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    Dermal substance collection device
    5.
    发明授权
    Dermal substance collection device 失效
    真皮物质收集装置

    公开(公告)号：US4960467A

    公开(公告)日：1990-10-02

    申请号：US283347

    申请日：1988-12-12

    申请人： Carl C. Peck

    发明人： Carl C. Peck

    IPC分类号： A61B10/00 ,  G01N33/48

    CPC分类号： G01N33/48 ,  A61B10/0064 ,  A61B2010/0009

    摘要： A dermal substance collection device (DSCD) is described which provides ms for the non-invasive, instantaneous and continuous monitoring of chemical substances which are present in a detectable amount in either or both interstitial fluid or sweat or which are on or in the skin. The transdermal substance collection device of this invention is comprised of three essential components: (1) a substance binding reservoir, wettable by (2) a liquid transfer medium which allows for liquid bridge transfer of a soluble substance from the skin surface to the binding reservoir by virtue of its wettability by the liquid, and (3) an occlusive cover.

    摘要翻译： 描述了一种真皮物质收集装置（DSCD），其提供用于非侵入性，瞬时和连续监测化学物质的手段，所述化学物质以组合液或汗液中的一种或两种或皮肤上或皮肤中的可检测量存在。 本发明的透皮物质收集装置由三个基本组成部分组成：（1）物质结合储存器，可通过（2）液体转移介质润湿，该液体转移介质允许将可溶性物质从皮肤表面液相转移到结合储存器 由于其通过液体的润湿性，和（3）封闭盖。

    Dermal substance collection method
    6.
    发明授权
    Dermal substance collection method 失效
    真皮物质收集方​​法

    公开(公告)号：US4819645A

    公开(公告)日：1989-04-11

    申请号：US116763

    申请日：1987-11-04

    申请人： Carl C. Peck

    发明人： Carl C. Peck

    IPC分类号： G01N33/50 ,  A61B5/00 ,  A61B10/00 ,  A61F13/00 ,  G01N1/10 ,  G01N33/48 ,  G01N33/483

    CPC分类号： G01N33/48 ,  A61B10/0064 ,  A61B5/4283 ,  A61B2010/0009

    摘要： A dermal substance collection device (DSCD) is described which provides ms for the non-invasive, instantaneous and continuous monitoring of chemical substances which are present in a detectable amount in either or both interstitial fluid or sweat or which are on or in the skin. The transdermal substance collection device of this invention is comprised of three essential components: (1) a substance binding reservoir, wettable by (2) a liquid transfer medium which allows for liquid bridge transfer of a soluble substance from the skin surface to the binding reservoir by virtue of its wettability by the liquid, and (3) an occlusive cover.

    摘要翻译： 描述了一种真皮物质收集装置（DSCD），其提供用于非侵入性，瞬时和连续监测化学物质的手段，所述化学物质以组合液或汗液中的一种或两种或皮肤上或皮肤中的可检测量存在。 本发明的透皮物质收集装置由三个基本组成部分组成：（1）物质结合储存器，可通过（2）液体转移介质润湿，该液体转移介质允许将可溶性物质从皮肤表面液相转移到结合储存器 由于其通过液体的润湿性，和（3）封闭盖。

    Dermal substance collection device
    7.
    发明授权
    Dermal substance collection device 失效

    公开(公告)号：US4706676A

    公开(公告)日：1987-11-17

    申请号：US660778

    申请日：1985-02-11

    申请人： Carl C. Peck

    发明人： Carl C. Peck

    IPC分类号： G01N33/50 ,  A61B5/00 ,  A61B10/00 ,  A61F13/00 ,  G01N1/10 ,  G01N33/48 ,  G01N33/483

    CPC分类号： G01N33/48 ,  A61B10/0064 ,  A61B5/4283 ,  A61B2010/0009

    摘要： A dermal substance collection device (DSCD) is described which provides means for the non-invasive, instantaneous and continuous monitoring of chemical substances which are present in a detectable amount in either or both interstitial fluid or sweat or which are on or in the skin. The transdermal substance collection device of this invention is comprised of three essential components: (1) a substance binding reservoir, wettable by (2) a liquid transfer medium which allows for liquid bridge transfer of a soluble substance from the skin surface to the binding reservoir by virtue of its wettability by the liquid, and (3) an occlusive cover.

    Transdermal detection system
    8.
    发明授权
    Transdermal detection system 失效
    透皮检测系统

    公开(公告)号：US4821733A

    公开(公告)日：1989-04-18

    申请号：US87699

    申请日：1987-08-18

    申请人： Carl C. Peck

    发明人： Carl C. Peck

    IPC分类号： A61B10/00 ,  A61B5/00 ,  C12Q1/28 ,  C12Q1/54 ,  G01N33/50 ,  G01N33/53 ,  G01N33/98

    CPC分类号： A61B5/14521 ,  A61B5/14532 ,  C12Q1/28 ,  C12Q1/54 ,  G01N33/50 ,  G01N33/5302 ,  C12Q2326/12

    摘要： A transdermal detection system for the detection of a target substance which migrates to the surface of the skin of a subject by diffusion comprises detector means and attachment means. The detector means includes at least one detector chemical contained in solution and capable of chemically reacting with the target substance as the target substance migrates to the skin surface of the subject to produce a detectable signal, and a barrier means for substantially preventing migration of the detector chemical into the skin surface of the subject. The attachment means maintains the detector means adjacent the surface of the skin of the subject.

    Transdermal vapor collection method and apparatus
    9.
    发明授权
    Transdermal vapor collection method and apparatus 失效
    透皮蒸气收集方法和装置

    公开(公告)号：US4909256A

    公开(公告)日：1990-03-20

    申请号：US121306

    申请日：1987-11-16

    申请人： Carl C. Peck

    发明人： Carl C. Peck

    IPC分类号： G01N33/50 ,  A61B5/00 ,  A61B10/00 ,  A61B10/02 ,  A61F13/00 ,  G01N1/10 ,  G01N33/48 ,  G01N33/483

    CPC分类号： A61B10/0064 ,  A61B5/4283 ,  G01N33/48 ,  A61B2010/0009

    摘要： A method for the non-invasive, continuous collection of substances which transdermally migrate to and vaporize at the surface of the skin of a subject comprises providing a binding reservoir material juxtaposed at the surface of the skin of a subject, and continuously maintaining the binding reservoir material in a substantially airtight relation with the skin surface over an entire collection period. The apparatus comprises a binding reservoir material and means for continuously maintaining the binding reservoir material juxtaposed at the skin surface of the subject in a substantially airtight relation wiht the skin surface.

    摘要翻译： 在受试者的皮肤表面经皮迁移和蒸发的物质的非侵入式连续收集的方法包括提供并列在受试者皮肤表面的结合储存器材料，并且连续地保持结合储存器 材料在整个收集期间与皮肤表面基本上气密的关系。 该装置包括结合储存器材料和用于连续地保持结合储存器材料的装置，该结合储存器材料以与皮肤表面基本上气密的关系并置在受试者的皮肤表面上。