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1.发明申请Cholesterol-Interacting Layered Phyllosilicates and Methods of Reducing Hypercholesteremia in a Mammal 审中-公开胆固醇相互作用层状叶绿酸盐和减少哺乳动物血胆固醇血症的方法公开(公告)号：US20070281025A1
公开(公告)日：2007-12-06
申请号：US11752460
申请日：2007-05-23
IPC分类号： A61K33/00 , A61K31/19 , A61K31/27 , A61K31/35 , A61K31/405 , A61K31/435 , A61K47/00 , A61P9/00 , A61K9/00 , A61K38/00 , A61K31/44 , A61K31/47 , A61K31/505 , A61K31/70
CPC分类号： A61K33/00 , A61K31/19 , A61K31/27 , A61K31/35 , A61K31/405 , A61K31/435 , A61K31/44 , A61K31/47 , A61K31/505 , A61K31/70 , A61K45/06 , A61K2300/00
摘要： Layered phyllosilicates are useful for adsorbing and/or binding to cholesterol and, thereby, reducing blood cholesterol in a patient. Accordingly, provided herein is a method of reducing hypercholesteremia in a mammal comprising administering to said mammal a layered phyllosilicate material alone and in combination with other cholesterol-reducing agents in an amount effective to reduce hypercholesteremia in said mammal.
摘要翻译： 层状页硅酸盐可用于吸附和/或结合胆固醇，从而降低患者的血液胆固醇。 因此，本文提供的是减少哺乳动物的高胆固醇血症的方法，包括向所述哺乳动物单独施用层状页硅酸盐物质，并与其它降胆固醇剂组合施用有效降低所述哺乳动物血清胆固醇血症的量。
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2.发明申请Virus-interacting layered phyllosilicates and methods of inactivating viruses in the gastrointestinal tract 审中-公开病毒相互作用的层状页硅酸盐和灭活胃肠道病毒的方法公开(公告)号：US20070231412A1
公开(公告)日：2007-10-04
申请号：US11641639
申请日：2006-12-18
CPC分类号： C09C1/42 , A01N59/00 , A01N59/06 , C01P2004/20 , C01P2004/61
摘要： Layered phyllosilicates are useful for adsorbing and/or binding to and, thereby, inactivating viruses. Accordingly, provided herein is a method of inactivating a virus in the gastrointestinal tract of a mammalian subject comprising administering to said subject a composition comprising a layered phyllosilicate material in an amount effective for virus inactivation. Also provided are methods of treating a viral infection in the gastrointestinal tract of a mammalian subject. Methods of delivering a therapeutic agent to a mammalian subject and methods of inactivating a virus in waste expelled from a mammal are also provided.
摘要翻译： 层状页硅酸盐可用于吸附和/或结合病毒，从而使病毒失活。 因此，本文提供的是灭活哺乳动物受试者的胃肠道中的病毒的方法，包括向所述受试者施用含有有效用于病毒灭活的量的层状页硅酸盐材料的组合物。 还提供了治疗哺乳动物受试者的胃肠道中的病毒感染的方法。 还提供了向哺乳动物受试者递送治疗剂的方法和从哺乳动物排出的废物中灭活病毒的方法。
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3.发明申请Virus-interacting layered phyllosilicates and methods of inactivating viruses on animate and inanimate surfaces 审中-公开病毒相互作用的层状页硅酸盐和在动画和无生命表面上灭活病毒的方法公开(公告)号：US20070224293A1
公开(公告)日：2007-09-27
申请号：US11641319
申请日：2006-12-18
CPC分类号： C09C1/42 , A01N59/00 , A01N59/06 , C01P2004/20 , C01P2004/61
摘要： Layered phyllosilicates are useful for adsorbing and/or binding to and, thereby, inactivating viruses. Accordingly, provided herein is a method of inhibiting transfer of a virus to a surface comprising contacting the surface with a composition comprising a layered phyllosilicate material in an amount sufficient for inhibiting the transfer of the virus thereto. Also provided are methods of inactivating a virus on a surface comprising contacting the surface with a composition comprising a layered phyllosilicate material in an amount sufficient to inactivate said virus.
摘要翻译： 层状页硅酸盐可用于吸附和/或结合病毒，从而灭活病毒。 因此，本文提供了一种抑制病毒转移到表面的方法，包括使表面与包含层状页硅酸盐材料的组合物接触，所述组合物的量足以抑制病毒转移到其上。 还提供了使表面灭活病毒的方法，包括使表面与含有足以灭活所述病毒的量的层状页硅酸盐材料的组合物接触。
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公开(公告)号：US20070059542A1
公开(公告)日：2007-03-15
申请号：US11599080
申请日：2006-11-14
CPC分类号： B32B3/26 , B01D39/1623 , B01D2239/0659 , B01D2239/0668 , B01D2239/0681 , B01D2239/10 , B09C1/002 , B09C1/08 , B32B3/02 , B32B5/26 , B32B7/12 , B32B37/12 , B32B2262/0253 , B32B2264/10 , B32B2307/726 , D04H3/00 , D06N3/0011 , D06N2201/02 , D06N2201/0254 , D06N2201/0263 , D06N2205/10 , D06N2209/126 , D06N2211/16 , E02D17/202 , E02D31/004 , Y10T156/1069 , Y10T428/24 , Y10T428/249921 , Y10T428/31786 , Y10T442/659 , Y10T442/674 , Y10T442/676 , Y10T442/699
摘要： Reactive geocomposite mats, and their method of manufacture, for treating contaminants in soil or water that allow the passage of essentially non-contaminated water therethrough. The geocomposite mat includes a pre-formed woven or non-woven geotextile, having a thickness of about 6 mm to about 200 mm, and having, a porosity sufficient to receive a powdered or granular contaminant-reactive material, contaminant-sorptive material, or a contaminant-neutralizing material (hereinafter collectively referred to as “contaminant-reactant material” or “contaminant-reactive material”) throughout its thickness, or in any portion of the thickness across its entire major surface(s). The powdered or granular contaminant-reactive material is disposed within the pores of the previously formed, high loft geotextile mat to surround the fibers, e.g., by vacuum or vibrating the high loft mat while in contact with the contaminant-reactive material to allow the powdered or granular contaminant-reactive material to flow by gravity into the pores of the previously formed geotextile and vibrational forces. Liquid-permeable cover sheets are adhered to the upper and lower major surfaces of the filled geotextile to prevent the powdered or granular material from escaping from the geotextile during transportation and installation.
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5.发明申请公开(公告)号：US20070206994A1
公开(公告)日：2007-09-06
申请号：US11741376
申请日：2007-04-27
IPC分类号： B09C1/00
CPC分类号： E02D17/20 , B32B5/06 , B32B5/26 , B32B5/30 , B32B27/12 , B32B27/32 , B32B2262/0253 , B32B2262/0261 , B32B2262/0276 , B32B2262/062 , B32B2262/065 , B32B2262/067 , B32B2264/0214 , B32B2264/104 , B32B2264/108 , B32B2307/726 , E02D17/202
摘要： Reactive geocomposite mats, and their method of manufacture, for treating contaminants in sediment, soil or water that allow the passage of essentially non-contaminated water therethrough. The geocomposite mat includes a pre-formed woven or non-woven geotextile, that is needlepunched to an outer geotextile sheet layer to provide a high loft, structurally secured, pre-formed geotextile having a thickness of about 6 mm to about 200 mm, and having, a porosity sufficient to receive a powdered or granular contaminant-reactive material, contaminant-sorptive material, or a contaminant-neutralizing material (hereinafter collectively referred to as “contaminant-reactant material” or “contaminant-reactive material”) throughout its thickness, or in any portion of the thickness across its entire major surface(s). The powdered or granular contaminant-reactive material is disposed within the pores of the previously formed, high loft geotextile mat to surround the fibers, e.g., by vacuum or vibrating the high loft mat while in contact with the contaminant-reactive material to allow the powdered or granular contaminant-reactive material to flow by gravity into the pores of the previously formed, needlepunched geotextile. A liquid-permeable outer geotextile sheet then is secured to the filled geotextile, preferably by heating upwardly extending fibers of the pre-formed geotextile mat to prevent the powdered or granular material from escaping from the geotextile during transportation and installation.
摘要翻译： 反应性地质复合材料垫及其制造方法，用于处理允许基本上未经污染的水通过的沉积物，土壤或水中的污染物。 地层复合垫包括预先形成的机织或非织造土工织物，其被针刺到外部土工织物层，以提供具有约6mm至约200mm厚度的高隆起，结构上固定的预成型土工织物，以及 具有足以容纳粉末或颗粒污染物反应性材料，污染物吸收性材料或污染物中和材料（以下统称为“污染物 - 反应物材料”或“污染物反应性材料”）的孔隙，其整个厚度 ，或在其整个主表面上的厚度的任何部分。 粉末或颗粒状污染物反应性材料设置在先前形成的高隆起土工织物垫的孔内，以围绕纤维，例如通过真空或振动高隆顶垫，同时与污染物反应性材料接触以允许粉末状 或颗粒状污染物反应性材料通过重力流入先前形成的针刺土工织物的孔中。 然后将液体可渗透的外部土工织物片材固定到填充的土工织物上，优选地通过加热预先形成的土工织物垫的向上延伸的纤维来防止粉末状或颗粒状材料在运输和安装期间从土工织物中逸出。
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6.发明申请Contaminant-reactive geocomposite mat and method of manufacture and use 审中-公开污染物反应性地质复合材料垫及其制造和使用方法公开(公告)号：US20050103707A1
公开(公告)日：2005-05-19
申请号：US10718128
申请日：2003-11-19
CPC分类号： B32B3/26 , B01D39/1623 , B01D2239/0659 , B01D2239/0668 , B01D2239/0681 , B01D2239/10 , B09C1/002 , B09C1/08 , B32B3/02 , B32B5/26 , B32B7/12 , B32B37/12 , B32B2262/0253 , B32B2264/10 , B32B2307/726 , D04H3/00 , D06N3/0011 , D06N2201/02 , D06N2201/0254 , D06N2201/0263 , D06N2205/10 , D06N2209/126 , D06N2211/16 , E02D17/202 , E02D31/004 , Y10T156/1069 , Y10T428/24 , Y10T428/249921 , Y10T428/31786 , Y10T442/659 , Y10T442/674 , Y10T442/676 , Y10T442/699
摘要： Reactive geocomposite mats, and their method of manufacture, for treating contaminants in soil or water that allow the passage of essentially non-contaminated water therethrough. The geocomposite mat includes a pre-formed woven or non-woven geotextile, having a thickness of about 6 mm to about 200 mm, and having, a porosity sufficient to receive a powdered or granular contaminant-reactive material, contaminant-sorptive material, or a contaminant-neutralizing material (hereinafter collectively referred to as “contaminant-reactant material” or “contaminant-reactive material”) throughout its thickness, or in any portion of the thickness across its entire major surface(s). The powdered or granular contaminant-reactive material is disposed within the pores of the previously formed, high loft geotextile mat to surround the fibers, e.g., by vacuum or vibrating the high loft mat while in contact with the contaminant-reactive material to allow the powdered or granular contaminant-reactive material to flow by gravity into the pores of the previously formed geotextile and vibrational forces. Liquid-permeable cover sheets are adhered to the upper and lower major surfaces of the filled geotextile to prevent the powdered or granular material from escaping from the geotextile during transportation and installation.
摘要翻译： 反应性地质复合材料垫及其制造方法，用于处理土壤或水中的污染物，使基本上未经污染的水通过其中。 地层复合垫包括预成型的织造或非织造土工织物，其厚度为约6mm至约200mm，并且具有足以容纳粉末或颗粒状污染物反应性材料的孔隙率，污染物吸收性材料或 污染物中和材料（以下统称为“污染物 - 反应物材料”或“污染物反应性材料”），其整个厚度或其整个主表面的厚度的任何部分。 粉末或颗粒状污染物反应性材料设置在先前形成的高隆起土工织物垫的孔内，以围绕纤维，例如通过真空或振动高隆顶垫，同时与污染物反应性材料接触以允许粉末状 或颗粒状污染物反应性材料通过重力流入先前形成的土工织物的孔隙和振动力。 透液性覆盖片粘附到填充土工织物的上下表面，以防止粉状或颗粒状材料在运输和安装过程中从土工织物中逸出。
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7.发明申请公开(公告)号：US20050065262A1
公开(公告)日：2005-03-24
申请号：US10666315
申请日：2003-09-18
申请人： Jerald Darlington , Natalie Dotlich
发明人： Jerald Darlington , Natalie Dotlich
CPC分类号： C08L23/10 , C08K3/346 , C08K9/02 , C08L23/20 , C08L23/22 , Y10T428/31667 , C08L2666/06
摘要： A water-swelling composition adapted to be secured to an area of potential water flow in the form of a flexible cohesive mass comprising about 10% to about 90% by weight of a water-swellable layered material; about 1% to about 30% by weight of an elastomer; about 8% to about 65% by weight of a material selected from the group consisting of polypropene, polybutene, and a mixture thereof; and about 0.1% to about 20% by weight of a clay binder selected from group consisting of (1) an onium ion-liberating compound that is ion-exchanged with platelet cations of the layered material, (2) a coupling agent that is reacted with the layered material, and (3) a combination thereof.
摘要翻译： 一种水溶胀组合物，其适于固定到柔性粘性物质形式的潜在水流区域，其包含约10重量％至约90重量％的水溶胀性层状材料; 约1％至约30％重量的弹性体; 约8重量％至约65重量％的选自聚丙烯，聚丁烯及其混合物的材料; 和约0.1重量％至约20重量％的粘土粘合剂，其选自（1）与层状材料的血小板阳离子离子交换的鎓离子释放化合物，（2）反应的偶联剂 与层状材料，（3）其组合。
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8.发明申请Contaminant-reactive geocomposite mat and method of manufacture and use 审中-公开污染物反应性地质复合材料垫及其制造和使用方法公开(公告)号：US20070227981A1
公开(公告)日：2007-10-04
申请号：US11807463
申请日：2007-05-29
CPC分类号： B32B3/26 , B01D39/1623 , B01D2239/0659 , B01D2239/0668 , B01D2239/0681 , B01D2239/10 , B09C1/002 , B09C1/08 , B32B3/02 , B32B5/26 , B32B7/12 , B32B37/12 , B32B2262/0253 , B32B2264/10 , B32B2307/726 , D04H3/00 , D06N3/0011 , D06N2201/02 , D06N2201/0254 , D06N2201/0263 , D06N2205/10 , D06N2209/126 , D06N2211/16 , E02D17/202 , E02D31/004 , Y10T156/1069 , Y10T428/24 , Y10T428/249921 , Y10T428/31786 , Y10T442/659 , Y10T442/674 , Y10T442/676 , Y10T442/699
摘要： Reactive geocomposite mats, and their method of manufacture, for treating contaminants in soil or water that allow the passage of essentially non-contaminated water therethrough. The geocomposite mat includes a pre-formed woven or non-woven geotextile, having a thickness of about 6 mm to about 200 mm, and having, a porosity sufficient to receive a powdered or granular contaminant-reactive material, contaminant-sorptive material, or a contaminant-neutralizing material (hereinafter collectively referred to as “contaminant-reactant material” or “contaminant-reactive material”) throughout its thickness, or in any portion of the thickness across its entire major surface(s). The powdered or granular contaminant-reactive material is disposed within the pores of the previously formed, high loft geotextile mat to surround the fibers, e.g., by vacuum or vibrating the high loft mat while in contact with the contaminant-reactive material to allow the powdered or granular contaminant-reactive material to flow by gravity into the pores of the previously formed geotextile and vibrational forces. Liquid-permeable cover sheets are adhered to the upper and lower major surfaces of the filled geotextile to prevent the powdered or granular material from escaping from the geotextile during transportation and installation.
摘要翻译： 反应性地质复合材料垫及其制造方法，用于处理土壤或水中的污染物，使基本上未经污染的水通过其中。 地层复合垫包括预成型的织造或非织造土工织物，其厚度为约6mm至约200mm，并且具有足以容纳粉末或颗粒状污染物反应性材料的孔隙率，污染物吸收性材料或 污染物中和材料（以下统称为“污染物 - 反应物材料”或“污染物反应性材料”），其整个厚度或其整个主表面的厚度的任何部分。 粉末或颗粒状污染物反应性材料设置在先前形成的高隆起土工织物垫的孔内，以围绕纤维，例如通过真空或振动高隆顶垫，同时与污染物反应性材料接触以允许粉末状 或颗粒状污染物反应性材料通过重力流入先前形成的土工织物的孔隙和振动力。 透液性覆盖片粘附到填充土工织物的上下表面，以防止粉状或颗粒状材料在运输和安装过程中从土工织物中逸出。
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公开(公告)号：US20070169709A1
公开(公告)日：2007-07-26
申请号：US11339107
申请日：2006-01-25
申请人： Zhen Wang , Vincent Losacco , Mick Velder , Bala Nathan , Bart Becherer , Jerald Darlington
发明人： Zhen Wang , Vincent Losacco , Mick Velder , Bala Nathan , Bart Becherer , Jerald Darlington
IPC分类号： A01K29/00
CPC分类号： A01K1/01 , A01K1/0152 , A01K1/0154 , A01K1/0155 , A47L13/41 , B03C1/0332 , B03C1/28 , B03C1/30 , B03C2201/20
摘要： A particulate clumping animal litter composition is disclosed. The composition comprises water-swellable smectite clay particles bound to magnetically-attractable metal particles such that substantially all particles of the animal litter composition are attracted to a magnetic surface. The animal litter composition exhibits favorable properties such as absorbency, resiliency, homogeneity, clump strength, and particle size. Methods of production for clumping animal litter compositions are also disclosed that employ sufficient shear to bind the water-swellable smectite clay particles to the magnetically-attractable metal particles such that the animal litter compositions exhibit favorable properties. A method and apparatus for the collection of magnetically-attractable animal litter particles are also disclosed.
摘要翻译： 公开了一种颗粒状聚集的动物垃圾组合物。 该组合物包含与可吸引金属颗粒结合的水溶胀性蒙脱石粘土颗粒，使得基本上所有的动物垃圾组合物的颗粒被吸引到磁性表面。 动物垫料组合物表现出吸收性，弹性，均匀性，团块强度和粒度等有利的性质。 还公开了用于结块动物垫料组合物的生产方法，其采用足够的剪切力将水溶胀性蒙脱石粘土颗粒结合到磁吸引金属颗粒上，使得动物垫料组合物显示出有利的性质。 还公开了一种用于收集可磁吸引的动物垃圾颗粒的方法和装置。
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10.发明申请Nonviscous aqueous dispersion compositions of water-swellable layered silicates and the method of producing the same 审中-公开水溶胀性层状硅酸盐的非粘性水性分散体组合物及其制造方法公开(公告)号：US20070151931A1
公开(公告)日：2007-07-05
申请号：US11710765
申请日：2007-02-26
申请人： Ashoke SenGupta , Jerald Darlington , Jennifer Gould , Ilona Lin
发明人： Ashoke SenGupta , Jerald Darlington , Jennifer Gould , Ilona Lin
CPC分类号： C08K3/34 , A61K8/26 , A61K8/817 , A61K2800/5426 , A61Q5/06 , C02F1/5236 , C02F1/56 , C02F2103/002 , C08K3/346 , C08K7/00
摘要： Concentrated suspensions of smectite clays are obtained as either relatively “thin” or highly shear-thinning slurries that are easy to pump, by adding one or more of certain cationic polymers whose weight average molecular weight, Mw, is 50,000 or higher. It was found during the course of the invention that a cationic polymer with an Mw of 10,000 did not work, while the same polymer with a bimodal Mw of 50,000 and 30,000 worked satisfactorily. To achieve the full advantage of the present invention, the cationic polymer preferably has 1 to 10 milliequivalents of cationic charge per gram of the polymer, and more preferably 5 to 10 milliequivalents of cationic charge per gram of the polymer, and most preferably 6 to 8 milliequivalents of cationic charge per gram of the polymer.
摘要翻译： 通过加入一种或多种重均分子量Mw为50,000或更高的某些阳离子聚合物，获得蒙脱石粘土的浓缩悬浮液，作为易于泵送的相对“薄”或高剪切稀化浆料。 在本发明的过程中发现，Mw为10,000的阳离子聚合物不起作用，而具有50,000和30,000的双峰Mw的相同聚合物工作令人满意。 为了实现本发明的全部优点，阳离子聚合物优选每克聚合物具有1至10毫当量的阳离子电荷，更优选每克聚合物具有5至10毫当量阳离子电荷，最优选6至8个 每克聚合物的阳离子电荷的毫当量。
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