Method for detecting thyroid carcinoma
    1.
    发明授权
    Method for detecting thyroid carcinoma 有权
    检测甲状腺癌的方法

    公开(公告)号:US09229003B2

    公开(公告)日:2016-01-05

    申请号:US12503434

    申请日:2009-07-15

    摘要: It is an object of the present invention to identify a gene that exhibits behavior which is characteristic of carcinomas such as thyroid carcinoma, so as to provide a method for detecting carcinoma and a cell growth suppressing agent. The present invention provides a method for detecting carcinoma, which comprises detecting malignant transformation by detecting at least one alteration of gene existing in chromosomal regions 1q41, 3q28, 7q31.2, 8p12, 8q22.2, 8q24.21, 11q4.1, 17q12, 20q11, 9p21.3, 16q13.2, and 16q23.1 in a specimen.

    摘要翻译: 本发明的目的是鉴定表现出甲状腺癌等癌症特征的基因,从而提供检测癌症和细胞生长抑制剂的方法。 本发明提供了一种检测癌症的方法,其包括通过检测染色体区域1q41,3q28,7q31.2,8p12,8q22.2,8q24.21,11q4.1,17q12中存在的基因的至少一个改变来检测恶性转化 ,20q11,9p21.3,16q13.2和16q23.1。

    METHOD FOR DETECTING THYROID CARCINOMA
    2.
    发明申请
    METHOD FOR DETECTING THYROID CARCINOMA 有权
    检测甲状腺癌的方法

    公开(公告)号:US20100035262A1

    公开(公告)日:2010-02-11

    申请号:US12503434

    申请日:2009-07-15

    摘要: It is an object of the present invention to identify a gene that exhibits behavior which is characteristic of carcinomas such as thyroid carcinoma, so as to provide a method for detecting carcinoma and a cell growth suppressing agent. The present invention provides a method for detecting carcinoma, which comprises detecting malignant transformation by detecting at least one alteration of gene existing in chromosomal regions 1q41, 3q28, 7q31.2, 8p12, 8q22.2, 8q24.21, 11q4.1, 17q12, 20q11, 9p21.3, 16q13.2, and 16q23.1 in a specimen.

    摘要翻译: 本发明的目的是鉴定表现出甲状腺癌等癌症特征的基因,从而提供检测癌症和细胞生长抑制剂的方法。 本发明提供了一种检测癌症的方法,其包括通过检测染色体区域1q41,3q28,7q31.2,8p12,8q22.2,8q24.21,11q4.1,17q12中存在的基因的至少一个改变来检测恶性转化 ,20q11,9p21.3,16q13.2和16q23.1。

    Method for detecting ovarian cancer and method for suppressing the same
    5.
    发明申请
    Method for detecting ovarian cancer and method for suppressing the same 有权
    检测卵巢癌的方法及其抑制方法

    公开(公告)号:US20090075277A1

    公开(公告)日:2009-03-19

    申请号:US12153967

    申请日:2008-05-28

    摘要: ABSTRACT An object of the present invention is to provide a method for detecting cancer through identification of genes exhibiting characteristic behavior in the cases of cancer such as ovarian cancer, and a cell growth inhibitor. The present invention provides a method for detecting cancer, which comprises detecting canceration including malignancy of a specimen through detection of at least one alteration of a gene existing in a chromosomal region 2q14. 2, 3p24. 1, 3q26. 2, 3q29, 4q34. 2, 6q23, 9p21. 3, 11q13. 3, 13q22.1, 13q33. 1, 13q33. 3, 15q12, 15q15. 1, 17p12, 17p13. 1, 17p13. 3, 18q21. 1, 18q21. 2, 18q21. 31, 18q21. 32, 18q21. 33, 18q23, 20q13. 13, 20q13. 2, 20q13. 31, 20q13. 33, Xp11. 23, Xp13.1, Xp13. 3, Xp26. 2, Xp26. 3, or Xq28 in the specimen.

    摘要翻译: 摘要本发明的目的是提供一种通过鉴定在诸如卵巢癌等癌症和细胞生长抑制剂的情况下表现出特征性行为的基因来检测癌症的方法。 本发明提供了一种检测癌症的方法,其包括通过检测染色体区域2q14中存在的基因的至少一个改变来检测包括恶性肿瘤的癌症。 2,3p24。 1,3q26。 2,3q29,4q34。 2,6q23,9p21。 3,11q13。 3,13q22.1,13q33。 1,13q33。 3,15q12,15q15。 1,17p12,17p13。 1,17p13。 3,18q21。 1,18q21。 2,18q21。 31,18q21。 32,18q21。 33,18q23,20q13。 13,20q13。 2,20q13。 31,20q13。 33,Xp11。 23,Xp13.1,Xp13。 3,Xp26。 2,Xp26。 3或Xq28。

    Method for detecting gastric cancer by detecting VLDLR gene
    7.
    发明申请
    Method for detecting gastric cancer by detecting VLDLR gene 审中-公开
    检测VLDLR基因检测胃癌的方法

    公开(公告)号:US20090054245A1

    公开(公告)日:2009-02-26

    申请号:US11785683

    申请日:2007-04-19

    IPC分类号: C40B30/00 C12Q1/68

    CPC分类号: C12Q1/6886 C12Q2600/154

    摘要: It is an objective of the present invention to provide a highly stable and reproducible method for detecting gastric cancer, by finding a novel gastric cancer-related gene and detecting the inactivation of such cancer-related gene. The present invention provides a method for detecting gastric cancer, comprising detecting malignant transformation of a gastric tissue cell by detecting the inactivation of the human VLDLR gene in the gastric tissue cell.

    摘要翻译: 本发明的目的是提供一种用于检测胃癌的高度稳定和可重现的方法,通过发现新的胃癌相关基因并检测这种癌症相关基因的失活。 本发明提供了一种检测胃癌的方法,包括通过检测胃组织细胞中人VLDLR基因的失活来检测胃组织细胞的恶性转化。

    METHOD FOR ANALYSIS USING NUCLEIC ACID MICROARRAY
    10.
    发明申请
    METHOD FOR ANALYSIS USING NUCLEIC ACID MICROARRAY 有权
    使用核酸微量分析的方法

    公开(公告)号:US20110105357A1

    公开(公告)日:2011-05-05

    申请号:US12994718

    申请日:2009-05-27

    IPC分类号: C40B30/04 G06F19/00

    摘要: An analytical method aided with a nucleic acid microarray, the nucleic acid microarray having a spot (X 1) onto which a first probe nucleic acid is immobilized, the method includes: allowing a labeled sample nucleic acid (A 1) of a sample to be tested to hybridize with the first probe nucleic acid; providing the spot (X 1) with a labeled verification nucleic acid (B) that has a sequence capable of hybridizing with at least a part of the first probe nucleic acid and is labeled with a label different from the labeled sample nucleic acid (A 1), and allowing the labeled verification nucleic acid (B) to hybridize with at least the first probe nucleic acid at all spots; measuring a labeled quantity value (F 1) of the labeled sample nucleic acid (A 1); and measuring a labeled quantity value (Fc 1) of the labeled verification nucleic acid (B).

    摘要翻译: 一种利用核酸微阵列辅助的分析方法,所述核酸微阵列具有固定有第一探针核酸的点(X 1),所述方法包括:使样品的标记样品核酸(A 1)为 测试与第一探针核酸杂交; 向斑点(X 1)提供具有能够与至少一部分第一探针核酸杂交的序列并用不同于标记的样品核酸(A 1)标记的标记的核酸核酸(B) ),并且允许标记的验证核酸(B)在所有点与至少第一探针核酸杂交; 测量标记的样品核酸(A 1)的标记量值(F 1); 并测量标记的验证核酸(B)的标记量值(Fc 1)。