公开(公告)号：US20080118649A1

公开(公告)日：2008-05-22

申请号：US11962091

申请日：2007-12-21

申请人： Jorg Rathenow ,  Jurgen Kunstmann ,  Bernhard Mayer ,  Andreas Ban ,  Soheil Asgari

发明人： Jorg Rathenow ,  Jurgen Kunstmann ,  Bernhard Mayer ,  Andreas Ban ,  Soheil Asgari

IPC分类号： B05D3/00

CPC分类号： A61L27/34 ,  A61L27/303 ,  A61L31/084 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/606 ,  Y10T428/30

摘要： The present invention relates to a method for coating substrates with a carbon-based material, comprising the steps of at least partially coating a substrate with a polymer film on at least one outside surface of the substrate and carbonizing the polymer film in an atmosphere that is essentially free of oxygen at temperatures in the range of 200° C. to 2500° C.

摘要翻译： 本发明涉及一种用碳基材料涂覆基材的方法，包括以下步骤：在基材的至少一个外表面上用聚合物膜至少部分地涂覆基材，并在聚合物膜的气氛中碳化 在200℃至2500℃的温度范围内基本上不含氧。

公开(公告)号：US20050079200A1

公开(公告)日：2005-04-14

申请号：US10938995

申请日：2004-09-10

申请人： Jorg Rathenow ,  Andreas Ban ,  Jurgen Kunstmann ,  Bernhard Mayer ,  Soheil Asgari

发明人： Jorg Rathenow ,  Andreas Ban ,  Jurgen Kunstmann ,  Bernhard Mayer ,  Soheil Asgari

IPC分类号： A61L27/30 ,  A61L31/08 ,  A61L31/10 ,  A61L31/16 ,  A61F2/02 ,  A61F2/06 ,  A61F2/24 ,  A61F2/28 ,  B05D3/00

CPC分类号： A61L27/303 ,  A61L31/084 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/608

摘要： Implantable medical devices with biocompatible coatings and processes for their production are described. The present invention relates in particular to medical implantable devices coated with a carbon-containing layer which devices are produced by at least partially coating the device with a polymer film and heating the polymer film in an atmosphere which is essentially free from oxygen to temperatures in the region of 200° C. to 2500° C., a carbon-containing layer being produced on the implantable medical device.

摘要翻译： 描述了具有生物兼容性涂层的植入式医疗装置及其生产方法。 本发明特别涉及涂覆有含碳层的医用可植入装置，该装置通过至少部分地用聚合物膜涂覆该装置并在基本上不含氧气的气氛中加热该聚合物薄膜而产生， 200℃至2500℃的区域，在可植入医疗装置上制造含碳层。

公开(公告)号：US20050079201A1

公开(公告)日：2005-04-14

申请号：US10939021

申请日：2004-09-10

申请人： Jorg Rathenow ,  Soheil Asgari ,  Andreas Ban ,  Jurgen Kunstmann ,  Bernhard Mayer

发明人： Jorg Rathenow ,  Soheil Asgari ,  Andreas Ban ,  Jurgen Kunstmann ,  Bernhard Mayer

IPC分类号： A61F2/02 ,  A61L27/30 ,  A61L27/50 ,  A61L27/56 ,  A61L31/00 ,  A61L31/08 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  B05D3/04 ,  B05D3/10

CPC分类号： A61L27/56 ,  A61L27/30 ,  A61L27/303 ,  A61L31/082 ,  A61L31/084 ,  A61L31/10 ,  A61L31/146 ,  A61L31/16 ,  A61L2300/00 ,  A61L2400/18

摘要： The invention relates to a method of producing medical implants having functionalized surfaces by providing a medical implant with at least one carbon-based layer on at least one part of the surface of the implant, activating the carbon-based layer by creating porosity and functionalizing the activated carbon-based layer. This invention also relates to functionalized implants obtained in by this method.

摘要翻译： 本发明涉及通过在植入物表面的至少一部分上提供具有至少一个碳基层的医用植入物来生产具有功能化表面的医用植入物的方法，通过产生孔隙并使功能化的 活性炭基层。 本发明还涉及通过该方法获得的功能化植入物。

公开(公告)号：US20060160200A1

公开(公告)日：2006-07-20

申请号：US11343479

申请日：2006-01-30

申请人： Jorg Rathenow ,  Jurgen Kunstmann ,  Andreas Ban ,  Soheil Asgari

发明人： Jorg Rathenow ,  Jurgen Kunstmann ,  Andreas Ban ,  Soheil Asgari

IPC分类号： C12N11/02 ,  C12M1/14

CPC分类号： B01D71/021 ,  B01D53/228 ,  B01D53/885 ,  B01D63/06 ,  B01D63/061 ,  B01D63/081 ,  B01D63/082 ,  B01D63/10 ,  B01D63/14 ,  B01D67/0072 ,  B01D69/00 ,  B01D69/145 ,  B01D2313/08 ,  B01D2315/06 ,  B01D2325/08 ,  B01D2325/24 ,  B01J35/065 ,  B82Y30/00 ,  C12M23/20 ,  C12M25/06 ,  C12M25/14 ,  C12M27/12 ,  C12N5/0068 ,  C12N2533/10

摘要： The present invention relates to the use of porous carbon-based bodies for the support and/or immobilization of catalytically active units. Catalytically active units for chemical and/or biological reactions may be essentially immobilized on such supporting bodies. The catalyst units can comprise catalytically active units and porous carbon-based supporting bodies. The present invention further relates to reactors comprising these catalyst units and their use in chemical and biological reactions.

摘要翻译： 本发明涉及多孔碳基体用于催化活性单元的载体和/或固定化的用途。 用于化学和/或生物反应的催化活性单元可以基本上固定在这种支撑体上。 催化剂单元可以包含催化活性单元和多孔碳基支撑体。 本发明还涉及包含这些催化剂单元的反应器及其在化学和生物反应中的用途。

公开(公告)号：US20060172417A1

公开(公告)日：2006-08-03

申请号：US11343307

申请日：2006-01-31

申请人： Jorg Rathenow ,  Jurgen Kunstmann ,  Andreas Ban ,  Soheil Asgari

发明人： Jorg Rathenow ,  Jurgen Kunstmann ,  Andreas Ban ,  Soheil Asgari

IPC分类号： C12N5/00

CPC分类号： B01D71/021 ,  B01D53/228 ,  B01D53/885 ,  B01D63/06 ,  B01D63/061 ,  B01D63/081 ,  B01D63/082 ,  B01D63/10 ,  B01D63/14 ,  B01D67/0072 ,  B01D69/00 ,  B01D69/145 ,  B01D2313/08 ,  B01D2315/06 ,  B01D2325/08 ,  B01D2325/24 ,  B01J35/065 ,  B82Y30/00 ,  C12M23/20 ,  C12M25/06 ,  C12M25/14 ,  C12M27/12 ,  C12N5/0068 ,  C12N2533/10

摘要： The invention relates to a cell cultivation method, which may comprise the steps of preparing a carbon-based substrate with a layered structure, composed of at least two porous material layers, substantially superimposed and joined to each other, a gap which can be flowed through being formed between said layers, or of at least one porous material layer which is arranged or folded on itself, maintaining the shape thereof, such that a gap which can be flowed through is formed between at least two superimposed sections of the material layer. Said method then may comprise loading the substrate with a living and/or propagating biological material and contacting the loaded substrate with a liquid medium.

摘要翻译： 本发明涉及一种细胞培养方法，其可以包括以下步骤：制备具有层叠结构的碳基基底，所述层状结构由至少两个多孔材料层组成，基本上彼此重叠和连接，可以流过的间隙 形成在所述层之间，或至少一个多孔材料层，其被布置或折叠在其自身上，保持其形状，从而在材料层的至少两个重叠部分之间形成可流过的间隙。 所述方法然后可以包括用活的和/或传播的生物材料装载衬底，并使负载的衬底与液体介质接触。

公开(公告)号：US07371425B2

公开(公告)日：2008-05-13

申请号：US10939022

申请日：2004-09-10

申请人： Jorg Rathenow ,  Jurgen Kunstmann ,  Bernhard Mayer ,  Andreas Ban

发明人： Jorg Rathenow ,  Jurgen Kunstmann ,  Bernhard Mayer ,  Andreas Ban

IPC分类号： B05D3/04

CPC分类号： A61L27/34 ,  A61L27/303 ,  A61L31/084 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/606 ,  Y10T428/30

摘要： The present invention relates to a method for coating substrates with a carbon-based material, comprising the steps of at least partially coating a substrate with a polymer film on at least one outside surface of the substrate and carbonizing the polymer film in an atmosphere that is essentially free of oxygen at temperatures in the range of 200° C. to 2500° C.

公开(公告)号：US20050079356A1

公开(公告)日：2005-04-14

申请号：US10939022

申请日：2004-09-10

申请人： Jorg Rathenow ,  Jurgen Kunstmann ,  Bernhard Mayer ,  Andreas Ban

发明人： Jorg Rathenow ,  Jurgen Kunstmann ,  Bernhard Mayer ,  Andreas Ban

IPC分类号： A61L27/30 ,  A61L27/34 ,  A61L31/08 ,  A61L31/10 ,  A61L31/16 ,  C23C16/26 ,  B32B9/00

CPC分类号： A61L27/34 ,  A61L27/303 ,  A61L31/084 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/606 ,  Y10T428/30

摘要： The present invention relates to a method for coating substrates with a carbon-based material, comprising the steps of at least partially coating a substrate with a polymer film on at least one outside surface of the substrate and carbonizing the polymer film in an atmosphere that is essentially free of oxygen at temperatures in the range of 200° C. to 2500° C.

摘要翻译： 本发明涉及一种用碳基材料涂覆基材的方法，包括以下步骤：在基材的至少一个外表面上用聚合物膜至少部分地涂覆基材，并在聚合物膜的气氛中碳化 在200℃至2500℃的温度范围内基本上不含氧。

公开(公告)号：US20060159718A1

公开(公告)日：2006-07-20

申请号：US11343480

申请日：2006-01-30

申请人： Jorg Rathenow ,  Soheil Asgari ,  Jurgen Kunstmann

发明人： Jorg Rathenow ,  Soheil Asgari ,  Jurgen Kunstmann

IPC分类号： A61F2/28 ,  C01B31/00 ,  A61F13/00

CPC分类号： B01D67/0088 ,  A61L27/08 ,  A61L27/38 ,  A61L27/56 ,  B01D67/0072 ,  B01D69/04 ,  B01D71/021 ,  B01D2325/02 ,  B01J21/18 ,  B01J37/0018 ,  B01J37/084 ,  C04B35/524 ,  C04B35/64 ,  C04B35/806 ,  C04B35/82 ,  C04B35/83 ,  C04B38/04 ,  C04B2111/00612 ,  C04B2111/0081 ,  C04B2111/00836 ,  C04B2111/56 ,  C04B2235/3418 ,  C04B2235/663 ,  C04B2235/77 ,  C04B2235/94 ,  C07K16/00 ,  C07K16/1203 ,  C12M25/14 ,  C12N5/0068 ,  C12N2533/10 ,  C04B35/52 ,  C04B38/0032 ,  C04B41/45 ,  C04B2103/0067 ,  C04B2103/0099

摘要： The present invention relates to methods for producing carbon-based molded bodies. In particular, the present invention relates to methods for producing porous carbon-based molded bodies by carbonizing organic polymer materials mixed with non-polymeric fillers and subsequently dissolving the fillers out from the carbonized molded bodies. The present invention further relates to methods for producing porous carbon-based molded bodies by carbonizing organic polymer materials mixed with non-polymeric fillers which are substantially completely decomposed during the carbonization. The present invention also relates to a method for producing porous carbon-based molded bodies by carbonizing organic polymer materials, the carbon-based molded bodies being partially oxidized following carbonization so as to produce pores. In addition, the present invention relates to porous molded bodies produced according to one of said methods and the use thereof, especially as cell culture carriers and/or culture systems.

摘要翻译： 本发明涉及碳基成型体的制造方法。 特别地，本发明涉及通过碳化与非聚合物填料混合的有机聚合物材料并随后将填料从碳化模制体中溶出来生产多孔碳基成型体的方法。 本发明还涉及通过碳化与碳化过程中基本完全分解的非聚合物填料混合的有机聚合物材料来生产多孔碳基成型体的方法。 本发明还涉及通过碳化有机聚合物材料生产多孔碳基成型体的方法，碳基成型体在碳化后被部分氧化以产生孔。 此外，本发明涉及根据所述方法之一制备的多孔成型体及其用途，特别是作为细胞培养载体和/或培养系统。

公开(公告)号：US20090032612A1

公开(公告)日：2009-02-05

申请号：US10585568

申请日：2005-01-05

申请人： Jurgen Kunstmann ,  Jorg Rathenow ,  Soheil Asgari

发明人： Jurgen Kunstmann ,  Jorg Rathenow ,  Soheil Asgari

IPC分类号： B05B17/06

CPC分类号： B05B17/0607 ,  B05B5/087 ,  B05B14/00 ,  B05B16/20

摘要： A high-frequency spray device is provided that is suitable for applying a coating fluid onto a substrate. The spray device can include an atomizing arrangement, a movable substrate holder, a gas supply, and one or more temperature control elements. The atomizing arrangement can include a resonance body which may have a trumpet-like shape and which can be excited to produce high-frequency vibrations that may provide a spray mist jet of the coating fluid. The spray device can further include a field arrangement capable of generating an electric and/or magnetic field in the region containing the substrate which may influence the deposition of the spray mist jet on the substrate. The spray device may also include a suction arrangement that can affect the shape of the spray jet mist and/or withdraw a portion of the spray jet mist.

摘要翻译： 提供了一种适用于将涂布液施加到基底上的高频喷射装置。 喷雾装置可以包括雾化装置，可移动衬底保持器，气体供应器和一个或多个温度控制元件。 雾化装置可以包括共振体，其可以具有喇叭状形状并且可以被激发以产生可能提供喷涂雾喷射喷涂流体的高频振动。 喷射装置还可以包括能够在包含基底的区域中产生电场和/或磁场的场布置，其可影响喷雾喷射在基底上的沉积。 喷雾装置还可以包括能够影响喷射喷雾的形状和/或抽出喷射喷雾的一部分的抽吸装置。

公开(公告)号：US20080127821A1

公开(公告)日：2008-06-05

申请号：US11176611

申请日：2005-07-07

申请人： Andreas Noack ,  Jurgen Kunstmann ,  Christian Gnabs ,  Norman Bischofberger ,  Norbert A. Paul ,  Jorg Rathenow

发明人： Andreas Noack ,  Jurgen Kunstmann ,  Christian Gnabs ,  Norman Bischofberger ,  Norbert A. Paul ,  Jorg Rathenow

IPC分类号： B01D53/22

CPC分类号： B01D53/22 ,  Y02C10/04 ,  Y02C10/08 ,  Y02C10/10

摘要： The invention relates to a method for reducing the carbon dioxide concentration in air of a closed or partially closed unit of space. The inventive method may comprise the steps of removing an air flow from the unit of space, guiding the air flow in a membrane system that may contain at least one membrane module having a CO2/O2 selectivity of greater than 2, removing the carbon dioxide permeated through the membrane, and returning the air flow that has been depleted of carbon dioxide in the membrane system to the unit of space. The inventive method may be optionally combined with an oxygen enrichment method. The invention also relates to corresponding devices for carrying out the inventive method.

摘要翻译： 本发明涉及一种降低空气中空气中二氧化碳浓度的方法，该方法是封闭或部分封闭的空间单元。 本发明的方法可以包括以下步骤：从空间单元去除空气流，引导膜系统中的空气流，所述膜系统可以包含至少一个具有CO 2 2 O 2的膜组件， 2的选择性大于2，去除透过膜的二氧化碳，并将已经耗尽二氧化碳的膜流系统中的空气流返回到空间。 本发明的方法可以任选地与富氧方法组合。 本发明还涉及用于实施本发明方法的相应设备。