摘要:
Trifluoromethylketone compounds of the formula: ##STR1## wherein R.sup.1 is C.sub.1-6 alkyl which has one or two substituents selected from carboxy, esterified carboxy and di-C.sub.1-6 alkylcarbamoyl; phenyl(C.sub.1-6)alkyl, the phenyl moiety of which may have halogen or nitro or amino substituents and the alkyl moiety of which may have carboxy or esterified carboxy substituents; halo-phenyl; morpholino; or morpholino(C.sub.1-6)alkyl, R.sup.2 and R.sup.3 are each C.sub.1-6 alkyl, X is --or --NH--, and ##STR2## and pharmaceutically acceptable salts thereof are useful for inhibiting human elastase.
摘要:
The trifluoromethylketone derivatives (I) and pharmaceutically acceptable salts thereof have a human leukocyte elastase inhibiting activity and are useful as human leukocyte elastase inhibitors for treating or preventing degenerative diseases. The trifluoromethylketone derivatives (I) have the following formula: ##STR1## wherein R.sup.1 is C.sub.1-6 alkyl which has one or two substituents selected from carboxy, esterified carboxy and di-C.sub.1-6 alkylcarbamoyl; phenyl(C.sub.1-6) alkyl, the phenyl moiety of which may have halogen or nitro or amino substituents and the alkyl moiety of which may have carboxy or esterified carboxy substituents; halo-phenyl; morpholino; or morpholino(C.sub.1-6) alkyl,R.sup.2 and R.sup.3 are each C.sub.1-6 alkyl,X is -- or --NH--, andY is ##STR2## and pharmaceutically acceptable salts thereof.
摘要:
A compound of the formula: ##STR1## wherein R.sup.1 is lower alkyl optionally substituted with a substituent selected from the group consisting of acyl, hydroxy, lower alkoxy, aryl, lower alkylthio and a group of the formula: ##STR2## in which R.sup.5 is hydrogen or acyl and R.sup.6 is hydrogen or lower alkyl; aryl; or amino optionally substituted with substituent(s) selected from the group consisting of lower alkyl and acyl; andR.sup.2 is hydrogen or lower alkyl; orR.sup.1 and R.sup.2 are taken together with the attached nitrogen atom to form a heterocyclic group optionally substituted with substituent(s) selected from the group consisting of lower alkyl, hydroxy(lower )alkyl, lower alkoxy(lower)alkyl, acyl(lower)alkyl, oxo and acyl;R.sup.3 is hydrogen or lower alkyl; andR.sup.4 is lower alkyl;and its pharmaceutically acceptable salt, processes for the preparation thereof and pharmaceutical composition comprising the same.
摘要:
A compound of the formula: ##STR1## wherein R.sup.1 is lower alkyl optionally substituted aryl; or amino optionally substituted; andR.sup.2 is hydrogen or lower alkyl; orR.sup.1 and R.sup.2 are taken together with the attached nitrogen atom to form a heterocyclic group optionally substituted;R.sup.3 is hydrogen or lower alkyl; andR.sup.4 is lower alkyl;and its pharmaceutically acceptable salt, processes for the preparation thereof and pharmaceutical composition comprising the same
摘要:
A compound of the formula: ##STR1## wherein R.sup.1 is aryl optionally substituted with a substituent selected from the group consisting of halogen and halo(lower)alkyl; lower alkyl or cyclo(lower)alkyl; andR.sup.2 is hydrogen or lower alkyl, orR.sup.1 and R.sup.2 are taken together with the attached nitrogen atom to form a heterocyclic group optionally substituted with a substituent selected from the group consisting of lower alkyl and esterified carboxy,R.sup.3 is hydrogen or lower alkyl, andR.sup.4 is lower alkyl,and its pharmaceutically acceptable salt, a process for the preparation thereof and pharmaceutical composition comprising the same.
摘要:
An optical encoder having a structure for preventing water or the like from adhering to a V-shaped groove of a code plate of the encoder. The optical encoder has a protective plate made from an optically transmissive material, the protective plate being positioned adjacent to a surface of the code plate on which the V-shaped groove is formed.
摘要:
The present invention relates to an optical sender applicable to WDM (wavelength division multiplexing), and a primary object of the present invention is to prevent interchannel crosstalk in WDM. The optical sender includes a light source for outputting a light beam, an optical modulator for modulating the light beam in accordance with a main signal to output an optical signal, and a unit for shutting down the optical signal when receiving at least one of a power alarm relating to on/off of power supply and a wavelength alarm relating to the wavelength of the light beam.
摘要:
The invention aims to reduce an error occurring due to the mounting condition of an acceleration sensor. In the case of a two-axis sensor, an angle θ is calculated from outputs (x′, y′) that the acceleration sensor produces when known accelerations (x, y) are applied, and the angle θ is stored in a storage device contained in a casing in which the acceleration sensor is housed. In the case of a one-axis sensor, the ratio of the magnitudes of accelerations is stored. The acceleration detected by the acceleration sensor is compensated by using the value stored in the storage device.
摘要:
A rotary disc for use in a rotary encoder includes a signal generation section having a pattern formed thereon to generate a signal indicative of a rotational angle/phase. The signal generation section has a peripheral surface, which is provided with a linear portion usable as an indicator indicative of the rotational angle/phase represented by the signal generation pattern on the signal generation section. A robot hand is employed to hold the linear portion and attach it through an attachment portion of the rotary disc to a rotor shaft of a motor.