公开(公告)号：US06605077B2

公开(公告)日：2003-08-12

申请号：US09899041

申请日：2001-07-06

申请人： John Whittier ,  Peter K. Kratsch

发明人： John Whittier ,  Peter K. Kratsch

IPC分类号： A61B1700

CPC分类号： A61B10/06 ,  A61B17/29 ,  A61B2017/00477

摘要： An endoscopic instrument having an end effector assembly at a distal end, a flexible member connected to and extending from the end effector assembly and a handle assembly connected to the flexible member. The handle assembly includes a handle member, a nose member and a biasing element. The handle member has an inner bore. The hollow nose member has a shank configured for insertion into the inner bore. The biasing element is located within the inner bore and biases the flexible member relative to the handle member. The handle member may have a keyway or a projection configured for insertion into a keyway, and the nose member may have the other of the keyway or the projection. The flexible member has a retaining element affixed to its proximal end. The flexible member is inserted through the nose member with the retaining element located proximate the proximal end of the nose member and thereby retained between the handle member and the nose member. Relative axial movement between the handle member and the flexible member is minimized.

公开(公告)号：US06273882B1

公开(公告)日：2001-08-14

申请号：US09099423

申请日：1998-06-18

申请人： John Whittier ,  Peter K. Kratsch

发明人： John Whittier ,  Peter K. Kratsch

IPC分类号： A61B1700

CPC分类号： A61B10/06 ,  A61B17/29 ,  A61B2017/00477

摘要： An endoscopic instrument having an end effector assembly at a distal end, a flexible member connected to and extending from the end effector assembly and a handle assembly connected to the flexible member. The handle assembly includes a handle member, a nose member and a biasing element. The handle member has an inner bore. The hollow nose member has a shank configured for insertion into the inner bore. The biasing element is located within the inner bore and biases the flexible member relative to the handle member. The handle member may have a keyway or a projection configured for insertion into a keyway, and the nose member may have the other of the keyway or the projection. The flexible member has a retaining element affixed to its proximal end. The flexible member is inserted through the nose member with the retaining element located proximate the proximal end of the nose member and thereby retained between the handle member and the nose member. Relative axial movement between the handle member and the flexible member is minimized.

摘要翻译： 一种内窥镜器械，其具有在远端的端部执行器组件，连接到端部执行器组件并且从端部执行器组件延伸的柔性构件以及连接到柔性构件的手柄组件。 手柄组件包括手柄构件，鼻构件和偏置元件。 手柄构件具有内孔。 中空的鼻部构件具有构造成用于插入到内孔中的柄。 偏置元件位于内孔内并相对于手柄构件偏置柔性构件。 手柄构件可以具有构造成用于插入键槽的键槽或突起，并且鼻构件可以具有键槽或突起中的另一个。 柔性构件具有固定到其近端的保持元件。 柔性构件通过鼻部构件插入，保持元件位于鼻部构件的近端附近，从而保持在把手构件和鼻部构件之间。 把手构件和柔性构件之间的相对轴向运动最小化。

公开(公告)号：US20090192486A1

公开(公告)日：2009-07-30

申请号：US09985466

申请日：2001-11-02

申请人： John G. Wilmot ,  John Whittier ,  Robert L. Hill ,  Seth P. Cain ,  C. Michael Mesa

发明人： John G. Wilmot ,  John Whittier ,  Robert L. Hill ,  Seth P. Cain ,  C. Michael Mesa

IPC分类号： A61M5/20

CPC分类号： A61M5/2033 ,  A61M5/24 ,  A61M5/286 ,  A61M5/3129 ,  A61M5/3202 ,  A61M5/3286 ,  A61M5/3291 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/2086 ,  A61M2005/3151 ,  A61M2205/192 ,  A61M2205/195

摘要： In one embodiment, an automatic injector comprises a cartridge adapted to contain a charge of medicament, a seal structure disposed toward a forward end of the cartridge, a plunger normally disposed in a generally rearward end of the cartridge and movable through the cartridge toward a generally forward end thereof in response to an actuating procedure. The movable plunger rearwardly confines the medicament within the cartridge. A needle normally disposed in communication with the medicament container provides a passage in which the medicament is released into an individual's flesh in response to an actuating procedure projecting the needle into the flesh of the individual. The cartridge having an increased friction region so as to slow the motion of the plunger when the forward end of the needle travels through the seal in order to eliminate coring.

摘要翻译： 在一个实施例中，自动注射器包括适于容纳药剂的药筒，朝向药筒前端设置的密封结构的药筒，通常设置在药筒的大体上后端并可通过药筒移动的柱塞 其响应于致动过程的前端。 可动柱塞将药剂向后限制在药筒内。 通常设置成与药物容器连通的针提供了一种通道，在该通道中响应于将针投射到个体的肉中的致动程序将药物释放到个体的肉中。 所述筒具有增加的摩擦区域，以便当针的前端穿过密封件时减慢柱塞的运动，以消除取芯。

公开(公告)号：US06190399B1

公开(公告)日：2001-02-20

申请号：US08952010

申请日：1998-02-09

申请人： Matthew A. Palmer ,  Charles R. Slater ,  David Turkel ,  John Whittier

发明人： Matthew A. Palmer ,  Charles R. Slater ,  David Turkel ,  John Whittier

IPC分类号： A61B1742

CPC分类号： A61B10/06 ,  A61B10/02 ,  A61B17/30 ,  A61B17/320016 ,  A61B18/14 ,  A61B2010/0225 ,  A61B2017/00398 ,  A61B2017/00867 ,  A61B2017/2926 ,  A61B2017/2931 ,  A61B2017/2937 ,  A61B2017/2939 ,  A61B2018/1253 ,  A61B2018/146 ,  A61B2090/064 ,  A61F2002/30093 ,  A61F2210/0019 ,  A61M2025/0098 ,  A61M2205/6081

摘要： A jaw assembly for an endoscopic bioptome includes a pair of opposed end effectors having resilient arms formed from a super-elastic metal. The distal ends of the resilient arms terminate in end effector jaw cups which are also preferably formed from super-elastic metal, while the proximal portions of the resilient arms include angled portions which urge the jaw cups away from each other. The jaw cups are brought together into a biting action by a cylinder having a sharp distal edge which moves relative to and over he arms of the end effectors. As the resilient arms are formed from a super-elastic metal, they exhibit very high resiliency and durability even after numerous uses.

摘要翻译： 用于内窥镜活检钳的钳组件包括一对相对的端部执行器，其具有由超弹性金属形成的弹性臂。 弹性臂的远端终止于末端执行器颚杯，其也优选地由超弹性金属形成，而弹性臂的近端部分包括使颚杯彼此远离的倾斜部分。 颚杯通过具有尖端的远端边缘的圆柱体一起咬入动作，所述尖锐的远端边缘相对于末端执行器的手臂移动。 由于弹性臂由超弹性金属形成，即使在许多用途之后它们仍具有非常高的弹性和耐久性。

公开(公告)号：US07569035B1

公开(公告)日：2009-08-04

申请号：US09985466

申请日：2001-11-02

申请人： John G. Wilmot ,  John Whittier ,  Robert L. Hill ,  Seth P. Cain ,  C. Michael Mesa

发明人： John G. Wilmot ,  John Whittier ,  Robert L. Hill ,  Seth P. Cain ,  C. Michael Mesa

IPC分类号： A61M5/00

CPC分类号： A61M5/2033 ,  A61M5/24 ,  A61M5/286 ,  A61M5/3129 ,  A61M5/3202 ,  A61M5/3286 ,  A61M5/3291 ,  A61M2005/2013 ,  A61M2005/206 ,  A61M2005/2073 ,  A61M2005/2086 ,  A61M2005/3151 ,  A61M2205/192 ,  A61M2205/195

摘要： In one embodiment, an automatic injector comprises a cartridge adapted to contain a charge of medicament, a seal structure disposed toward a forward end of the cartridge, a plunger normally disposed in a generally rearward end of the cartridge and movable through the cartridge toward a generally forward end thereof in response to an actuating procedure. The movable plunger rearwardly confines the medicament within the cartridge. A needle normally disposed in communication with the medicament container provides a passage in which the medicament is released into an individual's flesh in response to an actuating procedure projecting the needle into the flesh of the individual. The cartridge having an increased friction region so as to slow the motion of the plunger when the forward end of the needle travels through the seal in order to eliminate coring.

摘要翻译： 在一个实施例中，自动注射器包括适于容纳药剂的药筒，朝向药筒前端设置的密封结构的药筒，通常设置在药筒的大体上后端并可通过药筒移动的柱塞 其响应于致动过程的前端。 可动柱塞将药剂向后限制在药筒内。 通常设置成与药物容器连通的针提供了一种通道，在该通道中响应于将针投射到个体的肉中的致动程序将药物释放到个体的肉中。 所述筒具有增加的摩擦区域，以便当针的前端穿过密封件时减慢柱塞的运动，以消除取芯。

公开(公告)号：US06953445B2

公开(公告)日：2005-10-11

申请号：US09971768

申请日：2001-10-09

申请人： John G. Wilmot ,  Robert L. Hill ,  John Whittier

发明人： John G. Wilmot ,  Robert L. Hill ,  John Whittier

IPC分类号： A61J1/05 ,  A61M5/20 ,  A61M5/28 ,  A61M5/31 ,  A61M5/32 ,  A61M5/34 ,  A61M37/00 ,  A61M5/00

CPC分类号： A61M5/343 ,  A61M5/2033 ,  A61M5/2066 ,  A61M5/286 ,  A61M5/3145 ,  A61M5/34 ,  A61M2005/206 ,  A61M2005/2073

摘要： The present invention is directed to an automatic injection device containing a pre-loaded charge of medicament for automatically self-administering the medicament upon actuation thereof. The automatic injection device includes a housing assembly having an interior chamber, an activation assembly and a needle assembly for dispensing a dissolved medicament to a user. A dry compartment for storing a predetermined dry charge of dry medicament is located within the interior chamber. A wet compartment for storing a predetermined amount of liquid injection solution is also located within the interior chamber. A separation assembly separates the dry compartment from the wet compartment. The separation assembly prevents transfer of the liquid injection solution from the wet compartment to the dry compartment prior to activation of the automatic injection device. One or more medicament support assemblies located within the dry compartment prevent the passage of undissolved medicament from the dry compartment.

摘要翻译： 本发明涉及一种自动注射装置，其包含用于在致动药剂时自动给药的药物的预加载药物。 自动注射装置包括壳体组件，其具有内部腔室，激活组件和用于将溶解的药物分配给使用者的针组件。 用于存储预定的干药物的干燥室的干燥室位于内部室内。 用于存储预定量的液体注射溶液的湿室也位于内部室内。 分离组件将干燥室与湿室隔开。 分离组件防止在启动自动注射装置之前将液体注射溶液从湿室转移到干燥室。 位于干燥室内的一个或多个药物支持组件防止未溶解的药物从干燥室中通过。