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1.发明申请Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42 有权编码新型睾丸特异性微管蛋白酪氨酸连接酶样蛋白的多核苷酸BGS42公开(公告)号：US20080026401A1
公开(公告)日：2008-01-31
申请号：US11900344
申请日：2007-09-10
申请人： John Feder , Shujian Wu , Thomas Nelson , Liana Lee
发明人： John Feder , Shujian Wu , Thomas Nelson , Liana Lee
CPC分类号： C12N9/93 , A01K2217/05 , A01K2217/075 , A61K38/00 , C07K2319/00 , G01N33/57423 , G01N2333/9015 , Y10S435/81
摘要： The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供了编码BGS-42多肽的新型多核苷酸，其片段和同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型BGS-42多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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2.发明申请Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunoglobulin folds, BGS2, 3 and 4 and variants thereof 失效编码具有富含亮氨酸重复序列和免疫球蛋白折叠的三种新型人细胞表面蛋白的多核苷酸，BGS2,3和4及其变体公开(公告)号：US20070178088A1
公开(公告)日：2007-08-02
申请号：US11726220
申请日：2007-03-21
申请人： Shujian Wu , Stanley Krystek , Liana Lee , John Feder , Janet Cheng
发明人： Shujian Wu , Stanley Krystek , Liana Lee , John Feder , Janet Cheng
IPC分类号： A61K39/395 , G01N33/53 , C07H21/04 , C12P21/06 , C07K14/705 , C07K16/28 , A61K38/17
CPC分类号： C07K14/705 , A61K38/00
摘要： The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供了编码BGS-2,3和4多肽，其片段和同系物的新型多核苷酸。还提供了用于产生所述多肽的载体，宿主细胞，抗体以及重组和合成方法。 本发明还涉及将这些新型BGS-2,3和4多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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3.发明申请Polynucleotide encoding a novel TRP channel family member, TRP-PLIK2, and splice variants thereof 有权编码新型TRP通道家族成员的多核苷酸，TRP-PLIK2及其剪接变体公开(公告)号：US20070172880A1
公开(公告)日：2007-07-26
申请号：US11726234
申请日：2007-03-21
申请人： Ning Lee , Jian Chen , John Feder , Shujian Wu , Han Chang , Liana Lee , Michael Blanar , David Bol
发明人： Ning Lee , Jian Chen , John Feder , Shujian Wu , Han Chang , Liana Lee , Michael Blanar , David Bol
CPC分类号： C07K14/705
摘要： The present invention provides novel polynucleotides encoding TRP-PLIK2 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of TRP-PLIK2 polypeptides, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel TRP-PLIK2, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供了编码TRP-PLIK2多肽的新型多核苷酸，其片段和同源物。 本发明还提供分别编码TRP-PLIK2多肽，TRP-PLIK2b，TRP-PLIK2c和TRP-PLIK2d的变体和剪接变体的多核苷酸。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型TRP-PLIK2，TRP-PLIK2b，TRP-PLIK2c和TRP-PLIK2d多肽应用于诊断，治疗和/或预防与这些相关的各种疾病和/或病症的诊断和治疗方法 多肽。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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4.发明申请公开(公告)号：US20070071743A1
公开(公告)日：2007-03-29
申请号：US11601407
申请日：2006-11-17
申请人： Liana Lee , John Feder , Shujian Wu , Jian Chen
发明人： Liana Lee , John Feder , Shujian Wu , Jian Chen
IPC分类号： A61K39/395 , C07H21/04 , C12P21/06 , C12N5/06 , C07K14/705 , C07K16/42
CPC分类号： C07K14/705 , A61K38/00 , C07K14/70503
摘要： The present invention provides novel polynucleotides encoding BGS-19 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying the novel BGS-19 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供了编码BGS-19多肽的新型多核苷酸，其片段和同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将新型BGS-19多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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公开(公告)号：US20060105379A1
公开(公告)日：2006-05-18
申请号：US11313356
申请日：2005-12-21
申请人： Shujian Wu , Jian Chen , John Feder , Liana Lee , Stanley Krystek
发明人： Shujian Wu , Jian Chen , John Feder , Liana Lee , Stanley Krystek
CPC分类号： C12N9/6489
摘要： The present invention provides novel polynucleotides encoding MMP-29 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MMP-29 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
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6.发明申请Polynucleotides encoding a novel human Kupffer cell receptor protein, BGS-18 审中-公开编码新型人类枯否细胞受体蛋白BGS-18的多核苷酸公开(公告)号：US20060003367A1
公开(公告)日：2006-01-05
申请号：US11152697
申请日：2005-06-14
申请人： Shujian Wu , John Feder , Thomas Nelson
发明人： Shujian Wu , John Feder , Thomas Nelson
IPC分类号： C12Q1/68 , C07H21/04 , C12P21/06 , C07K14/705
CPC分类号： C07K14/705
摘要： The present invention provides novel polynucleotides encoding BGS-18 polypeptide, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-18 polypeptide to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供编码BGS-18多肽的新型多核苷酸，其片段及其同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型BGS-18多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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7.发明申请公开(公告)号：US20060269544A1
公开(公告)日：2006-11-30
申请号：US11496357
申请日：2006-07-31
申请人： John Feder , Shujian Wu , Thomas Nelson
发明人： John Feder , Shujian Wu , Thomas Nelson
IPC分类号： A61K39/395 , C07H21/04 , C12N9/00 , C12P21/06
CPC分类号： C12N9/93 , A01K2217/05 , A01K2217/075 , A61K38/00 , C07K2319/00 , G01N33/57423 , G01N2333/9015 , Y10S435/81
摘要： The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
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8.发明申请Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42 有权编码新型睾丸特异性微管蛋白酪氨酸连接酶样蛋白的多核苷酸BGS42公开(公告)号：US20060246051A1
公开(公告)日：2006-11-02
申请号：US11445988
申请日：2006-06-02
申请人： John Feder , Shujian Wu , Thomas Nelson
发明人： John Feder , Shujian Wu , Thomas Nelson
IPC分类号： C12Q1/68 , G01N33/567 , C07H21/04 , C12P21/06 , A61K38/48 , C12N9/64 , G01N33/53 , C07K16/40
CPC分类号： C12N9/93 , A01K2217/05 , A01K2217/075 , A61K38/00 , C07K2319/00 , G01N33/57423 , G01N2333/9015 , Y10S435/81
摘要： The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供了编码BGS-42多肽的新型多核苷酸，其片段和同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型BGS-42多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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9.发明授权Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof 失效编码具有富含亮氨酸重复序列和免疫球蛋白折叠的三种新型人细胞表面蛋白的多核苷酸，BGS2,3和4及其变体公开(公告)号：US07223558B2
公开(公告)日：2007-05-29
申请号：US10193477
申请日：2002-07-11
申请人： Shujian Wu , Stanley R. Krystek , Liana Lee , John N. Feder , Janet D. Cheng
发明人： Shujian Wu , Stanley R. Krystek , Liana Lee , John N. Feder , Janet D. Cheng
CPC分类号： C07K14/705 , A61K38/00
摘要： The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供了编码BGS-2,3和4多肽的新型多核苷酸，其片段及其同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型BGS-2,3和4多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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公开(公告)号：US20090088385A1
公开(公告)日：2009-04-02
申请号：US12283245
申请日：2008-09-10
申请人： Shujian Wu , Stanley R. Krystek , Liana Lee , John N. Feder , Janet D. Cheng
发明人： Shujian Wu , Stanley R. Krystek , Liana Lee , John N. Feder , Janet D. Cheng
CPC分类号： C07K14/705 , A61K38/00
摘要： The present invention provides novel polynucleotides encoding BGS-4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing the polypeptides of the present invention. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.
摘要翻译： 本发明提供了编码BGS-4多肽的新型多核苷酸，其片段和同源物。 还提供载体，宿主细胞，抗体，以及用于产生本发明多肽的重组和合成方法。 本发明还涉及将这些新型BGS-4多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。
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