公开(公告)号：US20160116408A1

公开(公告)日：2016-04-28

申请号：US14893961

申请日：2014-05-30

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Josephus Arnoldus Henricus Maria KAHLMAN ,  Nicolaas LAMBERT ,  Hans Willem VAN KESTEREN

IPC: G01N21/64 ,  G01N33/84 ,  G01N33/497

CPC classification number: G01N21/6408 ,  A61B5/1468 ,  G01N21/6428 ,  G01N21/77 ,  G01N33/497 ,  G01N33/84 ,  G01N2021/6439 ,  G01N2021/6441 ,  G01N2021/775 ,  G01N2021/7786 ,  G01N2201/062 ,  G01N2201/13

Abstract: The present invention relates to a method for optically determining the concentration of a gas, using at least two luminescent dyes, the first being in-sensitive to the concentration of a gas with respect to the luminescence response (reference dye) and the second being sensitive to the concentration of a gas with respect to the luminescence response (indicator dye), wherein said dyes show different luminescence decay times so that the resultant phase angle is indicative for the concentration of a gas, characterized in that the detected luminescent amplitude of the reference dye at a first moment in time is utilized to correct for sensitivity changes after said moment. The present invention also relates to a corresponding method for quality assessment of the measurement of an optical sensor for determining the concentration of a gas.

Abstract translation: 本发明涉及一种使用至少两种发光染料光学测定气体浓度的方法，其中第一种与气体的浓度对应于发光响应（参考染料）敏感，而第二种是敏感的 相对于发光响应（指示剂染料）的气体浓度，其中所述染料显示不同的发光衰减时间，使得所得到的相位角指示气体的浓度，其特征在于检测到的参考的发光振幅 利用第一时刻的染料来校正所述时刻之后的灵敏度变化。 本发明还涉及用于确定气体浓度的光学传感器的测量的质量评估的相应方法。

公开(公告)号：US20160135723A1

公开(公告)日：2016-05-19

申请号：US14895937

申请日：2014-06-06

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Josephus Arnoldus Henricus Maria KAHLMAN ,  Hans Willem VAN KESTEREN ,  Nicolaas LAMBERT

IPC: A61B5/1455

CPC classification number: A61B5/14552 ,  A61B5/14542 ,  A61B5/14551 ,  G01N33/004

Abstract: The present invention relates to a chemo-optical sensor unit for transcutaneous measurement of a concentration of a gas, comprising: at least one sensing layer adapted to be irradiated with a predetermined radiation; and at least one gas-permeable layer adjacent to one side of the at least one sensing layer, adapted to pass gas whose concentration is to be measured through the gas-permeable layer towards the sensing layer; wherein said chemo-optical sensor unit is adapted to operate with a contact medium between the gas-permeable layer and the skin, wherein said contact medium comprises a first compound other than water; wherein said chemo-optical sensor unit is characterized in that said at least one gas-permeable layer and said at least one sensing layer are permeable to said first compound; and wherein the chemo-optical sensor unit is adapted to measure an optical response of the at least one sensing layer, whose optical response depends on the concentration of the gas. The present invention also relates to a system comprising such a chemo-optical sensor, as well as to a method for conditioning a chemo-optical sensor unit for measuring a concentration of a gas and a thereby obtainable conditioned sensor.

Abstract translation: 本发明涉及一种用于透气测量气体浓度的化学光学传感器单元，包括：至少一个适于用预定辐射照射的感测层; 以及与所述至少一个感测层的一侧相邻的至少一个气体可渗透层，其适于将通过所述透气层测量的浓度的气体通向所述感测层; 其中所述化学光学传感器单元适于在气体可渗透层和皮肤之间与接触介质一起操作，其中所述接触介质包含不同于水的第一化合物; 其中所述化学光学传感器单元的特征在于，所述至少一个透气层和所述至少一个感测层对所述第一化合物是可渗透的; 并且其中所述化学光学传感器单元适于测量所述至少一个感测层的光学响应，其光学响应取决于所述气体的浓度。 本发明还涉及包括这种化学光学传感器的系统，以及用于调节化学光学传感器单元的方法，用于测量气体浓度和由此获得的调节传感器。

公开(公告)号：US20190090763A1

公开(公告)日：2019-03-28

申请号：US16083574

申请日：2017-03-21

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Pierre Hermanus WOERLEE ,  Paul AELEN ,  Maarten Petrus Joseph KUENEN ,  Nicolaas LAMBERT

IPC: A61B5/0225 ,  A61B5/022 ,  A61B5/107 ,  A61B5/0295 ,  A61B5/00

Abstract: There is provided a blood pressure monitor for use in measuring the blood pressure of a subject, the blood pressure monitor comprising a cuff that is configured to be placed around a body part of the subject and inflated to apply pressure to the body part; a pressure sensor that is configured to provide measurements of the pressure in the cuff; a plethysmography sensor comprising a coil having one or more windings that is configured to provide an output signal indicating the volume of the body part of the subject and/or changes in the volume of the body part; and a processing unit that is configured to determine the blood pressure of the subject from the measurements of the pressure in the cuff and the measurements of the volume of the body part and/or the changes in the volume of the body part. A corresponding method claim is also provided.

公开(公告)号：US20160007894A1

公开(公告)日：2016-01-14

申请号：US14760366

申请日：2013-12-30

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Josephus Arnoldus Henricus Maria KAHLMAN ,  Hans Willem VAN KESTEREN ,  Nicolaas LAMBERT ,  Theodorus Petrus Henricus Gerardus JANSEN

IPC: A61B5/1455 ,  A61B5/00 ,  A61B5/1491 ,  G01N33/00 ,  G01N21/59

CPC classification number: A61B5/14552 ,  A61B5/14556 ,  A61B5/1491 ,  A61B5/6833 ,  G01N21/59 ,  G01N33/004 ,  G01N2201/062

Abstract: The present invention provides an optical sensor unit (10) for measuring gas concentration, comprising: sensor means (12, 13) and first thermal insulation means (14, 16) at least partially surrounding said sensor means (12, 13). The sensor means (12,13) includes at least one sensing layer (12) adapted to be irradiated with a predetermined radiation (100), and at least one gas-permeable layer (13) adjacent to one side of the at least one sensing layer (12) and adapted to pass gas, which concentration is to measured, through the gas-permeable layer (13) towards the at least one sensing layer (12). The optical sensor unit (10) is adapted to measure an optical response of the at least one sensing layer (12), which optical response depends on the gas concentration.

Abstract translation: 本发明提供了一种用于测量气体浓度的光学传感器单元（10），包括：至少部分地围绕所述传感器装置（12,13）的传感器装置（12,13）和第一绝热装置（14,16）。 传感器装置（12,13）包括适于用预定辐射（100）照射的至少一个感测层（12），以及至少一个与所述至少一个传感器的一侧相邻的透气层（13） 层（12）并且适于使所述浓度被测量的气体通过透气层（13）朝着至少一个感测层（12）传递。 光学传感器单元（10）适于测量至少一个感测层（12）的光学响应，该光学响应取决于气体浓度。

公开(公告)号：US20190386709A1

公开(公告)日：2019-12-19

申请号：US16468116

申请日：2017-12-24

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Pierre Hermanus WOERLEE ,  Josephus Arnoldus Henricus Maria KAHLMAN ,  Nicolaas LAMBERT

IPC: H04B5/00 ,  H04B5/02

Abstract: The present invention relates to a device (700a, 700b, 700c) for wireless transmission of data and/or power between the device and another device of a system, in particular of a patient monitoring system. To meet stringent relative time errors at low complexity the device comprises a connector (701) comprising a data transmission unit (703) and a magnetic coupling unit (702, 704) for transmitting power to and/or receiving power. A detection unit (705) detects coupling of a counterpart connector of another device of the system with the connector (701). A control unit (707) uses the detection that a counterpart connector of another device of the system has been coupled with the connector (701) as a trigger to determine and/or reset a relative time difference between a clock signal used by the device and a clock signal of the other device using i) the high frequency power signal of the magnetic coupling unit (702, 704) and of a magnetic coupling unit of the counterpart connector and/or ii) a received time calibration signal for determining and/or resetting the relative time difference.

公开(公告)号：US20180098747A1

公开(公告)日：2018-04-12

申请号：US15574164

申请日：2016-05-17

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Nicolaas LAMBERT ,  Bart KROON ,  Alexander Franciscus KOLEN ,  Denny MATHEW ,  Rick BEZEMER

IPC: A61B8/06 ,  A61B8/00 ,  A61B8/08 ,  A61B8/15 ,  A61B5/024 ,  A61B5/00

Abstract: Apparatus and method comprising an ultrasound transmitter, for placement at a first location on the body of a subject, to emit an ultrasound pulse; an ultrasound receiver, for placement at a second location on the body, to detect an emitted ultrasound pulse; and a controller in communication with the transmitter and receiver. The controller causes an ultrasound pulse to be emitted by the transmitter; receives a measurement signal from the receiver; determines, based on the received measurement signal, a time of arrival at the receiver, T1 s of a first part of the emitted ultrasound pulse; determines, based on the received measurement signal, a time of arrival at the receiver, T2, of a second part of the ultrasound pulse; and calculates, using T1 and T2, a flow velocity of blood in a blood vessel between the first location and the second location.

公开(公告)号：US20200008699A1

公开(公告)日：2020-01-09

申请号：US16491224

申请日：2018-03-08

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Frank VERBAKEL ,  Nicolaas LAMBERT ,  Josephus Arnoldus Henricus Maria KAHLMAN ,  Pierre Hermanus WOERLEE ,  Marc Andre DE SAMBER

IPC: A61B5/0428 ,  H01B7/00 ,  H01B1/02 ,  H02G15/02

Abstract: The present invention relates to an ECG cable for connection with an ECG monitor. To achieve a miniaturization of the ECG cable and omitting the conventionally used trunk cable and trunk cable connector, the ECG cable comprises a core (2), a resistive wire cable (3a-3h) comprising a plurality of resistive wires (31-37) wound around the core and isolated with respect to each other, and two or more flexible lead wires (4), each connected to a respective resistive wire at its one end (40) and to an electrode (5) at its other end (41).

公开(公告)号：US20190175047A1

公开(公告)日：2019-06-13

申请号：US16324133

申请日：2017-08-14

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Frank VERBAKEL ,  Nicolaas LAMBERT ,  Hugo VEENSTRA ,  Marc Andre DE SAMBER ,  Josephus Arnoldus Henricus Maria KAHLMAN ,  Pierre Hermanus WOERLEE

IPC: A61B5/0428

Abstract: The present invention relates to an adapter (100) for coupling with a medical coupling unit (1) and a medical sensor (2) that are configured for being coupled for electrical signal transmission between them. The adapter comprises an adapter coupling unit (101) configured to fit with a coupling-side connector (10) of the medical coupling unit (1) and including a plurality of coupling-side electrical contacts (111, 113) for contacting a plurality of electrical contacts (11, 13) of the coupling-side connector (10) and a sensor-side connector (120) configured to fit with a sensor-side connector (20) of the medical sensor (2) and including a plurality of sensor-side electrical contacts (121, 123) for contacting a plurality of electrical contacts (21, 23) of the sensor-side connector (20), allowing the adapter coupling unit (101) to be mechanically coupled between the medical coupling unit (1) and the medical sensor (2). Further, the adapter comprises one or more wires (102) fixedly connected to the adapter coupling unit for coupling one or more sensor elements (225) with the adapter coupling unit for electrical signal transmission from the one or more sensor elements to the adapter coupling unit, and connection circuitry (103) within the adapter coupling unit (101) for connecting said sensor-side electrical contacts (121, 123) and said one or more wires (102) with said coupling-side electrical contacts (111, 113) allowing signal transmission from the medical sensor (2) and one or more sensor elements (225) coupled to the adapter coupling unit (101) to the medical coupling unit (1).

公开(公告)号：US20160081605A1

公开(公告)日：2016-03-24

申请号：US14892217

申请日：2014-06-06

Applicant: KONINKLIJKE PHILIPS N.V.

Inventor： Josephus Arnoldus Henricus Maria KAHLMAN ,  Nicolaas LAMBERT ,  Hans Willem VAN KESTEREN

IPC: A61B5/1455 ,  A61M16/00 ,  A61B5/1477

CPC classification number: A61B5/14556 ,  A61B5/145 ,  A61B5/1455 ,  A61B5/1477 ,  A61M16/0069 ,  G01N33/004

Abstract: The present invention relates to a chemo-optical sensor unit for transcutaneous measurement of a concentration of a gas, comprising: at least one sensing layer adapted to be irradiated with a predetermined radiation; and at least one gas-permeable layer adjacent to one side of the at least one sensing layer, adapted to pass gas whose concentration is to be measured through the gas-permeable layer towards the sensing layer; wherein said chemo-optical sensor unit is adapted to operate with a contact medium between the gas-permeable layer and the skin, wherein said contact medium comprises a barrier layer which is gas- permeable and impermeable to water and ions; and wherein the chemo-optical sensor unit is adapted to measure an optical response of the at least one sensing layer, whose optical response depends on the concentration of the gas. The present invention also relates to a system comprising such a chemo-optical sensor, as well as to a method for conditioning a chemo-optical sensor unit for measuring a concentration of a gas and a thereby obtainable conditioned sensor.

Abstract translation: 本发明涉及一种用于透气测量气体浓度的化学光学传感器单元，包括：至少一个适于用预定辐射照射的感测层; 以及与所述至少一个感测层的一侧相邻的至少一个气体可渗透层，其适于将通过所述透气层测量的浓度的气体通向所述感测层; 其中所述化学光学传感器单元适于与透气层和皮肤之间的接触介质一起操作，其中所述接触介质包括阻挡层，所述阻挡层是气体可渗透的并且不透水和离子; 并且其中所述化学光学传感器单元适于测量所述至少一个感测层的光学响应，其光学响应取决于所述气体的浓度。 本发明还涉及包括这种化学光学传感器的系统，以及用于调节化学光学传感器单元的方法，用于测量气体浓度和由此获得的调节传感器。