Abstract:
The present invention relates to compounds, and prodrugs thereof, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
Abstract:
The present invention relates to compounds, and prodrugs thereof, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
Abstract:
A method is described for inhibiting mitogen activated protein kinase-activated protein kinase-2 in a subject in need of such inhibition, where the method involves administering to the subject a beta-carboline MK-2 inhibiting compound, or a pharmaceutically acceptable salt thereof.
Abstract:
Disclosed is a shelf with a housing having a hollow interior and a tray having a plurality of surfaces, wherein the tray is in communication with the hollow interior of the housing, a holder is attached to the shelf one or more electrical outlets, which are electrically connected to a power source.
Abstract:
Disclosed is a shelf with a housing having a hollow interior and a tray having a plurality of surfaces, wherein the tray is in communication with the hollow interior of the housing, a holder is attached to the shelf one or more electrical outlets, which are electrically connected to a power source.
Abstract:
The present invention provides novel bridged beta-carboline compounds that are capable of inhibiting mitogen activated protein kinase-activated protein kinase-2 and analogues thereof and pharmaceutical compositions and kits that include these compounds.
Abstract:
In an embodiment, a water recapture system comprises one or more trays having a bottom surface and one or more sidewalls extending upward from the bottom surface, wherein the bottom surface has at least one aperture extending therethrough. A platform configured to engage a top side of the one or more sidewalls, wherein the platform has a first tab and a second tab, wherein the first tab and the second tab extend outwardly from the platform. A coupler extending through the at least one aperture of the bottom surface, wherein one end of the coupler is exterior to the tray, and wherein a hose attached to the one end of the coupler, wherein the bottom surface of the tray is contoured, and wherein the contour of the bottom surface is biased towards the at least one aperture.
Abstract:
The present invention relates to compounds, and prodrugs thereof, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
Abstract:
The present invention relates to compounds, and prodrugs thereof, compositions and methods useful for preventing and treating thrombotic conditions in mammals. The compounds of the present invention, and prodrugs thereof, selectively inhibit certain proteases of the coagulation cascade.
Abstract:
The invention relates to substituted polycyclic aryl and heteroaryl pyrazinone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.