公开(公告)号：US20080090226A1

公开(公告)日：2008-04-17

申请号：US11954356

申请日：2007-12-12

申请人： John Hackett ,  Julie Yamaguchi ,  Alan Golden ,  Catherine Brennan ,  Robert Hickman ,  Shushil Devare

发明人： John Hackett ,  Julie Yamaguchi ,  Alan Golden ,  Catherine Brennan ,  Robert Hickman ,  Shushil Devare

IPC分类号： C07H21/04 ,  C07K16/00 ,  C12N15/00 ,  C12N5/02 ,  C12Q1/70

CPC分类号： C07K14/005 ,  A61K39/00 ,  C07K2319/00 ,  C12N2740/16122 ,  G01N2333/162

摘要： Isolated HIV-1 Group O env polypeptides obtained from the HIV-1 isolate HAM112 are claimed, as well as (a) antigen constructs comprising fusions of one or more of each of HIV-1 Group O env polypeptides and HIV-1 Group M env polypeptide and (b) further antigen constructs containing additional Group O sequences and especially the gp41 IDR of isolate HAM112. Also claimed are polynucleotide sequences encoding the above, expression vectors comprising the same, host cells transformed thereby, and immunoassay methods and kits utilizing the antigen constructs of the invention.

公开(公告)号：US20080090994A1

公开(公告)日：2008-04-17

申请号：US11954351

申请日：2007-12-12

申请人： John Hackett ,  Julie Yamaguchi ,  Alan Golden ,  Catherine Brennan ,  Robert Hickman ,  Sushil Devare

发明人： John Hackett ,  Julie Yamaguchi ,  Alan Golden ,  Catherine Brennan ,  Robert Hickman ,  Sushil Devare

IPC分类号： C07K16/00

CPC分类号： C07K14/005 ,  A61K39/00 ,  C07K2319/00 ,  C12N2740/16122 ,  G01N2333/162

摘要： Isolated HIV-1 Group O env polypeptides obtained from the HIV-1 isolate HAM112 are claimed, as well as (a) antigen constructs comprising fusions of one or more of each of HIV-1 Group O env polypeptides and HIV-1 Group M env polypeptide and (b) further antigen constructs containing additional Group O sequences and especially the gp41 IDR of isolate HAM112. Also claimed are polynucleotide sequences encoding the above, expression vectors comprising the same, host cells transformed thereby, and immunoassay methods and kits utilizing the antigen constructs of the invention.

摘要翻译： 要求保护从HIV-1分离株HAM112获得的分离的HIV-1组O env多肽，以及（a）包含HIV-1组O型多肽和HIV-1组M env中的一种或多种的融合物的抗原构建体 多肽和（b）另外的含有其他组O序列的抗原构建物，特别是分离株HAM112的gp41 IDR。 还要求保护的是编码上述的多核苷酸序列，包含其的表达载体，由此转化的宿主细胞，以及利用本发明的抗原构建体的免疫测定方法和试剂盒。

公开(公告)号：US20060153866A1

公开(公告)日：2006-07-13

申请号：US11008351

申请日：2004-12-09

申请人： John Hackett ,  Julie Yamaguchi ,  Alan Golden ,  Catherine Brennan ,  Robert Hickman ,  Sushil Devare

发明人： John Hackett ,  Julie Yamaguchi ,  Alan Golden ,  Catherine Brennan ,  Robert Hickman ,  Sushil Devare

IPC分类号： A61K39/21 ,  C07K14/16

CPC分类号： C07K14/005 ,  A61K39/00 ,  C07K2319/00 ,  C12N2740/16122 ,  G01N2333/162

摘要： Isolated HIV-1 Group O env polypeptides obtained from the HIV-1 isolate HAM112 are claimed, as well as (a) antigen constructs comprising fusions of one or more of each of HIV-1 Group O env polypeptides and HIV-1 Group M env polypeptide and (b) further antigen constructs containing additional Group O sequences and especially the gp41 IDR of isolate HAM112. Also claimed are polynucleotide sequences encoding the above, expression vectors comprising the same, host cells transformed thereby, and immunoassay methods and kits utilizing the antigen constructs of the invention.

公开(公告)号：US20060043678A1

公开(公告)日：2006-03-02

申请号：US10926567

申请日：2004-08-26

申请人： Alan Golden

发明人： Alan Golden

IPC分类号： A63F9/04 ,  A63F3/08

CPC分类号： A63F3/00157 ,  A63F9/04

摘要： A casino craps table layout is provided with unique wagering opportunities. There are specific wagering areas for placing a wager on at least one of two new wagering opportunities. These new wagering opportunities are selected from the group consisting of a) a wager that the next roll of the dice will be a hard 4, 6, 8 or 10 and b) a wager that the next roll of the dice will be a pair of numbers. Another new wagering opportunity is a placed wager for any specific number (e.g., 4, 5, 6, 8, 9, and 10).