B11/308 , B05B11/309 , B05B11/3091 , F04B53/125 , Y10T137/7909 , Y10T137/7913 , Y10T137/7916
摘要: A miniaturized device for pressurizing fluid. The device includes a hollow piston that provides a fluid path and a valve member. The valve member is configured for axial movement so that the valve axis remains parallel to the piston axis. The valve member is arranged at one end of the hollow piston. The valve member may be partially or completely disposed within the hollow piston. The device is particularly adapted for use in a mechanically operated atomizer to produce an inhalable aerosol of a liquid medicament without the use of propellant gas.
摘要翻译: 用于加压流体的小型化装置。 该装置包括提供流体路径和阀构件的中空活塞。 阀构件被构造成用于轴向移动,使得阀轴保持平行于活塞轴线。 阀构件设置在中空活塞的一端。 阀构件可以部分地或完全地设置在中空活塞内。 该装置特别适用于机械操作的雾化器,以在不使用推进剂气体的情况下产生液体药物的可吸入气溶胶。
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公开(公告)号:US07963955B2
公开(公告)日:2011-06-21
申请号:US10754499
申请日:2004-01-12
申请人: Bernhard Freund , Dieter Hochrainer , Heinrich Kladders , Bernd Zierenberg , Joachim Eicher , Johannes Geser , Martin Essing , Holger Reinecke
发明人: Bernhard Freund , Dieter Hochrainer , Heinrich Kladders , Bernd Zierenberg , Joachim Eicher , Johannes Geser , Martin Essing , Holger Reinecke
IPC分类号: A61B19/00
CPC分类号: B65D83/0061 , E05F3/10 , E05F3/102 , E05Y2900/602
摘要: Foil bags are used as a primary packaging for liquids, the bags permitting the liquid to be taken therefrom without the application of a considerable amount of force. A container is provided for a medicinal liquid, the container being gas-tight and liquid-tight so that it is storable over many months. The container includes a collapsible foil bag on which a flange, which is stable in respect of shape, is disposed. The flange is designed for fitting onto a discharge connection member. The container can be disposed in a casing which is stable in respect of shape. The medicinal liquid does not come into contact with air and is protected from the effect of light. The medicinal liquid may be dispensed from the foil bag in many partial quantities over a prolonged period of time, with a respective partial amount thereof being converted into an aerosol by means of an atomizer.
摘要翻译: 箔袋用作液体的主要包装,允许从其中取出液体的袋不施加相当大的力。 为药液提供容器,该容器是气密和液密的,以便可以在几个月内储存。 容器包括可折叠的箔袋,其上设置有关于形状稳定的凸缘。 凸缘设计用于安装在排放连接构件上。 容器可以设置在相对于形状稳定的壳体中。 药用液体不会与空气接触并被保护免受光线的影响。 医药液体可以在较长的时间段内以多个部分量从箔袋中分配,其相应的部分量通过雾化器转化成气溶胶。
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公开(公告)号:US06685691B1
公开(公告)日:2004-02-03
申请号:US09258357
申请日:1999-02-26
申请人: Bernhard Freund , Dieter Hochrainer , Heinrich Kladders , Bernd Zierenberg , Joachim Eicher , Johannes Geser , Martin Essing , Holger Reinecke
发明人: Bernhard Freund , Dieter Hochrainer , Heinrich Kladders , Bernd Zierenberg , Joachim Eicher , Johannes Geser , Martin Essing , Holger Reinecke
IPC分类号: A61B1900
CPC分类号: A61J1/10 , A61J1/14 , A61M2207/00 , B65D75/5877 , B65D75/5883 , B65D83/0061 , B65D83/62 , B65D2575/583
摘要: Foil bags are used as a primary packaging for liquids, the bags permitting the liquid to be taken therefrom without the application of a considerable amount of force. A container is provided for a medicinal liquid, the container being gas-tight and liquid-tight so that it is storable over many months. The container includes a collapsible foil bag on which a flange, which is stable in respect of shape, is disposed. The flange is designed for fitting onto a discharge connection member. The container can be disposed in a casing which is stable in respect of shape. The medicinal liquid does not come into contact with air and is protected from the effect of light. The medicinal liquid may be dispensed from the foil bag in many partial quantities over a prolonged period of time, with a respective partial amount thereof being converted into an aerosol by means of an atomizer.
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公开(公告)号:US20060016449A1
公开(公告)日:2006-01-26
申请号:US11232896
申请日:2005-09-23
申请人: Joachim Eicher , Johannes Geser , Matthias Hausmann , Michael Schyra , Gilbert Wuttke , Andreas Fiol , Heinrich Kladders , Dieter Hochrainer , Bernd Zierenberg
发明人: Joachim Eicher , Johannes Geser , Matthias Hausmann , Michael Schyra , Gilbert Wuttke , Andreas Fiol , Heinrich Kladders , Dieter Hochrainer , Bernd Zierenberg
IPC分类号: A61M11/00
CPC分类号: B05B11/0054 , A61M15/0065 , B05B11/0008 , B05B11/00412 , B05B11/0044 , B05B11/00444 , B05B11/00446
摘要: For meteredly dispensing a liquid over a period of several months from a container which can be stored over a long period of time, the need is for a container which is practically diffusion-tight and in which the liquid does not come into contact with the ambient atmosphere. The cartridge according to the invention is a three-shell container comprising a collapsible bag which contains the liquid, a container which is stable in respect of shape and a stiff metal casing. The cartridge can be releasably connected to a dispensing device. The cartridge can be provided with a micro-opening with which the time for pressure equalisation between the cartridge and the ambient atmosphere can be adjusted. The cartridge is suitable for aqueous and for alcoholic liquids which contain a pharmaceutically active substance. The liquid in the cartridge is protected from external influences. The cartridge can be used in an atomiser for producing an inhalable aerosol for the treatment of illnesses.
摘要翻译: 对于可以长时间储存的容器在几个月的时间内计量分配液体,需要一种几乎不扩散的容器,其中液体不会与环境接触 大气层。 根据本发明的墨盒是一种三壳容器,其包括容纳液体的可折叠袋,相对于形状稳定的容器和刚性金属外壳。 盒可以可释放地连接到分配装置。 墨盒可以设置有微孔,可以调节墨盒和环境大气之间的压力均衡时间。 该药筒适用于含有药物活性物质的水溶液和含酒精液体。 保护盒中的液体免受外部影响。 墨盒可用于雾化器中,用于产生用于治疗疾病的可吸入气雾剂。
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