摘要:
The present invention is directed to compounds of Formula I pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.
摘要:
The present invention is directed to compounds of Formula I pharmaceutical compositions comprising the same, and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS.
摘要:
A winged visor stiffener for a hat's bill. A flat horizontal front section is connected to two angled offset sections. Two flat horizontal wings are connected to the two angled offset sections. The winged visor stiffener is sewn into the hat's bill via a plurality of rows of tight stitching. The winged visor stiffener provides protection to the wearer's face from the sun while optimizing peripheral vision and prevents the bill from flopping up or down in wet and windy conditions.
摘要:
A hat having a removable chin strap for the hat's brim. The flexible strap has end pieces connected to its ends. The strap also has a strap position lock device. Additionally, the strap includes an attachment clip that can be utilized for connecting the strap to the wearer's clothing. In one preferred embodiment the attachment clip is an alligator clip. In another preferred embodiment the attachment clip is a hook clip. Also, in a preferred embodiment the hat's brim includes a plurality of slots and the flexible strap is inserted through the slots and retained to the brim by the end pieces.
摘要:
In one embodiment, a system comprises a source configured to provide data and a source error correction code (ECC) generated according to a source ECC scheme; a circuit comprising an ECC transform unit configured to generate a target ECC from the data, detect an error in the data responsive to the source ECC, and correct the error in the data, wherein the target ECC is generated according to a target ECC scheme different from the source ECC scheme, and wherein the ECC transform unit is configured to continuously protect the data with at least one of the source ECC and the target ECC; and a target coupled to receive the data and the target ECC from the circuit.
摘要:
A device configured to recover and repeat source synchronous data. In one embodiment, the device is configured to receive source synchronous data via a first interface, recover the received data utilizing a corresponding received source synchronous clock signal, and transmit the recovered data and a corresponding clock signal in a source synchronous manner. In one embodiment, the device is configured to operate as a repeater without benefit of an internal clock signal. In addition, the device may be configured to remove data jitter and renew or restore amplitude to attenuated signals prior to retransmission.
摘要:
A winged visor stiffener for a hat's bill. A flat horizontal front section is connected to two angled offset sections. Two flat horizontal wings are connected to the two angled offset sections. The winged visor stiffener is sewn into the hat's bill via a plurality of rows of tight stitching. The winged visor stiffener provides protection to the wearer's face from the sun while optimizing peripheral vision and prevents the bill from flopping up or down in wet and windy conditions.
摘要:
An electromagnetic hydraulic valve (1) is provided having a valve housing (2) with a pressurized hydraulic medium inlet channel (24), a pressurized hydraulic medium outlet channel (25), a magnet coil (3), and a valve seat (23), with a magnet armature (9) that can be excited by the magnet coil and a valve tappet (10, 10′) fixed on this armature. A valve-closing element (13) is activated by the valve tappet and that blocks the connection between the pressurized hydraulic medium channels for contact on the valve seat. The magnet armature with the valve tappet and the valve-closing element are guided so that they can move longitudinally in the valve housing and the valve tappet and the valve-closing element contact each other with facing longitudinal end sides (26, 27) in a way that is free from tensile forces. Here, one annular, continuous lobe or several lobes (28, 28′) separated from each other are formed on the longitudinal end side of the valve tappet, which span a contact plane running perpendicular to a longitudinal direction of movement for the longitudinal end side of the valve-closing element.
摘要:
The present invention relates to tetrahydroquinoline derivatives having general formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is formyl, (1-6C)alkylcarbonyl or (1-6C)alkylsulfonyl; R2 and R3 are H or (1-4C)alkyl; R4 is phenyl; R5 is (1-4C)alkyl; Y—X is C(O)—O, S(O)2-O, NHC(O)—O, NHC(S)—O, OC(O)—O, bond-O, C(O)—NH, S(O)2-NH, NHC(O)—NH, NHC(S)—NH, OC(O)—NH, bond-NH, NH—C(O), O—C(O), NH—S(O)2, or O—S(O)2 or Y—X is a bond; R6 is H, trifluoromethyl, (1-6C)alkyl, 1- or 2-adamantyl(1-4C)alkyl, (2-6C)alkenyl, (2-6C)alkynyl, (3-9C)heteroaryl, (3-6C)cycloalkyl, (2-6C)heterocycloalkyl, (1-4C)alkylthio(1-4C)alkyl, (6-10C)aryl(1-4C)alkyl, (3-9C)heteroaryl(1-4C)alkyl, (3-6C)cycloalkyl(1-4C)alkyl, (2-6C)heterocycloalkyl(1-4C)alkyl, R8,R9-aminocarbonyl(1-4C)alkyl, R8,R9-amino(1-4C)alkyl, R8-oxycarbonyl(1-4C)alkyl, R8-oxy(1-4C)alkyl, R8-carbonyl(1-4C)alkyl or (6-10C)aryl; R7 is H, (1-4C)alkyl, (1-4C)alkoxy, halogen, trifluoromethyl, cyano, nitro, hydroxyl; and R8 and/or R9 is H, (1-4C)alkyl, (2-4C)alkenyl, (2-4C)alkynyl, (6-10C)aryl, (3-9C)heteroaryl, (6-10C)aryl(1-4C)alkyl, (3-9C)heteroaryl(1-4C)alkyl, (3-6C)cycloalkyl(1-4C)alkyl, (2-6C)heterocycloalkyl(1-4C)alkyl, (1-4C)(di)alkylamino(1-4C)alkyl, (1-4C)alkoxy(1-4C)alkyl, (1-4C)alkylthio(1-4C)alkyl, (1-4C)alkylcarbonylamino(1-4C)alkyl, (1-4C)alkoxycarbonyl(1-4C)alkyl, (1-4C)alkoxycarbonylamino(1-4C)alkyl, (3-6C)cycloalkyl, (2-6C)heterocycloalkyl, or R8 and R9 may be joined in a (2-6C)heterocycloalkyl ring. The present invention also relates to pharmaceutical compositions comprising said derivatives and the use of these derivatives to control fertility.
摘要:
A computer system including a memory controller configured to perform pre-fetch operations. A computer system includes a first system memory, a second system memory and a first and a second memory controller which are coupled to the first and second system memories, respectively. Each system memory may include at least one memory module including volatile storage. The first memory controller may be configured read data from the first system memory corresponding to an address of a current memory request. Further the second memory controller may be configured to selectively pre-fetch data from the second system memory depending upon selected address bits of the address of the current memory request.