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17 条记录 (耗时 0.029 秒)

    ATR-2 cell cycle checkpoint
    1.
    发明授权
    ATR-2 cell cycle checkpoint 失效
    ATR-2细胞周期检查点

    公开(公告)号：US06815532B2

    公开(公告)日：2004-11-09

    申请号：US09957837

    申请日：2001-09-21

    申请人： Kate Loughney ,  Kathleen S. Keegan

    发明人： Kate Loughney ,  Kathleen S. Keegan

    IPC分类号： C07K100

    CPC分类号： C12N9/12

    摘要： Polynucleotides encoding novel Atr-2 cell cycle checkpoint polypeptides are disclosed, along with expression constructs comprising the polynucleotides, host cells transformed with the expression constructs, methods to make the Atr-2 polypeptides using the host cells, Atr-2 polypeptides, and binding partners of the Atr-2 polypeptides.

    ATR-2 cell cycle checkpoint
    2.
    发明授权
    ATR-2 cell cycle checkpoint 失效
    ATR-2细胞周期检查点

    公开(公告)号：US06344549B1

    公开(公告)日：2002-02-05

    申请号：US09417822

    申请日：1999-10-14

    申请人： Kate Loughney ,  Kathleen S. Keegan

    发明人： Kate Loughney ,  Kathleen S. Keegan

    IPC分类号： C07H2104

    CPC分类号： C12N9/12

    摘要： Polynucleotides encoding novel Atr-2 cell cycle checkpoint polypeptides are disclosed, along with expression constructs comprising the polynucleotides, host cells transformed with the expression constructs, methods to make the Atr-2 polypeptides using the host cells, Atr-2 polypeptides, and binding partners of the Atr-2 polypeptides.

    摘要翻译： 公开了编码新型Atr-2细胞周期检查点多肽的多核苷酸，以及包含多核苷酸的表达构建体，用表达构建体转化的宿主细胞，使用宿主细胞制备Atr-2多肽的方法，Atr-2多肽和结合配偶体 的Atr-2多肽。

    Atr-2 cell cycle checkpoint
    3.
    发明申请
    Atr-2 cell cycle checkpoint 审中-公开
    Atr-2细胞周期检查点

    公开(公告)号：US20050112643A1

    公开(公告)日：2005-05-26

    申请号：US10954723

    申请日：2004-09-30

    申请人： Kate Loughney ,  Kathleen Keegan

    发明人： Kate Loughney ,  Kathleen Keegan

    IPC分类号： C12N9/12 ,  C12N15/54 ,  C12Q1/68 ,  C07H21/04 ,  G01N33/574

    CPC分类号： C12N9/12

    摘要： Polynucleotides encoding novel Atr-2 cell cycle checkpoint polypeptides are disclosed, along with expression constructs comprising the polynucleotides, host cells transformed with the expression constructs, methods to make the Atr-2 polypeptides using the host cells, Atr-2 polypeptides, and binding partners of the Atr-2 polypeptides.

    摘要翻译： 公开了编码新型Atr-2细胞周期检查点多肽的多核苷酸，以及包含多核苷酸的表达构建体，用表达构建体转化的宿主细胞，使用宿主细胞制备Atr-2多肽的方法，Atr-2多肽和结合配偶体 的Atr-2多肽。

    Phosphodiesterase 10
    5.
    发明授权
    Phosphodiesterase 10 失效
    磷酸二酯酶10

    公开(公告)号：US06864070B2

    公开(公告)日：2005-03-08

    申请号：US10083620

    申请日：2002-02-26

    申请人： Kate Loughney

    发明人： Kate Loughney

    IPC分类号： G01N33/50 ,  A61K38/00 ,  A61K39/395 ,  A61K45/00 ,  A61P43/00 ,  C07K16/40 ,  C07K16/42 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/16 ,  C12N15/09 ,  C12N15/55 ,  C12P21/08 ,  C12Q1/68 ,  G01N33/15 ,  G01N33/566

    CPC分类号： C12N9/16 ,  A61K38/00

    摘要： The present invention provides novel human PDE10 polypeptides, polynucleotides encoding the polypeptides, expression constructs comprising the polynucleotides, host cells transformed with the expression constructs; methods for producing PDE10 polypeptides; antisense polynucleotides; and antibodies specifically immunoreactive with the PDE10 polypeptides. The invention further provides methods to identify binding partners of PDE 10, and more particularly, binding partners that modulate PDE10 enzyme activity.

    摘要翻译： 本发明提供新的人PDE10多肽，编码多肽的多核苷酸，包含多核苷酸的表达构建体，用表达构建体转化的宿主细胞; 生产PDE10多肽的方法; 反义多核苷酸; 和与PDE10多肽特异性免疫反应的抗体。 本发明还提供了鉴定PDE10的结合配偶体的方法，更具体地，涉及调节PDE10酶活性的结合配偶体。

    Phosphodiesterase 10
    6.
    发明授权
    Phosphodiesterase 10 失效
    磷酸二酯酶10

    公开(公告)号：US06734003B2

    公开(公告)日：2004-05-11

    申请号：US10034015

    申请日：2001-12-20

    申请人： Kate Loughney

    发明人： Kate Loughney

    IPC分类号： C12N916

    CPC分类号： C12N9/16 ,  A61K38/00

    摘要： The present invention provides novel human PDE10 polypeptides, polynucleotides encoding the polypeptides, expression constructs comprising the polynucleotides, host cells transformed with the expression constructs; methods for producing PDE10 polypeptides; antisense polynucleotides; and antibodies specifically immunoreactive with the PDE10 polypeptides. The invention further provides methods to identify binding partners of PDE10, and more particularly, binding partners that modulate PDE10 enzyme activity.

    摘要翻译： 本发明提供新的人PDE10多肽，编码多肽的多核苷酸，包含多核苷酸的表达构建体，用表达构建体转化的宿主细胞; 生产PDE10多肽的方法; 反义多核苷酸; 和与PDE10多肽特异性免疫反应的抗体。 本发明进一步提供鉴定PDE10的结合配偶体的方法，更具体地，涉及调节PDE10酶活性的结合配偶体。

    Phosphodiesterase 8A
    7.
    发明授权
    Phosphodiesterase 8A 失效

    公开(公告)号：US06566087B1

    公开(公告)日：2003-05-20

    申请号：US09686055

    申请日：2000-10-11

    申请人： Kate Loughney

    发明人： Kate Loughney

    IPC分类号： C12Q100

    CPC分类号： C12N9/16

    摘要： The present invention provides novel human PDE8 polypeptides, polynucleotides encoding the polypeptides, expression constructs comprising the polynucleotides, host cells transformed with the expression constructs; methods for producing PDE8 polypeptides; antisense polynucleotides; and antibodies specifically immunoreactive with the PDE8 polypeptides.