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公开(公告)号：US5939082A
公开(公告)日：1999-08-17
申请号：US834010
申请日：1997-04-11
IPC分类号： A61K8/42 , A61K8/63 , A61K8/67 , A61K8/97 , A61Q1/02 , A61Q5/02 , A61Q5/12 , A61Q19/00 , A61Q19/08 , A61Q19/10 , A61K7/48
CPC分类号： A61Q19/00 , A61K8/42 , A61K8/63 , A61K8/671 , A61K8/673 , A61K8/675 , A61K8/97 , A61Q19/10 , A61Q1/02 , A61Q19/08 , A61Q5/02 , A61Q5/12 , Y10S514/844 , Y10S514/845 , Y10S514/846 , Y10S514/938
摘要： The present invention relates to topical compositions comprising a vitamin B.sub.3 compound which are useful for regulating skin condition, especially for regulating the signs of skin aging.
摘要翻译： 本发明涉及包含维生素B3化合物的局部组合物，其可用于调节皮肤状况，特别是用于调节皮肤老化的迹象。
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公开(公告)号：US06238678B1
公开(公告)日：2001-05-29
申请号：US09039750
申请日：1998-03-16
IPC分类号： A61K600
CPC分类号： A61K8/42 , A61K8/63 , A61K8/671 , A61K8/673 , A61K8/675 , A61K8/97 , A61Q1/02 , A61Q5/02 , A61Q5/12 , A61Q19/00 , A61Q19/08 , A61Q19/10 , Y10S514/844 , Y10S514/847 , Y10S514/887 , Y10S514/944
摘要： The present invention relates to topical compositions comprising a vitamin B3 compound which are useful for regulating skin condition, especially for regulating the signs of skin aging.
摘要翻译： 本发明涉及包含维生素B3化合物的局部组合物，其可用于调节皮肤状况，特别是用于调节皮肤老化的迹象。
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公开(公告)号：US06217888B1
公开(公告)日：2001-04-17
申请号：US09328578
申请日：1999-06-09
IPC分类号： A61K700
CPC分类号： A61Q19/00 , A61K8/42 , A61K8/63 , A61K8/671 , A61K8/673 , A61K8/675 , A61K8/97 , A61Q1/02 , A61Q5/02 , A61Q5/12 , A61Q19/08 , A61Q19/10 , Y10S514/844 , Y10S514/845 , Y10S514/846 , Y10S514/938
摘要： The present invention relates to topical compositions comprising a vitamin B3 compound which are useful for regulating skin condition, especially for regulating the signs of skin aging.
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4.发明授权
公开(公告)号：US5833998A
公开(公告)日：1998-11-10
申请号：US554067
申请日：1995-11-06
IPC分类号： A61K8/30 , A61K8/00 , A61K8/42 , A61K8/49 , A61K8/67 , A61Q1/00 , A61Q1/02 , A61Q1/12 , A61Q5/00 , A61Q5/02 , A61Q5/12 , A61Q19/00 , A61Q19/10 , A61K7/48
CPC分类号： A61Q19/10 , A61K8/42 , A61K8/673 , A61K8/675 , A61Q19/00 , A61Q1/02 , A61Q5/02 , A61Q5/12 , Y10S514/844 , Y10S514/846 , Y10S514/944
摘要： Disclosed are topical compositions for regulating the oily and/or shiny appearance of skin. The compositions contain: (a) an active for regulating the oily and/or shiny appearance of skin, said active consisting essentially of one or more compounds selected from the group consisting of niacinamide, pyridoxine, panthenol, and pantothenic acid, in an amount that is safe and effective for regulating the oily and/or shiny appearance of the skin; and (b) a cosmetically acceptable carrier for said active. Also disclosed are methods of regulating the oily and/or shiny appearance of skin by topical application of such compositions.
摘要翻译： 公开了用于调节皮肤油性和/或光泽外观的局部组合物。 所述组合物包含：（a）用于调节皮肤的油性和/或光泽外观的活性物质，所述活性物基本上由一种或多种选自烟酰胺，吡哆醇，泛醇和泛酸的化合物组成，其量为 对于调节皮肤的油性和/或光泽外观是安全和有效的; 和（b）用于所述活性物质的化妆品可接受载体。 还公开了通过局部施用这种组合物调节皮肤的油性和/或光泽外观的方法。
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公开(公告)号：US06183761B2
公开(公告)日：2001-02-06
申请号：US09267852
申请日：1999-03-12
IPC分类号： A61K600
CPC分类号： A61K8/606 , A61K8/498 , A61K8/63 , A61K8/671 , A61K8/675 , A61Q19/00 , A61Q19/08 , Y10S514/844 , Y10S514/846 , Y10S514/847 , Y10S514/848
摘要： The present invention relates to compositions for preventing or treating skin disorders using vitamin B3 compounds and polycyclic compounds. The present invention also relates to methods for regulating skin condition.
摘要翻译： 本发明涉及使用维生素B3化合物和多环化合物预防或治疗皮肤病症的组合物。 本发明还涉及调节皮肤状况的方法。
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6.发明授权
公开(公告)号：US4847069A
公开(公告)日：1989-07-11
申请号：US112588
申请日：1987-10-22
IPC分类号： A61K8/00 , A61K8/31 , A61K8/33 , A61K8/34 , A61K8/35 , A61K8/36 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/39 , A61K8/40 , A61K8/41 , A61K8/42 , A61K8/44 , A61K8/49 , A61K8/67 , A61K8/86 , A61K8/89 , A61K8/891 , A61K8/92 , A61K8/97 , A61K8/98 , A61Q1/00 , A61Q1/04 , A61Q1/06 , A61Q1/12 , A61Q5/02 , A61Q17/04 , A61Q19/08 , C11D3/48
CPC分类号： A61Q17/04 , A61K8/44 , A61K8/445 , A61K8/498 , A61K8/678 , A61Q1/02 , A61Q1/06 , A61Q19/00 , A61Q19/10 , A61Q5/02 , Y10S514/846 , Y10S514/847 , Y10S514/873 , Y10S514/937 , Y10S514/944
摘要： Disclosed are pharmaceutical compositions comprising sorbohydroxamic acid, or pharmaceutically-acceptable salts thereof, and an anti-inflammatory agent, which are useful for topical application to prevent damage to skin caused by acute or chronic UV exposure. Combinations of sorbohydroxamic acid and an anti-inflammatory agent together with tocopherol sorbate and/or sunscreens are also disclosed.Also disclosed is a method for using these compositions topically to prevent damage to skin caused by acute or chronic UV exposure.
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公开(公告)号：US06492326B1
公开(公告)日：2002-12-10
申请号：US09544789
申请日：2000-04-07
IPC分类号： A61K3800
CPC分类号： A61Q19/00 , A61K8/29 , A61K8/34 , A61K8/342 , A61K8/368 , A61K8/37 , A61K8/40 , A61K8/42 , A61K8/466 , A61K8/4926 , A61K8/64 , A61K8/675 , A61Q19/08
摘要： The present invention relates to skin care compositions containing combinations of skin care actives and to methods of using such compositions to regulate the condition of skin. The compositions contain a safe and effective amount of amount of a peptide active selected from the group consisting of pentapeptides, derivatives of pentapeptides, and mixtures thereof; a safe and effective amount of at least one additional skin care active; and a dermatologically acceptable carrier.
摘要翻译： 本发明涉及含有皮肤护理活性物质的组合的护肤组合物以及使用这些组合物调节皮肤状况的方法。 组合物含有安全有效量的肽活性物质，其选自五肽，五肽衍生物及其混合物; 安全有效量的至少一种额外的护肤活性物质; 和皮肤病学上可接受的载体。
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公开(公告)号：US6093411A
公开(公告)日：2000-07-25
申请号：US267874
申请日：1999-03-12
申请人： Donald Lynn Bissett
发明人： Donald Lynn Bissett
IPC分类号： A61K8/00 , A61K8/29 , A61K8/30 , A61K8/34 , A61K8/35 , A61K8/36 , A61K8/368 , A61K8/37 , A61K8/40 , A61K8/42 , A61K8/43 , A61K8/49 , A61K8/60 , A61K8/97 , A61K31/12 , A61K31/352 , A61K31/37 , A61K45/06 , A61Q19/00 , A61Q19/08 , A61K7/00
CPC分类号： A61K8/498 , A61K31/12 , A61K31/352 , A61K31/37 , A61K45/06 , A61K8/35 , A61K8/602 , A61K8/97 , A61Q17/04 , A61Q19/00 , A61Q19/02 , A61Q19/08 , Y10S514/859
摘要： The present invention relates to compositions for preventing or treating skin disorders using flavonoid compounds. The present invention also relates to methods for regulating skin condition.
摘要翻译： 本发明涉及使用类黄酮化合物预防或治疗皮肤病症的组合物。 本发明还涉及调节皮肤状况的方法。
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9.发明授权Compositions comprising a radical scavenging compound and an anti-inflammatory agent 失效包含自由基清除化合物和抗炎剂的组合物
公开(公告)号：US5709847A
公开(公告)日：1998-01-20
申请号：US744891
申请日：1996-11-08
IPC分类号： A61K8/44 , A61K8/49 , A61K8/67 , A61K9/10 , A61Q5/02 , A61Q17/04 , A61Q19/00 , A61Q19/10 , A61K7/42 , A61K7/00
CPC分类号： A61Q17/04 , A61K8/44 , A61K8/445 , A61K8/498 , A61K8/678 , A61Q19/00 , A61Q19/10 , A61Q5/02 , Y10S424/05 , Y10S514/844 , Y10S514/846 , Y10S514/847 , Y10S514/873 , Y10S514/937 , Y10S514/938 , Y10S514/944 , Y10S514/945
摘要： Disclosed are pharmaceutical compositions comprising a radical scavenging agent and an anti-inflammatory agent which are useful for topical application to prevent damage to skin caused by acute or chronic UV exposure. Combinations of a radical scavenging agent, an anti-inflammatory agent, and a sunscreen are also disclosed. Also disclosed is a method for using these compositions topically to prevent damage to skin caused by acute or chronic UV exposure.
摘要翻译： 公开了包含自由基清除剂和抗炎剂的药物组合物，其可用于局部施用以防止由急性或慢性UV暴露引起的对皮肤的损伤。 还公开了自由基清除剂，抗炎剂和防晒剂的组合。 还公开了一种局部使用这些组合物以防止由急性或慢性紫外线暴露引起的皮肤损伤的方法。
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10.发明申请REGULATION OF MAMMALIAN KERATINOUS TISSUE USING HEXAMIDINE COMPOSITIONS 审中-公开使用HEXAMIDINE组合物调理马马里兰KERATINOUS组织公开(公告)号：US20100278765A1
公开(公告)日：2010-11-04
申请号：US12835244
申请日：2010-07-13
申请人： Donald Lynn Bissett
发明人： Donald Lynn Bissett
IPC分类号： A61K8/67 , A61K31/455 , A61K31/7008 , A61K38/02 , A61K38/05 , A61K31/56 , A61K31/522 , A61Q1/00 , A61Q17/04 , A61Q19/04 , A61Q19/00 , A61Q19/06 , A61P29/00 , A61P17/10 , A61P17/18 , A61P31/04 , A61P31/10 , A61P17/00
CPC分类号： A61K8/40 , A61K8/347 , A61K8/43 , A61K8/606 , A61K8/671 , A61K8/675 , A61Q19/00 , A61Q19/007 , A61Q19/02 , A61Q19/06 , A61Q19/08
摘要： The present invention relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods each comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of a skin care composition comprising: a) a safe and effective amount of a hexamidine compound selected from the group consisting of hexamidine, its salts, and derivatives; b) a safe and effective amount of one or more skin care active selected from the group consisting of sugar amine, vitamin B3, retinoid, peptide, phytosterol, butylated hydroxytoluene and butylated hydroxyanisole, their derivatives, and combinations thereof; and c) a dermatologically acceptable carrier for the hexamidine and the skin care active. In additional embodiments, the above composition is suitable for preventing, retarding, and/or treating dark under-eye circles, puffy eyes, sagging, sallowness as well as spider vessels and/or red blotchiness of skin, promoting skin desquamation, exfoliation, and/or turnover, regulating and/or reducing pore size appearance, preventing/retarding tanning, regulating oily/shiny appearance, preventing, retarding, and/or treating hyperpigmentation in mammalian skin, preventing, retarding, and/or treating itchiness of mammalian skin, preventing, retarding, and/or treating dryness of skin, preventing, retarding, and/or treating fine lines and wrinkles, preventing, retarding, and/or treating skin atrophy of mammalian skin, softening and/or smoothing lips, hair and nails of a mammal, and preventing, retarding, and/or treating the appearance of cellulite in mammalian skin.
摘要翻译： 本发明涉及用于调节哺乳动物角质组织状况的方法，其中各方法包括局部施用于需要这种治疗的哺乳动物的角质组织的步骤，安全有效量的皮肤护理组合物，其包含：a） 安全有效量的选自己脒，其盐和衍生物的己脒化合物; b）安全有效量的一种或多种选自糖胺，维生素B3，类视色素，肽，植物甾醇，丁基化羟基甲苯和丁基化羟基苯甲醚，其衍生物及其组合的护肤活性物质; 和c）用于己脒和皮肤护理活性的皮肤病学可接受的载体。 在另外的实施方案中，上述组合物适合于预防，延缓和/或治疗黑眼圈，浮肿眼睛，下垂，黄斑以及蜘蛛血管和/或皮肤红斑，促进皮肤脱屑，剥脱和 /或周转，调节和/或减少毛孔外观，防止/阻滞鞣制，调节油性/光泽外观，预防，延缓和/或治疗哺乳动物皮肤色素沉着过度，预防，延缓和/或治疗哺乳动物皮肤的瘙痒， 防止，延缓和/或治疗皮肤干燥，预防，延缓和/或治疗细纹和皱纹，预防，延缓和/或治疗哺乳动物皮肤的萎缩，软化和/或平滑唇，头发和指甲 哺乳动物，并且预防，延缓和/或治疗哺乳动物皮肤中脂肪团的外观。
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