Cefuroxime axetil granule and process for the preparation thereof
    4.
    发明申请
    Cefuroxime axetil granule and process for the preparation thereof 审中-公开
    头孢呋辛酯颗粒及其制备方法

    公开(公告)号:US20090175952A1

    公开(公告)日:2009-07-09

    申请号:US10584919

    申请日:2005-01-10

    IPC分类号: A61K31/546 A61K9/16 A61P31/00

    摘要: A cefuroxime axetil granule composition comprising a non-crystalline cefuroxime axetil solid dispersion or a substantially amorphous cefuroxime axetil, sucrose fatty acid ester, methacrylic acid-ethylacrylate copolymer and a disintegrating agent has highly desirable performance characteristics in terms of masking the bitterness of cefuroxime axetil, as well as high bioavailability and stability of cefuroxime axetil, and thus, can be advantageously used for oral administration of cefuroxime axetil.

    摘要翻译: 包含非结晶头孢呋辛酯固体分散体或基本无定形的头孢呋辛酯,蔗糖脂肪酸酯,甲基丙烯酸 - 乙基丙烯酸酯共聚物和崩解剂的头孢呋辛酯颗粒组合物在掩盖头孢呋辛酯的苦味方面具有非常理想的性能特征, 以及头孢呋辛酯的高生物利用度和稳定性,因此可有利地用于头孢呋辛酯的口服给药。

    Controlled Release Complex Formulation For Oral Administration of Medicine For Diabetes and Method For The Preparation Thereof
    5.
    发明申请

    公开(公告)号:US20100003289A1

    公开(公告)日:2010-01-07

    申请号:US11722560

    申请日:2005-12-28

    摘要: A controlled release combination formulation for oral administration comprising a) a controlled release portion containing metformin or a pharmaceutically acceptable salt thereof as an active ingredient, and a combination of a polyethylene oxide and a natural gum as a carrier for controlled release; and b) a rapid-release portion containing a sulfonylurea-based medicine for treating diabetes as an active ingredient coated on the controlled release portion is useful for the treatment of diabetes, for it is capable of maintaining an effective concentration of the medicines in blood at a constant level.

    摘要翻译: 一种用于口服给药的控释组合制剂,其包含a)含有二甲双胍或其药学上可接受的盐作为活性成分的受控释放部分,以及作为受控释放的载体的聚环氧乙烷和天然树胶的组合; 和b)包含用于治疗糖尿病作为包被在控制释放部分上的活性成分的磺酰脲类药物的快速释放部分可用于治疗糖尿病,因为它能够维持血液中药物的有效浓度 一个恒定的水平。

    METHOD FOR PREPARING RAPIDLY DISINTEGRATING FORMULATION FOR ORAL ADMINISTRATION
    6.
    发明申请
    METHOD FOR PREPARING RAPIDLY DISINTEGRATING FORMULATION FOR ORAL ADMINISTRATION 审中-公开
    制备口服药物快速消毒配方的方法

    公开(公告)号:US20120110957A1

    公开(公告)日:2012-05-10

    申请号:US13343879

    申请日:2012-01-05

    IPC分类号: B65B63/08

    摘要: A method and packaging machine for preparing rapidly disintegrating formulations for oral administration are disclosed. The present invention is characterized in that a powdery mixture including a pharmaceutically active ingredient and a sugar or a sugar alcohol powder is filled into a packaging material and, thereafter, the mixture, filled in the packaging material, is heated. The present invention can simply and economically prepare an oral formulation which undergoes rapid disintegration in the oral cavity and provides for high-quality administration to patients.

    摘要翻译: 公开了用于制备用于口服给药的快速崩解制剂的方法和包装机。 本发明的特征在于将包含药物活性成分和糖或糖醇粉末的粉末混合物填充到包装材料中,然后将填充在包装材料中的混合物加热。 本发明可以简单且经济地制备在口腔中快速崩解并提供给患者高质量给药的口服制剂。