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13 条记录 (耗时 0.083 秒)

    Polynucleotide encoding a novel TRP channel family member, TRP-PLIK2, and splice variants thereof
    1.
    发明申请
    Polynucleotide encoding a novel TRP channel family member, TRP-PLIK2, and splice variants thereof 有权
    编码新型TRP通道家族成员的多核苷酸，TRP-PLIK2及其剪接变体

    公开(公告)号：US20070172880A1

    公开(公告)日：2007-07-26

    申请号：US11726234

    申请日：2007-03-21

    申请人： Ning Lee ,  Jian Chen ,  John Feder ,  Shujian Wu ,  Han Chang ,  Liana Lee ,  Michael Blanar ,  David Bol

    发明人： Ning Lee ,  Jian Chen ,  John Feder ,  Shujian Wu ,  Han Chang ,  Liana Lee ,  Michael Blanar ,  David Bol

    IPC分类号： C12Q1/68 ,  G01N33/53 ,  A61K38/17 ,  C07K14/705 ,  C07K16/28 ,  C07H21/04 ,  C12P21/06

    CPC分类号： C07K14/705

    摘要： The present invention provides novel polynucleotides encoding TRP-PLIK2 polypeptides, fragments and homologues thereof. The present invention also provides polynucleotides encoding variants and splice variants of TRP-PLIK2 polypeptides, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d, respectively. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel TRP-PLIK2, TRP-PLIK2b, TRP-PLIK2c, and TRP-PLIK2d polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码TRP-PLIK2多肽的新型多核苷酸，其片段和同源物。 本发明还提供分别编码TRP-PLIK2多肽，TRP-PLIK2b，TRP-PLIK2c和TRP-PLIK2d的变体和剪接变体的多核苷酸。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型TRP-PLIK2，TRP-PLIK2b，TRP-PLIK2c和TRP-PLIK2d多肽应用于诊断，治疗和/或预防与这些相关的各种疾病和/或病症的诊断和治疗方法 多肽。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Novel human cell surface protein with immunoglobulin folds, BGS-19
    2.
    发明申请
    Novel human cell surface protein with immunoglobulin folds, BGS-19 审中-公开
    具有免疫球蛋白折叠的新型人细胞表面蛋白BGS-19

    公开(公告)号：US20070071743A1

    公开(公告)日：2007-03-29

    申请号：US11601407

    申请日：2006-11-17

    申请人： Liana Lee ,  John Feder ,  Shujian Wu ,  Jian Chen

    发明人： Liana Lee ,  John Feder ,  Shujian Wu ,  Jian Chen

    IPC分类号： A61K39/395 ,  C07H21/04 ,  C12P21/06 ,  C12N5/06 ,  C07K14/705 ,  C07K16/42

    CPC分类号： C07K14/705 ,  A61K38/00 ,  C07K14/70503

    摘要： The present invention provides novel polynucleotides encoding BGS-19 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying the novel BGS-19 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-19多肽的新型多核苷酸，其片段和同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将新型BGS-19多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42
    5.
    发明申请
    Polynucleotides encoding a novel testis-specific tubulin tyrosine-ligase-like protein, BGS42 有权
    编码新型睾丸特异性微管蛋白酪氨酸连接酶样蛋白的多核苷酸BGS42

    公开(公告)号：US20080026401A1

    公开(公告)日：2008-01-31

    申请号：US11900344

    申请日：2007-09-10

    申请人： John Feder ,  Shujian Wu ,  Thomas Nelson ,  Liana Lee

    发明人： John Feder ,  Shujian Wu ,  Thomas Nelson ,  Liana Lee

    IPC分类号： C12Q1/68 ,  C12Q1/00 ,  G01N33/53

    CPC分类号： C12N9/93 ,  A01K2217/05 ,  A01K2217/075 ,  A61K38/00 ,  C07K2319/00 ,  G01N33/57423 ,  G01N2333/9015 ,  Y10S435/81

    摘要： The present invention provides novel polynucleotides encoding BGS-42 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-42 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-42多肽的新型多核苷酸，其片段和同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型BGS-42多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Metalloprotease highly expressed in the testis, MMP-29
    6.
    发明授权
    Metalloprotease highly expressed in the testis, MMP-29 有权
    金属蛋白酶在睾丸中高度表达，MMP-29

    公开(公告)号：US07285633B2

    公开(公告)日：2007-10-23

    申请号：US11313356

    申请日：2005-12-21

    申请人： Shujian Wu ,  Jian Chen ,  John N. Feder ,  Liana Lee ,  Stanley R. Krystek

    发明人： Shujian Wu ,  Jian Chen ,  John N. Feder ,  Liana Lee ,  Stanley R. Krystek

    IPC分类号： A61K38/17

    CPC分类号： C12N9/6489

    摘要： The present invention provides novel polynucleotides encoding MMP-29 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel MMP-29 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码MMP-29多肽的新型多核苷酸，其片段和同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型MMP-29多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof
    7.
    发明授权
    Polynucleotides encoding three novel human cell surface proteins with leucine rich repeats and immunologobulin folds, BGS2, 3, and 4 and variants thereof 失效
    编码具有富含亮氨酸重复序列和免疫球蛋白折叠的三种新型人细胞表面蛋白的多核苷酸，BGS2,3和4及其变体

    公开(公告)号：US07223558B2

    公开(公告)日：2007-05-29

    申请号：US10193477

    申请日：2002-07-11

    申请人： Shujian Wu ,  Stanley R. Krystek ,  Liana Lee ,  John N. Feder ,  Janet D. Cheng

    发明人： Shujian Wu ,  Stanley R. Krystek ,  Liana Lee ,  John N. Feder ,  Janet D. Cheng

    IPC分类号： C12N15/12 ,  C12N5/10 ,  C12P21/02 ,  C07K14/47

    CPC分类号： C07K14/705 ,  A61K38/00

    摘要： The present invention provides novel polynucleotides encoding BGS-2, 3, and 4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing said polypeptides. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-2, 3, and 4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-2,3和4多肽的新型多核苷酸，其片段及其同源物。 还提供了载体，宿主细胞，抗体以及用于产生所述多肽的重组和合成方法。 本发明还涉及将这些新型BGS-2,3和4多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。

    Antibodies that bind to BGS-4
    8.
    发明申请
    Antibodies that bind to BGS-4 失效
    与BGS-4结合的抗体

    公开(公告)号：US20090088385A1

    公开(公告)日：2009-04-02

    申请号：US12283245

    申请日：2008-09-10

    申请人： Shujian Wu ,  Stanley R. Krystek ,  Liana Lee ,  John N. Feder ,  Janet D. Cheng

    发明人： Shujian Wu ,  Stanley R. Krystek ,  Liana Lee ,  John N. Feder ,  Janet D. Cheng

    IPC分类号： A61K38/16 ,  C07K16/00 ,  G01N33/68 ,  A61P37/00 ,  A61P29/00 ,  A61P35/00 ,  A61P9/00

    CPC分类号： C07K14/705 ,  A61K38/00

    摘要： The present invention provides novel polynucleotides encoding BGS-4 polypeptides, fragments and homologues thereof. Also provided are vectors, host cells, antibodies, and recombinant and synthetic methods for producing the polypeptides of the present invention. The invention further relates to diagnostic and therapeutic methods for applying these novel BGS-4 polypeptides to the diagnosis, treatment, and/or prevention of various diseases and/or disorders related to these polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention.

    摘要翻译： 本发明提供了编码BGS-4多肽的新型多核苷酸，其片段和同源物。 还提供载体，宿主细胞，抗体，以及用于产生本发明多肽的重组和合成方法。 本发明还涉及将这些新型BGS-4多肽应用于诊断，治疗和/或预防与这些多肽相关的各种疾病和/或病症的诊断和治疗方法。 本发明还涉及用于鉴定本发明的多核苷酸和多肽的激动剂和拮抗剂的筛选方法。