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公开(公告)号：US07585663B2
公开(公告)日：2009-09-08
申请号：US10926915
申请日：2004-08-26
发明人： John S. Shigeura , Sean M. Desmond , David M. Cox
CPC分类号： G05D23/24 , G05D23/192 , G05D23/20 , G05D23/22 , Y02P20/129 , Y10S435/809
摘要： A device, system, and method are provided for thermally treating a fluid processing device. According to various embodiments, a system is provided that can include a thermal device and a fluid processing device holder. The thermal device can include a first block having a thermal conductivity greater than 0.5 Watt per centimeter Kelvin (W/cm·K), a second block having a thermal conductivity greater than 0.5 W/cm·K, and a heat-pump device disposed between the first block and the second block. The heat-pump device can transfer thermal energy from at least one of the first block and the second block to the other of the first block and the second block. The fluid processing device holder can hold a fluid processing device in a heat-transfer position with respect to the first block and the second block. The fluid processing device can be a microfluidic device.
摘要翻译： 提供了用于热处理流体处理装置的装置，系统和方法。 根据各种实施例，提供一种可以包括热装置和流体处理装置支架的系统。 热装置可以包括具有大于0.5瓦/厘米开尔文（W / cm·K）的热导率的第一块，具有大于0.5W / cm·K的热导率的第二块，以及设置在所述热泵装置 在第一块和第二块之间。 热泵装置可以将热能从第一块和第二块中的至少一个传递到第一块和第二块中的另一个块。 流体处理装置保持器可以将流体处理装置保持在相对于第一块和第二块的热传递位置。 流体处理装置可以是微流体装置。
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公开(公告)号：US20090325277A1
公开(公告)日：2009-12-31
申请号：US12552218
申请日：2009-09-01
IPC分类号： C12M1/34
CPC分类号： G05D23/24 , G05D23/192 , G05D23/20 , G05D23/22 , Y02P20/129 , Y10S435/809
摘要： A device, system, and method are provided for thermally treating a fluid processing device. According to various embodiments, a system is provided that can include a thermal device and a fluid processing device holder. The thermal device can include a first block having a thermal conductivity greater than 0.5 Watt per centimeter Kelvin (W/cm·K), a second block having a thermal conductivity greater than 0.5 W/cm·K, and a heat-pump device disposed between the first block and the second block. The heat-pump device can transfer thermal energy from at least one of the first block and the second block to the other of the first block and the second block. The fluid processing device holder can hold a fluid processing device in a heat-transfer position with respect to the first block and the second block. The fluid processing device can be a microfluidic device.
摘要翻译： 提供了用于热处理流体处理装置的装置，系统和方法。 根据各种实施例，提供一种可以包括热装置和流体处理装置支架的系统。 热装置可以包括具有大于0.5瓦/厘米开尔文（W / cm·K）的热导率的第一块，具有大于0.5W / cm·K的热导率的第二块，以及设置在所述热泵装置 在第一块和第二块之间。 热泵装置可以将热能从第一块和第二块中的至少一个传递到第一块和第二块中的另一个块。 流体处理装置保持器可以将流体处理装置保持在相对于第一块和第二块的热传递位置。 流体处理装置可以是微流体装置。
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公开(公告)号：US20110236964A1
公开(公告)日：2011-09-29
申请号：US13153902
申请日：2011-06-06
IPC分类号： C12M1/34
CPC分类号： G01N27/44721 , B82Y10/00 , B82Y20/00 , G01N2015/149 , G01N2015/1497
摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.
摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。
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公开(公告)号：US20090135421A1
公开(公告)日：2009-05-28
申请号：US12321781
申请日：2009-01-26
IPC分类号： G01N21/00
CPC分类号： G01N27/44721 , B82Y10/00 , B82Y20/00 , G01N2015/149 , G01N2015/1497
摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.
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公开(公告)号：US07978326B2
公开(公告)日：2011-07-12
申请号：US12630683
申请日：2009-12-03
申请人： Mark F. Oldham , Eric S. Nordman , Richard T. Reel , John S. Shigeura , Janice G. Shigeura, legal representative
IPC分类号： G01N21/00
CPC分类号： G01N27/44721 , B82Y10/00 , B82Y20/00 , G01N2015/149 , G01N2015/1497
摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.
摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。
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6.发明授权公开(公告)号：US08388901B2
公开(公告)日：2013-03-05
申请号：US13480113
申请日：2012-05-24
CPC分类号： B01L7/52 , B01J19/0093 , B01J2219/00788 , B01J2219/00822 , B01J2219/00862 , B01J2219/00873 , B01J2219/00934 , B01J2219/00943 , B01J2219/00961 , B01L3/50851 , B01L2200/147 , B01L2300/0803 , B01L2300/1838 , B01L2300/185 , B01L2300/1861 , B01L2300/1872 , B01L2400/0409 , G01N2035/00366 , G01N2035/00415
摘要： An apparatus and methods are provided for heating and sensing the temperature of a chemical reaction chamber without direct physical contact between a heating device and the reaction chamber, or between a temperature sensor and the reaction chamber. A plurality of chemical reaction chambers can simultaneously or sequentially be heated independently and monitored separately.
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7.发明申请公开(公告)号：US20120052564A1
公开(公告)日：2012-03-01
申请号：US13218223
申请日：2011-08-25
CPC分类号： B01L7/52 , B01J19/0093 , B01J2219/00788 , B01J2219/00822 , B01J2219/00862 , B01J2219/00873 , B01J2219/00934 , B01J2219/00943 , B01J2219/00961 , B01L3/50851 , B01L2200/147 , B01L2300/0803 , B01L2300/1838 , B01L2300/185 , B01L2300/1861 , B01L2300/1872 , B01L2400/0409 , G01N2035/00366 , G01N2035/00415
摘要： An apparatus and methods are provided for heating and sensing the temperature of a chemical reaction chamber without direct physical contact between a heating device and the reaction chamber, or between a temperature sensor and the reaction chamber. A plurality of chemical reaction chambers can simultaneously or sequentially be heated independently and monitored separately.
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公开(公告)号：US07636160B2
公开(公告)日：2009-12-22
申请号：US12321781
申请日：2009-01-26
申请人： Mark F. Oldham , Eric S. Nordman , Richard T. Reel , John S. Shigeura , Janice G. Shigeura, legal representative
IPC分类号： G01N21/00
CPC分类号： G01N27/44721 , B82Y10/00 , B82Y20/00 , G01N2015/149 , G01N2015/1497
摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.
摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。
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9.发明申请Non-Contact Radiant Heating and Temperature Sensing Device for a Chemical Reaction Chamber 有权用于化学反应室的非接触辐射加热和温度感测装置公开(公告)号：US20120322140A1
公开(公告)日：2012-12-20
申请号：US13480113
申请日：2012-05-24
CPC分类号： B01L7/52 , B01J19/0093 , B01J2219/00788 , B01J2219/00822 , B01J2219/00862 , B01J2219/00873 , B01J2219/00934 , B01J2219/00943 , B01J2219/00961 , B01L3/50851 , B01L2200/147 , B01L2300/0803 , B01L2300/1838 , B01L2300/185 , B01L2300/1861 , B01L2300/1872 , B01L2400/0409 , G01N2035/00366 , G01N2035/00415
摘要： An apparatus and methods are provided for heating and sensing the temperature of a chemical reaction chamber without direct physical contact between a heating device and the reaction chamber, or between a temperature sensor and the reaction chamber. A plurality of chemical reaction chambers can simultaneously or sequentially be heated independently and monitored separately.
摘要翻译： 提供了一种用于加热和感测化学反应室的温度并且在加热装置与反应室之间或温度传感器与反应室之间没有直接物理接触的装置和方法。 多个化学反应室可以独立地同时或顺序地加热并单独监测。
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公开(公告)号：US20120196296A1
公开(公告)日：2012-08-02
申请号：US13442143
申请日：2012-04-09
IPC分类号： G01N21/64
CPC分类号： G01N27/44721 , B82Y10/00 , B82Y20/00 , G01N2015/149 , G01N2015/1497
摘要： An apparatus for detecting labeled beads is provided. The apparatus can include: one or more irradiation sources disposed for irradiating the one or more detection zones with radiation; at least one detector disposed for collecting charges corresponding to light signals emitted from labeled beads in the one or more detection zones, which have been excited by the radiation; and a system coupled to the at least one detector for effecting time delay integration of the charges by accumulating the charges before reading the charges at the output of the at least one detector.
摘要翻译： 提供了一种用于检测标记珠粒的装置。 该装置可以包括：一个或多个辐射源，被设置用于用辐射照射一个或多个检测区域; 至少一个检测器被设置用于收集对应于已经被辐射激发的一个或多个检测区域中的标记珠子发射的光信号的电荷; 以及耦合到所述至少一个检测器的系统，用于通过在读取至少一个检测器的输出端的电荷之前累积电荷来实现电荷的时间延迟积分。
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