摘要:
Implantable medical devices with biocompatible coatings and processes for their production are described. The present invention relates in particular to medical implantable devices coated with a carbon-containing layer which devices are produced by at least partially coating the device with a polymer film and heating the polymer film in an atmosphere which is essentially free from oxygen to temperatures in the region of 200° C. to 2500° C., a carbon-containing layer being produced on the implantable medical device.
摘要:
The invention relates to a method of producing medical implants having functionalized surfaces by providing a medical implant with at least one carbon-based layer on at least one part of the surface of the implant, activating the carbon-based layer by creating porosity and functionalizing the activated carbon-based layer. This invention also relates to functionalized implants obtained in by this method.
摘要:
The present invention relates to a method for coating substrates with a carbon-based material, comprising the steps of at least partially coating a substrate with a polymer film on at least one outside surface of the substrate and carbonizing the polymer film in an atmosphere that is essentially free of oxygen at temperatures in the range of 200° C. to 2500° C.
摘要:
The invention relates to a cell cultivation method, which may comprise the steps of preparing a carbon-based substrate with a layered structure, composed of at least two porous material layers, substantially superimposed and joined to each other, a gap which can be flowed through being formed between said layers, or of at least one porous material layer which is arranged or folded on itself, maintaining the shape thereof, such that a gap which can be flowed through is formed between at least two superimposed sections of the material layer. Said method then may comprise loading the substrate with a living and/or propagating biological material and contacting the loaded substrate with a liquid medium.
摘要:
The present invention relates to the use of porous carbon-based bodies for the support and/or immobilization of catalytically active units. Catalytically active units for chemical and/or biological reactions may be essentially immobilized on such supporting bodies. The catalyst units can comprise catalytically active units and porous carbon-based supporting bodies. The present invention further relates to reactors comprising these catalyst units and their use in chemical and biological reactions.
摘要:
The invention relates to a method for the preparation of porous carbon-based material comprising the steps provision of a polymer film provided in the form of a sheet or a coating; as well as pyrolysis and/or carbonization of the polymer film in an atmosphere that is essentially free of oxygen at temperatures in the range of 80° C. to 3,500° C. The invention further relates to carbon-based material producible according to the method mentioned above.
摘要:
The present invention relates to methods for producing carbon-based molded bodies. In particular, the present invention relates to methods for producing porous carbon-based molded bodies by carbonizing organic polymer materials mixed with non-polymeric fillers and subsequently dissolving the fillers out from the carbonized molded bodies. The present invention further relates to methods for producing porous carbon-based molded bodies by carbonizing organic polymer materials mixed with non-polymeric fillers which are substantially completely decomposed during the carbonization. The present invention also relates to a method for producing porous carbon-based molded bodies by carbonizing organic polymer materials, the carbon-based molded bodies being partially oxidized following carbonization so as to produce pores. In addition, the present invention relates to porous molded bodies produced according to one of said methods and the use thereof, especially as cell culture carriers and/or culture systems.
摘要:
A high-frequency spray device is provided that is suitable for applying a coating fluid onto a substrate. The spray device can include an atomizing arrangement, a movable substrate holder, a gas supply, and one or more temperature control elements. The atomizing arrangement can include a resonance body which may have a trumpet-like shape and which can be excited to produce high-frequency vibrations that may provide a spray mist jet of the coating fluid. The spray device can further include a field arrangement capable of generating an electric and/or magnetic field in the region containing the substrate which may influence the deposition of the spray mist jet on the substrate. The spray device may also include a suction arrangement that can affect the shape of the spray jet mist and/or withdraw a portion of the spray jet mist.
摘要:
The present invention relates to a method and a device for applying a defined amount of a coating material onto the surface of an implant by means of a printing process, in particular using a printing roller. The invention also relates to the use of a printing process, in particular a printing roller, for applying a defined amount of a coating material onto the surface of the implant to be coated and to correspondingly produce coated implants.
摘要:
An exemplary embodiment of a reversibly closable bag suitable for the cultivation of cells and/or tissues can be provided. The exemplary bag can comprise at least one reversibly closable aperture in the bag wall, and a surface-increasing convection arrangement inside the bag. The convection arrangement is capable to generate and/or modify a convection in a fluid within said bag when at least one of the fluid, the bag, and the convection arrangement is agitated. For example, the surface increasing convection arrangement can be at least one blade, at least one particulate filler and/or at least one surface-increasing substrate being made of a single mould. A system can also be provided comprising at least two bags, whereas the bags may be interconnected via at least one aperture in their bag wall, and a cultivation process using such a bag or system, in which at least one type of cells, tissue, tissue-like cell cultures, organs, organ-like cell cultures, or multicellular organisms are cultivated in the presence of at least one fluid or solid medium provided for growing and/or cultivating the aforesaid culture.